Merge branch 'Jalview-BH/JAL-3026-JAL-3063-JAXB' of https://source.jalview.org/git...
authorgmungoc <g.m.carstairs@dundee.ac.uk>
Tue, 29 Jan 2019 11:33:12 +0000 (11:33 +0000)
committergmungoc <g.m.carstairs@dundee.ac.uk>
Tue, 29 Jan 2019 11:33:12 +0000 (11:33 +0000)
17 files changed:
optimization/full-profile-ENSG000000157764-to-display-chrome.txt [new file with mode: 0644]
optimization/full-profile-ENSG000000157764-to-display-ff.txt [new file with mode: 0644]
optimization/timing-js-chrome-bh-3.txt [new file with mode: 0644]
optimization/timing-js-firefox-bh-3.txt [new file with mode: 0644]
src/jalview/datamodel/Alignment.java
src/jalview/ext/ensembl/EnsemblRestClient.java
src/jalview/ext/ensembl/EnsemblSeqProxy.java
src/jalview/gui/Desktop.java
src/jalview/javascript/json/JSON.java
src/jalview/util/Platform.java
swingjs/SwingJS-site.zip
swingjs/timestamp
swingjs/ver/3.2.4/SwingJS-site.zip
swingjs/ver/3.2.4/timestamp
unused/AlignmentAnnotation.java [new file with mode: 0644]
unused/MapList.java [new file with mode: 0644]
unused/Mapping.java [new file with mode: 0644]

diff --git a/optimization/full-profile-ENSG000000157764-to-display-chrome.txt b/optimization/full-profile-ENSG000000157764-to-display-chrome.txt
new file mode 100644 (file)
index 0000000..ae9c4cc
--- /dev/null
@@ -0,0 +1,511 @@
+ Total new objects: 3207143
+
+count          exec(ms)
+--------       --------        ------------------------------
+...2100182     ....-24750              undefined[]
+....504006     ......2661              java.lang.StringBuilder
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+....205602     .......427              jalview.datamodel.Profile
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+....170025     .....-2281              Object[]
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+....138605     .......377              swingjs.json.JSON.JSONList
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+....107812     ......3263              jalview.datamodel.SequenceFeature
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+.....46224     ........94              swingjs.json.JSON.JSONList.ListIterator
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+......3870     ........10              jalview.analysis.AlignmentUtils.DnaVariant
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+.........1     .........0              jalview.jbgui.GAlignFrame$101
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+.........1     .........0              jalview.jbgui.GAlignFrame$10
+.........1     .........0              jalview.io.SequenceAnnotationReport$1
+.........1     .........0              jalview.io.FileFormat[]
+.........1     .........0              jalview.io.FileFormat$9
+.........1     .........0              jalview.io.FileFormat$8
+.........1     .........0              jalview.io.FileFormat$7
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+.........1     .........0              jalview.io.FileFormat$14
+.........1     .........0              jalview.io.FileFormat$13
+.........1     .........0              jalview.io.FileFormat$12
+.........1     .........0              jalview.io.FileFormat$11
+.........1     .........0              jalview.io.FileFormat$10
+.........1     .........0              jalview.io.FileFormat$1
+.........1     .........0              jalview.gui.ViewSelectionMenu$1
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+.........1     .........0              jalview.gui.Desktop$12
+.........1     .........0              jalview.gui.Desktop$11
+.........1     .........0              jalview.gui.ColourMenuHelper$4
+.........1     .........0              jalview.gui.ColourMenuHelper$1
+.........1     .........0              jalview.gui.AnnotationPanel.DragMode[]
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+.........1     .........0              jalview.gui.AlignmentPanel$1
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+.........1     .........0              jalview.gui.AlignFrame$1
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+.........1     .........0              jalview.ext.ensembl.EnsemblGene$1$2
+.........1     .........0              jalview.ext.ensembl.EnsemblGene$1$1
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+.........1     .........0              jalview.analysis.AnnotationSorter.SequenceAnnotationOrder[]
+.........1     ........-1              jalview.datamodel.ProfileI[]
+...5993224     .....61225      
\ No newline at end of file
diff --git a/optimization/full-profile-ENSG000000157764-to-display-ff.txt b/optimization/full-profile-ENSG000000157764-to-display-ff.txt
new file mode 100644 (file)
