JAL-1620 version bump and release notes
[jalview.git] / src / jalview / bin / JalviewLite.java
old mode 100755 (executable)
new mode 100644 (file)
index 4d1c216..dcd3261
 /*
- * Jalview - A Sequence Alignment Editor and Viewer
- * Copyright (C) 2007 AM Waterhouse, J Procter, G Barton, M Clamp, S Searle
- *
- * This program is free software; you can redistribute it and/or
- * modify it under the terms of the GNU General Public License
- * as published by the Free Software Foundation; either version 2
+ * Jalview - A Sequence Alignment Editor and Viewer (Version 2.8.2b1)
+ * Copyright (C) 2014 The Jalview Authors
+ * 
+ * This file is part of Jalview.
+ * 
+ * Jalview is free software: you can redistribute it and/or
+ * modify it under the terms of the GNU General Public License 
+ * as published by the Free Software Foundation, either version 3
  * of the License, or (at your option) any later version.
- *
- * This program is distributed in the hope that it will be useful,
- * but WITHOUT ANY WARRANTY; without even the implied warranty of
- * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
- * GNU General Public License for more details.
- *
+ *  
+ * Jalview is distributed in the hope that it will be useful, but 
+ * WITHOUT ANY WARRANTY; without even the implied warranty 
+ * of MERCHANTABILITY or FITNESS FOR A PARTICULAR 
+ * PURPOSE.  See the GNU General Public License for more details.
+ * 
  * You should have received a copy of the GNU General Public License
- * along with this program; if not, write to the Free Software
- * Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA  02110-1301, USA
+ * along with Jalview.  If not, see <http://www.gnu.org/licenses/>.
+ * The Jalview Authors are detailed in the 'AUTHORS' file.
  */
 package jalview.bin;
 
-import java.applet.*;
-
-import java.awt.*;
-import java.awt.event.*;
-import java.util.*;
-
-import jalview.appletgui.*;
-import jalview.datamodel.*;
-import jalview.io.*;
+import jalview.api.StructureSelectionManagerProvider;
+import jalview.appletgui.AlignFrame;
+import jalview.appletgui.AlignViewport;
+import jalview.appletgui.EmbmenuFrame;
+import jalview.appletgui.FeatureSettings;
+import jalview.datamodel.Alignment;
+import jalview.datamodel.AlignmentI;
+import jalview.datamodel.AlignmentOrder;
+import jalview.datamodel.ColumnSelection;
+import jalview.datamodel.PDBEntry;
+import jalview.datamodel.Sequence;
+import jalview.datamodel.SequenceGroup;
+import jalview.datamodel.SequenceI;
+import jalview.io.AnnotationFile;
+import jalview.io.AppletFormatAdapter;
+import jalview.io.FileParse;
+import jalview.io.IdentifyFile;
+import jalview.io.JnetAnnotationMaker;
+import jalview.javascript.JSFunctionExec;
+import jalview.javascript.JalviewLiteJsApi;
+import jalview.javascript.JsCallBack;
+import jalview.structure.SelectionListener;
+import jalview.structure.StructureSelectionManager;
+import jalview.util.MessageManager;
+
+import java.applet.Applet;
+import java.awt.Button;
+import java.awt.Color;
+import java.awt.Component;
+import java.awt.EventQueue;
+import java.awt.Font;
+import java.awt.Frame;
+import java.awt.Graphics;
+import java.awt.event.ActionEvent;
+import java.awt.event.WindowAdapter;
+import java.awt.event.WindowEvent;
+import java.io.BufferedReader;
+import java.io.InputStreamReader;
+import java.net.URL;
+import java.util.Hashtable;
+import java.util.StringTokenizer;
+import java.util.Vector;
+
+import netscape.javascript.JSException;
+import netscape.javascript.JSObject;
 
 /**
  * Jalview Applet. Runs in Java 1.18 runtime
- *
+ * 
  * @author $author$
- * @version $Revision$
+ * @version $Revision: 1.92 $
  */
-public class JalviewLite
-    extends Applet
+public class JalviewLite extends Applet implements
+        StructureSelectionManagerProvider, JalviewLiteJsApi
 {
 
+  public StructureSelectionManager getStructureSelectionManager()
+  {
+    return StructureSelectionManager.getStructureSelectionManager(this);
+  }
 
-
-  ///////////////////////////////////////////
-  //The following public methods maybe called
-  //externally, eg via javascript in HTML page
-  /**
-   * @return list of selected sequences separated by "¬"
+  // /////////////////////////////////////////
+  // The following public methods maybe called
+  // externally, eg via javascript in HTML page
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getSelectedSequences()
    */
   public String getSelectedSequences()
   {
-    return getSelectedSequences(currentAlignFrame);
+    return getSelectedSequencesFrom(getDefaultTargetFrame());
   }
-  public String getSelectedSequences(AlignFrame alf)
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getSelectedSequences(java.lang.String)
+   */
+  public String getSelectedSequences(String sep)
   {
-    StringBuffer result = new StringBuffer("");
+    return getSelectedSequencesFrom(getDefaultTargetFrame(), sep);
+  }
 
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getSelectedSequencesFrom(jalview.appletgui
+   * .AlignFrame)
+   */
+  public String getSelectedSequencesFrom(AlignFrame alf)
+  {
+    return getSelectedSequencesFrom(alf, separator); // ""+0x00AC);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getSelectedSequencesFrom(jalview.appletgui
+   * .AlignFrame, java.lang.String)
+   */
+  public String getSelectedSequencesFrom(AlignFrame alf, String sep)
+  {
+    StringBuffer result = new StringBuffer("");
+    if (sep == null || sep.length() == 0)
+    {
+      sep = separator; // "+0x00AC;
+    }
     if (alf.viewport.getSelectionGroup() != null)
     {
-      SequenceI[] seqs = alf.viewport.getSelectionGroup().
-          getSequencesInOrder(
-                  alf.viewport.getAlignment());
+      SequenceI[] seqs = alf.viewport.getSelectionGroup()
+              .getSequencesInOrder(alf.viewport.getAlignment());
 
       for (int i = 0; i < seqs.length; i++)
       {
-        result.append(seqs[i].getName() + "¬");
+        result.append(seqs[i].getName());
+        result.append(sep);
       }
     }
 
