JAL-1645 Version-Rel Version 2.9 Year-Rel 2015 Licensing glob
[jalview.git] / src / jalview / gui / PopupMenu.java
index 3ea689f..d344c0c 100644 (file)
@@ -1,6 +1,6 @@
 /*
- * Jalview - A Sequence Alignment Editor and Viewer (Version 2.8.2)
- * Copyright (C) 2014 The Jalview Authors
+ * Jalview - A Sequence Alignment Editor and Viewer (Version 2.9)
+ * Copyright (C) 2015 The Jalview Authors
  * 
  * This file is part of Jalview.
  * 
@@ -22,6 +22,7 @@ package jalview.gui;
 
 import jalview.analysis.AAFrequency;
 import jalview.analysis.AlignmentAnnotationUtils;
+import jalview.analysis.AlignmentUtils;
 import jalview.analysis.Conservation;
 import jalview.commands.ChangeCaseCommand;
 import jalview.commands.EditCommand;
@@ -29,6 +30,7 @@ import jalview.commands.EditCommand.Action;
 import jalview.datamodel.AlignmentAnnotation;
 import jalview.datamodel.AlignmentI;
 import jalview.datamodel.Annotation;
+import jalview.datamodel.ColumnSelection;
 import jalview.datamodel.DBRefEntry;
 import jalview.datamodel.PDBEntry;
 import jalview.datamodel.Sequence;
@@ -60,9 +62,7 @@ import jalview.util.UrlLink;
 import java.awt.Color;
 import java.awt.event.ActionEvent;
 import java.awt.event.ActionListener;
-import java.util.ArrayList;
 import java.util.Arrays;
-import java.util.Collection;
 import java.util.Collections;
 import java.util.Hashtable;
 import java.util.LinkedHashMap;
@@ -124,9 +124,6 @@ public class PopupMenu extends JPopupMenu
 
   protected JRadioButtonMenuItem RNAInteractionColour = new JRadioButtonMenuItem();
 
-  // protected JRadioButtonMenuItem covariationColour = new
-  // JRadioButtonMenuItem();
-
   JRadioButtonMenuItem noColourmenuItem = new JRadioButtonMenuItem();
 
   protected JCheckBoxMenuItem conservationMenuItem = new JCheckBoxMenuItem();
@@ -141,6 +138,8 @@ public class PopupMenu extends JPopupMenu
 
   JMenuItem sequenceSelDetails = new JMenuItem();
 
+  JMenuItem makeReferenceSeq = new JMenuItem();
+
   JMenuItem chooseAnnotations = new JMenuItem();
 
   SequenceI sequence;
@@ -179,12 +178,6 @@ public class PopupMenu extends JPopupMenu
 
   JMenuItem pdbFromFile = new JMenuItem();
 
-  // JBPNote: Commented these out - Should add these services via the web
-  // services menu system.
-  // JMenuItem ContraFold = new JMenuItem();
-
-  // JMenuItem RNAFold = new JMenuItem();
-
   JMenuItem enterPDB = new JMenuItem();
 
   JMenuItem discoverPDB = new JMenuItem();
@@ -195,13 +188,15 @@ public class PopupMenu extends JPopupMenu
 
   JMenu seqHideAnnotationsMenu = new JMenu();
 
-  JMenuItem seqAddReferenceAnnotations = new JMenuItem();
+  JMenuItem seqAddReferenceAnnotations = new JMenuItem(
+          MessageManager.getString("label.add_reference_annotations"));
 
   JMenu groupShowAnnotationsMenu = new JMenu();
 
   JMenu groupHideAnnotationsMenu = new JMenu();
 
-  JMenuItem groupAddReferenceAnnotations = new JMenuItem();
+  JMenuItem groupAddReferenceAnnotations = new JMenuItem(
+          MessageManager.getString("label.add_reference_annotations"));
 
   JMenuItem sequenceFeature = new JMenuItem();
 
@@ -209,17 +204,16 @@ public class PopupMenu extends JPopupMenu
 
   JMenu jMenu1 = new JMenu();
 
-  JMenu structureMenu = new JMenu();
+  JMenuItem pdbStructureDialog = new JMenuItem();
 
-  JMenu viewStructureMenu = new JMenu();
+  JMenu rnaStructureMenu = new JMenu();
 
-  // JMenu colStructureMenu = new JMenu();
   JMenuItem editSequence = new JMenuItem();
 
-  // JMenuItem annotationMenuItem = new JMenuItem();
-
   JMenu groupLinksMenu;
 