index 0000000..0d48473
--- /dev/null
@@ -0,0 +1,514 @@
+"run  Clazz.startProfiling() first
+
+ Total new objects: 3208398
+
+count          exec(ms)
+--------       --------        ------------------------------
+...2100232     ....-40921              undefined[]
+....504006     .....12402              java.lang.StringBuilder
+....436605     ......3414              java.util.HashMap.Node
+....411205     ......2841              jalview.datamodel.Annotation
+....232907     ......1122              Float
+....215619     ......2440              jalview.datamodel.features.FeatureStore$SearchCriterion$3
+....206107     ......1241              java.awt.Color
+....206007     ......1059              Integer
+....205602     ......3110              jalview.datamodel.ResidueCount
+....205602     ......1697              jalview.datamodel.Profile
+....172921     ......3075              java.util.ArrayList.Itr
+....170314     .....-3144              Object[]
+....139806     .......457              Long
+....138605     ......1033              swingjs.json.JSON.JSONList
+....108563     ......1065              java.util.HashMap
+....108553     .....-2025              java.util.HashMap.Node[]
+....107812     ......9397              jalview.datamodel.SequenceFeature
+.....79143     ......1124              java.util.ArrayList
+.....61212     ......1423              java.util.HashMap.EntryIterator
+.....52231     ......1485              java.util.HashMap.EntrySet
+.....47591     .......876              swingjs.json.JSON.JSONMap
+.....46224     .......266              swingjs.json.JSON.JSONList.ListIterator
+......7084     .......450              jalview.datamodel.features.NCNode
+......3870     ........33              jalview.analysis.AlignmentUtils.DnaVariant
+......3076     ........96              java.awt.Dimension
+......2153     ........43              java.beans.PropertyChangeEvent
+......1561     ........13              jalview.datamodel.SequenceCursor
+......1356     ........18              java.util.LinkedHashMap.Entry
+......1329     .......105              jalview.datamodel.features.NCList
+......1290     .......-22              java.util.ArrayList[]
+.......687     .........9              java.util.Hashtable.Entry
+.......684     ........16              jalview.datamodel.DBRefEntry
+.......526     ........16              javajs.util.Lst
+.......505     ........21              java.util.TreeMap.ValueIterator
+.......479     .........9              javax.swing.event.EventListenerList
+.......449     ........19              java.util.HashSet
+.......449     .........9              java.util.ArrayList$SubList$1
+.......449     .........8              java.util.ArrayList.SubList
+.......440     .........0              jalview.datamodel.HiddenCursorPosition
+.......402     ........-8              java.lang.Class[]
+.......346     .........4              java.awt.geom.AffineTransform
+.......346     .........4              java.awt.BasicStroke
+.......325     ........28              java.awt.EventDispatchThread$1
+.......290     ........-7              java.beans.PropertyChangeListener[]
+.......287     ........11              java.util.Hashtable.Enumerator
+.......280     .........5              java.awt.Rectangle
+.......276     .........7              java.util.TreeMap.EntryIterator
+.......274     ........-7              java.awt.Component[]
+.......261     ........10              java.beans.PropertyChangeSupport
+.......261     .........6              java.beans.PropertyChangeSupport.PropertyChangeListenerMap
+.......226     .........3              java.util.Collections.UnmodifiableSet
+.......219     .........1              com.stevesoft.pat.StrPos
+.......206     .........5              java.awt.AWTEventMulticaster
+.......200     .........5              java.util.HashMap.KeySet
+.......200     .........5              java.util.HashMap.KeyIterator
+.......199     ........35              java.awt.EventDispatchThread
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+.......198     .........2              javax.swing.plaf.ComponentInputMapUIResource
+.......187     .........3              java.util.Arrays.ArrayList
+.......182     ........14              java.awt.event.ContainerEvent
+.......176     ........-7              java.util.Hashtable.Entry[]
+.......173     .........2              javax.swing.ActionMap
+.......173     ........-5              javax.swing.KeyStroke[]
+.......171     .........3              java.awt.Insets
+.......169     .........6              javax.swing.AbstractButton.Handler
+.......169     .........5              javax.swing.JMenuItem.MenuItemFocusListener