     return result.toString();
   }
-  
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#highlight(java.lang.String,
+   * java.lang.String, java.lang.String)
+   */
+  public void highlight(String sequenceId, String position,
+          String alignedPosition)
+  {
+    highlightIn(getDefaultTargetFrame(), sequenceId, position,
+            alignedPosition);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#highlightIn(jalview.appletgui.AlignFrame,
+   * java.lang.String, java.lang.String, java.lang.String)
+   */
+  public void highlightIn(final AlignFrame alf, final String sequenceId,
+          final String position, final String alignedPosition)
+  {
+    // TODO: could try to highlight in all alignments if alf==null
+    jalview.analysis.SequenceIdMatcher matcher = new jalview.analysis.SequenceIdMatcher(
+            alf.viewport.getAlignment().getSequencesArray());
+    final SequenceI sq = matcher.findIdMatch(sequenceId);
+    if (sq != null)
+    {
+      int apos = -1;
+      try
+      {
+        apos = new Integer(position).intValue();
+        apos--;
+      } catch (NumberFormatException ex)
+      {
+        return;
+      }
+      final StructureSelectionManagerProvider me = this;
+      final int pos = apos;
+      // use vamsas listener to broadcast to all listeners in scope
+      if (alignedPosition != null
+              && (alignedPosition.trim().length() == 0 || alignedPosition
+                      .toLowerCase().indexOf("false") > -1))
+      {
+        java.awt.EventQueue.invokeLater(new Runnable()
+        {
+          @Override
+          public void run()
+          {
+            StructureSelectionManager.getStructureSelectionManager(me)
+                    .mouseOverVamsasSequence(sq, sq.findIndex(pos), null);
+          }
+        });
+      }
+      else
+      {
+        java.awt.EventQueue.invokeLater(new Runnable()
+        {
+          @Override
+          public void run()
+          {
+            StructureSelectionManager.getStructureSelectionManager(me)
+                    .mouseOverVamsasSequence(sq, pos, null);
+          }
+        });
+      }
+    }
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#select(java.lang.String,
+   * java.lang.String)
+   */
+  public void select(String sequenceIds, String columns)
+  {
+    selectIn(getDefaultTargetFrame(), sequenceIds, columns, separator);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#select(java.lang.String,
+   * java.lang.String, java.lang.String)
+   */
+  public void select(String sequenceIds, String columns, String sep)
+  {
+    selectIn(getDefaultTargetFrame(), sequenceIds, columns, sep);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#selectIn(jalview.appletgui.AlignFrame,
+   * java.lang.String, java.lang.String)
+   */
+  public void selectIn(AlignFrame alf, String sequenceIds, String columns)
+  {
+    selectIn(alf, sequenceIds, columns, separator);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#selectIn(jalview.appletgui.AlignFrame,
+   * java.lang.String, java.lang.String, java.lang.String)
+   */
+  public void selectIn(final AlignFrame alf, String sequenceIds,
+          String columns, String sep)
+  {
+    if (sep == null || sep.length() == 0)
+    {
+      sep = separator;
+    }
+    else
+    {
+      if (debug)
+      {
+        System.err.println("Selecting region using separator string '"
+                + separator + "'");
+      }
+    }
+    // deparse fields
+    String[] ids = separatorListToArray(sequenceIds, sep);
+    String[] cols = separatorListToArray(columns, sep);
+    final SequenceGroup sel = new SequenceGroup();
+    final ColumnSelection csel = new ColumnSelection();
+    AlignmentI al = alf.viewport.getAlignment();
+    jalview.analysis.SequenceIdMatcher matcher = new jalview.analysis.SequenceIdMatcher(
+            alf.viewport.getAlignment().getSequencesArray());
+    int start = 0, end = al.getWidth(), alw = al.getWidth();
+    boolean seqsfound = true;
+    if (ids != null && ids.length > 0)
+    {
+      seqsfound = false;
+      for (int i = 0; i < ids.length; i++)
+      {
+        if (ids[i].trim().length() == 0)
+        {
+          continue;
+        }
+        SequenceI sq = matcher.findIdMatch(ids[i]);
+        if (sq != null)
+        {
+          seqsfound = true;
+          sel.addSequence(sq, false);
+        }
+      }
+    }
+    boolean inseqpos = false;
+    if (cols != null && cols.length > 0)
+    {
+      boolean seset = false;
+      for (int i = 0; i < cols.length; i++)
+      {
+        String cl = cols[i].trim();
+        if (cl.length() == 0)
+        {
+          continue;
+        }
+        int p;
+        if ((p = cl.indexOf("-")) > -1)
+        {
+          int from = -1, to = -1;
+          try
+          {
+            from = new Integer(cl.substring(0, p)).intValue();
+            from--;
+          } catch (NumberFormatException ex)
+          {
+            System.err
+                    .println("ERROR: Couldn't parse first integer in range element column selection string '"
+                            + cl + "' - format is 'from-to'");
+            return;
+          }
+          try
+          {
+            to = new Integer(cl.substring(p + 1)).intValue();
+            to--;
+          } catch (NumberFormatException ex)
+          {
+            System.err
+                    .println("ERROR: Couldn't parse second integer in range element column selection string '"
+                            + cl + "' - format is 'from-to'");
+            return;
+          }
+          if (from >= 0 && to >= 0)
+          {
+            // valid range
+            if (from < to)
+            {
+              int t = to;
+              to = from;
+              to = t;
+            }
+            if (!seset)
+            {
+              start = from;
+              end = to;
+              seset = true;
+            }
+            else
+            {
+              // comment to prevent range extension
+              if (start > from)
+              {
+                start = from;
+              }
+              if (end < to)
+              {
+                end = to;
+              }
+            }
+            for (int r = from; r <= to; r++)
+            {
+              if (r >= 0 && r < alw)
+              {
+                csel.addElement(r);
+              }
+            }
+            if (debug)
+            {
+              System.err.println("Range '" + cl + "' deparsed as [" + from
+                      + "," + to + "]");
+            }
+          }
+          else
+          {
+            System.err.println("ERROR: Invalid Range '" + cl
+                    + "' deparsed as [" + from + "," + to + "]");
+          }
+        }
+        else
+        {
+          int r = -1;
+          try
+          {
+            r = new Integer(cl).intValue();
+            r--;
+          } catch (NumberFormatException ex)
+          {
+            if (cl.toLowerCase().equals("sequence"))
+            {
+              // we are in the dataset sequence's coordinate frame.
+              inseqpos = true;
+            }
+            else
+            {
+              System.err
+                      .println("ERROR: Couldn't parse integer from point selection element of column selection string '"
+                              + cl + "'");
+              return;
+            }
+          }
+          if (r >= 0 && r <= alw)
+          {
+            if (!seset)
+            {
+              start = r;
+              end = r;
+              seset = true;
+            }
+            else
+            {
+              // comment to prevent range extension
+              if (start > r)
+              {
+                start = r;
+              }
+              if (end < r)
+              {
+                end = r;
+              }
+            }
+            csel.addElement(r);
+            if (debug)
+            {
+              System.err.println("Point selection '" + cl
+                      + "' deparsed as [" + r + "]");
+            }
+          }
+          else
+          {
+            System.err.println("ERROR: Invalid Point selection '" + cl
+                    + "' deparsed as [" + r + "]");
+          }
+        }
+      }
+    }
+    if (seqsfound)
+    {
+      // we only propagate the selection when it was the null selection, or the
+      // given sequences were found in the alignment.
+      if (inseqpos && sel.getSize() > 0)
+      {
+        // assume first sequence provides reference frame ?
+        SequenceI rs = sel.getSequenceAt(0);
+        start = rs.findIndex(start);
+        end = rs.findIndex(end);
+        if (csel != null)
+        {
+          Vector cs = csel.getSelected();
+          csel.clear();
+          for (int csi = 0, csiS = cs.size(); csi < csiS; csi++)
+          {
+            csel.addElement(rs.findIndex(((Integer) cs.elementAt(csi))
+                    .intValue()));
+          }
+        }
+      }
+      sel.setStartRes(start);
+      sel.setEndRes(end);
+      EventQueue.invokeLater(new Runnable()
+      {
+        @Override
+        public void run()
+        {
+          alf.select(sel, csel);
+        }
+      });
+    }
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getSelectedSequencesAsAlignment(java.lang.
+   * String, java.lang.String)
+   */
+  public String getSelectedSequencesAsAlignment(String format, String suffix)
+  {
+    return getSelectedSequencesAsAlignmentFrom(getDefaultTargetFrame(),
+            format, suffix);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getSelectedSequencesAsAlignmentFrom(jalview
+   * .appletgui.AlignFrame, java.lang.String, java.lang.String)
+   */
+  public String getSelectedSequencesAsAlignmentFrom(AlignFrame alf,
+          String format, String suffix)
+  {
+    try
+    {
+      boolean seqlimits = suffix.equalsIgnoreCase("true");
+      if (alf.viewport.getSelectionGroup() != null)
+      {
+        // JBPNote: getSelectionAsNewSequence behaviour has changed - this
+        // method now returns a full copy of sequence data
+        // TODO consider using getSequenceSelection instead here
+        String reply = new AppletFormatAdapter().formatSequences(format,
+                new Alignment(alf.viewport.getSelectionAsNewSequence()),
+                seqlimits);
+        return reply;
+      }
+    } catch (Exception ex)
+    {
+      ex.printStackTrace();
+      return "Error retrieving alignment in " + format + " format. ";
+    }
+    return "";
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getAlignmentOrder()
+   */
+  public String getAlignmentOrder()
+  {
+    return getAlignmentOrderFrom(getDefaultTargetFrame());
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getAlignmentOrderFrom(jalview.appletgui.AlignFrame
+   * )
+   */
+  public String getAlignmentOrderFrom(AlignFrame alf)
+  {
+    return getAlignmentOrderFrom(alf, separator);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getAlignmentOrderFrom(jalview.appletgui.AlignFrame
+   * , java.lang.String)
+   */
+  public String getAlignmentOrderFrom(AlignFrame alf, String sep)
+  {
+    AlignmentI alorder = alf.getAlignViewport().getAlignment();
+    String[] order = new String[alorder.getHeight()];
+    for (int i = 0; i < order.length; i++)
+    {
+      order[i] = alorder.getSequenceAt(i).getName();
+    }
+    return arrayToSeparatorList(order);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#orderBy(java.lang.String,
+   * java.lang.String)
+   */
+  public String orderBy(String order, String undoName)
+  {
+    return orderBy(order, undoName, separator);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#orderBy(java.lang.String,
+   * java.lang.String, java.lang.String)
+   */
+  public String orderBy(String order, String undoName, String sep)
+  {
+    return orderAlignmentBy(getDefaultTargetFrame(), order, undoName, sep);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#orderAlignmentBy(jalview.appletgui.AlignFrame,
+   * java.lang.String, java.lang.String, java.lang.String)
+   */
+  public String orderAlignmentBy(AlignFrame alf, String order,
+          String undoName, String sep)
+  {
+    String[] ids = separatorListToArray(order, sep);
+    SequenceI[] sqs = null;
+    if (ids != null && ids.length > 0)
+    {
+      jalview.analysis.SequenceIdMatcher matcher = new jalview.analysis.SequenceIdMatcher(
+              alf.viewport.getAlignment().getSequencesArray());
+      int s = 0;
+      sqs = new SequenceI[ids.length];
+      for (int i = 0; i < ids.length; i++)
+      {
+        if (ids[i].trim().length() == 0)
+        {
+          continue;
+        }
+        SequenceI sq = matcher.findIdMatch(ids[i]);
+        if (sq != null)
+        {
+          sqs[s++] = sq;
+        }
+      }
+      if (s > 0)
+      {
+        SequenceI[] sqq = new SequenceI[s];
+        System.arraycopy(sqs, 0, sqq, 0, s);
+        sqs = sqq;
+      }
+      else
+      {
+        sqs = null;
+      }
+    }
+    if (sqs == null)
+    {
+      return "";
+    }
+    ;
+    final AlignmentOrder aorder = new AlignmentOrder(sqs);
+
+    if (undoName != null && undoName.trim().length() == 0)
+    {
+      undoName = null;
+    }
+    final String _undoName = undoName;
+    // TODO: deal with synchronization here: cannot raise any events until after
+    // this has returned.
+    return alf.sortBy(aorder, _undoName) ? "true" : "";
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getAlignment(java.lang.String)
+   */
   public String getAlignment(String format)
   {
-    return getAlignment(currentAlignFrame, format, "true");
+    return getAlignmentFrom(getDefaultTargetFrame(), format, "true");
   }
-  public String getAlignment(AlignFrame alf, String format)
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getAlignmentFrom(jalview.appletgui.AlignFrame,
+   * java.lang.String)
+   */
+  public String getAlignmentFrom(AlignFrame alf, String format)
   {
-    return getAlignment(alf, format, "true");
+    return getAlignmentFrom(alf, format, "true");
   }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getAlignment(java.lang.String,
+   * java.lang.String)
+   */
   public String getAlignment(String format, String suffix)
   {
-    return getAlignment(currentAlignFrame, format, suffix);
+    return getAlignmentFrom(getDefaultTargetFrame(), format, suffix);
   }
-  public String getAlignment(AlignFrame alf, String format, String suffix)
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getAlignmentFrom(jalview.appletgui.AlignFrame,
+   * java.lang.String, java.lang.String)
+   */
+  public String getAlignmentFrom(AlignFrame alf, String format,
+          String suffix)
   {
     try
     {
       boolean seqlimits = suffix.equalsIgnoreCase("true");
 
       String reply = new AppletFormatAdapter().formatSequences(format,
-          alf.viewport.getAlignment(), seqlimits);
+              alf.viewport.getAlignment(), seqlimits);
       return reply;
-    }
-    catch (Exception ex)
+    } catch (Exception ex)
     {
       ex.printStackTrace();
       return "Error retrieving alignment in " + format + " format. ";
     }
   }
 
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#loadAnnotation(java.lang.String)
+   */
   public void loadAnnotation(String annotation)
   {
-    loadAnnotation(currentAlignFrame, annotation);
+    loadAnnotationFrom(getDefaultTargetFrame(), annotation);
   }
-  public void loadAnnotation(AlignFrame alf, String annotation)
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#loadAnnotationFrom(jalview.appletgui.AlignFrame
+   * , java.lang.String)
+   */
+  public void loadAnnotationFrom(AlignFrame alf, String annotation)
   {
-    if (new AnnotationFile().readAnnotationFile(
-        alf.getAlignViewport().getAlignment(), annotation,
-        AppletFormatAdapter.PASTE))
+    if (new AnnotationFile().readAnnotationFile(alf.getAlignViewport()
+            .getAlignment(), annotation, AppletFormatAdapter.PASTE))
     {
       alf.alignPanel.fontChanged();
       alf.alignPanel.setScrollValues(0, 0);
@@ -117,93 +721,692 @@ public class JalviewLite
     }
   }
 