+  JMenuItem hideInsertions = new JMenuItem();
+
   /**
    * Creates a new PopupMenu object.
    * 
@@ -268,7 +262,6 @@ public class PopupMenu extends JPopupMenu
     colours.add(BLOSUM62Colour);
     colours.add(purinePyrimidineColour);
     colours.add(RNAInteractionColour);
-    // colours.add(covariationColour);
 
     for (int i = 0; i < jalview.io.FormatAdapter.WRITEABLE_FORMATS.length; i++)
     {
@@ -322,126 +315,88 @@ public class PopupMenu extends JPopupMenu
     if (seq != null)
     {
       sequenceMenu.setText(sequence.getName());
-
-      if (seq.getDatasetSequence().getPDBId() != null
-              && seq.getDatasetSequence().getPDBId().size() > 0)
+      if (seq == ap.av.getAlignment().getSeqrep())
       {
-        java.util.Enumeration e = seq.getDatasetSequence().getPDBId()
-                .elements();
-
-        while (e.hasMoreElements())
-        {
-          final PDBEntry pdb = (PDBEntry) e.nextElement();
-
-          menuItem = new JMenuItem();
-          menuItem.setText(pdb.getId());
-          menuItem.addActionListener(new ActionListener()
-          {
-            @Override
-            public void actionPerformed(ActionEvent e)
-            {
-              // TODO re JAL-860: optionally open dialog or provide a menu entry
-              // allowing user to open just one structure per sequence
-              // new AppJmol(pdb, ap.av.collateForPDB(new PDBEntry[]
-              // { pdb })[0], null, ap);
-              new StructureViewer(ap.getStructureSelectionManager())
-                      .viewStructures(pdb,
-                              ap.av.collateForPDB(new PDBEntry[]
-                              { pdb })[0], null, ap);
-            }
-          });
-          viewStructureMenu.add(menuItem);
-
-          /*
-           * menuItem = new JMenuItem(); menuItem.setText(pdb.getId());
-           * menuItem.addActionListener(new java.awt.event.ActionListener() {
-           * public void actionPerformed(ActionEvent e) {
-           * colourByStructure(pdb.getId()); } });
-           * colStructureMenu.add(menuItem);
-           */
-        }
+        makeReferenceSeq.setText(MessageManager
+                .getString("action.unmark_as_reference"));
       }
       else
       {
-        if (ap.av.getAlignment().isNucleotide() == false)
-        {
-          structureMenu.remove(viewStructureMenu);
-        }
-        // structureMenu.remove(colStructureMenu);
+        makeReferenceSeq.setText(MessageManager
+                .getString("action.set_as_reference"));
       }
 
-      if (ap.av.getAlignment().isNucleotide() == true)
+      if (!ap.av.getAlignment().isNucleotide())
+      {
+        remove(rnaStructureMenu);
+      }
+      else
       {
-        AlignmentAnnotation[] aa = ap.av.getAlignment()
+        int origCount = rnaStructureMenu.getItemCount();
+        /*
+         * add menu items to 2D-render any alignment or sequence secondary
+         * structure annotation
+         */
+        AlignmentAnnotation[] aas = ap.av.getAlignment()
                 .getAlignmentAnnotation();
-        for (int i = 0; aa != null && i < aa.length; i++)
+        if (aas != null)
         {
-          if (aa[i].isValidStruc() && aa[i].sequenceRef == null)
+          for (final AlignmentAnnotation aa : aas)
           {
-            final String rnastruc = aa[i].getRNAStruc();
-            final String structureLine = aa[i].label + " (alignment)";
-            menuItem = new JMenuItem();
-            menuItem.setText(MessageManager.formatMessage(
-                    "label.2d_rna_structure_line", new String[]
-                    { structureLine }));
-            menuItem.addActionListener(new java.awt.event.ActionListener()
+            if (aa.isValidStruc() && aa.sequenceRef == null)
             {
-              @Override
-              public void actionPerformed(ActionEvent e)
+              /*
+               * valid alignment RNA secondary structure annotation
+               */
+              menuItem = new JMenuItem();
+              menuItem.setText(MessageManager.formatMessage(
+                      "label.2d_rna_structure_line",
+                      new Object[] { aa.label }));
+              menuItem.addActionListener(new java.awt.event.ActionListener()
               {
-                // // System.out.println("1:"+structureLine);
-                // System.out.println("1:sname" + seq.getName());
-                // System.out.println("2:seq" + seq);
-                //
-                // // System.out.println("3:"+seq.getSequenceAsString());
-                // System.out.println("3:strucseq" + rnastruc);
-                // // System.out.println("4:struc"+seq.getRNA());
-                // System.out.println("5:name" + seq.getName());
-                // System.out.println("6:ap" + ap);
-                new AppVarna(structureLine, seq, seq.getSequenceAsString(),
-                        rnastruc, seq.getName(), ap);
-                // new AppVarna(seq.getName(),seq,rnastruc,seq.getRNA(),
-                // seq.getName(), ap);
-                System.out.println("end");
-              }
-            });
-            viewStructureMenu.add(menuItem);
+                @Override
+                public void actionPerformed(ActionEvent e)
+                {
+                  new AppVarna(seq, aa, ap);
+                }
+              });
+              rnaStructureMenu.add(menuItem);
+            }
           }
         }
 
