help/html/calculations/scorematrices.html

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  22 <head>
  23 <title>Substitution matrices in Jalview</title>
  24 </head>
  25 <body>
  26 <strong>Substitution Matrices available in Jalview</strong>
  27 <p>Jalview includes a small number of built in substitution matrices, used for different types of analysis.</p>
  28 <ul>
  29 <li><a href="#blosum62">BLOSUM62</a> is the standard protein sequence alignment and analysis matrix.</li>
  30 <li><a href="#pam250">PAM250</a> is another standard protein matrix, and (since 2.8.1) is available for Tree and PCA calculations.</li>
  31 <li><a href="#simplenucleotide">Simple Nucleotide Substition</a> is a (fairly) arbitrary DNA/RNA substitution matrix.</li>
  32 <!--  <li><a href="#conservation">Conservation Matrices</a> A range of matrices for distinguishing amino-acids by physicochemical property conservation.
  33 </li> -->
  34 </ul>
  35
  36 <p><strong><a name="blosum62"></a>BLOSUM62</strong><br/>
  37 <table border="1">
  38 <tr><td></td><td>&nbsp;A&nbsp;</td><td>&nbsp;B&nbsp;</td><td>&nbsp;C&nbsp;</td><td>&nbsp;D&nbsp;</td><td>&nbsp;E&nbsp;</td><td>&nbsp;F&nbsp;</td><td>&nbsp;G&nbsp;</td><td>&nbsp;H&nbsp;</td><td>&nbsp;I&nbsp;</td><td>&nbsp;K&nbsp;</td><td>&nbsp;L&nbsp;</td><td>&nbsp;M&nbsp;</td><td>&nbsp;N&nbsp;</td><td>&nbsp;P&nbsp;</td><td>&nbsp;Q&nbsp;</td><td>&nbsp;R&nbsp;</td><td>&nbsp;S&nbsp;</td><td>&nbsp;T&nbsp;</td><td>&nbsp;U&nbsp;</td><td>&nbsp;V&nbsp;</td><td>&nbsp;W&nbsp;</td><td>&nbsp;X&nbsp;</td><td>&nbsp;Y&nbsp;</td><td>&nbsp;Z&nbsp;</td></tr>
  39 <tr><td>A</td><td>4</td><td>-2</td><td>0</td><td>-2</td><td>-1</td><td>-2</td><td>0</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td><td>1</td><td>0</td><td>0</td><td>0</td><td>-3</td><td>0</td><td>-2</td><td>-1</td></tr>
  40 <tr><td>B</td><td>-2</td><td>4</td><td>-3</td><td>4</td><td>1</td><td>-3</td><td>-1</td><td>0</td><td>-3</td><td>0</td><td>-4</td><td>-3</td><td>3</td><td>-2</td><td>0</td><td>-1</td><td>0</td><td>-1</td><td>-1</td><td>-3</td><td>-4</td><td>-1</td><td>-3</td><td>1</td></tr>
  41 <tr><td>C</td><td>0</td><td>-3</td><td>9</td><td>-3</td><td>-4</td><td>-2</td><td>-3</td><td>-3</td><td>-1</td><td>-3</td><td>-1</td><td>-1</td><td>-3</td><td>-3</td><td>-3</td><td>3</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>-2</td><td>-2</td><td>-2</td><td>-3</td></tr>
  42 <tr><td>D</td><td>-2</td><td>4</td><td>-3</td><td>6</td><td>2</td><td>-3</td><td>-1</td><td>-1</td><td>-3</td><td>-1</td><td>-4</td><td>-3</td><td>1</td><td>-1</td><td>0</td><td>-2</td><td>0</td><td>-1</td><td>-1</td><td>-3</td><td>-4</td><td>-1</td><td>-3</td><td>1</td></tr>
  43 <tr><td>E</td><td>-1</td><td>1</td><td>-4</td><td>2</td><td>5</td><td>-3</td><td>-2</td><td>0</td><td>-3</td><td>1</td><td>-3</td><td>-2</td><td>0</td><td>-1</td><td>2</td><td>0</td><td>0</td><td>-1</td><td>-1</td><td>-2</td><td>-3</td><td>-1</td><td>-2</td><td>4</td></tr>
  44 <tr><td>F</td><td>-2</td><td>-3</td><td>-2</td><td>-3</td><td>-3</td><td>6</td><td>-3</td><td>-1</td><td>0</td><td>-3</td><td>0</td><td>0</td><td>-3</td><td>-4</td><td>-3</td><td>-3</td><td>-2</td><td>-2</td><td>-1</td><td>-1</td><td>1</td><td>-1</td><td>3</td><td>-3</td></tr>
  45 <tr><td>G</td><td>0</td><td>-1</td><td>-3</td><td>-1</td><td>-2</td><td>-3</td><td>6</td><td>-2</td><td>-4</td><td>-2</td><td>-4</td><td>-3</td><td>0</td><td>-2</td><td>-2</td><td>-2</td><td>0</td><td>-2</td><td>-1</td><td>-3</td><td>-2</td><td>-1</td><td>-3</td><td>-2</td></tr>
  46 <tr><td>H</td><td>-2</td><td>0</td><td>-3</td><td>-1</td><td>0</td><td>-1</td><td>-2</td><td>8</td><td>-3</td><td>-1</td><td>-3</td><td>-2</td><td>1</td><td>-2</td><td>0</td><td>0</td><td>-1</td><td>-2</td><td>-1</td><td>-3</td><td>-2</td><td>-1</td><td>2</td><td>0</td></tr>
  47 <tr><td>I</td><td>-1</td><td>-3</td><td>-1</td><td>-3</td><td>-3</td><td>0</td><td>-4</td><td>-3</td><td>4</td><td>-3</td><td>2</td><td>1</td><td>-3</td><td>-3</td><td>-3</td><td>-3</td><td>-2</td><td>-1</td><td>-1</td><td>3</td><td>-3</td><td>-1</td><td>-1</td><td>-3</td></tr>
  48 <tr><td>K</td><td>-1</td><td>0</td><td>-3</td><td>-1</td><td>1</td><td>-3</td><td>-2</td><td>-1</td><td>-3</td><td>5</td><td>-2</td><td>-1</td><td>0</td><td>-1</td><td>1</td><td>2</td><td>0</td><td>-1</td><td>-1</td><td>-2</td><td>-3</td><td>-1</td><td>-2</td><td>1</td></tr>
  49 <tr><td>L</td><td>-1</td><td>-4</td><td>-1</td><td>-4</td><td>-3</td><td>0</td><td>-4</td><td>-3</td><td>2</td><td>-2</td><td>4</td><td>2</td><td>-3</td><td>-3</td><td>-2</td><td>-2</td><td>-2</td><td>-1</td><td>-1</td><td>1</td><td>-2</td><td>-1</td><td>-1</td><td>-3</td></tr>