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#loadAnnotation(java.lang.String)
+   */
+  public void loadFeatures(String features, boolean autoenabledisplay)
+  {
+    loadFeaturesFrom(getDefaultTargetFrame(), features, autoenabledisplay);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#loadAnnotationFrom(jalview.appletgui.AlignFrame
+   * , java.lang.String)
+   */
+  public boolean loadFeaturesFrom(AlignFrame alf, String features,
+          boolean autoenabledisplay)
+  {
+    return alf.parseFeaturesFile(features, AppletFormatAdapter.PASTE,
+            autoenabledisplay);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getFeatures(java.lang.String)
+   */
   public String getFeatures(String format)
   {
-    return getFeatures(currentAlignFrame, format);
+    return getFeaturesFrom(getDefaultTargetFrame(), format);
   }
-  public String getFeatures(AlignFrame alf, String format)
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getFeaturesFrom(jalview.appletgui.AlignFrame,
+   * java.lang.String)
+   */
+  public String getFeaturesFrom(AlignFrame alf, String format)
   {
     return alf.outputFeatures(false, format);
   }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getAnnotation()
+   */
   public String getAnnotation()
   {
-    return getAnnotation(currentAlignFrame);
+    return getAnnotationFrom(getDefaultTargetFrame());
   }
-  public String getAnnotation(AlignFrame alf)
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getAnnotationFrom(jalview.appletgui.AlignFrame
+   * )
+   */
+  public String getAnnotationFrom(AlignFrame alf)
   {
     return alf.outputAnnotations(false);
   }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#newView()
+   */
   public AlignFrame newView()
   {
-    return newView(currentAlignFrame);
+    return newViewFrom(getDefaultTargetFrame());
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#newView(java.lang.String)
+   */
+  public AlignFrame newView(String name)
+  {
+    return newViewFrom(getDefaultTargetFrame(), name);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#newViewFrom(jalview.appletgui.AlignFrame)
+   */
+  public AlignFrame newViewFrom(AlignFrame alf)
+  {
+    return alf.newView(null);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#newViewFrom(jalview.appletgui.AlignFrame,
+   * java.lang.String)
+   */
+  public AlignFrame newViewFrom(AlignFrame alf, String name)
+  {
+    return alf.newView(name);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#loadAlignment(java.lang.String,
+   * java.lang.String)
+   */
+  public AlignFrame loadAlignment(String text, String title)
+  {
+    Alignment al = null;
+
+    String format = new IdentifyFile().Identify(text,
+            AppletFormatAdapter.PASTE);
+    try
+    {
+      al = new AppletFormatAdapter().readFile(text,
+              AppletFormatAdapter.PASTE, format);
+      if (al.getHeight() > 0)
+      {
+        return new AlignFrame(al, this, title, false);
+      }
+    } catch (java.io.IOException ex)
+    {
+      ex.printStackTrace();
+    }
+    return null;
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#setMouseoverListener(java.lang.String)
+   */
+  public void setMouseoverListener(String listener)
+  {
+    setMouseoverListener(currentAlignFrame, listener);
+  }
+
+  private Vector<jalview.javascript.JSFunctionExec> javascriptListeners = new Vector<jalview.javascript.JSFunctionExec>();
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#setMouseoverListener(jalview.appletgui.AlignFrame
+   * , java.lang.String)
+   */
+  public void setMouseoverListener(AlignFrame af, String listener)
+  {
+    if (listener != null)
+    {
+      listener = listener.trim();
+      if (listener.length() == 0)
+      {
+        System.err
+                .println("jalview Javascript error: Ignoring empty function for mouseover listener.");
+        return;
+      }
+    }
+    jalview.javascript.MouseOverListener mol = new jalview.javascript.MouseOverListener(
+            this, af, listener);
+    javascriptListeners.addElement(mol);
+    StructureSelectionManager.getStructureSelectionManager(this)
+            .addStructureViewerListener(mol);
+    if (debug)
+    {
+      System.err.println("Added a mouseover listener for "
+              + ((af == null) ? "All frames" : "Just views for "
+                      + af.getAlignViewport().getSequenceSetId()));
+      System.err.println("There are now " + javascriptListeners.size()
+              + " listeners in total.");
+    }
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#setSelectionListener(java.lang.String)
+   */
+  public void setSelectionListener(String listener)
+  {
+    setSelectionListener(null, listener);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#setSelectionListener(jalview.appletgui.AlignFrame
+   * , java.lang.String)
+   */
+  public void setSelectionListener(AlignFrame af, String listener)
+  {
+    if (listener != null)
+    {
+      listener = listener.trim();
+      if (listener.length() == 0)
+      {
+        System.err
+                .println("jalview Javascript error: Ignoring empty function for selection listener.");
+        return;
+      }
+    }
+    jalview.javascript.JsSelectionSender mol = new jalview.javascript.JsSelectionSender(
+            this, af, listener);
+    javascriptListeners.addElement(mol);
+    StructureSelectionManager.getStructureSelectionManager(this)
+            .addSelectionListener(mol);
+    if (debug)
+    {
+      System.err.println("Added a selection listener for "
+              + ((af == null) ? "All frames" : "Just views for "
+                      + af.getAlignViewport().getSequenceSetId()));
+      System.err.println("There are now " + javascriptListeners.size()
+              + " listeners in total.");
+    }
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#setStructureListener(java.lang.String,
+   * java.lang.String)
+   */
+  public void setStructureListener(String listener, String modelSet)
+  {
+    if (listener != null)
+    {
+      listener = listener.trim();
+      if (listener.length() == 0)
+      {
+        System.err
+                .println("jalview Javascript error: Ignoring empty function for selection listener.");
+        return;
+      }
+    }
+    jalview.javascript.MouseOverStructureListener mol = new jalview.javascript.MouseOverStructureListener(
+            this, listener, separatorListToArray(modelSet));
+    javascriptListeners.addElement(mol);
+    StructureSelectionManager.getStructureSelectionManager(this)
+            .addStructureViewerListener(mol);
+    if (debug)
+    {
+      System.err.println("Added a javascript structure viewer listener '"
+              + listener + "'");
+      System.err.println("There are now " + javascriptListeners.size()
+              + " listeners in total.");
+    }
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#removeJavascriptListener(jalview.appletgui
+   * .AlignFrame, java.lang.String)
+   */
+  public void removeJavascriptListener(AlignFrame af, String listener)
+  {
+    if (listener != null)
+    {
+      listener = listener.trim();
+      if (listener.length() == 0)
+      {
+        listener = null;
+      }
+    }
+    boolean rprt = false;
+    for (int ms = 0, msSize = javascriptListeners.size(); ms < msSize;)
+    {
+      Object lstn = javascriptListeners.elementAt(ms);
+      JsCallBack lstner = (JsCallBack) lstn;
+      if ((af == null || lstner.getAlignFrame() == af)
+              && (listener == null || lstner.getListenerFunction().equals(
+                      listener)))
+      {
+        javascriptListeners.removeElement(lstner);
+        msSize--;
+        if (lstner instanceof SelectionListener)
+        {
+          StructureSelectionManager.getStructureSelectionManager(this)
+                  .removeSelectionListener((SelectionListener) lstner);
+        }
+        else
+        {
+          StructureSelectionManager.getStructureSelectionManager(this)
+                  .removeStructureViewerListener(lstner, null);
+        }
+        rprt = debug;
+        if (debug)
+        {
+          System.err.println("Removed listener '" + listener + "'");
+        }
+      }
+      else
+      {
+        ms++;
+      }
+    }
+    if (rprt)
+    {
+      System.err.println("There are now " + javascriptListeners.size()
+              + " listeners in total.");
+    }
+  }
+
+  public void stop()
+  {
+    System.err.println("Applet " + getName() + " stop().");
+    tidyUp();
+  }
+
+  public void destroy()
+  {
+    System.err.println("Applet " + getName() + " destroy().");
+    tidyUp();
+  }
+
+  private void tidyUp()
+  {
+    removeAll();
+    if (currentAlignFrame != null && currentAlignFrame.viewport != null
+            && currentAlignFrame.viewport.applet != null)
+    {
+      AlignViewport av = currentAlignFrame.viewport;
+      currentAlignFrame.closeMenuItem_actionPerformed();
+      av.applet = null;
+      currentAlignFrame = null;
+    }
+    if (javascriptListeners != null)
+    {
+      while (javascriptListeners.size() > 0)
+      {
+        jalview.javascript.JSFunctionExec mol = javascriptListeners
+                .elementAt(0);
+        javascriptListeners.removeElement(mol);
+        if (mol instanceof SelectionListener)
+        {
+          StructureSelectionManager.getStructureSelectionManager(this)
+                  .removeSelectionListener((SelectionListener) mol);
+        }
+        else
+        {
+          StructureSelectionManager.getStructureSelectionManager(this)
+                  .removeStructureViewerListener(mol, null);
+        }
+        mol.jvlite = null;
+      }
+    }
+    if (jsFunctionExec != null)
+    {
+      jsFunctionExec.stopQueue();
+      jsFunctionExec.jvlite = null;
+    }
+    initialAlignFrame = null;
+    jsFunctionExec = null;
+    javascriptListeners = null;
+    StructureSelectionManager.release(this);
+  }
+
+  private jalview.javascript.JSFunctionExec jsFunctionExec;
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#mouseOverStructure(java.lang.String,
+   * java.lang.String, java.lang.String)
+   */
+  public void mouseOverStructure(final String pdbResNum,
+          final String chain, final String pdbfile)
+  {
+    final StructureSelectionManagerProvider me = this;
+    java.awt.EventQueue.invokeLater(new Runnable()
+    {
+      @Override
+      public void run()
+      {
+        try
+        {
+          StructureSelectionManager.getStructureSelectionManager(me)
+                  .mouseOverStructure(new Integer(pdbResNum).intValue(),
+                          chain, pdbfile);
+          if (debug)
+          {
+            System.err.println("mouseOver for '" + pdbResNum
+                    + "' in chain '" + chain + "' in structure '" + pdbfile
+                    + "'");
+          }
+        } catch (NumberFormatException e)
+        {
+          System.err.println("Ignoring invalid residue number string '"
+                  + pdbResNum + "'");
+        }
+
+      }
+    });
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#scrollViewToIn(jalview.appletgui.AlignFrame,
+   * java.lang.String, java.lang.String)
+   */
+  public void scrollViewToIn(final AlignFrame alf, final String topRow,
+          final String leftHandColumn)
+  {
+    java.awt.EventQueue.invokeLater(new Runnable()
+    {
+      @Override
+      public void run()
+      {
+        try
+        {
+          alf.scrollTo(new Integer(topRow).intValue(), new Integer(
+                  leftHandColumn).intValue());
+
+        } catch (Exception ex)
+        {
+          System.err.println("Couldn't parse integer arguments (topRow='"
+                  + topRow + "' and leftHandColumn='" + leftHandColumn
+                  + "')");
+          ex.printStackTrace();
+        }
+      }
+    });
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.javascript.JalviewLiteJsApi#scrollViewToRowIn(jalview.appletgui
+   * .AlignFrame, java.lang.String)
+   */
+  @Override
+  public void scrollViewToRowIn(final AlignFrame alf, final String topRow)
+  {
+
+    java.awt.EventQueue.invokeLater(new Runnable()
+    {
+      @Override
+      public void run()
+      {
+        try
+        {
+          alf.scrollToRow(new Integer(topRow).intValue());
+
+        } catch (Exception ex)
+        {
+          System.err.println("Couldn't parse integer arguments (topRow='"
+                  + topRow + "')");
+          ex.printStackTrace();
+        }
+
+      }
+    });
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.javascript.JalviewLiteJsApi#scrollViewToColumnIn(jalview.appletgui
+   * .AlignFrame, java.lang.String)
+   */
+  @Override
+  public void scrollViewToColumnIn(final AlignFrame alf,
+          final String leftHandColumn)
+  {
+    java.awt.EventQueue.invokeLater(new Runnable()
+    {
+
+      @Override
+      public void run()
+      {
+        try
+        {
+          alf.scrollToColumn(new Integer(leftHandColumn).intValue());
+
+        } catch (Exception ex)
+        {
+          System.err
+                  .println("Couldn't parse integer arguments (leftHandColumn='"
+                          + leftHandColumn + "')");
+          ex.printStackTrace();
+        }
+      }
+    });
+
+  }
+
+  // //////////////////////////////////////////////
+  // //////////////////////////////////////////////
+
+  public static int lastFrameX = 200;
+
+  public static int lastFrameY = 200;
+
+  boolean fileFound = true;
+
+  String file = "No file";
+
+  Button launcher = new Button("Start Jalview");
+
+  /**
+   * The currentAlignFrame is static, it will change if and when the user
+   * selects a new window. Note that it will *never* point back to the embedded
+   * AlignFrame if the applet is started as embedded on the page and then
+   * afterwards a new view is created.
+   */
+  public AlignFrame currentAlignFrame = null;
+
+  /**
+   * This is the first frame to be displayed, and does not change. API calls
+   * will default to this instance if currentAlignFrame is null.
+   */
+  AlignFrame initialAlignFrame = null;
+
+  boolean embedded = false;
+
+  private boolean checkForJmol = true;
+
+  private boolean checkedForJmol = false; // ensure we don't check for jmol
+
+  // every time the app is re-inited
+
+  public boolean jmolAvailable = false;
+
+  private boolean alignPdbStructures = false;
+
+  /**
+   * use an external structure viewer exclusively (no jmols or MCViews will be
+   * opened by JalviewLite itself)
+   */
+  public boolean useXtrnalSviewer = false;
+
+  public static boolean debug = false;
+
+  static String builddate = null, version = null, installation = null;
+
+  private static void initBuildDetails()
+  {
+    if (builddate == null)
+    {
+      builddate = "unknown";
+      version = "test";
+      installation = "Webstart";
+      java.net.URL url = JalviewLite.class
+              .getResource("/.build_properties");
+      if (url != null)
+      {
+        try
+        {
+          BufferedReader reader = new BufferedReader(new InputStreamReader(
+                  url.openStream()));
+          String line;
+          while ((line = reader.readLine()) != null)
+          {
+            if (line.indexOf("VERSION") > -1)
+            {
+              version = line.substring(line.indexOf("=") + 1);
+            }
+            if (line.indexOf("BUILD_DATE") > -1)
+            {
+              builddate = line.substring(line.indexOf("=") + 1);
+            }
+            if (line.indexOf("INSTALLATION") > -1)
+            {
+              installation = line.substring(line.indexOf("=") + 1);
+            }
+          }
+        } catch (Exception ex)
+        {
+          ex.printStackTrace();
+        }
+      }
+    }
   }
-  public AlignFrame newView(String name)
+
+  public static String getBuildDate()
   {
-    return newView(currentAlignFrame, name);
+    initBuildDetails();
+    return builddate;
   }
 
