1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 MN--------------------GTE--GDNFYVPFSNKTG--LARSP-------------
3 --------------------YEYPQY-YLAEPW---------KYSA-----LAAYMFFLI
4 LVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYFV--
5 FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNTHAIMGVAFTWIM
6 ALAC-AAPPLV-GWS-----RYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPF
7 VIIFFCYGRLLCTVKEAAAAQQESA-----------------------------------
8 ------------------------------------------------------------
9 ----------------------------------------------STQKAEKEVTRMVV
10 LMVIGFLVCWVPYASVAFYIFT--HQGSD-FGATFMTLPAFFAKSSALYNPVIYILMNKQ
11 FRNCMITTL-----CCGKNPLGDDE-SG-ASTSKTEVS----------------------
12 ------------------------------------------------------------
13 ----------------SVS-TSPVSPA---
14 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
15 MN--------------------GTE--GPNFYVPFSNITG--VVRSP-------------
16 --------------------FEQPQY-YLAEPW---------QFSM-----LAAYMFLLI
17 VLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYFV--
18 FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGENHAIMGVAFTWVM
19 ALAC-AAPPLV-GWS-----RYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPM
20 IVIFFCYGQLVFTVKEAAAQQQESA-----------------------------------
21 ------------------------------------------------------------
22 ----------------------------------------------TTQKAEKEVTRMVI
23 IMVIFFLICWLPYASVAMYIFT--HQGSN-FGPIFMTLPAFFAKTASIYNPIIYIMMNKQ
24 FRNCMLTSL-----CCGKNPLGDDE-AS-ATASKTETS----------------------
25 ------------------------------------------------------------
26 ----------------QVA-PA--------
27 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
28 MN--------------------GTE--GINFYVPMSNKTG--VVRSP-------------
29 --------------------FEYPQY-YLAEPW---------KYRL-----VCCYIFFLI
30 STGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYFV--
31 FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSATHAMMGIAFTWVM
32 AFSC-AAPPLF-GWS-----RYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPV
33 VVIFFSYGRLICKVREAAAQQQESA-----------------------------------
34 ------------------------------------------------------------
35 ----------------------------------------------TTQKAEKEVTRMVI
36 LMVLGFMLAWTPYAVVAFWIFT--NKGAD-FTATLMAVPAFFSKSSSLYNPIIYVLMNKQ
37 FRNCMITTI-----CCGKNPFGDEDVSSTVSQSKTEVS----------------------
38 ------------------------------------------------------------
39 ----------------SVS-SSQVSPA---
40 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
41 MN--------------------GTE--GKNFYVPMSNRTG--LVRSP-------------
42 --------------------FEYPQY-YLAEPW---------QFKI-----LALYLFFLM
43 SMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYFV--
44 LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSSHAFAGIAFTWVM
45 ALAC-AAPPLF-GWS-----RYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPV
46 AVIFFTYGRLVCTVKAAAAQQQDSA-----------------------------------
47 ------------------------------------------------------------
48 ----------------------------------------------STQKAEREVTKMVI
49 LMVFGFLIAWTPYATVAAWIFF--NKGAD-FSAKFMAIPAFFSKSSALYNPVIYVLLNKQ
50 FRNCMLTTI-----FCGKNPLGDDE-SSTVSTSKTEVS----------------------
51 ------------------------------------------------------------
52 ----------------SVS-PA--------
53 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
54 MN--------------------GTE--GNNFYVPLSNRTG--LVRSP-------------
55 --------------------FEYPQY-YLAEPW---------QFKL-----LAVYMFFLI
56 CLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYFA--
57 LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSTHASAGIAFTWVM
58 AMAC-AAPPLV-GWS-----RYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPV
59 TIIFFTYGRLVCTVKAAAAQQQDSA-----------------------------------
60 ------------------------------------------------------------
61 ----------------------------------------------STQKAEREVTKMVI
62 LMVLGFLVAWTPYATVAAWIFF--NKGAA-FSAQFMAIPAFFSKTSALYNPVIYVLLNKQ
63 FRSCMLTTL-----FCGKNPLGDEE-SSTVSTSKTEVS----------------------
64 ------------------------------------------------------------
65 ----------------SVS-PA--------
66 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
67 MK--------------------QVPEFHEDFYIPIPLDINNLSAYSP-------------