  50 <tr><td>M</td><td>-1</td><td>-3</td><td>-1</td><td>-3</td><td>-2</td><td>0</td><td>-3</td><td>-2</td><td>1</td><td>-1</td><td>2</td><td>5</td><td>-2</td><td>-2</td><td>0</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td></tr>
  51 <tr><td>N</td><td>-2</td><td>3</td><td>-3</td><td>1</td><td>0</td><td>-3</td><td>0</td><td>1</td><td>-3</td><td>0</td><td>-3</td><td>-2</td><td>6</td><td>-2</td><td>0</td><td>0</td><td>1</td><td>0</td><td>-1</td><td>-3</td><td>-4</td><td>-1</td><td>-2</td><td>0</td></tr>
  52 <tr><td>P</td><td>-1</td><td>-2</td><td>-3</td><td>-1</td><td>-1</td><td>-4</td><td>-2</td><td>-2</td><td>-3</td><td>-1</td><td>-3</td><td>-2</td><td>-2</td><td>7</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-2</td><td>-2</td><td>-4</td><td>-2</td><td>-3</td><td>-1</td></tr>
  53 <tr><td>Q</td><td>-1</td><td>0</td><td>-3</td><td>0</td><td>2</td><td>-3</td><td>-2</td><td>0</td><td>-3</td><td>1</td><td>-2</td><td>0</td><td>0</td><td>-1</td><td>5</td><td>1</td><td>0</td><td>-1</td><td>-1</td><td>-2</td><td>-2</td><td>-1</td><td>-1</td><td>3</td></tr>
  54 <tr><td>R</td><td>-1</td><td>-1</td><td>-3</td><td>-2</td><td>0</td><td>-3</td><td>-2</td><td>0</td><td>-3</td><td>2</td><td>-2</td><td>-1</td><td>0</td><td>-2</td><td>1</td><td>5</td><td>-1</td><td>-1</td><td>-1</td><td>-3</td><td>-3</td><td>-1</td><td>-2</td><td>0</td></tr>
  55 <tr><td>S</td><td>1</td><td>0</td><td>-1</td><td>0</td><td>0</td><td>-2</td><td>0</td><td>-1</td><td>-2</td><td>0</td><td>-2</td><td>-1</td><td>1</td><td>-1</td><td>0</td><td>-1</td><td>4</td><td>1</td><td>0</td><td>-2</td><td>-3</td><td>0</td><td>-2</td><td>0</td></tr>
  56 <tr><td>T</td><td>0</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-2</td><td>-2</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>0</td><td>-1</td><td>-1</td><td>-1</td><td>1</td><td>5</td><td>0</td><td>0</td><td>-2</td><td>0</td><td>-2</td><td>-1</td></tr>
  57 <tr><td>U</td><td>0</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>0</td><td>0</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td></tr>
  58 <tr><td>V</td><td>0</td><td>-3</td><td>-1</td><td>-3</td><td>-2</td><td>-1</td><td>-3</td><td>-3</td><td>3</td><td>-2</td><td>1</td><td>1</td><td>-3</td><td>-2</td><td>-2</td><td>-3</td><td>-2</td><td>0</td><td>-1</td><td>4</td><td>-3</td><td>-1</td><td>-1</td><td>-2</td></tr>
  59 <tr><td>W</td><td>-3</td><td>-4</td><td>-2</td><td>-4</td><td>-3</td><td>1</td><td>-2</td><td>-2</td><td>-3</td><td>-3</td><td>-2</td><td>-1</td><td>-4</td><td>-4</td><td>-2</td><td>-3</td><td>-3</td><td>-2</td><td>-2</td><td>-3</td><td>11</td><td>-2</td><td>2</td><td>-3</td></tr>
  60 <tr><td>X</td><td>0</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>0</td><td>0</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td></tr>
  61 <tr><td>Y</td><td>-2</td><td>-3</td><td>-2</td><td>-3</td><td>-2</td><td>3</td><td>-3</td><td>2</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-2</td><td>-3</td><td>-1</td><td>-2</td><td>-2</td><td>-2</td><td>-1</td><td>-1</td><td>2</td><td>-1</td><td>7</td><td>-2</td></tr>
  62 <tr><td>Z</td><td>-1</td><td>1</td><td>-3</td><td>1</td><td>4</td><td>-3</td><td>-2</td><td>0</td><td>-3</td><td>1</td><td>-3</td><td>-1</td><td>0</td><td>-1</td><td>3</td><td>0</td><td>0</td><td>-1</td><td>-1</td><td>-2</td><td>-3</td><td>-1</td><td>-2</td><td>4</td></tr>
  63 </table>
  64 <p><strong><a name="pam250">PAM250</a></strong><br/>
  65 <em><strong>P</strong>ercentage <strong>A</strong>ccepted <strong>M</strong>utation matrix. PAM250 estimates substitutions after 250% of sites have changed (each site can be mutated multple times).<br/>
  66 Jalview 2.8.1 introduced support for PAM250 based <a href="../calculations/pca.html">PCA</a> and <a href="../calculations/trees.html">tree</a> calculations.</em>
  67 <table border="1">
  68 <tr><td></td><td>&nbsp;A&nbsp;</td><td>&nbsp;B&nbsp;</td><td>&nbsp;C&nbsp;</td><td>&nbsp;D&nbsp;</td><td>&nbsp;E&nbsp;</td><td>&nbsp;F&nbsp;</td><td>&nbsp;G&nbsp;</td><td>&nbsp;H&nbsp;</td><td>&nbsp;I&nbsp;</td><td>&nbsp;K&nbsp;</td><td>&nbsp;L&nbsp;</td><td>&nbsp;M&nbsp;</td><td>&nbsp;N&nbsp;</td><td>&nbsp;P&nbsp;</td><td>&nbsp;Q&nbsp;</td><td>&nbsp;R&nbsp;</td><td>&nbsp;S&nbsp;</td><td>&nbsp;T&nbsp;</td><td>&nbsp;U&nbsp;</td><td>&nbsp;V&nbsp;</td><td>&nbsp;W&nbsp;</td><td>&nbsp;X&nbsp;</td><td>&nbsp;Y&nbsp;</td><td>&nbsp;Z&nbsp;</td></tr>
  69 <tr><td>A</td><td>2</td><td>0</td><td>-2</td><td>0</td><td>0</td><td>-3</td><td>1</td><td>-1</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>0</td><td>1</td><td>0</td><td>-2</td><td>1</td><td>1</td><td>0</td><td>0</td><td>-6</td><td>0</td><td>-3</td><td>0</td></tr>