-        // SequenceFeatures[] test = seq.getSequenceFeatures();
-
         if (seq.getAnnotation() != null)
         {
-          AlignmentAnnotation seqAnno[] = seq.getAnnotation();
-          for (int i = 0; i < seqAnno.length; i++)
+          AlignmentAnnotation seqAnns[] = seq.getAnnotation();
+          for (final AlignmentAnnotation aa : seqAnns)
           {
-            if (seqAnno[i].isValidStruc())
+            if (aa.isValidStruc())
             {
-              final String rnastruc = seqAnno[i].getRNAStruc();
-
+              /*
+               * valid sequence RNA secondary structure annotation
+               */
               // TODO: make rnastrucF a bit more nice
               menuItem = new JMenuItem();
               menuItem.setText(MessageManager.formatMessage(
-                      "label.2d_rna_sequence_name", new String[]
-                      { seq.getName() }));
+                      "label.2d_rna_sequence_name",
+                      new Object[] { seq.getName() }));
               menuItem.addActionListener(new java.awt.event.ActionListener()
               {
                 @Override
                 public void actionPerformed(ActionEvent e)
                 {
                   // TODO: VARNA does'nt print gaps in the sequence
-
-                  new AppVarna(seq.getName() + " structure", seq, seq
-                          .getSequenceAsString(), rnastruc, seq.getName(),
-                          ap);
+                  new AppVarna(seq, aa, ap);
                 }
               });
-              viewStructureMenu.add(menuItem);
+              rnaStructureMenu.add(menuItem);
             }
           }
         }
-
+        if (rnaStructureMenu.getItemCount() == origCount)
+        {
+          remove(rnaStructureMenu);
+        }
       }
 
       menuItem = new JMenuItem(
@@ -460,8 +415,8 @@ public class PopupMenu extends JPopupMenu
               && ap.av.getSelectionGroup().getSize() > 1)
       {
         menuItem = new JMenuItem(MessageManager.formatMessage(
-                "label.represent_group_with", new String[]
-                { seq.getName() }));
+                "label.represent_group_with",
+                new Object[] { seq.getName() }));
         menuItem.addActionListener(new java.awt.event.ActionListener()
         {
           @Override
@@ -529,8 +484,7 @@ public class PopupMenu extends JPopupMenu
     if (sg != null && sg.getSize() > 0)
     {
       groupName.setText(MessageManager.formatMessage("label.name_param",
-              new String[]
-              { sg.getName() }));
+              new Object[] { sg.getName() }));
       groupName.setText(MessageManager
               .getString("label.edit_name_and_description_current_group"));
 
@@ -610,7 +564,7 @@ public class PopupMenu extends JPopupMenu
       SequenceI sqass = null;
       for (SequenceI sq : ap.av.getSequenceSelection())
       {
-        Vector<PDBEntry> pes = sq.getDatasetSequence().getPDBId();
+        Vector<PDBEntry> pes = sq.getDatasetSequence().getAllPDBEntries();
         if (pes != null && pes.size() > 0)
         {
           reppdb.put(pes.get(0).getId(), pes.get(0));
@@ -630,50 +584,6 @@ public class PopupMenu extends JPopupMenu
                 new PDBEntry[pdbe.size()]), pr = reppdb.values().toArray(
                 new PDBEntry[reppdb.size()]);
         final JMenuItem gpdbview, rpdbview;
-        if (pdbe.size() == 1)
-        {
-          structureMenu.add(gpdbview = new JMenuItem(MessageManager
-                  .formatMessage("label.view_structure_for", new String[]
-                  { sqass.getDisplayId(false) })));
-        }
-        else
-        {
-          structureMenu.add(gpdbview = new JMenuItem(MessageManager
-                  .formatMessage("label.view_all_structures", new String[]
-                  { new Integer(pdbe.size()).toString() })));
-        }
-        gpdbview.setToolTipText(MessageManager
-                .getString("label.open_new_jmol_view_with_all_structures_associated_current_selection_superimpose_using_alignment"));
-        gpdbview.addActionListener(new ActionListener()
-        {
-
-          @Override
-          public void actionPerformed(ActionEvent e)
-          {
-            new StructureViewer(ap.getStructureSelectionManager())
-                    .viewStructures(ap, pe, ap.av.collateForPDB(pe));
-          }
-        });
-        if (reppdb.size() > 1 && reppdb.size() < pdbe.size())
-        {
-          structureMenu.add(rpdbview = new JMenuItem(MessageManager
-                  .formatMessage(
-                          "label.view_all_representative_structures",
-                          new String[]
-                          { new Integer(reppdb.size()).toString() })));
-          rpdbview.setToolTipText(MessageManager
-                  .getString("label.open_new_jmol_view_with_all_representative_structures_associated_current_selection_superimpose_using_alignment"));
-          rpdbview.addActionListener(new ActionListener()
-          {
-
-            @Override
-            public void actionPerformed(ActionEvent e)
-            {
-              new StructureViewer(ap.getStructureSelectionManager())
-                      .viewStructures(ap, pr, ap.av.collateForPDB(pr));
-            }
-          });
-        }
       }
     }
     else
@@ -698,7 +608,8 @@ public class PopupMenu extends JPopupMenu
     if (seq == null)
     {
       sequenceMenu.setVisible(false);
-      structureMenu.setVisible(false);
+      pdbStructureDialog.setVisible(false);
+      rnaStructureMenu.setVisible(false);
     }
 
     if (links != null && links.size() > 0)
@@ -731,8 +642,7 @@ public class PopupMenu extends JPopupMenu
 