68 --------------------FLVPQD-HLGNQG---------IFMA-----MSVFMFFIF
69 IGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYFI--
70 FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTPHAIAGCILPWIS
71 ALAA-SLPPLF-GWS-----RYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPF
72 GTIVFCYGQLLITLKLAAKAQADSA-----------------------------------
73 ------------------------------------------------------------
74 ----------------------------------------------STQKAEREVTKMVV
75 VMVLGFLVCWAPYASFSLWIVS--HRGEE-FDLRMATIPSCLSKASTVYNPVIYVLMNKQ
76 FRSCMM-KM-----VCGKN-IEEDE-AS-TSSQVTQVS----------------------
77 ------------------------------------------------------------
78 ----------------SVA-PEK-------
79 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
80 MR--------------------KMS--EEEFYL-----FKNISSVGP-------------
81 --------------------WDGPQY-HIAPVW---------AFYL-----QAAFMGTVF
82 LIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYFV--
83 FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSKHALTVVLATWTI
84 GIGV-SIPPFF-GWS-----RFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPL
85 SLICFSYTQLLRALKAVAAQQQESA-----------------------------------
86 ------------------------------------------------------------
87 ----------------------------------------------TTQKAEREVSRMVV
88 VMVGSFCVCYVPYAAFAMYMVN--NRNHG-LDLRLVTIPSFFSKSACIYNPIIYCFMNKQ
89 FQACIM-KM-----VCGKA-MTDES-DT-CSSQKTEVS----------------------
90 ------------------------------------------------------------
91 ----------------TVS-STQVGPN---
92 > 8=opsin, greensensitive human (fragment) S07060
93 ------------------------------------------------------------
94 ------------------------------------------------------------
95 ----------------------------------DLAETVIA-STISIVNQVS-GYFV--
96 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIW
97 AAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPL
98 SIIVLCYLQVWLAIRAVAKQQKESE-----------------------------------
99 ------------------------------------------------------------
100 ----------------------------------------------STQKAEKEVTRMVV
101 VMVLAFC-----------------------------------------------------
102 ------------------------------------------------------------
103 ------------------------------------------------------------
104 ------------------------------
105 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
106 MAQQWS-LQRLAGRHPQDSYEDSTQ--SSIFTY-----TNSNSTRGP-------------
107 --------------------FEGPNY-HIAPRW---------VYHL-----TSVWMIFVV
108 IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYFV--
109 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAKLAIVGIAFSWIW
110 AAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPL
111 SIIVLCYLQVWLAIRAVAKQQKESE-----------------------------------
112 ------------------------------------------------------------
113 ----------------------------------------------STQKAEKEVTRMVV
114 VMVLAFCFCWGPYAFFACFAAA--NPGYP-FHPLMAALPAFFAKSATIYNPVIYVFMNRQ
115 FRNCILQLF----------GKKVDDGSELSSASKTEVS----------------------
116 ------------------------------------------------------------
117 ----------------SV---SSVSPA---
118 > 10== Z68193 1 human Red Opsin <>[]
119 MAQQWS-LQRLAGRHPQDSYEDSTQ--SSIFTY-----TNSNSTRGP-------------
120 --------------------FEGPNY-HIAPRW---------VYHL-----TSVWMIFVV
121 TASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYFV--
122 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIW
123 SAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPL
124 AIIMLCYLQVWLAIRAVAKQQKESE-----------------------------------
125 ------------------------------------------------------------
126 ----------------------------------------------STQKAEKEVTRMVV
127 VMIFAYCVCWGPYTFFACFAAA--NPGYA-FHPLMAALPAYFAKSATIYNPVIYVFMNRQ
128 FRNCILQLF----------GKKVDDGSELSSASKTEVS----------------------
129 ------------------------------------------------------------
130 ----------------SV---SSVSPA---
131 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
132 MTEAWNVAVFAARRSRDD--DDTTR--GSVFTY-----TNTNNTRGP-------------
133 --------------------FEGPNY-HIAPRW---------VYNL-----VSFFMIIVV
134 IASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYFI--
135 LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSKLAIIGIVFSWVW
136 AWGW-SAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPL
137 FIIIVCYLQVWMAIRAVAAQQKESE-----------------------------------
138 ------------------------------------------------------------
139 ----------------------------------------------STQKAEREVSRMVV
140 VMIVAFCICWGPYASFVSFAAA--NPGYA-FHPLAAALPAYFAKSATIYNPVIYVFMNRQ
141 FRNCIMQLF----------GKKVDDGSEASTTSRTEVS----------------------
142 ------------------------------------------------------------
143 ----------------SVS-NSSVAPA---
144 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
145 MA-AWE-AAFAARRRHEE--EDTTR--DSVFTY-----TNSNNTRGP-------------
146 --------------------FEGPNY-HIAPRW---------VYNL-----TSVWMIFVV
147 AASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYFI--
148 LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGKLAVAGILFSWLW
149 SCAW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPL
150 AIIILCYLQVWLAIRAVAAQQKESE-----------------------------------
151 ------------------------------------------------------------
152 ----------------------------------------------STQKAEKEVSRMVV
153 VMIVAYCFCWGPYTFFACFAAA--NPGYA-FHPLAAALPAYFAKSATIYNPIIYVFMNRQ
154 FRNCILQLF----------GKKVDDGSEVST-SRTEVS----------------------
155 ------------------------------------------------------------
156 ----------------SVS-NSSVSPA---
157 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
158 MS--------------------------SNSSQ-----APPNGTPGP-------------
159 --------------------FDGPQWPYQAPQS---------TYVG-----VAVLMGTVV
160 ACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFFV--
161 FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRRHAVSGCAFTWGW
162 ALLW-SAPPLL-GWS-----SYVPEGLRTSCGPNWYTGGSN--NNSYILSLFVTCFVLPL
163 SLILFSYTNLLLTLRAAAAQQKEAD-----------------------------------
164 ------------------------------------------------------------
165 ----------------------------------------------TTQRAEREVTRMVI
166 VMVMAFLLCWLPYSTFALVVAT--HKGII-IQPVLASLPSYFSKTATVYNPIIYVFMNKQ
167 FQSCLLEML-----CCGYQPQRTGKASPGTPGPHADVT----------------------
168 ------------------------------------------------------------
169 ----------------AAGLRNKVMPAHPV
170 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
171 MESGNVSSSLFGNVSTALRPE----ARLSA---E---TRLLGWNVPP-------------
172 --------------------EELR---HIPEHWLTYPEPPESMNYL-----LGTLYIFFT
173 LMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSFH-QGYA--
174 LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMY
175 ATPW-VVACYTETWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPT
176 TMITYYYSQIVGHVFSHEKALRDQAKKMNVESLR--------------------------
177 ------------------------------------------------------------
178 -----------------------------------------SNVDKNKETAEIRIAKAAI
179 TICFLFFCSWTPYGVMSLIGAF--GDKTL-LTPGATMIPACACKMVACIDPFVYAISHPR
180 YRMELQKRCPWL--ALNEKAPESSAVASTST-TQEPQQT---------------------
181 ------------------------------------------------------------
182 ----------------TAA-----------
183 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
184 MEYHNVSSVL-GNVSSVLRPD----ARLSA---E---SRLLGWNVPP-------------
185 --------------------DELR---HIPEHWLIYPEPPESMNYL-----LGTLYIFFT
186 VISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSFH-QGYA--
187 LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLY
188 ATPW-VVACYTESWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPT
189 TMITYYYSQIVGHVFSHEKALRDQAKKMNVDSLR--------------------------
190 ------------------------------------------------------------
191 -----------------------------------------SNVDKSKEAAEIRIAKAAI
192 TICFLFFASWTPYGVMSLIGAF--GDKTL-LTPGATMIPACTCKMVACIDPFVYAISHPR
193 YRMELQKRCPWL--AISEKAPESRAAISTST-TQEQQQT---------------------
194 ------------------------------------------------------------
195 ----------------TAA-----------
196 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
197 ME------PLCNASEPPLRPE----AR-SSGNGD---LQFLGWNVPP-------------
198 --------------------DQIQ---YIPEHWLTQLEPPASMHYM-----LGVFYIFLF
199 CASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSFH-RGFAIY
200 LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLY
201 CTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFFFSFVCPT
202 LMILYYYSQIVGHVFSHEKALREQAKKMNVESLR--------------------------