  70 <tr><td>B</td><td>0</td><td>3</td><td>-4</td><td>3</td><td>3</td><td>-4</td><td>0</td><td>1</td><td>-2</td><td>1</td><td>-3</td><td>-2</td><td>2</td><td>-1</td><td>1</td><td>-1</td><td>0</td><td>0</td><td>-1</td><td>-2</td><td>-5</td><td>-1</td><td>-3</td><td>2</td></tr>
  71 <tr><td>C</td><td>-2</td><td>-4</td><td>12</td><td>-5</td><td>-5</td><td>-4</td><td>-3</td><td>-3</td><td>-2</td><td>-5</td><td>-6</td><td>-5</td><td>-4</td><td>-3</td><td>-5</td><td>-4</td><td>0</td><td>-2</td><td>-3</td><td>-2</td><td>-8</td><td>-3</td><td>0</td><td>-5</td></tr>
  72 <tr><td>D</td><td>0</td><td>3</td><td>-5</td><td>4</td><td>3</td><td>-6</td><td>1</td><td>1</td><td>-2</td><td>0</td><td>-4</td><td>-3</td><td>2</td><td>-1</td><td>2</td><td>-1</td><td>0</td><td>0</td><td>-1</td><td>-2</td><td>-7</td><td>-1</td><td>-4</td><td>3</td></tr>
  73 <tr><td>E</td><td>0</td><td>3</td><td>-5</td><td>3</td><td>4</td><td>-5</td><td>0</td><td>1</td><td>-2</td><td>0</td><td>-3</td><td>-2</td><td>1</td><td>-1</td><td>2</td><td>-1</td><td>0</td><td>0</td><td>-1</td><td>-2</td><td>-7</td><td>-1</td><td>-4</td><td>3</td></tr>
  74 <tr><td>F</td><td>-3</td><td>-4</td><td>-4</td><td>-6</td><td>-5</td><td>9</td><td>-5</td><td>-2</td><td>1</td><td>-5</td><td>2</td><td>0</td><td>-3</td><td>-5</td><td>-5</td><td>-4</td><td>-3</td><td>-3</td><td>-2</td><td>-1</td><td>0</td><td>-2</td><td>7</td><td>-5</td></tr>
  75 <tr><td>G</td><td>1</td><td>0</td><td>-3</td><td>1</td><td>0</td><td>-5</td><td>5</td><td>-2</td><td>-3</td><td>-2</td><td>-4</td><td>-3</td><td>0</td><td>0</td><td>-1</td><td>-3</td><td>1</td><td>0</td><td>-1</td><td>-1</td><td>-7</td><td>-1</td><td>-5</td><td>0</td></tr>
  76 <tr><td>H</td><td>-1</td><td>1</td><td>-3</td><td>1</td><td>1</td><td>-2</td><td>-2</td><td>6</td><td>-2</td><td>0</td><td>-2</td><td>-2</td><td>2</td><td>0</td><td>3</td><td>2</td><td>-1</td><td>-1</td><td>-1</td><td>-2</td><td>-3</td><td>-1</td><td>0</td><td>2</td></tr>
  77 <tr><td>I</td><td>-1</td><td>-2</td><td>-2</td><td>-2</td><td>-2</td><td>1</td><td>-3</td><td>-2</td><td>5</td><td>-2</td><td>2</td><td>2</td><td>-2</td><td>-2</td><td>-2</td><td>-2</td><td>-1</td><td>0</td><td>-1</td><td>4</td><td>-5</td><td>-1</td><td>-1</td><td>-2</td></tr>
  78 <tr><td>K</td><td>-1</td><td>1</td><td>-5</td><td>0</td><td>0</td><td>-5</td><td>-2</td><td>0</td><td>-2</td><td>5</td><td>-3</td><td>0</td><td>1</td><td>-1</td><td>1</td><td>3</td><td>0</td><td>0</td><td>-1</td><td>-2</td><td>-3</td><td>-1</td><td>-4</td><td>0</td></tr>
  79 <tr><td>L</td><td>-2</td><td>-3</td><td>-6</td><td>-4</td><td>-3</td><td>2</td><td>-4</td><td>-2</td><td>2</td><td>-3</td><td>6</td><td>4</td><td>-3</td><td>-3</td><td>-2</td><td>-3</td><td>-3</td><td>-2</td><td>-1</td><td>2</td><td>-2</td><td>-1</td><td>-1</td><td>-3</td></tr>
  80 <tr><td>M</td><td>-1</td><td>-2</td><td>-5</td><td>-3</td><td>-2</td><td>0</td><td>-3</td><td>-2</td><td>2</td><td>0</td><td>4</td><td>6</td><td>-2</td><td>-2</td><td>-1</td><td>0</td><td>-2</td><td>-1</td><td>-1</td><td>2</td><td>-4</td><td>-1</td><td>-2</td><td>-2</td></tr>
  81 <tr><td>N</td><td>0</td><td>2</td><td>-4</td><td>2</td><td>1</td><td>-3</td><td>0</td><td>2</td><td>-2</td><td>1</td><td>-3</td><td>-2</td><td>2</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>-2</td><td>-4</td><td>0</td><td>-2</td><td>1</td></tr>
  82 <tr><td>P</td><td>1</td><td>-1</td><td>-3</td><td>-1</td><td>-1</td><td>-5</td><td>0</td><td>0</td><td>-2</td><td>-1</td><td>-3</td><td>-2</td><td>0</td><td>6</td><td>0</td><td>0</td><td>1</td><td>0</td><td>-1</td><td>-1</td><td>-6</td><td>-1</td><td>-5</td><td>0</td></tr>
  83 <tr><td>Q</td><td>0</td><td>1</td><td>-5</td><td>2</td><td>2</td><td>-5</td><td>-1</td><td>3</td><td>-2</td><td>1</td><td>-2</td><td>-1</td><td>1</td><td>0</td><td>4</td><td>1</td><td>-1</td><td>-1</td><td>-1</td><td>-2</td><td>-5</td><td>-1</td><td>-4</td><td>3</td></tr>
  84 <tr><td>R</td><td>-2</td><td>-1</td><td>-4</td><td>-1</td><td>-1</td><td>-4</td><td>-3</td><td>2</td><td>-2</td><td>3</td><td>-3</td><td>0</td><td>0</td><td>0</td><td>1</td><td>6</td><td>0</td><td>-1</td><td>-1</td><td>-2</td><td>2</td><td>-1</td><td>-4</td><td>0</td></tr>
  85 <tr><td>S</td><td>1</td><td>0</td><td>0</td><td>0</td><td>0</td><td>-3</td><td>1</td><td>-1</td><td>-1</td><td>0</td><td>-3</td><td>-2</td><td>1</td><td>1</td><td>-1</td><td>0</td><td>2</td><td>1</td><td>0</td><td>-1</td><td>-2</td><td>0</td><td>-3</td><td>0</td></tr>
  86 <tr><td>T</td><td>1</td><td>0</td><td>-2</td><td>0</td><td>0</td><td>-3</td><td>0</td><td>-1</td><td>0</td><td>0</td><td>-2</td><td>-1</td><td>0</td><td>0</td><td>-1</td><td>-1</td><td>1</td><td>3</td><td>0</td><td>0</td><td>-5</td><td>0</td><td>-3</td><td>-1</td></tr>
