1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 ------------------------------------------------------------
3 ---------MNGTE--GDNFYVP----FSNKTGLARSPYEYPQY-YLAEPWK--------
4 -YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVT
5 MYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGN
6 THAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESY
7 VVYMFVVHFLVPFVIIFFCYGRLLCTV---------------------------------
8 ------------------------------------------------------------
9 ------------------------------KEAAAAQQ----------ESASTQKA----
10 -------------------------EKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQGS
11 D---FGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCCGKN------PLGDDE
12 --SGASTSKTEVSSVS-TSPVSPA------------------------------------
13 ---------------------------------------------------
14 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
15 ------------------------------------------------------------
16 ---------MNGTE--GPNFYVP----FSNITGVVRSPFEQPQY-YLAEPWQ--------
17 -FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTT
18 LYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGE
19 NHAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESF
20 VIYMFVVHFTIPMIVIFFCYGQLVFTV---------------------------------
21 ------------------------------------------------------------
22 ------------------------------KEAAAQQQ----------ESATTQKA----
23 -------------------------EKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQGS
24 N---FGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCCGKN------PLGDDE
25 --ASATASKTE------TSQVAPA------------------------------------
26 ---------------------------------------------------
27 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
28 ------------------------------------------------------------
29 ---------MNGTE--GINFYVP----MSNKTGVVRSPFEYPQY-YLAEPWK--------
30 -YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVT
31 FYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSA
32 THAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESY
33 VLYMFVIHFIIPVVVIFFSYGRLICKV---------------------------------
34 ------------------------------------------------------------
35 ------------------------------REAAAQQQ----------ESATTQKA----
36 -------------------------EKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKGA
37 D---FTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICCGKN------PFGDED
38 VSSTVSQSKTEVSSVS-SSQVSPA------------------------------------
39 ---------------------------------------------------
40 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
41 ------------------------------------------------------------
42 ---------MNGTE--GKNFYVP----MSNRTGLVRSPFEYPQY-YLAEPWQ--------
43 -FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVT
44 FYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSS
45 SHAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESY
46 VIYMFVCHFILPVAVIFFTYGRLVCTV---------------------------------
47 ------------------------------------------------------------
48 ------------------------------KAAAAQQQ----------DSASTQKA----
49 -------------------------EREVTKMVILMVFGFLIAWTPYATVAAWIFFNKGA
50 D---FSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFCGKN------PLGDDE
51 -SSTVSTSKTEVSS------VSPA------------------------------------
52 ---------------------------------------------------
53 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
54 ------------------------------------------------------------
55 ---------MNGTE--GNNFYVP----LSNRTGLVRSPFEYPQY-YLAEPWQ--------
56 -FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVT
57 FYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSS
58 THASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESY
59 VLYMFICHFILPVTIIFFTYGRLVCTV---------------------------------
60 ------------------------------------------------------------
61 ------------------------------KAAAAQQQ----------DSASTQKA----
62 -------------------------EREVTKMVILMVLGFLVAWTPYATVAAWIFFNKGA
63 A---FSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFCGKN------PLGDEE
64 -SSTVSTSKTEVSS------VSPA------------------------------------
65 ---------------------------------------------------
66 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
67 ------------------------------------------------------------
68 ---------MKQVPEFHEDFYIPIPLDINNLS--AYSPFLVPQD-HLGNQGI--------
69 -FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLS
70 FYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKT
71 PHAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESY
72 VMFLFCFCFAVPFGTIVFCYGQLLITL---------------------------------
73 ------------------------------------------------------------
74 ------------------------------KLAAKAQA----------DSASTQKA----
75 -------------------------EREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRGE
76 E---FDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVCGKN-------IEEDE
77 --ASTSSQVTQVSS------VAPEK-----------------------------------
78 ---------------------------------------------------
79 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
80 ------------------------------------------------------------
81 ---------MRKMS--EEEFYL-----FKNISSV--GPWDGPQY-HIAPVWA--------
82 -FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPV
83 FVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSS
84 KHALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESY
85 TWFLFIFCFIVPLSLICFSYTQLLRAL---------------------------------
86 ------------------------------------------------------------
87 ------------------------------KAVAAQQQ----------ESATTQKA----
88 -------------------------EREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNH
89 G---LDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVCGKA-------MTDES
90 --DTCSSQKTEVSTVS-STQVGPN------------------------------------
91 ---------------------------------------------------
92 > 8=opsin, greensensitive human (fragment) S07060
93 ------------------------------------------------------------
94 ------------------------------------------------------------