           // collect matching db-refs
           DBRefEntry[] dbr = jalview.util.DBRefUtils.selectRefs(
-                  seq.getDBRef(), new String[]
-                  { urlLink.getTarget() });
+                  seq.getDBRef(), new String[] { urlLink.getTarget() });
           // collect id string too
           String id = seq.getName();
           String descr = seq.getDescription();
@@ -863,17 +773,15 @@ public class PopupMenu extends JPopupMenu
      */
     Map<String, List<List<String>>> shownTypes = new LinkedHashMap<String, List<List<String>>>();
     Map<String, List<List<String>>> hiddenTypes = new LinkedHashMap<String, List<List<String>>>();
-    AlignmentAnnotationUtils.getShownHiddenTypes(shownTypes,
-            hiddenTypes,
-            AlignmentAnnotationUtils.asList(annotations),
-            forSequences);
+    AlignmentAnnotationUtils.getShownHiddenTypes(shownTypes, hiddenTypes,
+            AlignmentAnnotationUtils.asList(annotations), forSequences);
 
     for (String calcId : hiddenTypes.keySet())
     {
       for (List<String> type : hiddenTypes.get(calcId))
       {
-        addAnnotationTypeToShowHide(showMenu, forSequences,
-                calcId, type, false, true);
+        addAnnotationTypeToShowHide(showMenu, forSequences, calcId, type,
+                false, true);
       }
     }
     // grey out 'show annotations' if none are hidden
@@ -883,8 +791,8 @@ public class PopupMenu extends JPopupMenu
     {
       for (List<String> type : shownTypes.get(calcId))
       {
-        addAnnotationTypeToShowHide(hideMenu, forSequences,
-                calcId, type, false, false);
+        addAnnotationTypeToShowHide(hideMenu, forSequences, calcId, type,
+                false, false);
       }
     }
     // grey out 'hide annotations' if none are shown
@@ -937,7 +845,7 @@ public class PopupMenu extends JPopupMenu
           final boolean actionIsShow)
   {
     String label = types.toString(); // [a, b, c]
-    label = label.substring(1, label.length() - 1);
+    label = label.substring(1, label.length() - 1); // a, b, c
     final JMenuItem item = new JMenuItem(label);
     item.setToolTipText(calcId);
     item.addActionListener(new java.awt.event.ActionListener()
@@ -945,41 +853,14 @@ public class PopupMenu extends JPopupMenu
       @Override
       public void actionPerformed(ActionEvent e)
       {
-        showHideAnnotation_actionPerformed(types, forSequences, allTypes,
-                actionIsShow);
+        AlignmentUtils.showOrHideSequenceAnnotations(ap.getAlignment(),
+                types, forSequences, allTypes, actionIsShow);
+        refresh();
       }
     });
     showOrHideMenu.add(item);
   }
 
-  /**
-   * Action on selecting a list of annotation type (or the 'all types' values)
-   * to show or hide for the specified sequences.
-   * 
-   * @param types
-   * @param forSequences
-   * @param anyType
-   * @param doShow
-   */
-  protected void showHideAnnotation_actionPerformed(
-          Collection<String> types, List<SequenceI> forSequences,
-          boolean anyType, boolean doShow)
-  {
-    for (AlignmentAnnotation aa : ap.getAlignment()
-            .getAlignmentAnnotation())
-    {
-      if (anyType || types.contains(aa.label))
-      {
-        if ((aa.sequenceRef != null)
-                && forSequences.contains(aa.sequenceRef))
-        {
-          aa.visible = doShow;
-        }
-      }
-    }
-    refresh();
-  }
-
   private void buildGroupURLMenu(SequenceGroup sg, Vector groupLinks)
   {
 
@@ -989,8 +870,8 @@ public class PopupMenu extends JPopupMenu
     // ID/regex match URLs
     groupLinksMenu = new JMenu(
             MessageManager.getString("action.group_link"));
-    JMenu[] linkMenus = new JMenu[]
-    { null, new JMenu(MessageManager.getString("action.ids")),
+    JMenu[] linkMenus = new JMenu[] { null,
+        new JMenu(MessageManager.getString("action.ids")),
         new JMenu(MessageManager.getString("action.sequences")),
         new JMenu(MessageManager.getString("action.ids_sequences")) }; // three
                                                                        // types
@@ -1025,8 +906,7 @@ public class PopupMenu extends JPopupMenu
           if (sarray == null)
           {
             sarray = new Object[2];
-            sarray[0] = new int[]
-            { 0 };
+            sarray[0] = new int[] { 0 };
             sarray[1] = new String[seqs.length];
 