-  public AlignFrame newView(AlignFrame alf)
+  public static String getInstallation()
   {
-    return alf.newView(null);
+    initBuildDetails();
+    return installation;
   }
-  public AlignFrame newView(AlignFrame alf, String name)
+
+  public static String getVersion()
   {
-    return alf.newView(name);
+    initBuildDetails();
+    return version;
   }
+
+  // public JSObject scriptObject = null;
+
   /**
-   * 
-   * @param text alignment file as a string
-   * @param title window title 
-   * @return null or new alignment frame
+   * init method for Jalview Applet
    */
-  public AlignFrame loadAlignment(String text, String title)
+  public void init()
   {
-    Alignment al = null;
-    String format = new IdentifyFile().Identify(text, AppletFormatAdapter.PASTE);
+    // remove any handlers that might be hanging around from an earlier instance
     try
     {
-      al = new AppletFormatAdapter().readFile(text,
-                                              AppletFormatAdapter.PASTE,
-                                              format);
-      if (al.getHeight() > 0)
+      if (debug)
       {
-        return new AlignFrame(al, this, title, false);
+        System.err.println("Applet context is '"
+                + getAppletContext().getClass().toString() + "'");
+      }
+      JSObject scriptObject = JSObject.getWindow(this);
+      if (debug && scriptObject != null)
+      {
+        System.err.println("Applet has Javascript callback support.");
+      }
+
+    } catch (Exception ex)
+    {
+      System.err
+              .println("Warning: No JalviewLite javascript callbacks available.");
+      if (debug)
+      {
+        ex.printStackTrace();
       }
     }
-    catch (java.io.IOException ex)
+    /**
+     * turn on extra applet debugging
+     */
+    String dbg = getParameter("debug");
+    if (dbg != null)
     {
-      ex.printStackTrace();
+      debug = dbg.toLowerCase().equals("true");
     }
-    return null;
-  }
-
-  ////////////////////////////////////////////////
-  ////////////////////////////////////////////////
-
-
-
-  static int lastFrameX = 200;
-  static int lastFrameY = 200;
-  boolean fileFound = true;
-  String file = "No file";
-  Button launcher = new Button("Start Jalview");
-
-  //The currentAlignFrame is static, it will change
-  //if and when the user selects a new window
-  public static AlignFrame currentAlignFrame;
-
-  //This is the first frame to be displayed, and does not change
-  AlignFrame initialAlignFrame;
-
-  boolean embedded = false;
+    if (debug)
+    {
 
-  public boolean jmolAvailable = false;
+      System.err.println("JalviewLite Version " + getVersion());
+      System.err.println("Build Date : " + getBuildDate());
+      System.err.println("Installation : " + getInstallation());
 
-  /**
-   * init method for Jalview Applet
-   */
-  public void init()
-  {
+    }
+    String externalsviewer = getParameter("externalstructureviewer");
+    if (externalsviewer != null)
+    {
+      useXtrnalSviewer = externalsviewer.trim().toLowerCase()
+              .equals("true");
+    }
+    /**
+     * if true disable the check for jmol
+     */
+    String chkforJmol = getParameter("nojmol");
+    if (chkforJmol != null)
+    {
+      checkForJmol = !chkforJmol.equals("true");
+    }
+    /**
+     * get the separator parameter if present
+     */
+    String sep = getParameter("separator");
+    if (sep != null)
+    {
+      if (sep.length() > 0)
+      {
+        separator = sep;
+        if (debug)
+        {
+          System.err.println("Separator set to '" + separator + "'");
+        }
+      }
+      else
+      {
+        throw new Error(MessageManager.getString("error.invalid_separator_parameter"));
+      }
+    }
     int r = 255;
     int g = 255;
     int b = 255;
@@ -216,31 +1419,29 @@ public class JalviewLite
         r = Integer.parseInt(param.substring(0, 2), 16);
         g = Integer.parseInt(param.substring(2, 4), 16);
         b = Integer.parseInt(param.substring(4, 6), 16);
-      }
-      catch (Exception ex)
+      } catch (Exception ex)
       {
         r = 255;
         g = 255;
         b = 255;
       }
     }
-
     param = getParameter("label");
     if (param != null)
     {
       launcher.setLabel(param);
     }
 
-    this.setBackground(new Color(r, g, b));
+    setBackground(new Color(r, g, b));
 
     file = getParameter("file");
 
     if (file == null)
     {
-      //Maybe the sequences are added as parameters
+      // Maybe the sequences are added as parameters
       StringBuffer data = new StringBuffer("PASTE");
       int i = 1;
-      while ( (file = getParameter("sequence" + i)) != null)
+      while ((file = getParameter("sequence" + i)) != null)
       {
         data.append(file.toString() + "\n");
         i++;
@@ -251,49 +1452,143 @@ public class JalviewLite
       }
     }
 
-    LoadJmolThread jmolAvailable = new LoadJmolThread();
-    jmolAvailable.start();
-
-    final JalviewLite applet = this;
+    final JalviewLite jvapplet = this;
     if (getParameter("embedded") != null
-        && getParameter("embedded").equalsIgnoreCase("true"))
+            && getParameter("embedded").equalsIgnoreCase("true"))
     {
+      // Launch as embedded applet in page
       embedded = true;
-      LoadingThread loader = new LoadingThread(file, applet);
+      LoadingThread loader = new LoadingThread(file, jvapplet);
       loader.start();
     }
     else if (file != null)
     {
-      add(launcher);
-
-      launcher.addActionListener(new java.awt.event.ActionListener()
+      if (getParameter("showbutton") == null
+              || !getParameter("showbutton").equalsIgnoreCase("false"))
       {
-        public void actionPerformed(ActionEvent e)
+        // Add the JalviewLite 'Button' to the page
+        add(launcher);
+        launcher.addActionListener(new java.awt.event.ActionListener()
         {
-          LoadingThread loader = new LoadingThread(file,
-              applet);
-          loader.start();
-        }
-      });
+          public void actionPerformed(ActionEvent e)
+          {
+            LoadingThread loader = new LoadingThread(file, jvapplet);
+            loader.start();
+          }
+        });
+      }
+      else
+      {
+        // Open jalviewLite immediately.
+        LoadingThread loader = new LoadingThread(file, jvapplet);
+        loader.start();
+      }
     }
     else
     {
+      // jalview initialisation with no alignment. loadAlignment() method can
+      // still be called to open new alignments.
       file = "NO FILE";
       fileFound = false;
+      callInitCallback();
+    }
+  }
+
+  private void initLiveConnect()
+  {
+    // try really hard to get the liveConnect thing working
+    boolean notFailed = false;
+    int tries = 0;
+    while (!notFailed && tries < 10)
+    {
+      if (tries > 0)
+      {
+        System.err.println("LiveConnect request thread going to sleep.");
+      }
+      try
+      {
+        Thread.sleep(700 * (1 + tries));
+      } catch (InterruptedException q)
+      {
+      }
+      ;
+      if (tries++ > 0)
+      {
+        System.err.println("LiveConnect request thread woken up.");
+      }
+      try
+      {
+        JSObject scriptObject = JSObject.getWindow(this);
+        if (scriptObject.eval("navigator") != null)
+        {
+          notFailed = true;
+        }
+      } catch (JSException jsex)
+      {
+        System.err.println("Attempt " + tries
+                + " to access LiveConnect javascript failed.");
+      }
     }
   }
 
