</head>
<body>
<p>
- <strong>What's new in Jalview 2.10.2 ?</strong>
- </p>
- <p>
- This August 2018 release of Jalview introduces new user interface
- features, improved and more extensible tree and PCA analysis, more
- robust 3D structure viewing with UCSF Chimera and an updated service
- client for JABAWS. The full list of bug fixes and new features can
- be found in the <a href="releases.html#Jalview.2.10.2"> 2.10.2
- Release Notes</a>, but the highlights are below.
+ <strong>What's new in Jalview 2.10.4b1 ?</strong>
</p>
+ <p>This is the first patch release for Jalview 2.10.4. It includes
+ the following new patches:</p>
<ul>
- <li><strong>New dialog and faster and more
- configurable Tree and PCA calculations</strong><br> Menu entries for
- calculating PCA and different types of tree have been replaced by
- a single <a href="calculations/calculations.html"><em>Calculations</em>
- dialog box</a>. The underlying implementation for the PCA and tree
- calculations have been made faster and more memory efficient.</li>
- <li><strong>Extensible score models</strong><br />A new
- framework has also been created for the score models used to
- calculate distances between sequences and shade alignments. This
- framework allows import of substitution matrices in NCBI and
- AAIndex format.<br /> <strong>PCA Bug Fixes</strong>. Jalview's
- implementation of PCA differed in its treatment of gaps and
- non-standard residues. The BLOSUM62 matrix also included a typo
- that affected results. See the <a
- href="releases.html#2102scoremodelbugs">2.10.2 release note
- about score model bugs</a> for details and how to reinstate legacy
- behaviour.</li>
- <li><strong>Update to JABAWS 2.2</strong><br />Jalview's
- alignment, protein conservation analysis, and protein disorder and
- RNA secondary structure prediction services are now provided by <a
- href="http://www.compbio.dundee.ac.uk/jabaws">JABAWS 2.2</a>.
- Several of the programs provided as JABAWS 2.2 services have been
- updated, so their options and parameters have changed.</li>
- <li><strong>URL linkouts to other bioinformatics
- databases</strong><br />New preferences for <a
- href="webServices/urllinks.html">opening web pages for
- database cross-references</a> via the UK Elixir's EMBL-EBI's MIRIAM
- database and identifiers.org services.</li>
- <li><strong>Showing and hiding regions</strong> <br /> <a
- href="menus/popupMenu.html#hideinserts">Hide insertions</a> in the
- PopUp menu has changed its behaviour. Prior to 2.10.2, columns
- were only shown or hidden according to gaps in the sequence under
- the popup menu. Now, only columns that are gapped in all selected
- sequences as well as the sequence under the popup menu are hidden,
- and column visibility outside the selected region is left as is.
- This makes it easy to filter insertions from the alignment view
- (just select the region containing insertions to remove) without
- affecting the rest of the hidden columns.</li>
- <li><strong>Gap count - a.k.a. the Occupancy
- Annotation Row</strong><br /> Another way to filter columns according to
- the presence of gaps is to enable the <strong>Occupancy
- Annotation</strong> row via Jalview's Preferences. This annotation row
- shows a histogram of the number of aligned residues at each
- column. The <a href="features/columnFilterByAnnotation.html">Select
- By Annotation</a> dialog now also includes a percentage threshold
- mode, to make it easy to filter alignments to show only those
- columns with a particular fraction of aligned sequences.</li>
- <li><strong>Recent search history for Find, PDBe and
- Uniprot</strong><br />Easily repeat a previous search for <a
- href="features/search.html#queryhistory">Find</a> and the free
- text search system (for querying Uniprot and the PDBe).</li>
- <li><strong>Improved Overview Window</strong><br />The <a
- href="features/overview.html">alignment overview</a> is now easier
- to use when working with alignments of more than 5000 rows and
- columns, and features a new pop-up menu that allows hidden regions