  87 <tr><td>U</td><td>0</td><td>-1</td><td>-3</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>0</td><td>-1</td><td>-1</td><td>-1</td><td>0</td><td>0</td><td>-1</td><td>-1</td><td>-4</td><td>-1</td><td>-2</td><td>-1</td></tr>
  88 <tr><td>V</td><td>0</td><td>-2</td><td>-2</td><td>-2</td><td>-2</td><td>-1</td><td>-1</td><td>-2</td><td>4</td><td>-2</td><td>2</td><td>2</td><td>-2</td><td>-1</td><td>-2</td><td>-2</td><td>-1</td><td>0</td><td>-1</td><td>4</td><td>-6</td><td>-1</td><td>-2</td><td>-2</td></tr>
  89 <tr><td>W</td><td>-6</td><td>-5</td><td>-8</td><td>-7</td><td>-7</td><td>0</td><td>-7</td><td>-3</td><td>-5</td><td>-3</td><td>-2</td><td>-4</td><td>-4</td><td>-6</td><td>-5</td><td>2</td><td>-2</td><td>-5</td><td>-4</td><td>-6</td><td>17</td><td>-4</td><td>0</td><td>-6</td></tr>
  90 <tr><td>X</td><td>0</td><td>-1</td><td>-3</td><td>-1</td><td>-1</td><td>-2</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>-1</td><td>0</td><td>-1</td><td>-1</td><td>-1</td><td>0</td><td>0</td><td>-1</td><td>-1</td><td>-4</td><td>-1</td><td>-2</td><td>-1</td></tr>
  91 <tr><td>Y</td><td>-3</td><td>-3</td><td>0</td><td>-4</td><td>-4</td><td>7</td><td>-5</td><td>0</td><td>-1</td><td>-4</td><td>-1</td><td>-2</td><td>-2</td><td>-5</td><td>-4</td><td>-4</td><td>-3</td><td>-3</td><td>-2</td><td>-2</td><td>0</td><td>-2</td><td>10</td><td>-4</td></tr>
  92 <tr><td>Z</td><td>0</td><td>2</td><td>-5</td><td>3</td><td>3</td><td>-5</td><td>0</td><td>2</td><td>-2</td><td>0</td><td>-3</td><td>-2</td><td>1</td><td>0</td><td>3</td><td>0</td><td>0</td><td>-1</td><td>-1</td><td>-2</td><td>-6</td><td>-1</td><td>-4</td><td>3</td></tr>
  93 </table>
  94
  95 <p><strong><a name="simplenucleotide">Simple Nucleotide Substitution</a></strong><br>
  96 This is an ad-hoc matrix which, in addition to penalising mutations between the common nucleotides (ACGT), includes T/U equivalence in order to allow both DNA and/or RNA.
  97 In addition, it encodes weak equivalence between R and Y with AG and CTU, respectively, and N is allowed to match any other base weakly. This matrix also includes I (Inosine) and X (Xanthine), but encodes them to weakly match any of (ACGTU), and unfavourably match each other.
  98 <table border="1">
  99 <tr><td></td><td>&nbsp;A&nbsp;</td><td>&nbsp;C&nbsp;</td><td>&nbsp;G&nbsp;</td><td>&nbsp;I&nbsp;</td><td>&nbsp;N&nbsp;</td><td>&nbsp;R&nbsp;</td><td>&nbsp;T&nbsp;</td><td>&nbsp;U&nbsp;</td><td>&nbsp;X&nbsp;</td><td>&nbsp;Y&nbsp;</td></tr>
 100 <tr><td>A</td><td>10</td><td>-8</td><td>-8</td><td>1</td><td>1</td><td>1</td><td>-8</td><td>-8</td><td>1</td><td>-8</td></tr>
 101 <tr><td>C</td><td>-8</td><td>10</td><td>-8</td><td>1</td><td>1</td><td>-8</td><td>-8</td><td>-8</td><td>1</td><td>1</td></tr>
 102 <tr><td>G</td><td>-8</td><td>-8</td><td>10</td><td>1</td><td>1</td><td>1</td><td>-8</td><td>-8</td><td>1</td><td>-8</td></tr>
 103 <tr><td>I</td><td>1</td><td>1</td><td>1</td><td>10</td><td>1</td><td>0</td><td>1</td><td>1</td><td>0</td><td>0</td></tr>
 104 <tr><td>N</td><td>1</td><td>1</td><td>1</td><td>1</td><td>10</td><td>1</td><td>1</td><td>1</td><td>1</td><td>1</td></tr>
 105 <tr><td>R</td><td>1</td><td>-8</td><td>1</td><td>0</td><td>1</td><td>10</td><td>-8</td><td>-8</td><td>0</td><td>-8</td></tr>
 106 <tr><td>T</td><td>-8</td><td>-8</td><td>-8</td><td>1</td><td>1</td><td>-8</td><td>10</td><td>10</td><td>1</td><td>1</td></tr>
 107 <tr><td>U</td><td>-8</td><td>-8</td><td>-8</td><td>1</td><td>1</td><td>-8</td><td>10</td><td>10</td><td>1</td><td>1</td></tr>
 108 <tr><td>X</td><td>1</td><td>1</td><td>1</td><td>0</td><td>1</td><td>0</td><td>1</td><td>1</td><td>10</td><td>0</td></tr>
 109 <tr><td>Y</td><td>-8</td><td>1</td><td>-8</td><td>0</td><td>1</td><td>-8</td><td>1</td><td>1</td><td>0</td><td>10</td></tr>
 110 </table>
 111 <strong><em>This nucleotide matrix was introduced in
 112                                 Jalview 2.8. If you'd like to improve it - please take a look at <a
 113                                 href="http://issues.jalview.org/browse/JAL-1027">Issue JAL-1027
 114                                         - introduce a nucleotide substitution matrix that supports RNA/DNA
 115                                         and ambiguity codes</a>
 116                 </em></strong>
 117                 </p>
 118 <!--  <p><strong><a name="conservation">Physicochemical property conservation</a></strong><br>
 119 Three different matrices are provided which reflect differences in physicochemical properties for different amino-acids.