203 ------------------------------------------------------------
204 -----------------------------------------SNVDKSKETAEIRIAKAAI
205 TICFLFFVSWTPYGVMSLIGAF--GDKSL-LTQGATMIPACTCKLVACIDPFVYAISHPR
206 YRLELQKRCPWL--GVNEKSGEISSAQSTTT-QEQQQTT---------------------
207 ------------------------------------------------------------
208 ----------------AA------------
209 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
210 MD------ALCNASEPPLRPE----ARMSSGSDE---LQFLGWNVPP-------------
211 --------------------DQIQ---YIPEHWLTQLEPPASMHYM-----LGVFYIFLF
212 FASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSFH-RGFA--
213 LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLY
214 CTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFLFSFVVPT
215 LMILYYYSQIVGHVFNHEKALREQAKKMNVESLR--------------------------
216 ------------------------------------------------------------
217 -----------------------------------------SNVDKSKETAEIRIAKAAI
218 TICFLFFVSWTPYGVMSLIGAF--GDKSL-LTPGATMIPACTCKLVACIEPFVYAISHPR
219 YRMELQKRCPWL--GVNEKSGEASSAQSTTT-QEQTQQT---------------------
220 ------------------------------------------------------------
221 ----------------SAA-----------
222 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
223 M-----------TNATGPQMAYYGAASMDFGYPE---GVSIVDFVRP-------------
224 --------------------EIKP---YVHQHWYNYPPVNPMWHYL-----LGVIYLFLG
225 TVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVWM--
226 FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTGKAVVFALISWVI
227 AIGC-ALPPFF-GWG-----NYILEGILDSCSYDYLTQD--FNTFSYNIFIFVFDYFLPA
228 AIIVFSYVFIVKAIFAHEAAMRAQAKKMNVSTLR--------------------------
229 ------------------------------------------------------------
230 -----------------------------------------S-NEADAQRAEIRIAKTAL
231 VNVSLWFICWTPYALISLKGVM--GDTSG-ITPLVSTLPALLAKSCSCYNPFVYAISHPK
232 YRLAITQHLPWF--CVHETETKSNDDSQSNS-TVAQDK----------------------
233 ------------------------------------------------------------
234 ------------------A-----------
235 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
236 M-----------ANVTGPQMAFYGSGAATFGYPE---GMTVADFVPD-------------
237 --------------------RVKH---MVLDHWYNYPPVNPMWHYL-----LGVVYLFLG
238 VISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRWM--
239 FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQGKATFMCGLAWVI
240 SVGW-SLPPFF-GWG-----SYTLEGILDSCSYDYFTRD--MNTITYNICIFIFDFFLPA
241 SVIVFSYVFIVKAIFAHEAAMRAQAKKMNVTNLR--------------------------
242 ------------------------------------------------------------
243 -----------------------------------------S-NEAETQRAEIRIAKTAL
244 VNVSLWFICWTPYAAITIQGLL--GNAEG-ITPLLTTLPALLAKSCSCYNPFVYAISHPK
245 FRLAITQHLPWF--CVHEKDPNDVEENQSSN-TQTQEK----------------------
246 ------------------------------------------------------------
247 ------------------S-----------
248 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
249 ME-----SFAVAAAQLGPHFA-----PLS--------NGSVVDKVTP-------------
250 --------------------DMAH---LISPYWNQFPAMDPIWAKI-----LTAYMIMIG
251 MISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--
252 LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKM------
253 ---------------------YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPL
254 FLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR--------------------------
255 ------------------------------------------------------------
256 -----------------------------------------S-SEDAEKSAEGKLAKVAL
257 VTITLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGACFAKSAACYNPIVYGISHPK
258 YRLALKEKCPCC--VFGKVDDGKSSDAQSQA-TASEAE----------------------
259 ------------------------------------------------------------
260 ----------------SKA-----------
261 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
262 ME-----SFAVAAAQLGPHFA-----PLS--------NGSVVDKVTP-------------
263 --------------------DMAH---LISPYWNQFPAMDPIWAKI-----LTAYMIMIG
264 MISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--
265 LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFM
266 SSIW-CLAPAF-GWS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPL
267 FLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR--------------------------
268 ------------------------------------------------------------
