1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 ------------------------------------------------------------
3 ---------MNGTE--GDNFYVP----FSNKTGLARSPYEYPQYYLAEPWK---------
4 YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTM
5 YTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNT
6 HAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESYV
7 VYMFVVHFLVPFVIIFFCYGRLLCTV----------------------------------
8 ------------------------------------------------------------
9 -------------------KEAAAAQQ-----------------------------ESAS
10 TQKA----------EKEVTRMVVLMVIGFLVCWVPYASVAFYIFT---HQGSD-FGATFM
11 TLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCCGKN------PLGDDE--SGASTSKT
12 EVSSVS-TSPVSPA----------------------------------------------
13 -----------------------------------------
14 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
15 ------------------------------------------------------------
16 ---------MNGTE--GPNFYVP----FSNITGVVRSPFEQPQYYLAEPWQ---------
17 FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTL
18 YTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGEN
19 HAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESFV
20 IYMFVVHFTIPMIVIFFCYGQLVFTV----------------------------------
21 ------------------------------------------------------------
22 -------------------KEAAAQQQ-----------------------------ESAT
23 TQKA----------EKEVTRMVIIMVIFFLICWLPYASVAMYIFT---HQGSN-FGPIFM
24 TLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCCGKN------PLGDDE--ASATASKT
25 ETSQ------VAPA----------------------------------------------
26 -----------------------------------------
27 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
28 ------------------------------------------------------------
29 ---------MNGTE--GINFYVP----MSNKTGVVRSPFEYPQYYLAEPWK---------
30 YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTF
31 YTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSAT
32 HAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESYV
33 LYMFVIHFIIPVVVIFFSYGRLICKV----------------------------------
34 ------------------------------------------------------------
35 -------------------REAAAQQQ-----------------------------ESAT
36 TQKA----------EKEVTRMVILMVLGFMLAWTPYAVVAFWIFT---NKGAD-FTATLM
37 AVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICCGKN------PFGDEDVSSTVSQSKT
38 EVSSVS-SSQVSPA----------------------------------------------
39 -----------------------------------------
40 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
41 ------------------------------------------------------------
42 ---------MNGTE--GKNFYVP----MSNRTGLVRSPFEYPQYYLAEPWQ---------
43 FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTF
44 YTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSS
45 HAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESYV
46 IYMFVCHFILPVAVIFFTYGRLVCTV----------------------------------
47 ------------------------------------------------------------
48 -------------------KAAAAQQQ-----------------------------DSAS
49 TQKA----------EREVTKMVILMVFGFLIAWTPYATVAAWIFF---NKGAD-FSAKFM
50 AIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFCGKN------PLGDDE-SSTVSTSKT
51 EVSS------VSPA----------------------------------------------
52 -----------------------------------------
53 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
54 ------------------------------------------------------------
55 ---------MNGTE--GNNFYVP----LSNRTGLVRSPFEYPQYYLAEPWQ---------
56 FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTF
57 YTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSST
58 HASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESYV
59 LYMFICHFILPVTIIFFTYGRLVCTV----------------------------------
60 ------------------------------------------------------------
61 -------------------KAAAAQQQ-----------------------------DSAS
62 TQKA----------EREVTKMVILMVLGFLVAWTPYATVAAWIFF---NKGAA-FSAQFM
63 AIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFCGKN------PLGDEE-SSTVSTSKT
64 EVSS------VSPA----------------------------------------------
65 -----------------------------------------
66 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
67 ------------------------------------------------------------
68 ---------MKQVPEFHEDFYIPIPLDINNLS--AYSPFLVPQDHLGNQGI---------
69 FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSF
70 YSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTP
71 HAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESYV
72 MFLFCFCFAVPFGTIVFCYGQLLITL----------------------------------
73 ------------------------------------------------------------
74 -------------------KLAAKAQA-----------------------------DSAS
75 TQKA----------EREVTKMVVVMVLGFLVCWAPYASFSLWIVS---HRGEE-FDLRMA
76 TIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVCGKN-------IEEDE--ASTSSQVT
77 QVSS------VAPEK---------------------------------------------
78 -----------------------------------------
79 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