+  private void callInitCallback()
+  {
+    String initjscallback = getParameter("oninit");
+    if (initjscallback == null)
+    {
+      return;
+    }
+    initjscallback = initjscallback.trim();
+    if (initjscallback.length() > 0)
+    {
+      JSObject scriptObject = null;
+      try
+      {
+        scriptObject = JSObject.getWindow(this);
+      } catch (Exception ex)
+      {
+      }
+      ;
+      // try really hard to let the browser plugin know we want liveconnect
+      initLiveConnect();
+
+      if (scriptObject != null)
+      {
+        try
+        {
+          // do onInit with the JS executor thread
+          new JSFunctionExec(this).executeJavascriptFunction(true,
+                  initjscallback, null, "Calling oninit callback '"
+                          + initjscallback + "'.");
+        } catch (Exception e)
+        {
+          System.err.println("Exception when executing _oninit callback '"
+                  + initjscallback + "'.");
+          e.printStackTrace();
+        }
+      }
+      else
+      {
+        System.err.println("Not executing _oninit callback '"
+                + initjscallback + "' - no scripting allowed.");
+      }
+    }
+  }
 
   /**
    * Initialises and displays a new java.awt.Frame
-   *
-   * @param frame java.awt.Frame to be displayed
-   * @param title title of new frame
-   * @param width width if new frame
-   * @param height height of new frame
+   * 
+   * @param frame
+   *          java.awt.Frame to be displayed
+   * @param title
+   *          title of new frame
+   * @param width
+   *          width if new frame
+   * @param height
+   *          height of new frame
    */
   public static void addFrame(final Frame frame, String title, int width,
-                              int height)
+          int height)
   {
     frame.setLocation(lastFrameX, lastFrameY);
     lastFrameX += 40;
@@ -306,14 +1601,22 @@ public class JalviewLite
       {
         if (frame instanceof AlignFrame)
         {
-          ( (AlignFrame) frame).closeMenuItem_actionPerformed();
-        }
-        if (currentAlignFrame == frame)
-        {
-          currentAlignFrame = null;
+          AlignViewport vp = ((AlignFrame) frame).viewport;
+          ((AlignFrame) frame).closeMenuItem_actionPerformed();
+          if (vp.applet.currentAlignFrame == frame)
+          {
+            vp.applet.currentAlignFrame = null;
+          }
+          vp.applet = null;
+          vp = null;
+
         }
         lastFrameX -= 40;
         lastFrameY -= 40;
+        if (frame instanceof EmbmenuFrame)
+        {
+          ((EmbmenuFrame) frame).destroyMenus();
+        }
         frame.setMenuBar(null);
         frame.dispose();
       }
@@ -322,21 +1625,38 @@ public class JalviewLite
       {
         if (frame instanceof AlignFrame)
         {
-          currentAlignFrame = (AlignFrame) frame;
-          System.err.println("Activated window "+frame);
+          ((AlignFrame) frame).viewport.applet.currentAlignFrame = (AlignFrame) frame;
+          if (debug)
+          {
+            System.err.println("Activated window " + frame);
+          }
         }
+        // be good.
+        super.windowActivated(e);
       }
-
+      /*
+       * Probably not necessary to do this - see TODO above. (non-Javadoc)
+       * 
+       * @see
+       * java.awt.event.WindowAdapter#windowDeactivated(java.awt.event.WindowEvent
+       * )
+       * 
+       * public void windowDeactivated(WindowEvent e) { if (currentAlignFrame ==
+       * frame) { currentAlignFrame = null; if (debug) {
+       * System.err.println("Deactivated window "+frame); } }
+       * super.windowDeactivated(e); }
+       */
     });
     frame.setVisible(true);
   }
 
   /**
-   * This paints the background surrounding the "Launch Jalview button"
+   * This paints the background surrounding the "Launch Jalview button" <br>
    * <br>
-   * <br>If file given in parameter not found, displays error message
-   *
-   * @param g graphics context
+   * If file given in parameter not found, displays error message
+   * 
+   * @param g
+   *          graphics context
    */
   public void paint(Graphics g)
   {
@@ -346,51 +1666,131 @@ public class JalviewLite
       g.setColor(Color.cyan);
       g.fillRect(0, 0, getSize().width, getSize().height);
       g.setColor(Color.red);
-      g.drawString("Jalview can't open file", 5, 15);
+      g.drawString(
+              MessageManager.getString("label.jalview_cannot_open_file"),
+              5, 15);
       g.drawString("\"" + file + "\"", 5, 30);
     }
     else if (embedded)
     {
       g.setColor(Color.black);
       g.setFont(new Font("Arial", Font.BOLD, 24));
-      g.drawString("Jalview Applet", 50, this.getSize().height / 2 - 30);
-      g.drawString("Loading Data...", 50, this.getSize().height / 2);
+      g.drawString(MessageManager.getString("label.jalview_applet"), 50,
+              getSize().height / 2 - 30);
+      g.drawString(MessageManager.getString("label.loading_data") + "...",
+              50, getSize().height / 2);
     }
   }
 
+  /**
+   * get all components associated with the applet of the given type
+   * 
+   * @param class1
+   * @return
+   */
+  public Vector getAppletWindow(Class class1)
+  {
+    Vector wnds = new Vector();
+    Component[] cmp = getComponents();
+    if (cmp != null)
+    {
+      for (int i = 0; i < cmp.length; i++)
+      {
+        if (class1.isAssignableFrom(cmp[i].getClass()))
+        {
+          wnds.addElement(cmp);
+        }
+      }
+    }
+    return wnds;
+  }
 
   class LoadJmolThread extends Thread
   {
+    private boolean running = false;
+
     public void run()
     {
-      try
+      if (running || checkedForJmol)
       {
-        if (!System.getProperty("java.version").startsWith("1.1"))
+        return;
+      }
+      running = true;
+      if (checkForJmol)
+      {
+        try
+        {
+          if (!System.getProperty("java.version").startsWith("1.1"))
+          {
+            Class.forName("org.jmol.adapter.smarter.SmarterJmolAdapter");
+            jmolAvailable = true;
+          }
+          if (!jmolAvailable)
+          {
+            System.out
+                    .println("Jmol not available - Using MCview for structures");
+          }
+        } catch (java.lang.ClassNotFoundException ex)
         {
-          Class.forName("org.jmol.adapter.smarter.SmarterJmolAdapter");
-          jmolAvailable = true;
         }
       }
-      catch (java.lang.ClassNotFoundException ex)
+      else
       {
-        System.out.println("Jmol not available - Using MCview for structures");
+        jmolAvailable = false;
+        if (debug)
+        {
+          System.err
+                  .println("Skipping Jmol check. Will use MCView (probably)");
+        }
       }
+      checkedForJmol = true;
+      running = false;
     }
-  }
 
+    public boolean notFinished()
+    {
+      return running || !checkedForJmol;
+    }
+  }
 
-  class LoadingThread
-      extends Thread
+  class LoadingThread extends Thread
   {
+    /**
+     * State variable: File source
+     */
     String file;
+
+    /**
+     * State variable: protocol for access to file source
+     */
     String protocol;
+
+    /**
+     * State variable: format of file source
+     */
     String format;
+
+    String _file;
+
     JalviewLite applet;
 
-    public LoadingThread(String _file,
-                         JalviewLite _applet)
+    private void dbgMsg(String msg)
+    {
+      if (applet.debug)
+      {
+        System.err.println(msg);
+      }
+    }
+
+    /**
+     * update the protocol state variable for accessing the datasource located
+     * by file.
+     * 
+     * @param file
+     * @return possibly updated datasource string
+     */
+    public String setProtocolState(String file)
     {
-      file = _file;
       if (file.startsWith("PASTE"))
       {
         file = file.substring(5);
@@ -405,42 +1805,94 @@ public class JalviewLite
         file = addProtocol(file);
         protocol = AppletFormatAdapter.URL;
       }
-      format = new jalview.io.IdentifyFile().Identify(file, protocol);
+      dbgMsg("Protocol identified as '" + protocol + "'");
+      return file;
+    }
+
+    public LoadingThread(String _file, JalviewLite _applet)
+    {
+      this._file = _file;
       applet = _applet;
     }
 
     public void run()
     {
+      LoadJmolThread jmolchecker = new LoadJmolThread();
+      jmolchecker.start();
+      while (jmolchecker.notFinished())
+      {
+        // wait around until the Jmol check is complete.
+        try
+        {
+          Thread.sleep(2);
+        } catch (Exception e)
+        {
+        }
+        ;
+      }
       startLoading();
+      // applet.callInitCallback();
     }
 
     private void startLoading()
     {
+      AlignFrame newAlignFrame;
+      dbgMsg("Loading thread started with:\n>>file\n" + _file + ">>endfile");
+      file = setProtocolState(_file);
+
+      format = new jalview.io.IdentifyFile().Identify(file, protocol);
+      dbgMsg("File identified as '" + format + "'");
+      dbgMsg("Loading started.");
       Alignment al = null;
       try
       {
-        al = new AppletFormatAdapter().readFile(file, protocol,
-                                                format);
-      }
-      catch (java.io.IOException ex)
+        al = new AppletFormatAdapter().readFile(file, protocol, format);
+      } catch (java.io.IOException ex)
       {
+        dbgMsg("File load exception.");
         ex.printStackTrace();
+        if (debug)
+        {
+          try
+          {
+            FileParse fp = new FileParse(file, protocol);
+            String ln = null;
+            dbgMsg(">>>Dumping contents of '" + file + "' " + "("
+                    + protocol + ")");
+            while ((ln = fp.nextLine()) != null)
+            {
+              dbgMsg(ln);
+            }
+            dbgMsg(">>>Dump finished.");
+          } catch (Exception e)
+          {
+            System.err
+                    .println("Exception when trying to dump the content of the file parameter.");
+            e.printStackTrace();
+          }
+        }
       }
-      if ( (al != null) && (al.getHeight() > 0))
+      if ((al != null) && (al.getHeight() > 0))
       {
-        currentAlignFrame = new AlignFrame(al,
-                                           applet,
-                                           file,
-                                           embedded);
+        dbgMsg("Successfully loaded file.");
+        newAlignFrame = new AlignFrame(al, applet, file, embedded);
+        if (initialAlignFrame == null)
+        {
+          initialAlignFrame = newAlignFrame;
+        }
+        // update the focus.
+        currentAlignFrame = newAlignFrame;
 
         if (protocol == jalview.io.AppletFormatAdapter.PASTE)
         {
-          currentAlignFrame.setTitle("Sequences from " + getDocumentBase());
+          newAlignFrame.setTitle(MessageManager.formatMessage(
+                  "label.sequences_from", new String[]
+                  { applet.getDocumentBase().toString() }));
         }
 