 120 <ul><li><em>Conservation Both</em><br>Matrix elements count number of properties shared, and number of properties that both amino-acids *do not* have (e.g. hydrophobic and not polar).
 121
 122 <table border="1"><tr><td></td><td>&nbsp;A&nbsp;</td><td>&nbsp;B&nbsp;</td><td>&nbsp;C&nbsp;</td><td>&nbsp;D&nbsp;</td><td>&nbsp;E&nbsp;</td><td>&nbsp;F&nbsp;</td><td>&nbsp;G&nbsp;</td><td>&nbsp;H&nbsp;</td><td>&nbsp;I&nbsp;</td><td>&nbsp;K&nbsp;</td><td>&nbsp;L&nbsp;</td><td>&nbsp;M&nbsp;</td><td>&nbsp;N&nbsp;</td><td>&nbsp;P&nbsp;</td><td>&nbsp;Q&nbsp;</td><td>&nbsp;R&nbsp;</td><td>&nbsp;S&nbsp;</td><td>&nbsp;T&nbsp;</td><td>&nbsp;U&nbsp;</td><td>&nbsp;V&nbsp;</td><td>&nbsp;W&nbsp;</td><td>&nbsp;X&nbsp;</td><td>&nbsp;Y&nbsp;</td><td>&nbsp;Z&nbsp;</td></tr>
 123 <tr><td>A</td><td>20</td><td>0</td><td>18</td><td>10</td><td>8</td><td>14</td><td>20</td><td>8</td><td>14</td><td>10</td><td>14</td><td>16</td><td>14</td><td>14</td><td>12</td><td>8</td><td>16</td><td>14</td><td>2</td><td>16</td><td>12</td><td>2</td><td>12</td><td>0</td></tr>
 124 <tr><td>B</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>
 125 <tr><td>C</td><td>18</td><td>0</td><td>18</td><td>12</td><td>10</td><td>16</td><td>18</td><td>10</td><td>16</td><td>12</td><td>16</td><td>18</td><td>16</td><td>16</td><td>14</td><td>10</td><td>14</td><td>16</td><td>2</td><td>18</td><td>14</td><td>2</td><td>14</td><td>0</td></tr>
 126 <tr><td>D</td><td>10</td><td>0</td><td>12</td><td>18</td><td>18</td><td>8</td><td>10</td><td>10</td><td>8</td><td>12</td><td>8</td><td>10</td><td>16</td><td>12</td><td>14</td><td>14</td><td>14</td><td>16</td><td>2</td><td>10</td><td>10</td><td>2</td><td>10</td><td>0</td></tr>
 127 <tr><td>E</td><td>8</td><td>0</td><td>10</td><td>18</td><td>14</td><td>10</td><td>8</td><td>12</td><td>10</td><td>14</td><td>10</td><td>12</td><td>14</td><td>10</td><td>16</td><td>16</td><td>12</td><td>14</td><td>2</td><td>8</td><td>12</td><td>2</td><td>12</td><td>0</td></tr>
 128 <tr><td>F</td><td>14</td><td>0</td><td>16</td><td>8</td><td>10</td><td>18</td><td>14</td><td>14</td><td>16</td><td>12</td><td>16</td><td>18</td><td>12</td><td>12</td><td>14</td><td>10</td><td>10</td><td>12</td><td>2</td><td>14</td><td>18</td><td>2</td><td>18</td><td>0</td></tr>
 129 <tr><td>G</td><td>20</td><td>0</td><td>18</td><td>10</td><td>8</td><td>14</td><td>16</td><td>8</td><td>14</td><td>10</td><td>14</td><td>16</td><td>14</td><td>14</td><td>12</td><td>8</td><td>16</td><td>14</td><td>2</td><td>16</td><td>12</td><td>2</td><td>12</td><td>0</td></tr>
 130 <tr><td>H</td><td>8</td><td>0</td><td>10</td><td>10</td><td>12</td><td>14</td><td>8</td><td>18</td><td>10</td><td>18</td><td>10</td><td>12</td><td>10</td><td>6</td><td>12</td><td>16</td><td>8</td><td>10</td><td>4</td><td>8</td><td>16</td><td>4</td><td>16</td><td>0</td></tr>
 131 <tr><td>I</td><td>14</td><td>0</td><td>16</td><td>8</td><td>10</td><td>16</td><td>14</td><td>10</td><td>20</td><td>12</td><td>20</td><td>18</td><td>12</td><td>12</td><td>14</td><td>10</td><td>10</td><td>12</td><td>2</td><td>18</td><td>14</td><td>2</td><td>14</td><td>0</td></tr>
 132 <tr><td>K</td><td>10</td><td>0</td><td>12</td><td>12</td><td>14</td><td>12</td><td>10</td><td>18</td><td>12</td><td>14</td><td>12</td><td>14</td><td>12</td><td>8</td><td>14</td><td>18</td><td>10</td><td>12</td><td>4</td><td>10</td><td>14</td><td>4</td><td>14</td><td>0</td></tr>
 133 <tr><td>L</td><td>14</td><td>0</td><td>16</td><td>8</td><td>10</td><td>16</td><td>14</td><td>10</td><td>20</td><td>12</td><td>18</td><td>18</td><td>12</td><td>12</td><td>14</td><td>10</td><td>10</td><td>12</td><td>2</td><td>18</td><td>14</td><td>2</td><td>14</td><td>0</td></tr>
 134 <tr><td>M</td><td>16</td><td>0</td><td>18</td><td>10</td><td>12</td><td>18</td><td>16</td><td>12</td><td>18</td><td>14</td><td>18</td><td>18</td><td>14</td><td>14</td><td>16</td><td>12</td><td>12</td><td>14</td><td>2</td><td>16</td><td>16</td><td>2</td><td>16</td><td>0</td></tr>
 135 <tr><td>N</td><td>14</td><td>0</td><td>16</td><td>16</td><td>14</td><td>12</td><td>14</td><td>10</td><td>12</td><td>12</td><td>12</td><td>14</td><td>20</td><td>16</td><td>18</td><td>14</td><td>18</td><td>20</td><td>2</td><td>14</td><td>14</td><td>2</td><td>14</td><td>0</td></tr>
 136 <tr><td>P</td><td>14</td><td>0</td><td>16</td><td>12</td><td>10</td><td>12</td><td>14</td><td>6</td><td>12</td><td>8</td><td>12</td><td>14</td><td>16</td><td>16</td><td>14</td><td>10</td><td>14</td><td>16</td><td>0</td><td>14</td><td>10</td><td>0</td><td>10</td><td>0</td></tr>
 137 <tr><td>Q</td><td>12</td><td>0</td><td>14</td><td>14</td><td>16</td><td>14</td><td>12</td><td>12</td><td>14</td><td>14</td><td>14</td><td>16</td><td>18</td><td>14</td><td>18</td><td>16</td><td>16</td><td>18</td><td>2</td><td>12</td><td>16</td><td>2</td><td>16</td><td>0</td></tr>