80 ------------------------------------------------------------
81 ---------MRKMS--EEEFYL-----FKNISSV--GPWDGPQYHIAPVWA---------
82 FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVF
83 VASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSK
84 HALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESYT
85 WFLFIFCFIVPLSLICFSYTQLLRAL----------------------------------
86 ------------------------------------------------------------
87 -------------------KAVAAQQQ-----------------------------ESAT
88 TQKA----------EREVSRMVVVMVGSFCVCYVPYAAFAMYMVN---NRNHG-LDLRLV
89 TIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVCGKA-------MTDES--DTCSSQKT
90 EVSTVS-STQVGPN----------------------------------------------
91 -----------------------------------------
92 > 8=opsin, greensensitive human (fragment) S07060
93 ------------------------------------------------------------
94 ------------------------------------------------------------
95 ----------------------------------------------DLAETVIA-STISI
96 VNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAK
97 LAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYM
98 IVLMVTCCITPLSIIVLCYLQVWLAI----------------------------------
99 ------------------------------------------------------------
100 -------------------RAVAKQQK-----------------------------ESES
101 TQKA----------EKEVTRMVVVMVLAFC------------------------------
102 ------------------------------------------------------------
103 ------------------------------------------------------------
104 -----------------------------------------
105 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
106 ----------------------------------------------------------MA
107 QQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNS-TRGPFEGPNYHIAPRWV---------
108 YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISV
109 VNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAK
110 LAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYM
111 IVLMVTCCITPLSIIVLCYLQVWLAI----------------------------------
112 ------------------------------------------------------------
113 -------------------RAVAKQQK-----------------------------ESES
114 TQKA----------EKEVTRMVVVMVLAFCFCWGPYAFFACFAAA---NPGYP-FHPLMA
115 ALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF-----------GKKVDDGSELSSASKT
116 EVSSV---SSVSPA----------------------------------------------
117 -----------------------------------------
118 > 10== Z68193 1 human Red Opsin <>[]
119 ----------------------------------------------------------MA
120 QQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNS-TRGPFEGPNYHIAPRWV---------
121 YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISI
122 VNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAK
123 LAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYM
124 IVLMVTCCIIPLAIIMLCYLQVWLAI----------------------------------
125 ------------------------------------------------------------
126 -------------------RAVAKQQK-----------------------------ESES
127 TQKA----------EKEVTRMVVVMIFAYCVCWGPYTFFACFAAA---NPGYA-FHPLMA
128 ALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF-----------GKKVDDGSELSSASKT
129 EVSSV---SSVSPA----------------------------------------------
130 -----------------------------------------
131 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
132 ----------------------------------------------------------MT
133 EAWNVAVFAARRSRD-DDDTTRGSVFTYTNTNN-TRGPFEGPNYHIAPRWV---------
134 YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISV
135 FNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSK
136 LAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSFM
137 LTLMITCCFLPLFIIIVCYLQVWMAI----------------------------------
138 ------------------------------------------------------------
139 -------------------RAVAAQQK-----------------------------ESES
140 TQKA----------EREVSRMVVVMIVAFCICWGPYASFVSFAAA---NPGYA-FHPLAA
141 ALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF-----------GKKVDDGSEASTTSRT
142 EVSSVS-NSSVAPA----------------------------------------------
143 -----------------------------------------
144 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
145 -----------------------------------------------------------M
146 AAWEAAFAARRRHE--EEDTTRDSVFTYTNSNN-TRGPFEGPNYHIAPRWV---------
147 YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISV
148 INQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGK
149 LAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSYM
150 VVLMVTCCFFPLAIIILCYLQVWLAI----------------------------------
151 ------------------------------------------------------------
152 -------------------RAVAAQQK-----------------------------ESES
153 TQKA----------EKEVSRMVVVMIVAYCFCWGPYTFFACFAAA---NPGYA-FHPLAA
154 ALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF-----------GKKVDDGSEVST-SRT
155 EVSSVS-NSSVSPA----------------------------------------------
156 -----------------------------------------
157 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
158 ------------------------------------------------------------
