--- /dev/null
+************************************************************************
+ MSAPROBS is a open-source protein multiple sequence alignment algorithm
+ based on pair hidden markov model and partition function postirior
+ probabilities. If any comments or problems, please contact
+ Liu Yongchao(liuy0039@ntu.edu.sg or nkcslyc@hotmail.com)
+*************************************************************************
+Usage:
+ msaprobs [OPTION]... [infile]...
+
+Description:
+ Align sequences in multi-FASTA format
+
+ -o, --outfile <string>
+ specify the output file name (STDOUT by default)
+ -num_threads <integer>
+ specify the number of threads used, and otherwise detect automatically
+ -clustalw
+ use CLUSTALW output format instead of FASTA format
+
+ -c, --consistency REPS
+ use 0 <= REPS <= 5 (default: 2) passes of consistency transformation
+
+ -ir, --iterative-refinement REPS
+ use 0 <= REPS <= 1000 (default: 100) passes of iterative-refinement
+
+ -v, --verbose
+ report progress while aligning (default: off)
+
+ -annot FILENAME
+ write annotation for multiple alignment to FILENAME
+
+ -a, --alignment-order
+ print sequences in alignment order rather than input order (default: off)
+ -version
+ print out version of MSAPROBS
+