 138 <tr><td>R</td><td>8</td><td>0</td><td>10</td><td>14</td><td>16</td><td>10</td><td>8</td><td>16</td><td>10</td><td>18</td><td>10</td><td>12</td><td>14</td><td>10</td><td>16</td><td>18</td><td>12</td><td>14</td><td>2</td><td>8</td><td>12</td><td>2</td><td>12</td><td>0</td></tr>
 139 <tr><td>S</td><td>16</td><td>0</td><td>14</td><td>14</td><td>12</td><td>10</td><td>16</td><td>8</td><td>10</td><td>10</td><td>10</td><td>12</td><td>18</td><td>14</td><td>16</td><td>12</td><td>18</td><td>18</td><td>2</td><td>12</td><td>12</td><td>2</td><td>12</td><td>0</td></tr>
 140 <tr><td>T</td><td>14</td><td>0</td><td>16</td><td>16</td><td>14</td><td>12</td><td>14</td><td>10</td><td>12</td><td>12</td><td>12</td><td>14</td><td>20</td><td>16</td><td>18</td><td>14</td><td>18</td><td>14</td><td>2</td><td>14</td><td>14</td><td>2</td><td>14</td><td>0</td></tr>
 141 <tr><td>U</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>4</td><td>0</td><td>4</td><td>0</td></tr>
 142 <tr><td>V</td><td>16</td><td>0</td><td>18</td><td>10</td><td>8</td><td>14</td><td>16</td><td>8</td><td>18</td><td>10</td><td>18</td><td>16</td><td>14</td><td>14</td><td>12</td><td>8</td><td>12</td><td>14</td><td>2</td><td>2</td><td>12</td><td>2</td><td>12</td><td>0</td></tr>
 143 <tr><td>W</td><td>12</td><td>0</td><td>14</td><td>10</td><td>12</td><td>18</td><td>12</td><td>16</td><td>14</td><td>14</td><td>14</td><td>16</td><td>14</td><td>10</td><td>16</td><td>12</td><td>12</td><td>14</td><td>4</td><td>12</td><td>20</td><td>4</td><td>20</td><td>0</td></tr>
 144 <tr><td>X</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>4</td><td>0</td><td>4</td><td>0</td></tr>
 145 <tr><td>Y</td><td>12</td><td>0</td><td>14</td><td>10</td><td>12</td><td>18</td><td>12</td><td>16</td><td>14</td><td>14</td><td>14</td><td>16</td><td>14</td><td>10</td><td>16</td><td>12</td><td>12</td><td>14</td><td>4</td><td>12</td><td>20</td><td>4</td><td>12</td><td>0</td></tr>
 146 <tr><td>Z</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>
 147 </table>
 148
 149 <li><em>Conservation Pos</em><br>Count number of properties that amino acids both have in common.
 150
 151 <table border="1"><tr><td></td><td>&nbsp;A&nbsp;</td><td>&nbsp;B&nbsp;</td><td>&nbsp;C&nbsp;</td><td>&nbsp;D&nbsp;</td><td>&nbsp;E&nbsp;</td><td>&nbsp;F&nbsp;</td><td>&nbsp;G&nbsp;</td><td>&nbsp;H&nbsp;</td><td>&nbsp;I&nbsp;</td><td>&nbsp;K&nbsp;</td><td>&nbsp;L&nbsp;</td><td>&nbsp;M&nbsp;</td><td>&nbsp;N&nbsp;</td><td>&nbsp;P&nbsp;</td><td>&nbsp;Q&nbsp;</td><td>&nbsp;R&nbsp;</td><td>&nbsp;S&nbsp;</td><td>&nbsp;T&nbsp;</td><td>&nbsp;U&nbsp;</td><td>&nbsp;V&nbsp;</td><td>&nbsp;W&nbsp;</td><td>&nbsp;X&nbsp;</td><td>&nbsp;Y&nbsp;</td><td>&nbsp;Z&nbsp;</td></tr>
 152 <tr><td>A</td><td>6</td><td>0</td><td>4</td><td>2</td><td>0</td><td>2</td><td>6</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>0</td><td>4</td><td>2</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 153 <tr><td>B</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>
 154 <tr><td>C</td><td>4</td><td>0</td><td>4</td><td>2</td><td>0</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>0</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 155 <tr><td>D</td><td>2</td><td>0</td><td>2</td><td>6</td><td>6</td><td>0</td><td>2</td><td>4</td><td>0</td><td>4</td><td>0</td><td>0</td><td>4</td><td>2</td><td>2</td><td>4</td><td>4</td><td>4</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 156 <tr><td>E</td><td>0</td><td>0</td><td>0</td><td>6</td><td>4</td><td>0</td><td>0</td><td>4</td><td>0</td><td>4</td><td>0</td><td>0</td><td>2</td><td>0</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 157 <tr><td>F</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>4</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>2</td><td>2</td><td>4</td><td>2</td><td>4</td><td>0</td></tr>
 158 <tr><td>G</td><td>6</td><td>0</td><td>4</td><td>2</td><td>0</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>0</td><td>4</td><td>2</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 159 <tr><td>H</td><td>2</td><td>0</td><td>2</td><td>4</td><td>4</td><td>4</td><td>2</td><td>8</td><td>2</td><td>8</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>6</td><td>2</td><td>2</td><td>4</td><td>2</td><td>6</td><td>4</td><td>6</td><td>0</td></tr>
 160 <tr><td>I</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>4</td><td>2</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 161 <tr><td>K</td><td>2</td><td>0</td><td>2</td><td>4</td><td>4</td><td>2</td><td>2</td><td>8</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>6</td><td>2</td><td>2</td><td>4</td><td>2</td><td>4</td><td>4</td><td>4</td><td>0</td></tr>