+.......169     .........2              swingjs.plaf.ButtonListener
+.......154     .........4              javax.swing.KeyboardManager.ComponentKeyStrokePair
+.......145     ........14              java.awt.event.MouseEvent
+.......138     .........1              jalview.datamodel.PDBEntry
+.......136     .........5              java.util.Vector.Itr
+.......132     .........2              javajs.util.SB
+.......126     .........3              java.awt.EventQueueItem
+.......122     .........6              java.io.ByteArrayInputStream
+.......122     .........6              java.io.BufferedInputStream
+.......116     .........1              javax.swing.DefaultButtonModel
+.......112     .........6              java.lang.StringBuffer
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+........94     .......690              javax.swing.JMenuItem
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+........67     .......176              jalview.datamodel.Sequence
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+........67     .........7              java.net.URL
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+........60     .........4              java.util.Collections$UnmodifiableCollection$1
+........60     .........0              javax.swing.SizeRequirements
+........55     .......163              swingjs.json.JSON.JSONReader
+........53     .........5              java.util.ArrayList.ListItr
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+........39     .........5              jalview.datamodel.HiddenColumnsCursor
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+........35     .......169              javax.swing.JCheckBoxMenuItem
+........34     ........11              jalview.util.MapList
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+.........1     .........0              jalview.jbgui.GAlignFrame$24
+.........1     .........0              jalview.jbgui.GAlignFrame$22
+.........1     .........0              jalview.jbgui.GAlignFrame$20
+.........1     .........0              jalview.jbgui.GAlignFrame$2
+.........1     .........0              jalview.jbgui.GAlignFrame$19
+.........1     .........0              jalview.jbgui.GAlignFrame$18
+.........1     .........0              jalview.jbgui.GAlignFrame$17
+.........1     .........0              jalview.jbgui.GAlignFrame$16
+.........1     .........0              jalview.jbgui.GAlignFrame$15
+.........1     .........0              jalview.jbgui.GAlignFrame$121
+.........1     .........0              jalview.jbgui.GAlignFrame$120
+.........1     .........0              jalview.jbgui.GAlignFrame$12
+.........1     .........0              jalview.jbgui.GAlignFrame$119
+.........1     .........0              jalview.jbgui.GAlignFrame$118
+.........1     .........0              jalview.jbgui.GAlignFrame$117
+.........1     .........0              jalview.jbgui.GAlignFrame$115
+.........1     .........0              jalview.jbgui.GAlignFrame$114
+.........1     .........0              jalview.jbgui.GAlignFrame$113
+.........1     .........0              jalview.jbgui.GAlignFrame$112
+.........1     .........0              jalview.jbgui.GAlignFrame$111
+.........1     .........0              jalview.jbgui.GAlignFrame$110
+.........1     .........0              jalview.jbgui.GAlignFrame$11
+.........1     .........0              jalview.jbgui.GAlignFrame$109
+.........1     .........0              jalview.jbgui.GAlignFrame$108
+.........1     .........0              jalview.jbgui.GAlignFrame$107
+.........1     .........0              jalview.jbgui.GAlignFrame$106
+.........1     .........0              jalview.jbgui.GAlignFrame$105
+.........1     .........0              jalview.jbgui.GAlignFrame$104
+.........1     .........0              jalview.jbgui.GAlignFrame$103
+.........1     .........0              jalview.jbgui.GAlignFrame$101
+.........1     .........0              jalview.jbgui.GAlignFrame$100
+.........1     .........0              jalview.jbgui.GAlignFrame$10
+.........1     .........0              jalview.io.FileFormat[]
+.........1     .........0              jalview.io.FileFormat$9
+.........1     .........0              jalview.io.FileFormat$8
+.........1     .........0              jalview.io.FileFormat$7
+.........1     .........0              jalview.io.FileFormat$6
+.........1     .........0              jalview.io.FileFormat$5
+.........1     .........0              jalview.io.FileFormat$4
+.........1     .........0              jalview.io.FileFormat$2
+.........1     .........0              jalview.io.FileFormat$19
+.........1     .........0              jalview.io.FileFormat$18