95 -----------------------------------------------DLAETVIA-STIS
96 IVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDA
97 KLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSY
98 MIVLMVTCCITPLSIIVLCYLQVWLAI---------------------------------
99 ------------------------------------------------------------
100 ------------------------------RAVAKQQK----------ESESTQKA----
101 -------------------------EKEVTRMVVVMVLAFC-------------------
102 ------------------------------------------------------------
103 ------------------------------------------------------------
104 ---------------------------------------------------
105 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
106 ----------------------------------------------------------MA
107 QQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNS-TRGPFEGPNY-HIAPRWV--------
108 -YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STIS
109 VVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDA
110 KLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSY
111 MIVLMVTCCITPLSIIVLCYLQVWLAI---------------------------------
112 ------------------------------------------------------------
113 ------------------------------RAVAKQQK----------ESESTQKA----
114 -------------------------EKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGY
115 P---FHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF-----------GKKVDD
116 GSELSSASKTEVSSV---SSVSPA------------------------------------
117 ---------------------------------------------------
118 > 10== Z68193 1 human Red Opsin <>[]
119 ----------------------------------------------------------MA
120 QQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNS-TRGPFEGPNY-HIAPRWV--------
121 -YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STIS
122 IVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDA
123 KLAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSY
124 MIVLMVTCCIIPLAIIMLCYLQVWLAI---------------------------------
125 ------------------------------------------------------------
126 ------------------------------RAVAKQQK----------ESESTQKA----
127 -------------------------EKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGY
128 A---FHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF-----------GKKVDD
129 GSELSSASKTEVSSV---SSVSPA------------------------------------
130 ---------------------------------------------------
131 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
132 ----------------------------------------------------------MT
133 EAWNVAVFAARRSRDD-DDTTRGSVFTYTNTNN-TRGPFEGPNY-HIAPRWV--------
134 -YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STIS
135 VFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDS
136 KLAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSF
137 MLTLMITCCFLPLFIIIVCYLQVWMAI---------------------------------
138 ------------------------------------------------------------
139 ------------------------------RAVAAQQK----------ESESTQKA----
140 -------------------------EREVSRMVVVMIVAFCICWGPYASFVSFAAANPGY
141 A---FHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF-----------GKKVDD
142 GSEASTTSRTEVSSVS-NSSVAPA------------------------------------
143 ---------------------------------------------------
144 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
145 -----------------------------------------------------------M
146 AAWEAAFAARRRHEE--EDTTRDSVFTYTNSNN-TRGPFEGPNY-HIAPRWV--------
147 -YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STIS
148 VINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDG
149 KLAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSY
150 MVVLMVTCCFFPLAIIILCYLQVWLAI---------------------------------
151 ------------------------------------------------------------
152 ------------------------------RAVAAQQK----------ESESTQKA----
153 -------------------------EKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPGY
154 A---FHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF-----------GKKVDD
155 GSEVST-SRTEVSSVS-NSSVSPA------------------------------------
156 ---------------------------------------------------
157 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
158 ------------------------------------------------------------
159 ---------------------MSSNSSQAPPNG-TPGPFDGPQWPYQAPQST--------
160 -YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVS
161 LSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQR
162 RHAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGSNN--NSY
163 ILSLFVTCFVLPLSLILFSYTNLLLTL---------------------------------
164 ------------------------------------------------------------
165 ------------------------------RAAAAQQK----------EADTTQRA----
166 -------------------------EREVTRMVIVMVMAFLLCWLPYSTFALVVATHKGI
167 I---IQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGYQ------PQRTGK
168 ASPGTPGPHADVTAAGLRNKVMPAHPV---------------------------------
169 ---------------------------------------------------
170 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
171 ------------------------------------------------------MESGNV
172 SSSLFGNVSTALRPEARLSA---E-----TRLLGWNVPPEELR--HIPEHWLTYPEPPES
173 MNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIF
174 IYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTH
175 GKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDTRLF
176 VACIFFFSFVCPTTMITYYYSQIVGHVFSH------------------------------
177 ------------------------------------------------------------
178 -----------------------------EKALRDQAKKMNVESLRSNVDKNKETA----
179 -------------------------EIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKT
180 L---LTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL---------NEK
181 APESSAVASTSTTQEPQQTTAA--------------------------------------
182 ---------------------------------------------------
183 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
184 ------------------------------------------------------MEYHNV
185 SSVL-GNVSSVLRPDARLSA---E-----SRLLGWNVPPDELR--HIPEHWLIYPEPPES
186 MNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIF
187 IYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTH
188 GKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDTRLF
189 VACIFFFSFVCPTTMITYYYSQIVGHVFSH------------------------------
190 ------------------------------------------------------------
191 -----------------------------EKALRDQAKKMNVDSLRSNVDKSKEAA----
192 -------------------------EIRIAKAAITICFLFFASWTPYGVMSLIGAFGDKT
193 L---LTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI---------SEK
194 APESRAAISTSTTQEQQQTTAA--------------------------------------
195 ---------------------------------------------------
196 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
197 ------------------------------------------------------ME----
198 --PLCNASEPPLRPEAR-SSGNGD-----LQFLGWNVPPDQIQ--YIPEHWLTQLEPPAS
199 MHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF
200 --NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTF
201 TKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLF
202 VGTIFFFSFVCPTLMILYYYSQIVGHVFSH------------------------------
203 ------------------------------------------------------------
204 -----------------------------EKALREQAKKMNVESLRSNVDKSKETA----
205 -------------------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKS
206 L---LTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV---------NEK
207 SGEISSAQSTTTQEQ-QQTTAA--------------------------------------
208 ---------------------------------------------------
209 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
210 ------------------------------------------------------MD----
211 --ALCNASEPPLRPEARMSSGSDE-----LQFLGWNVPPDQIQ--YIPEHWLTQLEPPAS
212 MHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF
213 IYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTF
214 TKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLF
215 VGTIFLFSFVVPTLMILYYYSQIVGHVFNH------------------------------
216 ------------------------------------------------------------
217 -----------------------------EKALREQAKKMNVESLRSNVDKSKETA----
218 -------------------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKS
219 L---LTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV---------NEK
220 SGEASSAQSTTTQEQTQQTSAA--------------------------------------
221 ---------------------------------------------------
222 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
223 ------------------------------------------------------------
224 ---MTNATGPQMAYYGAASMDFGYPE---GVSIVDFVRPEIKP--YVHQHWYNYPPVNPM
225 WHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFF
226 TYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTT
227 GKAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNTFSY
228 NIFIFVFDYFLPAAIIVFSYVFIVKAIFAH------------------------------
229 ------------------------------------------------------------
230 -----------------------------EAAMRAQAKKMNVSTLRS-NEADAQRA----
231 -------------------------EIRIAKTALVNVSLWFICWTPYALISLKGVMGDTS
232 G---ITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV------HETETK
233 SNDDSQSNSTVAQDKA--------------------------------------------
234 ---------------------------------------------------
235 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
236 ------------------------------------------------------------
237 ---MANVTGPQMAFYGSGAATFGYPE---GMTVADFVPDRVKH--MVLDHWYNYPPVNPM
238 WHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPF
239 CYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQ
240 GKATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNTITY
241 NICIFIFDFFLPASVIVFSYVFIVKAIFAH------------------------------
242 ------------------------------------------------------------
243 -----------------------------EAAMRAQAKKMNVTNLRS-NEAETQRA----
244 -------------------------EIRIAKTALVNVSLWFICWTPYAAITIQGLLGNAE
245 G---ITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV------HEKDPN
246 DVEENQSSNTQTQEKS--------------------------------------------
247 ---------------------------------------------------
248 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
249 ---------------------------------------------------------MES
250 FAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH--LISPYWNQFPAMDPI
251 WAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMM
252 GINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTI
253 PLALGKM---------------------------YVPEGNLTSCGIDYLE--RDWNPRSY
254 LIFYSIFVYYIPLFLICYSYWFIIAAVSAH------------------------------
255 ------------------------------------------------------------
256 -----------------------------EKAMREQAKKMNVKSLRS-SEDAEKSA----
257 -------------------------EGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-E
258 G---LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDG
259 K-SSDAQSQATASEAESKA-----------------------------------------
260 ---------------------------------------------------
261 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
262 ---------------------------------------------------------MES
263 FAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH--LISPYWNQFPAMDPI
264 WAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMM
265 GINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTI
266 PLALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSY
267 LIFYSIFVYYIPLFLICYSYWFIIAAVSAH------------------------------
268 ------------------------------------------------------------
269 -----------------------------EKAMREQAKKMNVKSLRS-SEDAEKSA----
270 -------------------------EGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-E
271 G---LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDG
272 K-SSDAQSQATASEAESKA-----------------------------------------
273 ---------------------------------------------------
274 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
275 ---------------------------------------------------------MDS
276 FAAVATQLGPQFA-----APS--------NGSVVDKVTPDMAH--LISPYWDQFPAMDPI
277 WAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMM
278 GINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTI
279 PLALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSY
280 LIFYSIFVYYIPLFLICYSYWFIIAAVSAH------------------------------
281 ------------------------------------------------------------