159 ----------------------------MSSNSSQAPPNGTPGPFDGPQWP--YQAPQST
160 YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSL
161 SNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRR
162 HAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGS--NNNSYI
163 LSLFVTCFVLPLSLILFSYTNLLLTL----------------------------------
164 ------------------------------------------------------------
165 -------------------RAAAAQQK-----------------------------EADT
166 TQRA----------EREVTRMVIVMVMAFLLCWLPYSTFALVVAT---HKGII-IQPVLA
167 SLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGYQ------PQRTGKASPGTPGPHA
168 DVTAAGLRNKVMPAHPV-------------------------------------------
169 -----------------------------------------
170 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
171 ------------------------------------------------------MESGNV
172 SSSLFGNVSTALRPEARLSAE--------TRLLGWNVPPEELR-HIPEHWLTYPEPPESM
173 NYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFI
174 YNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHG
175 KAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFV
176 ACIFFFSFVCPTTMITYYYSQIVGHVFSH-------------------------------
177 ------------------------------------------------------------
178 ------------------EKALRDQAKKMNVESLRS-------------------NVDKN
179 KETA----------EIRIAKAAITICFLFFCSWTPYGVMSLIGAF---GDKTL-LTPGAT
180 MIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL---------NEKAPESSAVAST
181 STTQEPQQTTAA------------------------------------------------
182 -----------------------------------------
183 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
184 ------------------------------------------------------MEYHNV
185 S-SVLGNVSSVLRPDARLSAE--------SRLLGWNVPPDELR-HIPEHWLIYPEPPESM
186 NYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFI
187 YNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHG
188 KAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFV
189 ACIFFFSFVCPTTMITYYYSQIVGHVFSH-------------------------------
190 ------------------------------------------------------------
191 ------------------EKALRDQAKKMNVDSLRS-------------------NVDKS
192 KEAA----------EIRIAKAAITICFLFFASWTPYGVMSLIGAF---GDKTL-LTPGAT
193 MIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI---------SEKAPESRAAIST
194 STTQEQQQTTAA------------------------------------------------
195 -----------------------------------------
196 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
197 ------------------------------------------------------ME----
198 --PLCNASEPPLRPEARSSGNGD------LQFLGWNVPPDQIQ-YIPEHWLTQLEPPASM
199 HYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF-
200 -NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFT
201 KAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFV
202 GTIFFFSFVCPTLMILYYYSQIVGHVFSH-------------------------------
203 ------------------------------------------------------------
204 ------------------EKALREQAKKMNVESLRS-------------------NVDKS
205 KETA----------EIRIAKAAITICFLFFVSWTPYGVMSLIGAF---GDKSL-LTQGAT
206 MIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV---------NEKSGEISSAQST
207 TTQEQ-QQTTAA------------------------------------------------
208 -----------------------------------------
209 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
210 ------------------------------------------------------MD----
211 --ALCNASEPPLRPEARMSSGSDE-----LQFLGWNVPPDQIQ-YIPEHWLTQLEPPASM
212 HYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFI
213 YNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFT
214 KAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFV
215 GTIFLFSFVVPTLMILYYYSQIVGHVFNH-------------------------------
216 ------------------------------------------------------------
217 ------------------EKALREQAKKMNVESLRS-------------------NVDKS
218 KETA----------EIRIAKAAITICFLFFVSWTPYGVMSLIGAF---GDKSL-LTPGAT
219 MIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV---------NEKSGEASSAQST
220 TTQEQTQQTSAA------------------------------------------------
221 -----------------------------------------
222 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
223 ------------------------------------------------------------
224 ---MTNATGPQMAYYGAASMDFGYPE---GVSIVDFVRPEIKP-YVHQHWYNYPPVNPMW
225 HYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFT
226 YNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTG
227 KAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNTFSYN
228 IFIFVFDYFLPAAIIVFSYVFIVKAIFAH-------------------------------
229 ------------------------------------------------------------
230 ------------------EAAMRAQAKKMNVSTLRS--------------------NEAD
231 AQRA----------EIRIAKTALVNVSLWFICWTPYALISLKGVM---GDTSG-ITPLVS
232 TLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV------HETETKSNDDSQSNST
233 VAQDKA------------------------------------------------------
234 -----------------------------------------
235 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
236 ------------------------------------------------------------