+.........1     .........0              jalview.io.FileFormat$17
+.........1     .........0              jalview.io.FileFormat$16
+.........1     .........0              jalview.io.FileFormat$15
+.........1     .........0              jalview.io.FileFormat$14
+.........1     .........0              jalview.io.FileFormat$12
+.........1     .........0              jalview.io.FileFormat$11
+.........1     .........0              jalview.io.FileFormat$10
+.........1     .........0              jalview.io.FileFormat$1
+.........1     .........0              jalview.gui.ViewSelectionMenu$1
+.........1     .........0              jalview.gui.Desktop$13
+.........1     .........0              jalview.gui.Desktop$12
+.........1     .........0              jalview.gui.Desktop$11
+.........1     .........0              jalview.gui.ColourMenuHelper$4
+.........1     .........0              jalview.gui.AnnotationPanel.DragMode[]
+.........1     .........0              jalview.gui.AlignmentPanel$2
+.........1     .........0              jalview.gui.AlignmentPanel$1
+.........1     .........0              jalview.gui.AlignFrame$5
+.........1     .........0              jalview.gui.AlignFrame$4
+.........1     .........0              jalview.gui.AlignFrame$20
+.........1     .........0              jalview.gui.AlignFrame$2
+.........1     .........0              jalview.gui.AlignFrame$1
+.........1     .........0              jalview.ext.ensembl.EnsemblSeqProxy.EnsemblSeqType[]
+.........1     .........0              jalview.ext.ensembl.EnsemblGene$1$2
+.........1     .........0              jalview.ext.ensembl.EnsemblGene$1$1
+.........1     .........0              jalview.ext.ensembl.EnsemblGene$1
+.........1     .........0              jalview.ext.ensembl.EnsemblFeatures
+.........1     .........0              jalview.datamodel.features.SequenceFeatures$2
+.........1     .........0              jalview.datamodel.features.SequenceFeatures$1
+.........1     .........0              jalview.datamodel.features.FeatureAttributes.Datatype[]
+.........1     .........0              jalview.datamodel.Profiles
+.........1     .........0              jalview.datamodel.ProfileI[]
+.........1     .........0              jalview.analysis.CrossRef
+.........1     .........0              jalview.analysis.CodonComparator
+.........1     .........0              jalview.analysis.AnnotationSorter.SequenceAnnotationOrder[]
+.........1     ........-1              jalview.schemes.Consensus[]
+...5994529     ....111547      
\ No newline at end of file
diff --git a/optimization/timing-js-chrome-bh-3.txt b/optimization/timing-js-chrome-bh-3.txt
new file mode 100644 (file)
index 0000000..94f0b6f
--- /dev/null
@@ -0,0 +1,468 @@
+J2SApplet exec testApplet start applet null
+swingjs.api.Interface creating instance of javajs.util.AjaxURLStreamHandlerFactory
+get parameter: language = null
+get parameter: name = testApplet
+get parameter: syncId = 2491377188955504
+JSApp initialized
+JSAppletViewer initializing2
+JSToolkit initialized
+JSGraphicsConfiguration initialized
+swingjs.api.Interface creating instance of swingjs.JSGraphicsEnvironment
+JSGraphicsEnvironment initialized
+swingjs.api.Interface creating instance of swingjs.JSScreenDevice
+JSScreenDevice initialized
+JSAppletViewer thread run1 mode=0 status=0
+JSAppletViewer thread run1 mode=1 status=1
+JSAppletViewer runloader
+get parameter: main = jalview.bin.Jalview
+swingjs.api.Interface creating instance of swingjs.JSApplet
+swingjs.api.Interface creating instance of swingjs.plaf.HTML5LookAndFeel
+testApplet loaded
+JSAppletViewer thread run1 mode=1 status=76
+testApplet running jalview.bin.Jalview
+Running main(args) in class jalview.bin.Jalview
+Java version: 1.6-1.8
+null Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/71.0.3578.98 Safari/537.36 Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/71.0.3578.98 Safari/537.36
+JSUtil getting Java resource sun/util/resources/CalendarData.properties
+Processing swingjs/j2s/sun/util/resources/CalendarData.properties [1780]
+swingjs.api.Interface creating instance of java.util.PropertyResourceBundle
+JSUtil getting Java resource sun/util/resources/CalendarData_en.properties
+Processing swingjs/j2s/sun/util/resources/CalendarData_en.properties [1937]
+swingjs.api.Interface creating instance of sun.util.calendar.Gregorian
+swingjs.api.Interface creating instance of sun.text.resources.FormatData
+swingjs.api.Interface creating instance of sun.text.resources.FormatData_en
+Loading jalview properties from : https://./.jalview_properties
+Disabling Jalview writing to user's local properties file.
+Jalview Version: Test
+Jalview Debugging Output Follows.
