-<p><strong> Annotation Colouring </strong></p>
-<p>Jalview allows the columns of an alignment to be coloured using any
- numerical annotation rows added to that alignment. </p>
-Select "Colour" <strong>→</strong> "..
- by Annotation" to bring up the Colour by Annotation settings window. <br>
- <br><div align="center">
- <img src="annotationColourSetting.jpg" width="507" height="202"> </div>
-<ul>
- <li>Select which annotation to base the colouring scheme on using the top left
- selection box.</li>
- <li> If the "Use Original Colours" box is selected, the colouring
- scheme will use the colouring scheme present on the alignment before the Annotation
- Colour Settings window was displayed. </li>
+ <p>
+ <strong> Annotation Colouring </strong>
+ </p>
+ <p>Jalview allows the columns of an alignment to be coloured using
+ any numerical annotation rows added to that alignment.</p>
+ Select "Colour"
+ <strong>→</strong> ".. by Annotation" to bring up the
+ Colour by Annotation settings window.
+ <br>
+ <br>
+ <div align="center">
+ <img src="annotationColourSetting.gif" width="471" height="256">
+ </div>
+ <ul>
+ <li>Select which annotation to base the colouring scheme on using
+ the top left selection box.<br />If the <strong>Per-sequence
+ only</strong> tick box is not greyed out, then ticking it will limit the
+ available annotation rows to just those that are sequence associated
+ (e.g. T-COFFEE scores and <a
+ href="../webServices/proteinDisorder.html">protein disorder
+ predictions</a>), which will colour each sequence according to its own
+ per-residue scores.<br />
+ <em>Per-sequence associated annotation colouring was introduced
+ in Jalview 2.8</em>
+ </li>
+ <li>If the "Use Original Colours" box is selected, the
+ colouring scheme will use the colouring scheme present on the
+ alignment before the Annotation Colour Settings window was displayed.
+ <br /> <em><strong>Please Note:</strong> If no colour scheme was
+ applied previously, then the colours for lines and labels at each
+ position in the annotation row will be used, for secondary structure
+ symbols and graphs, this may be black by default, so your alignment
+ will be coloured black.</em>
+ </li>