237 ---MANVTGPQMAFYGSGAATFGYPE---GMTVADFVPDRVKH-MVLDHWYNYPPVNPMW
238 HYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFC
239 YNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQG
240 KATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNTITYN
241 ICIFIFDFFLPASVIVFSYVFIVKAIFAH-------------------------------
242 ------------------------------------------------------------
243 ------------------EAAMRAQAKKMNVTNLRS--------------------NEAE
244 TQRA----------EIRIAKTALVNVSLWFICWTPYAAITIQGLL---GNAEG-ITPLLT
245 TLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV------HEKDPNDVEENQSSNT
246 QTQEKS------------------------------------------------------
247 -----------------------------------------
248 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
249 ---------------------------------------------------------MES
250 FAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH-LISPYWNQFPAMDPIW
251 AKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
252 INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIP
253 LALGKM---------------------------YVPEGNLTSCGIDYLE--RDWNPRSYL
254 IFYSIFVYYIPLFLICYSYWFIIAAVSAH-------------------------------
255 ------------------------------------------------------------
256 ------------------EKAMREQAKKMNVKSLRS--------------------SEDA
257 EKSA----------EGKLAKVALVTITLWFMAWTPYLVINCMGLF---KF-EG-LTPLNT
258 IWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDGK-SSDAQSQA
259 TASEAESKA---------------------------------------------------
260 -----------------------------------------
261 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
262 ---------------------------------------------------------MES
263 FAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH-LISPYWNQFPAMDPIW
264 AKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
265 INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIP
266 LALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYL
267 IFYSIFVYYIPLFLICYSYWFIIAAVSAH-------------------------------
268 ------------------------------------------------------------
269 ------------------EKAMREQAKKMNVKSLRS--------------------SEDA
270 EKSA----------EGKLAKVALVTITLWFMAWTPYLVINCMGLF---KF-EG-LTPLNT
271 IWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDGK-SSDAQSQA
272 TASEAESKA---------------------------------------------------
273 -----------------------------------------
274 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
275 ---------------------------------------------------------MDS
276 FAAVATQLGPQFA-----APS--------NGSVVDKVTPDMAH-LISPYWDQFPAMDPIW
277 AKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
278 INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIP
279 LALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYL
280 IFYSIFVYYIPLFLICYSYWFIIAAVSAH-------------------------------
281 ------------------------------------------------------------
282 ------------------EKAMREQAKKMNVKSLRS--------------------SEDA
283 DKSA----------EGKLAKVALVTISLWFMAWTPYLVINCMGLF---KF-EG-LTPLNT
284 IWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDGK-SSEAQSQA
285 TTSEAESKA---------------------------------------------------
286 -----------------------------------------
287 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
288 ----------------------------------------------------MERSHLPE
289 TPFDLAHSGPRFQ-----AQSSG------NGSVLDNVLPDMAH-LVNPYWSRFAPMDPMM
290 SKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMI
291 INFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIK
292 TSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNPRSYL
293 ITYSLFVYYTPLFLICYSYWFIIAAVAAH-------------------------------
294 ------------------------------------------------------------
295 ------------------EKAMREQAKKMNVKSLRS--------------------SEDC
296 DKSA----------EGKLAKVALTTISLWFMAWTPYLVICYFGLF---KI-DG-LTPLTT
297 IWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF------GNTDEPKPDAPASDTE
298 TTSEADSKA---------------------------------------------------
299 -----------------------------------------
300 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
301 ----------------------------------------------------MERSLLPE
302 PPLAMALLGPRFE-----AQTGG------NRSVLDNVLPDMAP-LVNPHWSRFAPMDPTM
303 SKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMI
304 INFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIK
305 TSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNPRSYL
306 ITYSLFVYYTPLFMICYSYWFIIATVAAH-------------------------------
307 ------------------------------------------------------------
308 ------------------EKAMRDQAKKMNVKSLRS--------------------SEDC
309 DKSA----------ENKLAKVALTTISLWFMAWTPYLIICYFGLF---KI-DG-LTPLTT
310 IWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC------GTTDEPKPDAPPSDTE
311 TTSEAESKD---------------------------------------------------
312 -----------------------------------------
313 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
314 ------------------------------------------------------------