269 -----------------------------------------S-SEDAEKSAEGKLAKVAL
270 VTITLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGACFAKSAACYNPIVYGISHPK
271 YRLALKEKCPCC--VFGKVDDGKSSDAQSQA-TASEAE----------------------
272 ------------------------------------------------------------
273 ----------------SKA-----------
274 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
275 MD-----SFAAVATQLGPQFA-----APS--------NGSVVDKVTP-------------
276 --------------------DMAH---LISPYWDQFPAMDPIWAKI-----LTAYMIIIG
277 MISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--
278 LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFM
279 STIWCCLAPVF-GWS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPL
280 FLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR--------------------------
281 ------------------------------------------------------------
282 -----------------------------------------S-SEDADKSAEGKLAKVAL
283 VTISLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGACFAKSAACYNPIVYGISHPK
284 YRLALKEKCPCC--VFGKVDDGKSSEAQSQA-TTSEAE----------------------
285 ------------------------------------------------------------
286 ----------------SKA-----------
287 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
288 MERSHLPETPFDLAHSGPRFQ-----AQSSG------NGSVLDNVLP-------------
289 --------------------DMAH---LVNPYWSRFAPMDPMMSKI-----LGLFTLAIM
290 IISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--
291 LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKILFIWMM
292 AVFW-TVMPLI-GWS-----AYVPEGNLTACSIDYMTRM--WNPRSYLITYSLFVYYTPL
293 FLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLR--------------------------
294 ------------------------------------------------------------
295 -----------------------------------------S-SEDCDKSAEGKLAKVAL
296 TTISLWFMAWTPYLVICYFGLF--KI-DG-LTPLTTIWGATFAKTSAVYNPIVYGISHPK
297 YRIVLKEKCPMC--VFGNTDEPKPDAPASDTETTSEAD----------------------
298 ------------------------------------------------------------
299 ----------------SKA-----------
300 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
301 MERSLLPEPPLAMALLGPRFE-----AQTGG------NRSVLDNVLP-------------
302 --------------------DMAP---LVNPHWSRFAPMDPTMSKI-----LGLFTLVIL
303 IISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--
304 LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKIAFIWMM
305 AVFW-TIMPLI-GWS-----SYVPEGNLTACSIDYMTRQ--WNPRSYLITYSLFVYYTPL
306 FMICYSYWFIIATVAAHEKAMRDQAKKMNVKSLR--------------------------
307 ------------------------------------------------------------
308 -----------------------------------------S-SEDCDKSAENKLAKVAL
309 TTISLWFMAWTPYLIICYFGLF--KI-DG-LTPLTTIWGATFAKTSAVYNPIVYGISHPN
310 DRLVLKEKCPMC--VCGTTDEPKPDAPPSDTETTSEAE----------------------
311 ------------------------------------------------------------
312 ----------------SKD-----------
313 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
314 M-----------IAVSGPSYE-----AFSYGGQARFNNQTVVDKVPP-------------
315 --------------------DMLH---LIDANWYQYPPLNPMWHGI-----LGFVIGMLG
316 FVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETWV--
317 LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSINGALIRIIAIWLF
318 SLGW-TIAPMF-GWN-----RYVPEGNMTACGTDYFNRG--LLSASYLVCYGIWVYFVPL
319 FLIIYSYWFIIQAVAAHEKNMREQAKKMNVASLR--------------------------
320 ------------------------------------------------------------
321 -----------------------------------------S-SENQNTSAECKLAKVAL
322 MTISLWFMAWTPYLVINFSGIF--NL-VK-ISPLFTIWGSLFAKANAVYNPIVYGISHPK
323 YRAALFAKFPSL--AC-AAEPSSDAVSTTSG-TTTVTDN---------------------
324 ------------------------------------------------------------
325 -------------EK-SNA-----------
326 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
327 M-------------ANQLSYS-----SLGWPYQP---NASVVDTMPK-------------
328 --------------------EMLY---MIHEHWYAFPPMNPLWYSI-----LGVAMIILG
329 IICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETWI--
330 LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHKKATLLLLFVWIW
331 SGGW-TILPFF-GWS-----RYVPEGNLTSCTVDYLTKD--WSSASYVVIYGLAVYFLPL
332 ITMIYCYFFIVHAVAEHEKQLREQAKKMNVASLR--------------------------
333 ------------------------------------------------------------
334 -----------------------------------------ANADQQKQSAECRLAKVAM