- to be excluded from the overview. It also works with CDS/Protein
- alignments and MSA views in wrapped mode.</li>
- <li><strong>3D Structure</strong><br />Jalview's communication
- with UCSF Chimera has been made more robust, particularly when
- working with many structures and long sequences. Regions in
- structures that correspond to hidden regions in an alignment view
- are now left un-coloured, making it easier to highlight specific
- features in 3D. See below for <a href="#experimental">experimental
- features for exchanging annotation between Chimera and Jalview.</a></li>
+ <li>HGVS nomenclature used for variant annotation retrieved
+ from Uniprot</li>
+ <li>Uniprot import fails for some sequences (Cannot import
+ features with multiple variant elements)</li>
+ <li>Clustal files with sequence positions in right-hand column
+ are now parsed correctly</li>
+ <li>Wrap view - export to SVG - IDs shown but not alignment
+ area in exported graphic</li>
+ <li>F2/Keyboard mode edits work when Overview window has input
+ focus</li>
+ <li>Windows specific fixes:
+ <ul>
+ <li>Annotation panel set too high when annotation added to
+ view</li>
+ <li>Updated search paths for Chimera default installation</li>
+ <li>Windows File Shortcuts can be dragged onto the Jalview
+ Desktop</li>
+ <li>Drag URL from Chrome, Firefox, IE to Jalview desktop on
+ Windows doesn't open file:<br /> Dragging the currently open
+ URL and links from a page viewed in Firefox or Chrome on
+ Windows is now fully supported.<br />
+ <strong>If you are using Edge</strong>, only links in the page
+ can be dragged.<br />
+ <strong>With Internet Explorer</strong>, only the currently open
+ URL in the browser can be dropped onto Jalview.
+ </li>
+ </ul>
+ </li>
</ul>
- <p>
- <strong>Scripting</strong><br />New <a
- href="http://www.jalview.org/examples/groovy">groovy examples</a>
- demonstrate Jalview 2.10.2 APIs for creation of data-driven
- colourschemes, and custom alignment file handlers. The <a
- href="groovy/featuresCounter.html">FeatureAnnotationWorker</a>
- introduced in Jalview 2.10 has also been refactored to allow
- efficient counting across multiple feature types. Please be aware
- that feature counter scripts created for earlier versions will not
- execute in Jalview 2.10.2.
- </p>
- <p>
- <strong><a name="experimental">Experimental Features</a></strong>
- </p>
- <p>
- This release of Jalview introduces an <em>Experimental Features</em>
- option in the Jalview Desktop's <em>Tools</em> menu that allows you
- to try out features that are still in development. To access the
- experimental features below - first enable the <strong>Tools→Enable
- Experimental Features</strong> option, and then restart Jalview.
- </p>
+ <p>Highlights in the 2.10.4 series include:</p>
<ul>
- <li><em>Annotation transfer between Chimera and Jalview</em><br />Two
- <a href="features/chimera.html#experimental">new entries in
- the Chimera viewer's Chimera menu</a> allow positional annotation to
- be exchanged between Chimera and Jalview.</li>
+ <li>Numerous efficiency improvements in the renderer and overview when working with large alignments with lots of hidden columns</li>
+ <li>Use of HTTPS when connecting to Uniprot, Ensembl and other EBI web services</li>
+ <li>Critical patches for running Jalview on OSX with Java 10</li>
+ <li>Easier adjustment of the Alignment ID panel and Annotation panel</li>
+ <li>Improved support for mapping between 3D Structures and Uniprot Protein Sequences</li>
+ <li>Improved support for discovering CDS and transcripts for Proteins and Ensembl gene IDs</li>
+ <li>New buttons on the Structure Chooser for adding structures
+ to an existing view, and disabling automatic superposition
+ according to linked alignments</li>
+ <li>Annotation transfer between Chimera and Jalview <em>(formerly only
+ available in 'Experimental' mode)</em></li>
</ul>
-
+ <p>
+ The full list of bugs fixed in this release can be found in the <a href="releases.html#Jalview.2.10.4">2.10.4
+ Release Notes</a>.
+ </p>
</body>
</html>