315 ---MIAVSGPSYE-----AFSYGGQARFNNQTVVDKVPPDMLH-LIDANWYQYPPLNPMW
316 HGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMV
317 INCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSIN
318 GALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLSASYL
319 VCYGIWVYFVPLFLIIYSYWFIIQAVAAH-------------------------------
320 ------------------------------------------------------------
321 ------------------EKNMREQAKKMNVASLRS--------------------SENQ
322 NTSA----------ECKLAKVALMTISLWFMAWTPYLVINFSGIF---NL-VK-ISPLFT
323 IWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC-------AAEPSSDAVSTTSGT
324 TTVTDNEKSNA-------------------------------------------------
325 -----------------------------------------
326 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
327 ------------------------------------------------------------
328 -----MANQLSYS-----SLGWPYQP---NASVVDTMPKEMLY-MIHEHWYAFPPMNPLW
329 YSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMT
330 SNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHK
331 KATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSSASYV
332 VIYGLAVYFLPLITMIYCYFFIVHAVAEH-------------------------------
333 ------------------------------------------------------------
334 ------------------EKQLREQAKKMNVASLRA-------------------NADQQ
335 KQSA----------ECRLAKVAMMTVGLWFMAWTPYLIISWAGVF---SSGTR-LTPLAT
336 IWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC------GSGESGSDVKSEASAT
337 TTMEEKPKIPEA------------------------------------------------
338 -----------------------------------------
339 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
340 ------------------------------------------------------------
341 ----------MVESTTLVNQTWWY-----NPTVD-----------IHPHWAKFDPIPDAV
342 YYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKT
343 ISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHR
344 RAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPSTRSFI
345 LCMYFCGFMLPIIIIAFCYFNIVMSVSNH-------------------------------
346 ------------------------------------------------------------
347 ------------------EKEMAAMAKRLNAKELR---------------------KAQA
348 GASA----------EMKLAKISMVIITQFMLSWSPYAIIALLAQF---GPAEW-VTPYAA
349 ELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECEDANDAEEEVVAS
350 ER--GGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQGAYPPPQGYP
351 PQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
352 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
353 ------------------------------------------------------------
354 -----------MGRDLRDNETWWY-----NPSIV-----------VHPHWREFDQVPDAV
355 YYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMT
356 ISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHR
357 RAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTTRSNI
358 LCMFILGFFGPILIIFFCYFNIVMSVSNH-------------------------------
359 ------------------------------------------------------------
360 ------------------EKEMAAMAKRLNAKELR---------------------KAQA
361 GANA----------EMRLAKISIVIVSQFLLSWSPYAVVALLAQF---GPLEW-VTPYAA
362 QLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIPAG
363 ESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQGY--PPQGYP
364 PQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
365 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
366 ---------MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLS-
367 --EVTASPAPTWDAPPDNASGCGEQINYGRVE----------------------------
368 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
369 VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
370 CMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYT
371 IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIAL-----------
372 ------------------------------------------------------------
373 ------------------NGIVKLQKEVEECANLSR-------------------LLKHE
374 RKNI-----SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-IPLWVE
375 RTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPE
376 RPEFVLQNADYCRKKGHDS-----------------------------------------
377 -----------------------------------------
378 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
379 -----------------------------------------------------MPHLLSG
380 FLEVTASPAPTWDAPPDNVSGCGEQINYGRVE----------------------------
381 KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
382 VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
383 CMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYT
384 IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISL-----------
385 ------------------------------------------------------------
386 ------------------NGVVKLQKEVEECANLSR-------------------LLKHE
387 RKNI-----SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-IPLWVE
388 RTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYRNINRKLSAAGMHEALKLAERPE
389 RSEFVLQNSDHCGKKGHDT-----------------------------------------
390 -----------------------------------------
391 > 31=p A47425 serotonin receptor 5HT-7 - rat
392 -----------------------------------------------------MPHLLSG