282 -----------------------------EKAMREQAKKMNVKSLRS-SEDADKSA----
283 -------------------------EGKLAKVALVTISLWFMAWTPYLVINCMGLFKF-E
284 G---LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDG
285 K-SSEAQSQATTSEAESKA-----------------------------------------
286 ---------------------------------------------------
287 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
288 ----------------------------------------------------MERSHLPE
289 TPFDLAHSGPRFQ-----AQSSG------NGSVLDNVLPDMAH--LVNPYWSRFAPMDPM
290 MSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVM
291 IINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTI
292 KTSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNPRSY
293 LITYSLFVYYTPLFLICYSYWFIIAAVAAH------------------------------
294 ------------------------------------------------------------
295 -----------------------------EKAMREQAKKMNVKSLRS-SEDCDKSA----
296 -------------------------EGKLAKVALTTISLWFMAWTPYLVICYFGLFKI-D
297 G---LTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF------GNTDEP
298 KPDAPASDTETTSEADSKA-----------------------------------------
299 ---------------------------------------------------
300 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
301 ----------------------------------------------------MERSLLPE
302 PPLAMALLGPRFE-----AQTGG------NRSVLDNVLPDMAP--LVNPHWSRFAPMDPT
303 MSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVM
304 IINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTI
305 KTSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNPRSY
306 LITYSLFVYYTPLFMICYSYWFIIATVAAH------------------------------
307 ------------------------------------------------------------
308 -----------------------------EKAMRDQAKKMNVKSLRS-SEDCDKSA----
309 -------------------------ENKLAKVALTTISLWFMAWTPYLIICYFGLFKI-D
310 G---LTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC------GTTDEP
311 KPDAPPSDTETTSEAESKD-----------------------------------------
312 ---------------------------------------------------
313 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
314 ------------------------------------------------------------
315 ---MIAVSGPSYE-----AFSYGGQARFNNQTVVDKVPPDMLH--LIDANWYQYPPLNPM
316 WHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPM
317 VINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSI
318 NGALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLSASY
319 LVCYGIWVYFVPLFLIIYSYWFIIQAVAAH------------------------------
320 ------------------------------------------------------------
321 -----------------------------EKNMREQAKKMNVASLRS-SENQNTSA----
322 -------------------------ECKLAKVALMTISLWFMAWTPYLVINFSGIFNL-V
323 K---ISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC-------AAEPS
324 SDAVSTTSGTTTVTDNEKSNA---------------------------------------
325 ---------------------------------------------------
326 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
327 ------------------------------------------------------------
328 -----MANQLSYS-----SLGWPYQP---NASVVDTMPKEMLY--MIHEHWYAFPPMNPL
329 WYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTM
330 TSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTH
331 KKATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSSASY
332 VVIYGLAVYFLPLITMIYCYFFIVHAVAEH------------------------------
333 ------------------------------------------------------------
334 -----------------------------EKQLREQAKKMNVASLRANADQQKQSA----
335 -------------------------ECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSGT
336 R---LTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC------GSGESG
337 SDVKSEASATTTMEEKPKIPEA--------------------------------------
338 ---------------------------------------------------
339 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
340 ------------------------------------------------------------
341 ----------MVESTTLVNQTWWY-----NPTVD------------IHPHWAKFDPIPDA
342 VYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLK
343 TISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSH
344 RRAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPSTRSF
345 ILCMYFCGFMLPIIIIAFCYFNIVMSVSNH------------------------------
346 ------------------------------------------------------------
347 -----------------------------EKEMAAMAKRLNAKELR--KAQAGASA----
348 -------------------------EMKLAKISMVIITQFMLSWSPYAIIALLAQFGPAE
349 W---VTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECEDA
350 NDAEEEVVASER--GGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQ
351 GAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
352 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
353 ------------------------------------------------------------
354 -----------MGRDLRDNETWWY-----NPSIV------------VHPHWREFDQVPDA
355 VYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLM
356 TISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSH
357 RRAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTTRSN
358 ILCMFILGFFGPILIIFFCYFNIVMSVSNH------------------------------
359 ------------------------------------------------------------
360 -----------------------------EKEMAAMAKRLNAKELR--KAQAGANA----
361 -------------------------EMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLE
362 W---VTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDD
363 KDAETEIPAGESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQ
364 GY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
365 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
366 ---------MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLS-
367 --EVTASPAPTW------------DAPPDNASGCGEQIN-----------------YGRV
368 EKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFV
369 SVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNG
370 KCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GY
371 TIYSTAVAFYIPMSVMLFMYYQIYKAAR--------------------------------
372 ------------------KSAAKHKFPGFPRVEPDSVIAL--------------------
373 -----------------------------NGIVKLQKEVEECANLSRLL-----------
374 -------------KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT
375 SCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMH
376 EALKLAERPERPEFVLQNADYCRKKGHDS-------------------------------
377 ---------------------------------------------------
378 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
379 -----------------------------------------------------MPHLLSG
380 FLEVTASPAPTW------------DAPPDNVSGCGEQIN-----------------YGRV
381 EKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFV
382 SVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNG
383 KCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GY
384 TIYSTAVAFYIPMSVMLFMYYQIYKAAR--------------------------------
385 ------------------KSAAKHKFPGFPRVQPESVISL--------------------
386 -----------------------------NGVVKLQKEVEECANLSRLL-----------
387 -------------KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT
388 SCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYRNINRKLSAAGMH
389 EALKLAERPERSEFVLQNSDHCGKKGHDT-------------------------------
390 ---------------------------------------------------
391 > 31=p A47425 serotonin receptor 5HT-7 - rat
392 -----------------------------------------------------MPHLLSG
393 FLEVTASPAPTW------------DAPPDNVSGCGEQIN-----------------YGRV
394 EKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFV
395 SVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNG
396 KCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GY
397 TIYSTAVAFYIPMSVMLFMYYQIYKAAR--------------------------------
398 ------------------KSAAKHKFPGFPRVQPESVISL--------------------
399 -----------------------------NGVVKLQKEVEECANLSRLL-----------
400 -------------KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT
401 SCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMH
402 EALKLAERPERSEFVLQNSDHCGKKGHDT-------------------------------
403 ---------------------------------------------------
404 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
405 ----------MDVLSPGQ-------GN----------------------NTTSPPAPFET
406 GGNTTGISDVTV-----------------------------------------------S
407 YQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMA
408 ALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTP
409 RRAAALISLTWLIGFLI-SIPPMLG-WRTPEDRSDPDA---CTISKDH----------GY
410 TIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK---------------------------
411 ------------TVKKVEKTGADTRHGASPAPQPKKS-----------VNGESGSR----
412 -----NWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAG--PT
413 PCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CES
414 SCH-MPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ----------
415 ------------------------------------------------------------
416 ---------------------------------------------------
417 > 33=p A35181 serotonin receptor class 1A - rat
418 ----------MDVFSFGQ-------GN----------------------NTTASQEPFGT
419 GGNVTSISDVTF-----------------------------------------------S
420 YQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMA
421 ALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTP
422 RRAAALISLTWLIGFLI-SIPPMLG-WRTPEDRSDPDA---CTISKDH----------GY
423 TIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK---------------------------
424 ------------TVRKVEKKGAGTSLGTSSAPPPKKS-----------LNGQPGSG----
425 -----DWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESG--SN
426 SYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CES
427 SCH-MPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR----------
428 ------------------------------------------------------------
429 ---------------------------------------------------
430 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
431 MANFTFGDLALDVARMGGLASTPSGLR----------------------STGLTTPGLSP
432 TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATN-----MTDDRYWSLTVYSHE
433 HLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLS
434 VVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSA
435 RRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GY
436 TIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSV
437 VSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS-----
438 -----SERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS----
439 ---------RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDP
440 E-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR--------
441 ------------------------------------------------------------
442 ---------------------------------------------------
443 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
444 MANFTFGDLALDVARMGGLASTPSGLR----------------------STGLTTPGLSP
445 TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATN-----MTDDRYWSLTVYSHE
446 HLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLS
447 VVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSA
448 RRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GY
449 TIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSV
450 VSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS-----
451 -----SERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS----
452 ---------RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDP
453 E-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR--------
454 ------------------------------------------------------------
455 ---------------------------------------------------
456 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
457 -MEGAEGQEELDWEAL--YLRLP--LQ----------------------NCSWNSTGWEP
458 NWNVTVVPNTTW---------WQASAPFDTPAALVRAAAK--------------------
459 -----AVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLG
460 AVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTA
461 KRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GY
462 QIFATASSFYVPVLIILILYWRIYQTARKRIR----------------------------
463 -----------------RRRGATARGGVGPPP---------VPAGGALVAGGGSGGIAAA
464 VVAVIGRPLPTISETTTTGFTNVSS----NNTS---PEKQSCANGLEADPPTTGYGAVAA
465 AYYPSLVRRKPKEAADSK------RERKAAKTLAIITGAFVACWLPFFVLAILVPT-CDC
466 E---VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRVRRRRAPQ-----
467 ------------------------------------------------------------
468 ---------------------------------------------------
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