             commonDbrefs.put(src, sarray);
@@ -1107,8 +987,6 @@ public class PopupMenu extends JPopupMenu
       if (urlset != null)
       {
         int type = urlLink.getGroupURLType() & 3;
-        // System.out.println(urlLink.getGroupURLType()
-        // +" "+((String[])urlset[3])[0]);
         // first two bits ofurlLink type bitfield are sequenceids and sequences
         // TODO: FUTURE: ensure the groupURL menu structure can be generalised
         addshowLink(linkMenus[type], label
@@ -1148,8 +1026,7 @@ public class PopupMenu extends JPopupMenu
   {
     JMenuItem item = new JMenuItem(label);
     item.setToolTipText(MessageManager.formatMessage(
-            "label.open_url_param", new String[]
-            { url }));
+            "label.open_url_param", new Object[] { url }));
     item.addActionListener(new java.awt.event.ActionListener()
     {
       @Override
@@ -1188,8 +1065,7 @@ public class PopupMenu extends JPopupMenu
     JMenuItem item = new JMenuItem(label);
     item.setToolTipText(MessageManager.formatMessage(
             "label.open_url_seqs_param",
-            new Object[]
-            { urlgenerator.getUrl_prefix(),
+            new Object[] { urlgenerator.getUrl_prefix(),
                 urlgenerator.getNumberInvolved(urlstub) }));
     // TODO: put in info about what is being sent.
     item.addActionListener(new java.awt.event.ActionListener()
@@ -1249,7 +1125,7 @@ public class PopupMenu extends JPopupMenu
       }
     });
     chooseAnnotations.setText(MessageManager
-            .getString("label.choose_annotations") + "...");
+            .getString("action.choose_annotations"));
     chooseAnnotations.addActionListener(new java.awt.event.ActionListener()
     {
       @Override
@@ -1259,7 +1135,7 @@ public class PopupMenu extends JPopupMenu
       }
     });
     sequenceDetails.setText(MessageManager
-            .getString("label.sequence_details") + "...");
+            .getString("label.sequence_details"));
     sequenceDetails.addActionListener(new java.awt.event.ActionListener()
     {
       @Override
@@ -1269,7 +1145,7 @@ public class PopupMenu extends JPopupMenu
       }
     });
     sequenceSelDetails.setText(MessageManager
-            .getString("label.sequence_details") + "...");
+            .getString("label.sequence_details"));
     sequenceSelDetails
             .addActionListener(new java.awt.event.ActionListener()
             {
@@ -1419,32 +1295,7 @@ public class PopupMenu extends JPopupMenu
         pdbFromFile_actionPerformed();
       }
     });
-    // RNAFold.setText("From RNA Fold with predict2D");
-    // RNAFold.addActionListener(new ActionListener()
-    // {
-    // public void actionPerformed(ActionEvent e)
-    // {
-    // try {
-    // RNAFold_actionPerformed();
-    // } catch (Exception e1) {
-    // // TODO Auto-generated catch block
-    // e1.printStackTrace();
-    // }
-    // }
-    // });
-    // ContraFold.setText("From Contra Fold with predict2D");
-    // ContraFold.addActionListener(new ActionListener()
-    // {
-    // public void actionPerformed(ActionEvent e)
-    // {
-    // try {
-    // ContraFold_actionPerformed();
-    // } catch (Exception e1) {
-    // // TODO Auto-generated catch block
-    // e1.printStackTrace();
-    // }
-    // }
-    // });
+
     enterPDB.setText(MessageManager.getString("label.enter_pdb_id"));
     enterPDB.addActionListener(new ActionListener()
     {
@@ -1493,9 +1344,25 @@ public class PopupMenu extends JPopupMenu
       }
     });
     jMenu1.setText(MessageManager.getString("label.group"));
-    structureMenu.setText(MessageManager.getString("label.structure"));
-    viewStructureMenu.setText(MessageManager
-            .getString("label.view_structure"));
+    pdbStructureDialog.setText(MessageManager
+            .getString("label.show_pdbstruct_dialog"));
+    pdbStructureDialog.addActionListener(new ActionListener()
+    {
+      @Override
+      public void actionPerformed(ActionEvent actionEvent)
+      {
+        SequenceI[] selectedSeqs = new SequenceI[] { sequence };
+        if (ap.av.getSelectionGroup() != null)
+        {
+          selectedSeqs = ap.av.getSequenceSelection();
+        }
+        new StructureChooser(selectedSeqs, sequence, ap);
+      }
+    });
+
+    rnaStructureMenu.setText(MessageManager
+            .getString("label.view_rna_structure"));
+
     // colStructureMenu.setText("Colour By Structure");
     editSequence.setText(MessageManager.getString("label.edit_sequence")
             + "...");
@@ -1507,7 +1374,29 @@ public class PopupMenu extends JPopupMenu
         editSequence_actionPerformed(actionEvent);
       }
     });
+    makeReferenceSeq.setText(MessageManager
+            .getString("label.mark_as_representative"));
+    makeReferenceSeq.addActionListener(new ActionListener()
+    {
 