-        initialAlignFrame = currentAlignFrame;
-
-        currentAlignFrame.statusBar.setText("Successfully loaded file " + file);
+        newAlignFrame.statusBar.setText(MessageManager.formatMessage(
+                "label.successfully_loaded_file", new String[]
+                { file }));
 
         String treeFile = applet.getParameter("tree");
         if (treeFile == null)
@@ -452,112 +1904,175 @@ public class JalviewLite
         {
           try
           {
-            if (inArchive(treeFile))
-            {
-              protocol = AppletFormatAdapter.CLASSLOADER;
-            }
-            else
-            {
-              protocol = AppletFormatAdapter.URL;
-              treeFile = addProtocol(treeFile);
-            }
-
+            treeFile = setProtocolState(treeFile);
+            /*
+             * if (inArchive(treeFile)) { protocol =
+             * AppletFormatAdapter.CLASSLOADER; } else { protocol =
+             * AppletFormatAdapter.URL; treeFile = addProtocol(treeFile); }
+             */
             jalview.io.NewickFile fin = new jalview.io.NewickFile(treeFile,
-                protocol);
+                    protocol);
 
             fin.parse();
 
             if (fin.getTree() != null)
             {
-              currentAlignFrame.loadTree(fin, treeFile);
+              newAlignFrame.loadTree(fin, treeFile);
+              dbgMsg("Successfuly imported tree.");
             }
-          }
-          catch (Exception ex)
+            else
+            {
+              dbgMsg("Tree parameter did not resolve to a valid tree.");
+            }
+          } catch (Exception ex)
           {
             ex.printStackTrace();
           }
         }
 
-        String param = getParameter("features");
-        if (param != null)
+        /*
+         * Try to load T-Coffee score file
+         */
+        String sScoreFile = applet.getParameter("scoreFile");
+        if (sScoreFile != null && !"".equals(sScoreFile))
         {
-          if (!inArchive(param))
+          try
+          {
+            if (debug)
+            {
+              System.err
+                      .println("Attempting to load T-COFFEE score file from the scoreFile parameter");
+            }
+            if (!newAlignFrame.loadScoreFile(sScoreFile))
+            {
+              System.err
+                      .println("Failed to parse T-COFFEE parameter as a valid score file ('"
+                              + sScoreFile + "')");
+            }
+          } catch (Exception e)
           {
-            param = addProtocol(param);
+            System.err.printf("Cannot read score file: '%s'. Cause: %s \n",
+                    sScoreFile, e.getMessage());
           }
+        }
+
+        // ///////////////////////////
+        // modify display of features
+        // we do this before any features have been loaded, ensuring any hidden
+        // groups are hidden when features first displayed
+        //
+        // hide specific groups
+        //
+        String param = applet.getParameter("hidefeaturegroups");
+        if (param != null)
+        {
+          newAlignFrame.setFeatureGroupState(separatorListToArray(param),
+                  false);
+          // applet.setFeatureGroupStateOn(newAlignFrame, param, false);
+        }
+        // show specific groups
+        param = applet.getParameter("showfeaturegroups");
+        if (param != null)
+        {
+          newAlignFrame.setFeatureGroupState(separatorListToArray(param),
+                  true);
+          // applet.setFeatureGroupStateOn(newAlignFrame, param, true);
+        }
+        // and now load features
+        param = applet.getParameter("features");
+        if (param != null)
+        {
+          param = setProtocolState(param);
 
-          currentAlignFrame.parseFeaturesFile(param, protocol);
+          newAlignFrame.parseFeaturesFile(param, protocol);
         }
 
-        param = getParameter("showFeatureSettings");
+        param = applet.getParameter("showFeatureSettings");
         if (param != null && param.equalsIgnoreCase("true"))
         {
-          currentAlignFrame.viewport.showSequenceFeatures(true);
-          new FeatureSettings(currentAlignFrame.alignPanel);
+          newAlignFrame.viewport.showSequenceFeatures(true);
+          new FeatureSettings(newAlignFrame.alignPanel);
         }
 
-        param = getParameter("annotations");
+        param = applet.getParameter("annotations");
         if (param != null)
         {
-          if (!inArchive(param))
+          param = setProtocolState(param);
+
+          if (new AnnotationFile().readAnnotationFile(
+                  newAlignFrame.viewport.getAlignment(), param, protocol))
           {
-            param = addProtocol(param);
+            newAlignFrame.alignPanel.fontChanged();
+            newAlignFrame.alignPanel.setScrollValues(0, 0);
+          }
+          else
+          {
+            System.err
+                    .println("Annotations were not added from annotation file '"
+                            + param + "'");
           }
-
-          new AnnotationFile().readAnnotationFile(
-              currentAlignFrame.viewport.getAlignment(),
-              param,
-              protocol);
-
-          currentAlignFrame.alignPanel.fontChanged();
-          currentAlignFrame.alignPanel.setScrollValues(0, 0);
 
         }
 
-        param = getParameter("jnetfile");
+        param = applet.getParameter("jnetfile");
         if (param != null)
         {
           try
           {
-            if (inArchive(param))
-            {
-              protocol = AppletFormatAdapter.CLASSLOADER;
-            }
-            else
-            {
-              protocol = AppletFormatAdapter.URL;
-              param = addProtocol(param);
-            }
-
+            param = setProtocolState(param);
             jalview.io.JPredFile predictions = new jalview.io.JPredFile(
-                param, protocol);
-            new JnetAnnotationMaker().add_annotation(predictions,
-                currentAlignFrame.viewport.getAlignment(),
-                0, false); // do not add sequence profile from concise output
-            currentAlignFrame.alignPanel.fontChanged();
-            currentAlignFrame.alignPanel.setScrollValues(0, 0);
-          }
-          catch (Exception ex)
+                    param, protocol);
+            JnetAnnotationMaker.add_annotation(predictions,
+                    newAlignFrame.viewport.getAlignment(), 0, false); // false==do
+            // not
+            // add
+            // sequence
+            // profile
+            // from
+            // concise
+            // output
+            newAlignFrame.alignPanel.fontChanged();
+            newAlignFrame.alignPanel.setScrollValues(0, 0);
+          } catch (Exception ex)
           {
             ex.printStackTrace();
           }
         }
-
         /*
-         <param name="PDBfile" value="1gaq.txt PDB|1GAQ|1GAQ|A PDB|1GAQ|1GAQ|B PDB|1GAQ|1GAQ|C">
-
-         <param name="PDBfile2" value="1gaq.txt A=SEQA B=SEQB C=SEQB">
-
-         <param name="PDBfile3" value="1q0o Q45135_9MICO">
-        */
-
+         * <param name="alignpdbfiles" value="false/true"/> Undocumented for 2.6
+         * - related to JAL-434
+         */
+        applet.setAlignPdbStructures(getDefaultParameter("alignpdbfiles",
+                false));
+        /*
+         * <param name="PDBfile" value="1gaq.txt PDB|1GAQ|1GAQ|A PDB|1GAQ|1GAQ|B
+         * PDB|1GAQ|1GAQ|C">
+         * 
+         * <param name="PDBfile2" value="1gaq.txt A=SEQA B=SEQB C=SEQB">
+         * 
+         * <param name="PDBfile3" value="1q0o Q45135_9MICO">
+         */
 
         int pdbFileCount = 0;
-        do{
+        // Accumulate pdbs here if they are heading for the same view (if
+        // alignPdbStructures is true)
+        Vector pdbs = new Vector();
+        // create a lazy matcher if we're asked to
+        jalview.analysis.SequenceIdMatcher matcher = (applet
+                .getDefaultParameter("relaxedidmatch", false)) ? new jalview.analysis.SequenceIdMatcher(
+                newAlignFrame.getAlignViewport().getAlignment()
+                        .getSequencesArray()) : null;
+
+        do
+        {
           if (pdbFileCount > 0)
-            param = getParameter("PDBFILE" + pdbFileCount);
+          {
+            param = applet.getParameter("PDBFILE" + pdbFileCount);
+          }
           else
-            param = getParameter("PDBFILE");
+          {
+            param = applet.getParameter("PDBFILE");
+          }
 
           if (param != null)
           {
@@ -565,7 +2080,7 @@ public class JalviewLite
 
             String seqstring;
             SequenceI[] seqs = null;
-            String [] chains = null;
+            String[] chains = null;
 
             StringTokenizer st = new StringTokenizer(param, " ");
 
@@ -573,11 +2088,12 @@ public class JalviewLite
             {
               String sequence = applet.getParameter("PDBSEQ");
               if (sequence != null)
+              {
                 seqs = new SequenceI[]
-                    {
-                    (Sequence) currentAlignFrame.
-                    getAlignViewport().getAlignment().
-                    findName(sequence)};
+                { matcher == null ? (Sequence) newAlignFrame
+                        .getAlignViewport().getAlignment()
+                        .findName(sequence) : matcher.findIdMatch(sequence) };
+              }
 
             }
             else
@@ -589,94 +2105,137 @@ public class JalviewLite
               while (st.hasMoreTokens())
               {
                 seqstring = st.nextToken();
-                StringTokenizer st2 = new StringTokenizer(seqstring,"=");
-                if(st2.countTokens()>1)
+                StringTokenizer st2 = new StringTokenizer(seqstring, "=");
+                if (st2.countTokens() > 1)
                 {
-                  //This is the chain
+                  // This is the chain
                   tmp2.addElement(st2.nextToken());
                   seqstring = st2.nextToken();
                 }
-                tmp.addElement( (Sequence) currentAlignFrame.
-                                 getAlignViewport().getAlignment().
-                                 findName(seqstring));
+                tmp.addElement(matcher == null ? (Sequence) newAlignFrame
+                        .getAlignViewport().getAlignment()
+                        .findName(seqstring) : matcher
+                        .findIdMatch(seqstring));
               }
 
               seqs = new SequenceI[tmp.size()];
               tmp.copyInto(seqs);
-              if(tmp2.size()==tmp.size())
+              if (tmp2.size() == tmp.size())
               {
                 chains = new String[tmp2.size()];
                 tmp2.copyInto(chains);
               }
             }
+            param = setProtocolState(param);
 