393 FLEVTASPAPTWDAPPDNVSGCGEQINYGRVE----------------------------
394 KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
395 VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
396 CMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYT
397 IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISL-----------
398 ------------------------------------------------------------
399 ------------------NGVVKLQKEVEECANLSR-------------------LLKHE
400 RKNI-----SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-IPLWVE
401 RTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPE
402 RSEFVLQNSDHCGKKGHDT-----------------------------------------
403 -----------------------------------------
404 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
405 MDVLSPGQGN---------------------------------------NTTSPPAPFET
406 GGNTTGISDVTVSY----------------------------------------------
407 QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAA
408 LYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPR
409 RAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH----------GYT
410 IYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------------------
411 -----------TVKKVEKTGADTRHGASPAPQPKKS----------VNGESGSRNWRLGV
412 ESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCA--PASFERKN
413 ERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF---CESSCHMPTLLG
414 AIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ--------------------
415 ------------------------------------------------------------
416 -----------------------------------------
417 > 33=p A35181 serotonin receptor class 1A - rat
418 MDVFSFGQGN---------------------------------------NTTASQEPFGT
419 GGNVTSISDVTFSY----------------------------------------------
420 QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAA
421 LYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPR
422 RAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH----------GYT
423 IYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------------------
424 -----------TVRKVEKKGAGTSLGTSSAPPPKKS----------LNGQPGSGDWRRCA
425 ENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYA--PACLERKN
426 ERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF---CESSCHMPALLG
427 AIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR--------------------
428 ------------------------------------------------------------
429 -----------------------------------------
430 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
431 MANFTFGDLALDVARMGGLASTPSGLR----------------------STGLTTPGLSP
432 TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATN----MTDDRYWSLTVYSHEH
433 LVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSV
434 VSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSAR
435 RILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYT
436 IFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVV
437 SDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQ
438 IQIETAEAFANGCA----EEASIAMLERQ-CNNGKK-------------------ISSND
439 TPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF---VDPEG-IPPFAR
440 SFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR------------------
441 ------------------------------------------------------------
442 -----------------------------------------
443 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
444 MANFTFGDLALDVARMGGLASTPSGLR----------------------STGLTTPGLSP
445 TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATN----MTDDRYWSLTVYSHEH
446 LVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSV
447 VSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSAR
448 RILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYT
449 IFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVV
450 SDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQ
451 IQIETAEAFANGCA----EEASIAMLERQ-CNNGKK-------------------ISSND
452 TPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF---VDPEG-IPPFAR
453 SFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR------------------
454 ------------------------------------------------------------
455 -----------------------------------------
456 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
457 ---------------------------MEGAEGQEELDWEALYLRLPLQNCSWNSTGWEP
458 NWNVTVVPNTTWWQ--------------------ASAPFDTPAALVR-------------
459 AAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGA
460 VYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAK
461 RVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQ
462 IFATASSFYVPVLIILILYWRIYQTARKRIRR----------------------------
463 -----------------RRGATARGGVGPPPVPAGGALVA------GGGSGGIAAAVVAV
464 IGRPLPTISETTTTGFTNVSSNNTSPEKQSCANGLEADPPTTGYGAVAAAYYPSLVRRKP
465 KEAA------DSKRERKAAKTLAIITGAFVACWLPFFVLAILVPT---CDCE--VSPVLT
466 SLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRVRRRRAPQ---------------
467 ------------------------------------------------------------
468 -----------------------------------------
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