+Getting messages for lang: en_US
+JSUtil getting Java resource lang/Messages.properties
+Processing swingjs/j2s/lang/Messages.properties [82729]
+JSUtil getting Java resource lang/Messages_en.properties
+Processing swingjs/j2s/lang/Messages_en.properties [5]
+JSUtil getting Java resource lang/Messages_en_US.properties
+Processing swingjs/j2s/lang/Messages_en_US.properties [5]
+JSUtil getting Java resource swingjs/jquery/j2sMenu.js
+Processing swingjs/j2s/swingjs/jquery/j2sMenu.js [27197]
+JSWIndowUI ????
+JSFrameViewer creating new canvas testApplet_canvas2: 900 613
+JSWindowUI windowOpened true
+JSFrameUI windowActivated true
+swingjs.api.Interface creating instance of swingjs.JSGraphicsConfiguration
+JSGraphicsConfiguration initialized
+JSPopupMenuUI processing 0 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 1 _hide for testApplet_PopupMenuUI_46_46
+noclickout 0 1548730342022
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+click added 0
+JSPopupMenuUI processing 2 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 3 onover3 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 4 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 5 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 6 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 7 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 8 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 9 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 10 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 11 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 12 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 13 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 14 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 15 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 16 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 17 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 18 onover3 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 19 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 20 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 21 onover3 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 22 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 23 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 24 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 25 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 26 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 27 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 28 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 29 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 30 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 31 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 32 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 33 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 34 onover3 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 35 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 36 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 37 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 38 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 39 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 40 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 41 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 42 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 43 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 44 onover3 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 45 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 46 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 47 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 48 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 49 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 50 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 51 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 52 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 53 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 54 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 55 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 56 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 57 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 58 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 59 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 60 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 61 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 62 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 63 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 64 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 65 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 66 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 67 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 68 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 69 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 70 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 71 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 72 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 73 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 74 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 75 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 76 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 77 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 78 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 79 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 80 onpress for testApplet_PopupMenuUI_46_46
+JSUtil getting Java resource swingjs/jquery/jquery-ui-j2sslider.css
+Processing swingjs/j2s/swingjs/jquery/jquery-ui-j2sslider.css [24188]
+JSUtil getting Java resource swingjs/jquery/jquery-ui-j2sslider.js
+Processing swingjs/j2s/swingjs/jquery/jquery-ui-j2sslider.js [22356]
+JSDesktopIconUI SURRAGATE -- NOT IMPLEMENTED YET!
+JSWIndowUI ????
+collapseAll 0
+JSPopupMenuUI processing 81 collapseAll for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 82 select for testApplet_PopupMenuUI_46_46
+collapseAll 0
+JSPopupMenuUI processing 83 collapseAll for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 84 onclick for testApplet_PopupMenuUI_46_46
+click removed 0
+JSFrameViewer creating new canvas testApplet_canvas3: 400 230
+JSWindowUI windowOpened true
+click removed 0
+JSFrameUI windowActivated true
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+Platform: timer mark    0.0    0.0    Desktop Fetching 1 sequence queries from ENSEMBL
+Platform: timer mark    0.708    0.676    EnsembleRestClient.getJSON https://rest.ensembl.org/lookup/id/ENSG00000157764?content-type=application/json