 162 <tr><td>L</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>4</td><td>2</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 163 <tr><td>M</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 164 <tr><td>N</td><td>2</td><td>0</td><td>2</td><td>4</td><td>2</td><td>0</td><td>2</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>4</td><td>2</td><td>2</td><td>2</td><td>4</td><td>4</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 165 <tr><td>P</td><td>2</td><td>0</td><td>2</td><td>2</td><td>0</td><td>0</td><td>2</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>2</td><td>2</td><td>0</td><td>0</td><td>2</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>
 166 <tr><td>Q</td><td>0</td><td>0</td><td>0</td><td>2</td><td>2</td><td>0</td><td>0</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 167 <tr><td>R</td><td>0</td><td>0</td><td>0</td><td>4</td><td>4</td><td>0</td><td>0</td><td>6</td><td>0</td><td>6</td><td>0</td><td>0</td><td>2</td><td>0</td><td>2</td><td>6</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 168 <tr><td>S</td><td>4</td><td>0</td><td>2</td><td>4</td><td>2</td><td>0</td><td>4</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>4</td><td>2</td><td>2</td><td>2</td><td>4</td><td>4</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 169 <tr><td>T</td><td>2</td><td>0</td><td>2</td><td>4</td><td>2</td><td>0</td><td>2</td><td>2</td><td>0</td><td>2</td><td>0</td><td>0</td><td>4</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 170 <tr><td>U</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>4</td><td>0</td><td>4</td><td>0</td></tr>
 171 <tr><td>V</td><td>4</td><td>0</td><td>4</td><td>2</td><td>0</td><td>2</td><td>4</td><td>2</td><td>4</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td></tr>
 172 <tr><td>W</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>6</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>6</td><td>4</td><td>6</td><td>0</td></tr>
 173 <tr><td>X</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>4</td><td>0</td><td>4</td><td>0</td></tr>
 174 <tr><td>Y</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>6</td><td>2</td><td>4</td><td>2</td><td>2</td><td>2</td><td>0</td><td>2</td><td>2</td><td>2</td><td>2</td><td>4</td><td>2</td><td>6</td><td>4</td><td>4</td><td>0</td></tr>
 175 <tr><td>Z</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>
 176 </table>
 177
 178 </li>
 179 <li>
 180 <em>Conservation EnhPos</em><br>Distinguish amino acids based on properties they have in common or lack, emphasising those they have in common.
 181
 182 <table border="1"><tr><td></td><td>&nbsp;A&nbsp;</td><td>&nbsp;B&nbsp;</td><td>&nbsp;C&nbsp;</td><td>&nbsp;D&nbsp;</td><td>&nbsp;E&nbsp;</td><td>&nbsp;F&nbsp;</td><td>&nbsp;G&nbsp;</td><td>&nbsp;H&nbsp;</td><td>&nbsp;I&nbsp;</td><td>&nbsp;K&nbsp;</td><td>&nbsp;L&nbsp;</td><td>&nbsp;M&nbsp;</td><td>&nbsp;N&nbsp;</td><td>&nbsp;P&nbsp;</td><td>&nbsp;Q&nbsp;</td><td>&nbsp;R&nbsp;</td><td>&nbsp;S&nbsp;</td><td>&nbsp;T&nbsp;</td><td>&nbsp;U&nbsp;</td><td>&nbsp;V&nbsp;</td><td>&nbsp;W&nbsp;</td><td>&nbsp;X&nbsp;</td><td>&nbsp;Y&nbsp;</td><td>&nbsp;Z&nbsp;</td></tr>
 183 <tr><td>A</td><td>16</td><td>0</td><td>13</td><td>7</td><td>4</td><td>9</td><td>16</td><td>6</td><td>9</td><td>7</td><td>9</td><td>10</td><td>9</td><td>9</td><td>6</td><td>4</td><td>12</td><td>9</td><td>3</td><td>12</td><td>8</td><td>3</td><td>8</td><td>0</td></tr>
 184 <tr><td>B</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>
 185 <tr><td>C</td><td>13</td><td>0</td><td>13</td><td>8</td><td>5</td><td>10</td><td>13</td><td>7</td><td>10</td><td>8</td><td>10</td><td>11</td><td>10</td><td>10</td><td>7</td><td>5</td><td>9</td><td>10</td><td>3</td><td>13</td><td>9</td><td>3</td><td>9</td><td>0</td></tr>
 186 <tr><td>D</td><td>7</td><td>0</td><td>8</td><td>15</td><td>15</td><td>4</td><td>7</td><td>9</td><td>4</td><td>10</td><td>4</td><td>5</td><td>12</td><td>8</td><td>9</td><td>11</td><td>11</td><td>12</td><td>3</td><td>7</td><td>7</td><td>3</td><td>7</td><td>0</td></tr>
 187 <tr><td>E</td><td>4</td><td>0</td><td>5</td><td>15</td><td>11</td><td>5</td><td>4</td><td>10</td><td>5</td><td>11</td><td>5</td><td>6</td><td>9</td><td>5</td><td>10</td><td>12</td><td>8</td><td>9</td><td>3</td><td>4</td><td>8</td><td>3</td><td>8</td><td>0</td></tr>
 188 <tr><td>F</td><td>9</td><td>0</td><td>10</td><td>4</td><td>5</td><td>13</td><td>9</td><td>11</td><td>10</td><td>8</td><td>10</td><td>11</td><td>6</td><td>6</td><td>7</td><td>5</td><td>5</td><td>6</td><td>3</td><td>9</td><td>13</td><td>3</td><td>13</td><td>0</td></tr>