+      @Override
+      public void actionPerformed(ActionEvent actionEvent)
+      {
+        makeReferenceSeq_actionPerformed(actionEvent);
+
+      }
+    });
+    hideInsertions.setText(MessageManager
+            .getString("label.hide_insertions"));
+    hideInsertions.addActionListener(new ActionListener()
+    {
+
+      @Override
+      public void actionPerformed(ActionEvent e)
+      {
+        hideInsertions_actionPerformed(e);
+      }
+    });
     /*
      * annotationMenuItem.setText("By Annotation");
      * annotationMenuItem.addActionListener(new ActionListener() { public void
@@ -1517,7 +1406,12 @@ public class PopupMenu extends JPopupMenu
     groupMenu.add(sequenceSelDetails);
     add(groupMenu);
     add(sequenceMenu);
-    this.add(structureMenu);
+    add(rnaStructureMenu);
+    add(pdbStructureDialog);
+    if (sequence != null)
+    {
+      add(hideInsertions);
+    }
     // annotations configuration panel suppressed for now
     // groupMenu.add(chooseAnnotations);
 
@@ -1539,6 +1433,7 @@ public class PopupMenu extends JPopupMenu
     groupMenu.add(jMenu1);
     sequenceMenu.add(sequenceName);
     sequenceMenu.add(sequenceDetails);
+    sequenceMenu.add(makeReferenceSeq);
     colourMenu.add(textColour);
     colourMenu.add(noColourmenuItem);
     colourMenu.add(clustalColour);
@@ -1555,10 +1450,8 @@ public class PopupMenu extends JPopupMenu
     if (ap.getAlignment().isNucleotide())
     {
       // JBPNote - commented since the colourscheme isn't functional
-      // colourMenu.add(RNAInteractionColour);
       colourMenu.add(purinePyrimidineColour);
     }
-    // colourMenu.add(covariationColour);
     colourMenu.add(userDefinedColour);
 
     if (jalview.gui.UserDefinedColours.getUserColourSchemes() != null)
@@ -1584,7 +1477,6 @@ public class PopupMenu extends JPopupMenu
     colourMenu.addSeparator();
     colourMenu.add(abovePIDColour);
     colourMenu.add(conservationMenuItem);
-    // colourMenu.add(annotationMenuItem);
     editMenu.add(copy);
     editMenu.add(cut);
     editMenu.add(editSequence);
@@ -1605,9 +1497,6 @@ public class PopupMenu extends JPopupMenu
     jMenu1.add(showColourText);
     jMenu1.add(outline);
     jMenu1.add(displayNonconserved);
-    structureMenu.add(pdbMenu);
-    structureMenu.add(viewStructureMenu);
-    // structureMenu.add(colStructureMenu);
     noColourmenuItem.setText(MessageManager.getString("label.none"));
     noColourmenuItem.addActionListener(new java.awt.event.ActionListener()
     {
@@ -1777,71 +1666,25 @@ public class PopupMenu extends JPopupMenu
    * @param menuItem
    * @param forSequences
    */
-  protected void configureReferenceAnnotationsMenu(
-          JMenuItem menuItem, List<SequenceI> forSequences)
+  protected void configureReferenceAnnotationsMenu(JMenuItem menuItem,
+          List<SequenceI> forSequences)
   {
-    menuItem.setText(MessageManager
-            .getString("label.add_reference_annotations"));
     menuItem.setEnabled(false);
-    if (forSequences == null)
-    {
-      return;
-    }
 