-            if (inArchive(param) && !jmolAvailable)
+            if (// !jmolAvailable
+            // &&
+            protocol == AppletFormatAdapter.CLASSLOADER
+                    && !useXtrnalSviewer)
             {
-              protocol = AppletFormatAdapter.CLASSLOADER;
-            }
-            else
-            {
-              protocol = AppletFormatAdapter.URL;
-              param = addProtocol(param);
+              // Re: JAL-357 : the bug isn't a problem if we are using an
+              // external viewer!
+              // TODO: verify this Re:
+              // https://mantis.lifesci.dundee.ac.uk/view.php?id=36605
+              // This exception preserves the current behaviour where, even if
+              // the local pdb file was identified in the class loader
+              protocol = AppletFormatAdapter.URL; // this is probably NOT
+              // CORRECT!
+              param = addProtocol(param); //
             }
 
             pdb.setFile(param);
 
-            if(seqs!=null)
+            if (seqs != null)
             {
               for (int i = 0; i < seqs.length; i++)
               {
-                ( (Sequence) seqs[i]).addPDBId(pdb);
+                if (seqs[i] != null)
+                {
+                  ((Sequence) seqs[i]).addPDBId(pdb);
+                  StructureSelectionManager.getStructureSelectionManager(
+                          applet).registerPDBEntry(pdb);
+                }
+                else
+                {
+                  if (JalviewLite.debug)
+                  {
+                    // this may not really be a problem but we give a warning
+                    // anyway
+                    System.err
+                            .println("Warning: Possible input parsing error: Null sequence for attachment of PDB (sequence "
+                                    + i + ")");
+                  }
+                }
               }
 
-              if (jmolAvailable)
+              if (!alignPdbStructures)
               {
-                new jalview.appletgui.AppletJmol(pdb,
-                                                 seqs,
-                                                 chains,
-                                                 currentAlignFrame.alignPanel,
-                                                 protocol);
-                lastFrameX += 40;
-                lastFrameY+=40;
+                newAlignFrame.newStructureView(applet, pdb, seqs, chains,
+                        protocol);
               }
               else
-                    new MCview.AppletPDBViewer(pdb,
-                                           seqs,
-                                           chains,
-                                           currentAlignFrame.alignPanel,
-                                           protocol);
+              {
+                pdbs.addElement(new Object[]
+                { pdb, seqs, chains, new String(protocol) });
+              }
             }
           }
 
           pdbFileCount++;
-        }
-        while(pdbFileCount < 10);
+        } while (param != null || pdbFileCount < 10);
+        if (pdbs.size() > 0)
+        {
+          SequenceI[][] seqs = new SequenceI[pdbs.size()][];
+          PDBEntry[] pdb = new PDBEntry[pdbs.size()];
+          String[][] chains = new String[pdbs.size()][];
+          String[] protocols = new String[pdbs.size()];
+          for (int pdbsi = 0, pdbsiSize = pdbs.size(); pdbsi < pdbsiSize; pdbsi++)
+          {
+            Object[] o = (Object[]) pdbs.elementAt(pdbsi);
+            pdb[pdbsi] = (PDBEntry) o[0];
+            seqs[pdbsi] = (SequenceI[]) o[1];
+            chains[pdbsi] = (String[]) o[2];
+            protocols[pdbsi] = (String) o[3];
+          }
+          newAlignFrame.alignedStructureView(applet, pdb, seqs, chains,
+                  protocols);
 
+        }
       }
       else
       {
         fileFound = false;
-        remove(launcher);
-        repaint();
+        applet.remove(launcher);
+        applet.repaint();
       }
+      callInitCallback();
     }
 
     /**
      * Discovers whether the given file is in the Applet Archive
-     * @param file String
+     * 
+     * @param file
+     *          String
      * @return boolean
      */
     boolean inArchive(String file)
     {
-      //This might throw a security exception in certain browsers
-      //Netscape Communicator for instance.
+      // This might throw a security exception in certain browsers
+      // Netscape Communicator for instance.
       try
       {
-        return (getClass().getResourceAsStream("/" + file) != null);
-      }
-      catch (Exception ex)
+        boolean rtn = (getClass().getResourceAsStream("/" + file) != null);
+        if (debug)
+        {
+          System.err.println("Resource '" + file + "' was "
+                  + (rtn ? "" : "not") + " located by classloader.");
+        }
+        return rtn;
+      } catch (Exception ex)
       {
-        System.out.println("Exception checking resources: " + file + " " + ex);
+        System.out.println("Exception checking resources: " + file + " "
+                + ex);
         return false;
       }
     }
@@ -685,92 +2244,573 @@ public class JalviewLite
     {
       if (file.indexOf("://") == -1)
       {
-        file = getCodeBase() + file;
+        String fl = applet.resolveUrlForLocalOrAbsolute(file,
+                getDocumentBase());
+        try
+        {
+          if (new java.net.URL(fl).openStream() != null)
+          {
+            if (debug)
+            {
+              System.err.println("Prepended document base for resource: '"
+                      + file + "'");
+            }
+            return fl;
+          }
+        } catch (Exception x)
+        {
+        }
+        ;
+        fl = applet.resolveUrlForLocalOrAbsolute(file, getCodeBase());
+        try
+        {
+          if (new java.net.URL(fl).openStream() != null)
+          {
+            if (debug)
+            {
+              System.err.println("Prepended codebase for resource: '"
+                      + file + "'");
+            }
+            return fl;
+          }
+        } catch (Exception x)
+        {
+        }
+        ;
+
       }
 
       return file;
     }
   }
 
-  public String[] tabbedListToArray(String list)
+  /**
+   * @return the default alignFrame acted on by the public applet methods. May
+   *         return null with an error message on System.err indicating the
+   *         fact.
+   */
+  public AlignFrame getDefaultTargetFrame()
+  {
+    if (currentAlignFrame != null)
+    {
+      return currentAlignFrame;
+    }
+    if (initialAlignFrame != null)
+    {
+      return initialAlignFrame;
+    }
+    System.err
+            .println("Implementation error: Jalview Applet API cannot work out which AlignFrame to use.");
+    return null;
+  }
+
+  /**
+   * separator used for separatorList
+   */
+  protected String separator = "" + ((char) 0x00AC); // the default used to be
+                                                     // '|' but many sequence
+                                                     // IDS include pipes.
+
+  /**
+   * set to enable the URL based javascript execution mechanism
+   */
+  public boolean jsfallbackEnabled = false;
+
+  /**
+   * parse the string into a list
+   * 
+   * @param list
+   * @return elements separated by separator
+   */
+  public String[] separatorListToArray(String list)
+  {
+    return separatorListToArray(list, separator);
+  }
+
+  /**
+   * parse the string into a list
+   * 
+   * @param list
+   * @param separator
+   * @return elements separated by separator
+   */
+  public String[] separatorListToArray(String list, String separator)
   {
-    if (list==null || list.equals(""))
+    // note separator local variable intentionally masks object field
+    int seplen = separator.length();
+    if (list == null || list.equals("") || list.equals(separator))
+    {
       return null;
+    }
     java.util.Vector jv = new Vector();
-    int cp=0,pos;
-    while ((pos=list.indexOf("\t",cp))>cp)
+    int cp = 0, pos;
+    while ((pos = list.indexOf(separator, cp)) > cp)
     {
-      jv.addElement(list.substring(cp,pos));
-      cp = pos+1;
+      jv.addElement(list.substring(cp, pos));
+      cp = pos + seplen;
     }
-    if (cp<list.length())
+    if (cp < list.length())
     {
-      jv.addElement(list.substring(cp));
+      String c = list.substring(cp);
+      if (!c.equals(separator))
+      {
+        jv.addElement(c);
+      }
     }
-    if (jv.size()>0)
-    { String[] v = new String[jv.size()];
-      jv.copyInto(v);
+    if (jv.size() > 0)
+    {
+      String[] v = new String[jv.size()];
+      for (int i = 0; i < v.length; i++)
+      {
+        v[i] = (String) jv.elementAt(i);
+      }
       jv.removeAllElements();
-      System.err.println("Array from Tabbed List:\n"+v.length+"\n"+v.toString());
+      if (debug)
+      {
+        System.err.println("Array from '" + separator
+                + "' separated List:\n" + v.length);
+        for (int i = 0; i < v.length; i++)
+        {
+          System.err.println("item " + i + " '" + v[i] + "'");
+        }
+      }
       return v;
     }
-    System.err.println("Empty Array from Tabbed List");
+    if (debug)
+    {
+      System.err.println("Empty Array from '" + separator
+              + "' separated List");
+    }
     return null;
   }
 
-  public String ArraytotabbedList(String[] list)
+  /**
+   * concatenate the list with separator
+   * 
+   * @param list
+   * @return concatenated string
+   */
+  public String arrayToSeparatorList(String[] list)
+  {
+    return arrayToSeparatorList(list, separator);
+  }
+
+  /**
+   * concatenate the list with separator
+   * 
+   * @param list
+   * @param separator
+   * @return concatenated string
+   */
+  public String arrayToSeparatorList(String[] list, String separator)
   {
     StringBuffer v = new StringBuffer();
-    if (list!=null)
+    if (list != null && list.length > 0)
     {
-      for (int i=0,iSize=list.length-1;i<iSize;i++)
-      { 
-        if (list[i]!=null)
-        {  
-          v.append(list[i]); 
+      for (int i = 0, iSize = list.length; i < iSize; i++)
+      {
+        if (list[i] != null)
+        {
+          if (i > 0)
+          {
+            v.append(separator);
+          }
+          v.append(list[i]);
         }
-        v.append("\t");
       }
-      if (list[list.length-1]!=null)
-      { v.append(list[list.length-1]);
+      if (debug)
+      {
+        System.err.println("Returning '" + separator
+                + "' separated List:\n");
+        System.err.println(v);
       }
-      System.err.println("Tabbed List:\n"+v.toString());
       return v.toString();
     }
-    System.err.println("Empty Tabbed List\n");
-    return "";
+    if (debug)
+    {
+      System.err.println("Returning empty '" + separator
+              + "' separated List\n");
+    }
+    return "" + separator;
   }
-  /**
-   * @return
-   * @see jalview.appletgui.AlignFrame#getFeatureGroups()
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getFeatureGroups()
    */
   public String getFeatureGroups()
   {
-    String lst = ArraytotabbedList(currentAlignFrame.getFeatureGroups());
+    String lst = arrayToSeparatorList(getDefaultTargetFrame()
+            .getFeatureGroups());
+    return lst;
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getFeatureGroupsOn(jalview.appletgui.AlignFrame
+   * )
+   */
+  public String getFeatureGroupsOn(AlignFrame alf)
+  {
+    String lst = arrayToSeparatorList(alf.getFeatureGroups());
     return lst;
   }
 