 189 <tr><td>G</td><td>16</td><td>0</td><td>13</td><td>7</td><td>4</td><td>9</td><td>12</td><td>6</td><td>9</td><td>7</td><td>9</td><td>10</td><td>9</td><td>9</td><td>6</td><td>4</td><td>12</td><td>9</td><td>3</td><td>12</td><td>8</td><td>3</td><td>8</td><td>0</td></tr>
 190 <tr><td>H</td><td>6</td><td>0</td><td>7</td><td>9</td><td>10</td><td>11</td><td>6</td><td>17</td><td>7</td><td>17</td><td>7</td><td>8</td><td>7</td><td>3</td><td>8</td><td>14</td><td>6</td><td>7</td><td>6</td><td>6</td><td>14</td><td>6</td><td>14</td><td>0</td></tr>
 191 <tr><td>I</td><td>9</td><td>0</td><td>10</td><td>4</td><td>5</td><td>10</td><td>9</td><td>7</td><td>14</td><td>8</td><td>14</td><td>11</td><td>6</td><td>6</td><td>7</td><td>5</td><td>5</td><td>6</td><td>3</td><td>13</td><td>9</td><td>3</td><td>9</td><td>0</td></tr>
 192 <tr><td>K</td><td>7</td><td>0</td><td>8</td><td>10</td><td>11</td><td>8</td><td>7</td><td>17</td><td>8</td><td>11</td><td>8</td><td>9</td><td>8</td><td>4</td><td>9</td><td>15</td><td>7</td><td>8</td><td>6</td><td>7</td><td>11</td><td>6</td><td>11</td><td>0</td></tr>
 193 <tr><td>L</td><td>9</td><td>0</td><td>10</td><td>4</td><td>5</td><td>10</td><td>9</td><td>7</td><td>14</td><td>8</td><td>13</td><td>11</td><td>6</td><td>6</td><td>7</td><td>5</td><td>5</td><td>6</td><td>3</td><td>13</td><td>9</td><td>3</td><td>9</td><td>0</td></tr>
 194 <tr><td>M</td><td>10</td><td>0</td><td>11</td><td>5</td><td>6</td><td>11</td><td>10</td><td>8</td><td>11</td><td>9</td><td>11</td><td>11</td><td>7</td><td>7</td><td>8</td><td>6</td><td>6</td><td>7</td><td>3</td><td>10</td><td>10</td><td>3</td><td>10</td><td>0</td></tr>
 195 <tr><td>N</td><td>9</td><td>0</td><td>10</td><td>12</td><td>9</td><td>6</td><td>9</td><td>7</td><td>6</td><td>8</td><td>6</td><td>7</td><td>14</td><td>10</td><td>11</td><td>9</td><td>13</td><td>14</td><td>3</td><td>9</td><td>9</td><td>3</td><td>9</td><td>0</td></tr>
 196 <tr><td>P</td><td>9</td><td>0</td><td>10</td><td>8</td><td>5</td><td>6</td><td>9</td><td>3</td><td>6</td><td>4</td><td>6</td><td>7</td><td>10</td><td>10</td><td>7</td><td>5</td><td>9</td><td>10</td><td>0</td><td>9</td><td>5</td><td>0</td><td>5</td><td>0</td></tr>
 197 <tr><td>Q</td><td>6</td><td>0</td><td>7</td><td>9</td><td>10</td><td>7</td><td>6</td><td>8</td><td>7</td><td>9</td><td>7</td><td>8</td><td>11</td><td>7</td><td>11</td><td>10</td><td>10</td><td>11</td><td>3</td><td>6</td><td>10</td><td>3</td><td>10</td><td>0</td></tr>
 198 <tr><td>R</td><td>4</td><td>0</td><td>5</td><td>11</td><td>12</td><td>5</td><td>4</td><td>14</td><td>5</td><td>15</td><td>5</td><td>6</td><td>9</td><td>5</td><td>10</td><td>15</td><td>8</td><td>9</td><td>3</td><td>4</td><td>8</td><td>3</td><td>8</td><td>0</td></tr>
 199 <tr><td>S</td><td>12</td><td>0</td><td>9</td><td>11</td><td>8</td><td>5</td><td>12</td><td>6</td><td>5</td><td>7</td><td>5</td><td>6</td><td>13</td><td>9</td><td>10</td><td>8</td><td>13</td><td>13</td><td>3</td><td>8</td><td>8</td><td>3</td><td>8</td><td>0</td></tr>
 200 <tr><td>T</td><td>9</td><td>0</td><td>10</td><td>12</td><td>9</td><td>6</td><td>9</td><td>7</td><td>6</td><td>8</td><td>6</td><td>7</td><td>14</td><td>10</td><td>11</td><td>9</td><td>13</td><td>9</td><td>3</td><td>9</td><td>9</td><td>3</td><td>9</td><td>0</td></tr>
 201 <tr><td>U</td><td>3</td><td>0</td><td>3</td><td>3</td><td>3</td><td>3</td><td>3</td><td>6</td><td>3</td><td>6</td><td>3</td><td>3</td><td>3</td><td>0</td><td>3</td><td>3</td><td>3</td><td>3</td><td>0</td><td>3</td><td>6</td><td>0</td><td>6</td><td>0</td></tr>
 202 <tr><td>V</td><td>12</td><td>0</td><td>13</td><td>7</td><td>4</td><td>9</td><td>12</td><td>6</td><td>13</td><td>7</td><td>13</td><td>10</td><td>9</td><td>9</td><td>6</td><td>4</td><td>8</td><td>9</td><td>3</td><td>3</td><td>8</td><td>3</td><td>8</td><td>0</td></tr>
 203 <tr><td>W</td><td>8</td><td>0</td><td>9</td><td>7</td><td>8</td><td>13</td><td>8</td><td>14</td><td>9</td><td>11</td><td>9</td><td>10</td><td>9</td><td>5</td><td>10</td><td>8</td><td>8</td><td>9</td><td>6</td><td>8</td><td>16</td><td>6</td><td>16</td><td>0</td></tr>
 204 <tr><td>X</td><td>3</td><td>0</td><td>3</td><td>3</td><td>3</td><td>3</td><td>3</td><td>6</td><td>3</td><td>6</td><td>3</td><td>3</td><td>3</td><td>0</td><td>3</td><td>3</td><td>3</td><td>3</td><td>0</td><td>3</td><td>6</td><td>0</td><td>6</td><td>0</td></tr>
 205 <tr><td>Y</td><td>8</td><td>0</td><td>9</td><td>7</td><td>8</td><td>13</td><td>8</td><td>14</td><td>9</td><td>11</td><td>9</td><td>10</td><td>9</td><td>5</td><td>10</td><td>8</td><td>8</td><td>9</td><td>6</td><td>8</td><td>16</td><td>6</td><td>8</td><td>0</td></tr>
 206 <tr><td>Z</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>
 207 </table>
 208
 209
 210 </li> -->
 211 </ul>
 212                 </body>
 213 </html>