     /*
      * Temporary store to hold distinct calcId / type pairs for the tooltip.
      * Using TreeMap means calcIds are shown in alphabetical order.
      */
     Map<String, String> tipEntries = new TreeMap<String, String>();
-    StringBuilder tooltip = new StringBuilder(64);
-    tooltip.append(MessageManager.getString("label.add_annotations_for"));
-
-    /*
-     * For each sequence selected in the alignment, make a list of any
-     * annotations on the underlying dataset sequence which are not already on
-     * the alignment.
-     * 
-     * Build a map of { alignmentSequence, <List of annotations to add> }
-     */
-    AlignmentI al = this.ap.av.getAlignment();
     final Map<SequenceI, List<AlignmentAnnotation>> candidates = new LinkedHashMap<SequenceI, List<AlignmentAnnotation>>();
-    for (SequenceI seq : forSequences)
-    {
-      SequenceI dataset = seq.getDatasetSequence();
-      if (dataset == null)
-      {
-        continue;
-      }
-      AlignmentAnnotation[] datasetAnnotations = dataset.getAnnotation();
-      if (datasetAnnotations == null)
-      {
-        continue;
-      }
-      final List<AlignmentAnnotation> result = new ArrayList<AlignmentAnnotation>();
-      for (AlignmentAnnotation dsann : datasetAnnotations)
-      {
-        /*
-         * Find matching annotations on the alignment.
-         */
-        final Iterable<AlignmentAnnotation> matchedAlignmentAnnotations = al
-                .findAnnotations(seq, dsann.getCalcId(),
-                        dsann.label);
-        if (!matchedAlignmentAnnotations.iterator().hasNext())
-        {
-          result.add(dsann);
-          tipEntries.put(dsann.getCalcId(), dsann.label);
-        }
-      }
-      /*
-       * Save any addable annotations for this sequence
-       */
-      if (!result.isEmpty())
-      {
-        candidates.put(seq, result);
-      }
-    }
+    AlignmentI al = this.ap.av.getAlignment();
+    AlignmentUtils.findAddableReferenceAnnotations(forSequences,
+            tipEntries, candidates, al);
     if (!candidates.isEmpty())
     {
+      StringBuilder tooltip = new StringBuilder(64);
+      tooltip.append(MessageManager.getString("label.add_annotations_for"));
+
       /*
        * Found annotations that could be added. Enable the menu item, and
        * configure its tooltip and action.
@@ -1876,39 +1719,47 @@ public class PopupMenu extends JPopupMenu
   protected void addReferenceAnnotations_actionPerformed(
           Map<SequenceI, List<AlignmentAnnotation>> candidates)
   {
-    /*
-     * Add annotations at the top of the annotation, in the same order as their
-     * related sequences.
-     */
-    for (SequenceI seq : candidates.keySet())
+    final SequenceGroup selectionGroup = this.ap.av.getSelectionGroup();
+    final AlignmentI alignment = this.ap.getAlignment();
+    AlignmentUtils.addReferenceAnnotations(candidates, alignment,
+            selectionGroup);
+    refresh();
+  }
+
+  protected void makeReferenceSeq_actionPerformed(ActionEvent actionEvent)
+  {
+    if (!ap.av.getAlignment().hasSeqrep())
     {
-      for (AlignmentAnnotation ann : candidates.get(seq))
+      // initialise the display flags so the user sees something happen
+      ap.av.setDisplayReferenceSeq(true);
+      ap.av.setColourByReferenceSeq(true);
+      ap.av.getAlignment().setSeqrep(sequence);
+    }
+    else
+    {
+      if (ap.av.getAlignment().getSeqrep() == sequence)
       {
-        AlignmentAnnotation copyAnn = new AlignmentAnnotation(ann);
-        int startRes = 0;
-        int endRes = ann.annotations.length;
-        final SequenceGroup selectionGroup = this.ap.av.getSelectionGroup();
-        if (selectionGroup != null)
-        {
-          startRes = selectionGroup.getStartRes();
-          endRes = selectionGroup.getEndRes();
-        }
-        copyAnn.restrict(startRes, endRes);
+        ap.av.getAlignment().setSeqrep(null);
+      }
+      else
+      {
+        ap.av.getAlignment().setSeqrep(sequence);
+      }
+    }
+    refresh();
+  }
 
-        /*
-         * Add to the sequence (sets copyAnn.datasetSequence), unless the
-         * original annotation is already on the sequence.
-         */
-        if (!seq.hasAnnotation(ann))
-        {
-          seq.addAlignmentAnnotation(copyAnn);
-        }
-        // adjust for gaps
-        copyAnn.adjustForAlignment();
-        // add to the alignment and set visible
-        this.ap.getAlignment().addAnnotation(copyAnn);
-        copyAnn.visible = true;
+  protected void hideInsertions_actionPerformed(ActionEvent actionEvent)
+  {
+    if (sequence != null)
+    {
+      ColumnSelection cs = ap.av.getColumnSelection();
+      if (cs == null)
+      {
+        cs = new ColumnSelection();
       }
+      cs.hideInsertionsFor(sequence);
+      ap.av.setColumnSelection(cs);
     }
     refresh();
   }
@@ -1920,8 +1771,7 @@ public class PopupMenu extends JPopupMenu
 
   protected void sequenceDetails_actionPerformed()
   {
-    createSequenceDetailsReport(new SequenceI[]
-    { sequence });
+    createSequenceDetailsReport(new SequenceI[] { sequence });
   }
 
   public void createSequenceDetailsReport(SequenceI[] sequences)
@@ -1934,8 +1784,8 @@ public class PopupMenu extends JPopupMenu
               + MessageManager
                       .formatMessage(
                               "label.create_sequence_details_report_annotation_for",
-                              new String[]
-                              { seq.getDisplayId(true) }) + "</h2></p><p>");
+                              new Object[] { seq.getDisplayId(true) })
+              + "</h2></p><p>");
       new SequenceAnnotationReport(null)
               .createSequenceAnnotationReport(
                       contents,
@@ -1944,18 +1794,17 @@ public class PopupMenu extends JPopupMenu
                       true,
                       false,
                       (ap.getSeqPanel().seqCanvas.fr != null) ? ap
-                              .getSeqPanel().seqCanvas.fr
-                              .getMinMax()
+                              .getSeqPanel().seqCanvas.fr.getMinMax()
                               : null);
       contents.append("</p>");
     }
     cap.setText("<html>" + contents.toString() + "</html>");
 