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getFeatureGroupsOfState(boolean)
+   */
+  public String getFeatureGroupsOfState(boolean visible)
+  {
+    return arrayToSeparatorList(getDefaultTargetFrame()
+            .getFeatureGroupsOfState(visible));
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see
+   * jalview.bin.JalviewLiteJsApi#getFeatureGroupsOfStateOn(jalview.appletgui
+   * .AlignFrame, boolean)
+   */
+  public String getFeatureGroupsOfStateOn(AlignFrame alf, boolean visible)
+  {
+    return arrayToSeparatorList(alf.getFeatureGroupsOfState(visible));
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#setFeatureGroupStateOn(jalview.appletgui.
+   * AlignFrame, java.lang.String, boolean)
+   */
+  public void setFeatureGroupStateOn(final AlignFrame alf,
+          final String groups, boolean state)
+  {
+    final boolean st = state;// !(state==null || state.equals("") ||
+    // state.toLowerCase().equals("false"));
+    java.awt.EventQueue.invokeLater(new Runnable()
+    {
+      @Override
+      public void run()
+      {
+        alf.setFeatureGroupState(separatorListToArray(groups), st);
+      }
+    });
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#setFeatureGroupState(java.lang.String,
+   * boolean)
+   */
+  public void setFeatureGroupState(String groups, boolean state)
+  {
+    setFeatureGroupStateOn(getDefaultTargetFrame(), groups, state);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getSeparator()
+   */
+  public String getSeparator()
+  {
+    return separator;
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#setSeparator(java.lang.String)
+   */
+  public void setSeparator(String separator)
+  {
+    if (separator == null || separator.length() < 1)
+    {
+      // reset to default
+      separator = "" + ((char) 0x00AC);
+    }
+    this.separator = separator;
+    if (debug)
+    {
+      System.err.println("Default Separator now: '" + separator + "'");
+    }
+  }
+
+  /**
+   * get boolean value of applet parameter 'name' and return default if
+   * parameter is not set
+   * 
+   * @param name
+   *          name of paremeter
+   * @param def
+   *          the value to return otherwise
+   * @return true or false
+   */
+  public boolean getDefaultParameter(String name, boolean def)
+  {
+    String stn;
+    if ((stn = getParameter(name)) == null)
+    {
+      return def;
+    }
+    if (stn.toLowerCase().equals("true"))
+    {
+      return true;
+    }
+    return false;
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#addPdbFile(jalview.appletgui.AlignFrame,
+   * java.lang.String, java.lang.String, java.lang.String)
+   */
+  public boolean addPdbFile(AlignFrame alFrame, String sequenceId,
+          String pdbEntryString, String pdbFile)
+  {
+    return alFrame.addPdbFile(sequenceId, pdbEntryString, pdbFile);
+  }
+
+  protected void setAlignPdbStructures(boolean alignPdbStructures)
+  {
+    this.alignPdbStructures = alignPdbStructures;
+  }
+
+  public boolean isAlignPdbStructures()
+  {
+    return alignPdbStructures;
+  }
+
+  public void start()
+  {
+    // callInitCallback();
+  }
+
+  private Hashtable<String, long[]> jshashes = new Hashtable<String, long[]>();
+
+  private Hashtable<String, Hashtable<String, String[]>> jsmessages = new Hashtable<String, Hashtable<String, String[]>>();
+
+  public void setJsMessageSet(String messageclass, String viewId,
+          String[] colcommands)
+  {
+    Hashtable<String, String[]> msgset = jsmessages.get(messageclass);
+    if (msgset == null)
+    {
+      msgset = new Hashtable<String, String[]>();
+      jsmessages.put(messageclass, msgset);
+    }
+    msgset.put(viewId, colcommands);
+    long[] l = new long[colcommands.length];
+    for (int i = 0; i < colcommands.length; i++)
+    {
+      l[i] = colcommands[i].hashCode();
+    }
+    jshashes.put(messageclass + "|" + viewId, l);
+  }
+
+  /*
+   * (non-Javadoc)
+   * 
+   * @see jalview.bin.JalviewLiteJsApi#getJsMessage(java.lang.String,
+   * java.lang.String)
+   */
+  public String getJsMessage(String messageclass, String viewId)
+  {
+    Hashtable<String, String[]> msgset = jsmessages.get(messageclass);
+    if (msgset != null)
+    {
+      String[] msgs = msgset.get(viewId);
+      if (msgs != null)
+      {
+        for (int i = 0; i < msgs.length; i++)
+        {
+          if (msgs[i] != null)
+          {
+            String m = msgs[i];
+            msgs[i] = null;
+            return m;
+          }
+        }
+      }
+    }
+    return "";
+  }
+
+  public boolean isJsMessageSetChanged(String string, String string2,
+          String[] colcommands)
+  {
+    long[] l = jshashes.get(string + "|" + string2);
+    if (l == null && colcommands != null)
+    {
+      return true;
+    }
+    for (int i = 0; i < colcommands.length; i++)
+    {
+      if (l[i] != colcommands[i].hashCode())
+      {
+        return true;
+      }
+    }
+    return false;
+  }
+
+  private Vector jsExecQueue = new Vector();
+
+  public Vector getJsExecQueue()
+  {
+    return jsExecQueue;
+  }
+
+  public void setExecutor(JSFunctionExec jsFunctionExec2)
+  {
+    jsFunctionExec = jsFunctionExec2;
+  }
+
   /**
-   * @param visible
+   * return the given colour value parameter or the given default if parameter
+   * not given
+   * 
+   * @param colparam
+   * @param defcolour
    * @return
-   * @see jalview.appletgui.AlignFrame#getFeatureGroupsOfState(boolean)
    */
-  public String getFeatureGroupsOfState(boolean visible)
+  public Color getDefaultColourParameter(String colparam, Color defcolour)
+  {
+    String colprop = getParameter(colparam);
+    if (colprop == null || colprop.trim().length() == 0)
+    {
+      return defcolour;
+    }
+    Color col = jalview.schemes.ColourSchemeProperty
+            .getAWTColorFromName(colprop);
+    if (col == null)
+    {
+      try
+      {
+        col = new jalview.schemes.UserColourScheme(colprop).findColour('A');
+      } catch (Exception ex)
+      {
+        System.err.println("Couldn't parse '" + colprop
+                + "' as a colour for " + colparam);
+        col = null;
+      }
+    }
+    return (col == null) ? defcolour : col;
+
+  }
+
+  public void openJalviewHelpUrl()
   {
-    return ArraytotabbedList(currentAlignFrame.getFeatureGroupsOfState(visible));
+    String helpUrl = getParameter("jalviewhelpurl");
+    if (helpUrl == null || helpUrl.trim().length() < 5)
+    {
+      helpUrl = "http://www.jalview.org/help.html";
+    }
+    showURL(helpUrl, "HELP");
   }
+
   /**
-   * @param groups tab separated list of group names 
-   * @param state true or false
-   * @see jalview.appletgui.AlignFrame#setFeatureGroupState(java.lang.String[], boolean)
+   * form a complete URL given a path to a resource and a reference location on
+   * the same server
+   * 
+   * @param url
+   *          - an absolute path on the same server as localref or a document
+   *          located relative to localref
+   * @param localref
+   *          - a URL on the same server as url
+   * @return a complete URL for the resource located by url
    */
-  public void setFeatureGroupState(AlignFrame alf, String groups, boolean state)
+  private String resolveUrlForLocalOrAbsolute(String url, URL localref)
   {
-    boolean st = state;//!(state==null || state.equals("") || state.toLowerCase().equals("false"));
-    alf.setFeatureGroupState(tabbedListToArray(groups), st);
+    String codebase = localref.toString();
+    if (url.indexOf("/") == 0)
+    {
+      url = codebase.substring(0, codebase.length()
+              - localref.getFile().length())
+              + url;
+    }
+    else
+    {
+      url = localref + url;
+    }
+    return url;
   }
-  public void setFeatureGroupState(String groups, boolean state)
+
+  /**
+   * open a URL in the browser - resolving it according to relative refs and
+   * coping with javascript: protocol if necessary.
+   * 
+   * @param url
+   * @param target
+   */
+  public void showURL(String url, String target)
   {
-    setFeatureGroupState(currentAlignFrame, groups, state);
+    try
+    {
+      if (url.indexOf(":") == -1)
+      {
+        // TODO: verify (Bas Vroling bug) prepend codebase or server URL to
+        // form valid URL
+        // Should really use docbase, not codebase.
+        URL prepend;
+        url = resolveUrlForLocalOrAbsolute(
+                url,
+                prepend = getDefaultParameter("resolvetocodebase", false) ? getDocumentBase()
+                        : getCodeBase());
+        if (debug)
+        {
+          System.err
+                  .println("Show url (prepended "
+                          + prepend
+                          + " - toggle resolvetocodebase if code/docbase resolution is wrong): "
+                          + url);
+        }
+      }
+      else
+      {
+        if (debug)
+        {
+          System.err.println("Show url: " + url);
+        }
+      }
+      if (url.indexOf("javascript:") == 0)
+      {
+        // no target for the javascript context
+        getAppletContext().showDocument(new java.net.URL(url));
+      }
+      else
+      {
+        getAppletContext().showDocument(new java.net.URL(url), target);
+      }
+    } catch (Exception ex)
+    {
+      ex.printStackTrace();
+    }
   }
+
+  /**
+   * bind structures in a viewer to any matching sequences in an alignFrame (use
+   * sequenceIds to limit scope of search to specific sequences)
+   * 
+   * @param alFrame
+   * @param viewer
+   * @param sequenceIds
+   * @return TODO: consider making an exception structure for indicating when
+   *         binding fails public SequenceStructureBinding
+   *         addStructureViewInstance( AlignFrame alFrame, Object viewer, String
+   *         sequenceIds) {
+   * 
+   *         if (sequenceIds != null && sequenceIds.length() > 0) { return
+   *         alFrame.addStructureViewInstance(viewer,
+   *         separatorListToArray(sequenceIds)); } else { return
+   *         alFrame.addStructureViewInstance(viewer, null); } // return null; }
+   */
 }