335 MTVGLWFMAWTPYLIISWAGVF--SSGTR-LTPLATIWGSVFAKANSCYNPIVYGISHPR
336 YKAALYQRFPSL--ACGSGESGSDVKSEASA-TTTMEEK---------------------
337 ------------------------------------------------------------
338 -------------PKIPEA-----------
339 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
340 M-------------VESTTLV-----NQTWWY-----NPTV-------------------
341 ---------------------------DIHPHWAKFDPIPDAVYYS-----VGIFIGVVG
342 IIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI--
343 FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMW
344 SIVW-SVGPVF-NWG-----AYVPEGILTSCSFDYLSTD--PSTRSFILCMYFCGFMLPI
345 IIIAFCYFNIVMSVSNHEKEMAAMAKRLNAKELR--------------------------
346 ------------------------------------------------------------
347 -----------------------------------------K-AQ-AGASAEMKLAKISM
348 VIITQFMLSWSPYAIIALLAQF--GPAEW-VTPYAAELPVLFAKASAIHNPIVYSVSHPK
349 FREAIQTTFPWLLTCCQFDEKECEDANDAEE-EVVASER--GGESRDAAQMKEMMAMMQK
350 MQAQQAAYQP---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQ
351 VEAPQGAPPQGVDNQAYQA-----------
352 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
353 M-------------GRDLR-D-----NETWWY-----NPSI-------------------
354 ---------------------------VVHPHWREFDQVPDAVYYS-----LGIFIGICG
355 IIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI--
356 FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLW
357 SVLW-AIGPIF-GWG-----AYTLEGVLCNCSFDYISRD--STTRSNILCMFILGFFGPI
358 LIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELR--------------------------
359 ------------------------------------------------------------
360 -----------------------------------------K-AQ-AGANAEMRLAKISI
361 VIVSQFLLSWSPYAVVALLAQF--GPLEW-VTPYAAQLPVMFAKASAIHNPMIYSVSHPK
362 FREAISQTFPWVLTCCQFDDKETEDDKDAET-EIPAGESSDAAPSADAAQMKEMMAMMQK
363 MQQQQAAYPPQGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP-
364 -----AAPPQGVDNQAYQA-----------
365 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
366 MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDG----GADPVAGSWAPHLLS---EVT
367 ASPAPTWDAPPDNA------SGCGE----------QINYGRVEKVV-----IGSILTLIT
368 LLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--
369 FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLL
370 SASI-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPM
371 SVMLFMYYQIYKAARKSAAKHKF--------------PGFPRVEPDSVIALNG-------
372 ---------------------------------------------IVKLQKE--------
373 ----------VEECAN------------------LSRLLKHERKNISIFKREQKAATTLG
374 IIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRD
375 LRTTYRSLL-----QCQYRNINRKLSAAGMHEALKLAERPERPEFVLQNADYCRKKGHDS
376 ------------------------------------------------------------
377 ------------------------------
378 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
379 M------------------------------------------------PHLLSGFLEVT
380 ASPAPTWDAPPDNV------SGCGE----------QINYGRVEKVV-----IGSILTLIT
381 LLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--
382 FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLL
383 SASI-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPM
384 SVMLFMYYQIYKAARKSAAKHKF--------------PGFPRVQPESVISLNG-------
385 ---------------------------------------------VVKLQKE--------
386 ----------VEECAN------------------LSRLLKHERKNISIFKREQKAATTLG
387 IIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRD
388 LRPTSRSLL-----QCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNSDHCGKKGHDT
389 ------------------------------------------------------------
390 ------------------------------
391 > 31=p A47425 serotonin receptor 5HT-7 - rat
392 M------------------------------------------------PHLLSGFLEVT
393 ASPAPTWDAPPDNV------SGCGE----------QINYGRVEKVV-----IGSILTLIT
394 LLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--
395 FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLL
396 SASI-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPM
397 SVMLFMYYQIYKAARKSAAKHKF--------------PGFPRVQPESVISLNG-------
398 ---------------------------------------------VVKLQKE--------
399 ----------VEECAN------------------LSRLLKHERKNISIFKREQKAATTLG
400 IIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRD
401 LRTTYRSLL-----QCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNSDHCGKKGHDT
402 ------------------------------------------------------------
403 ------------------------------
404 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
405 MDVLSPG-----------------------------------------------------
406 ---------QGNNT------TSPPAPFETGGNTTGISDVTVSYQVI-----TSLLLGTLI
407 FCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--
408 LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLI
409 GFLI-SIPPML-GWRTPEDRSDPD---ACTISKDH----------GYTIYSTFGAFYIPL
410 LLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKK-----SVNG--ESGSR
411 NWRLGVESKAGGALCANGAVRQGDDGAAL--EVIEVHRVGNSKEHLPLPSEAGPTPCAPA
412 S------------------FERKNERNA-------------EAKRKMALARERKTVKTLG
413 IIMGTFILCWLPFFIVALVLPF-CESSCH-MPTLLGAIINWLGYSNSLLNPVIYAYFNKD
414 FQNAFKKII-----KCKFCR--Q-------------------------------------
415 ------------------------------------------------------------
416 ------------------------------
417 > 33=p A35181 serotonin receptor class 1A - rat
418 MDVFSFG-----------------------------------------------------
419 ---------QGNNT------TASQEPFGTGGNVTSISDVTFSYQVI-----TSLLLGTLI
420 FCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--
421 LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLI
422 GFLI-SIPPML-GWRTPEDRSDPD---ACTISKDH----------GYTIYSTFGAFYIPL
423 LLMLVLYGRIFRAARFRIRKTVRKVEKKGAGTSLGTSSAPPPKK-----SLNG--QPGSG
424 DWRRCAENRAVGTPCTNGAVRQGDDEATL--EVIEVHRVGNSKEHLPLPSESGSNSYAPA
425 C------------------LERKNERNA-------------EAKRKMALARERKTVKTLG
426 IIMGTFILCWLPFFIVALVLPF-CESSCH-MPALLGAIINWLGYSNSLLNPVIYAYFNKD
427 FQNAFKKII-----KCKFCR--R-------------------------------------
428 ------------------------------------------------------------
429 ------------------------------
430 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
431 MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGS
432 HSSRSRDNASANDT------SATNM---TDDRYWSLTVYSHEHLVL-----TSVILGLFV
433 LCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--
434 LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIV
435 ALFI-SIPPLF-GWRDPNN--DPDKTGTCIISQDK----------GYTIFSTVGAFYLPM
436 LVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDST
437 TEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANG
438 CAEEASIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLA
439 IITGAFLICWLPFFIIALIGPF-VDPE-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPE
440 FRSAFQKIL-----FGKYRRGHR-------------------------------------
441 ------------------------------------------------------------
442 ------------------------------
443 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
444 MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGS
445 HSSRSRDNASANDT------SATNM---TDDRYWSLTVYSHEHLVL-----TSVILGLFV
446 LCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--
447 LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIV
448 ALFI-SIPPLF-GWRDPNN--DPDKTGTCIISQDK----------GYTIFSTVGAFYLPM
449 LVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDST
450 TEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANG
451 CAEEASIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLA
452 IITGAFLICWLPFFIIALIGPF-VDPE-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPE
453 FRSAFQKIL-----FGKYRRGHR-------------------------------------
454 ------------------------------------------------------------
455 ------------------------------
456 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
457 MEG-AEGQEELDWEAL--------------------------------------------
458 YLRLPLQNCSWNSTGWEPNWNVTVV---PNTTWWQASAPFDTPAALVRAAAKAVVLGLLI
459 LATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRWT--
460 LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTV
461 SFFV-CIAQLL-GWKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSFYVPV
462 LIILILYWRIYQTARKRIRR------RRGATARGGVGPPPVPAG----------------
463 -----------------GALVAGGGSGGIAAAVVAV-----IGRPLPTISETTTTGFTNV
464 SSNNTSPE--KQSCANGLEADPPTTGYGAVAAAYYPSLVRRKPKEAADSKRERKAAKTLA
465 IITGAFVACWLPFFVLAILVPT-CD--CE-VSPVLTSLSLWLGYFNSTLNPVIYTVFSPE
466 FRHAFQRLL-----CGRRVRRRRA----------------------------------PQ
467 ------------------------------------------------------------
468 ------------------------------
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