-    Desktop.instance.addInternalFrame(cap, MessageManager.formatMessage(
-            "label.sequece_details_for",
-            (sequences.length == 1 ? new String[]
-            { sequences[0].getDisplayId(true) } : new String[]
-            { MessageManager.getString("label.selection") })), 500, 400);
+    Desktop.addInternalFrame(cap, MessageManager.formatMessage(
+            "label.sequence_details_for",
+            (sequences.length == 1 ? new Object[] { sequences[0]
+                    .getDisplayId(true) } : new Object[] { MessageManager
+                    .getString("label.selection") })), 500, 400);
 
   }
 
@@ -2118,14 +1967,14 @@ public class PopupMenu extends JPopupMenu
       int threshold = SliderPanel.setPIDSliderSource(ap, sg.cs, getGroup()
               .getName());
 
-      sg.cs.setThreshold(threshold, ap.av.getIgnoreGapsConsensus());
+      sg.cs.setThreshold(threshold, ap.av.isIgnoreGapsConsensus());
 
       SliderPanel.showPIDSlider();
     }
     else
     // remove PIDColouring
     {
-      sg.cs.setThreshold(0, ap.av.getIgnoreGapsConsensus());
+      sg.cs.setThreshold(0, ap.av.isIgnoreGapsConsensus());
     }
 
     refresh();
@@ -2461,8 +2310,7 @@ public class PopupMenu extends JPopupMenu
     SequenceGroup sg = ap.av.getSelectionGroup();
     if (sg == null || sg.getSize() < 1)
     {
-      ap.av.hideSequence(new SequenceI[]
-      { sequence });
+      ap.av.hideSequence(new SequenceI[] { sequence });
       return;
     }
 
@@ -2476,15 +2324,7 @@ public class PopupMenu extends JPopupMenu
     }
 
     int gsize = sg.getSize();
-    SequenceI[] hseqs;
-
-    hseqs = new SequenceI[gsize];
-
-    int index = 0;
-    for (int i = 0; i < gsize; i++)
-    {
-      hseqs[index++] = sg.getSequenceAt(i);
-    }
+    SequenceI[] hseqs = sg.getSequences().toArray(new SequenceI[gsize]);
 
     ap.av.hideSequence(hseqs);
     // refresh(); TODO: ? needed ?
@@ -2508,8 +2348,8 @@ public class PopupMenu extends JPopupMenu
 
     if (sg != null)
     {
-      int[][] startEnd = ap.av.getVisibleRegionBoundaries(sg.getStartRes(),
-              sg.getEndRes() + 1);
+      List<int[]> startEnd = ap.av.getVisibleRegionBoundaries(
+              sg.getStartRes(), sg.getEndRes() + 1);
 
       String description;
       int caseChange;
@@ -2547,8 +2387,8 @@ public class PopupMenu extends JPopupMenu
     CutAndPasteTransfer cap = new CutAndPasteTransfer();
     cap.setForInput(null);
     Desktop.addInternalFrame(cap, MessageManager.formatMessage(
-            "label.alignment_output_command", new String[]
-            { e.getActionCommand() }), 600, 500);
+            "label.alignment_output_command",
+            new Object[] { e.getActionCommand() }), 600, 500);
 
     String[] omitHidden = null;
 
@@ -2556,8 +2396,8 @@ public class PopupMenu extends JPopupMenu
     // or we simply trust the user wants
     // wysiwig behaviour
 
-    cap.setText(new FormatAdapter().formatSequences(e.getActionCommand(),
-            ap.av, true));
+    cap.setText(new FormatAdapter(ap).formatSequences(e.getActionCommand(),
+            ap, true));
   }
 
   public void pdbFromFile_actionPerformed()
@@ -2566,11 +2406,11 @@ public class PopupMenu extends JPopupMenu
             jalview.bin.Cache.getProperty("LAST_DIRECTORY"));
     chooser.setFileView(new jalview.io.JalviewFileView());
     chooser.setDialogTitle(MessageManager.formatMessage(
-            "label.select_pdb_file_for", new String[]
-            { sequence.getDisplayId(false) }));
+            "label.select_pdb_file_for",
+            new Object[] { sequence.getDisplayId(false) }));
     chooser.setToolTipText(MessageManager.formatMessage(
-            "label.load_pdb_file_associate_with_sequence", new String[]
-            { sequence.getDisplayId(false) }));
+            "label.load_pdb_file_associate_with_sequence",
+            new Object[] { sequence.getDisplayId(false) }));
 
     int value = chooser.showOpenDialog(null);
 
@@ -2585,18 +2425,6 @@ public class PopupMenu extends JPopupMenu
 
   }
 
-  // JBNote: commented out - these won't be instantiated here...!
-  // public void RNAFold_actionPerformed() throws Exception
-  // {
-  // Predict2D P2D = new Predict2D();
-  // P2D.getStructure2DFromRNAFold("toto");
-  // }
-  //
-  // public void ContraFold_actionPerformed() throws Exception
-  // {
-  // Predict2D P2D = new Predict2D();
-  // P2D.getStructure2DFromContraFold("toto");
-  // }
   public void enterPDB_actionPerformed()
   {
     String id = JOptionPane.showInternalInputDialog(Desktop.desktop,