+Platform: timer mark    0.861    0.145    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    0.997    0.135    EnsembleRestClient.getJSON https://rest.ensembl.org/info/rest?content-type=application/json
+EnsemblRestClient expected ENSEMBL REST version 7.0 but found 9.0, see https://github.com/Ensembl/ensembl-rest/wiki/Change-log
+Platform: timer mark    1.151    0.136    EnsembleRestClient.getJSON https://rest.ensembl.org/info/data?content-type=application/json
+Platform: timer mark    1.153    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    1.153    0.0    ENS seqproxy
+Platform: timer mark    2.374    1.22    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENSG00000157764?type=genomic&Accept=application/json&content-type=application/json&object_type=Gene
+Platform: timer mark    2.468    0.094    ENS seqproxy2
+Platform: timer mark    2.564    0.096    ESP.getsequencerec1
+Platform: timer mark    14.377    11.8    EnsembleRestClient.getJSON https://rest.ensembl.org/overlap/id/ENSG00000157764?content-type=application/json&object_type=Gene&feature=gene&feature=transcript&feature=exon&feature=cds&feature=variation
+Platform: timer mark    19.553    5.176    ESP.getsequencerec2
+Platform: timer mark    19.579    0.026    ESP. xfer 46594
+Platform: timer mark    25.302    5.723    ESP.transferFeatures
+Platform: timer mark    25.302    0.0    ESP.addfeat done
+Platform: timer mark    25.303    0.001    ESP. getdataseq
+Platform: timer mark    25.303    0.0    ESP. getxref
+Platform: timer mark    26.69    1.382    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSG00000157764?content-type=application/json&all_levels=1
+Platform: timer mark    26.712    0.022    ESP. seqprox done
+Platform: timer mark    26.862    0.148    EnsembleRestClient.getJSON https://rest.ensembl.org/lookup/id/ENSG00000157764?content-type=application/json&object_type=Gene
+Platform: timer mark    27.648    0.786    ESP. getdataseq
+Platform: timer mark    27.65    0.002    ESP. getxref
+Platform: timer mark    28.252    0.602    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000646891?content-type=application/json&all_levels=1
+Platform: timer mark    28.257    0.005    ESP. seqprox done
+Adding protein product for ENST00000646891
+Platform: timer mark    28.541    0.279    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    28.541    0.0    EnsemblSeqProx.fetchSeq
+Platform: timer mark    28.542    0.001    ENS seqproxy
+Platform: timer mark    28.726    0.183    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000646891?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    28.727    0.001    ENS seqproxy2
+Platform: timer mark    28.728    0.001    ESP. getdataseq
+Platform: timer mark    28.729    0.001    ESP. getxref
+Platform: timer mark    29.058    0.327    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000493543?content-type=application/json&all_levels=1
+Platform: timer mark    29.061    0.003    ESP. seqprox done
+Platform: timer mark    29.742    0.681    ESP. getdataseq
+Platform: timer mark    29.742    0.0    ESP. getxref
+Platform: timer mark    30.018    0.275    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000496384?content-type=application/json&all_levels=1
+Platform: timer mark    30.019    0.001    ESP. seqprox done
+Adding protein product for ENST00000496384
+Platform: timer mark    30.02    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    30.02    0.0    ENS seqproxy
+Platform: timer mark    30.199    0.178    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000496384?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    30.2    0.001    ENS seqproxy2
+Platform: timer mark    30.201    0.001    ESP. getdataseq
+Platform: timer mark    30.201    0.0    ESP. getxref
+Platform: timer mark    30.362    0.16    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000419060?content-type=application/json&all_levels=1
+Platform: timer mark    30.364    0.002    ESP. seqprox done
+Platform: timer mark    30.807    0.443    ESP. getdataseq
+Platform: timer mark    30.808    0.001    ESP. getxref
+Platform: timer mark    30.982    0.174    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000469930?content-type=application/json&all_levels=1
+Platform: timer mark    30.983    0.001    ESP. seqprox done
+Adding protein product for ENST00000469930
+Platform: timer mark    30.984    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    30.985    0.001    ENS seqproxy
+Platform: timer mark    31.148    0.163    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000469930?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    31.149    0.001    ENS seqproxy2
+Platform: timer mark    31.149    0.0    ESP. getdataseq
+Platform: timer mark    31.15    0.001    ESP. getxref
+Platform: timer mark    31.297    0.146    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000495858?content-type=application/json&all_levels=1
+Platform: timer mark    31.299    0.002    ESP. seqprox done
+Platform: timer mark    31.777    0.478    ESP. getdataseq
+Platform: timer mark    31.777    0.0    ESP. getxref
+Platform: timer mark    31.959    0.181    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000288602?content-type=application/json&all_levels=1
+Platform: timer mark    31.961    0.002    ESP. seqprox done
+Adding protein product for ENST00000288602
+Platform: timer mark    31.961    0.0    EnsemblSeqProx.fetchSeq
+Platform: timer mark    31.962    0.001    ENS seqproxy
+Platform: timer mark    32.171    0.208    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000288602?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    32.173    0.002    ENS seqproxy2
+Platform: timer mark    32.173    0.0    ESP. getdataseq
+Platform: timer mark    32.175    0.002    ESP. getxref
+Platform: timer mark    32.324    0.149    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000288602?content-type=application/json&all_levels=1
+Platform: timer mark    32.326    0.002    ESP. seqprox done
+Platform: timer mark    32.775    0.449    ESP. getdataseq
+Platform: timer mark    32.775    0.0    ESP. getxref
+Platform: timer mark    32.929    0.152    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000642272?content-type=application/json&all_levels=1
+Platform: timer mark    32.93    0.001    ESP. seqprox done
+Adding protein product for ENST00000642272
+Platform: timer mark    32.932    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    32.932    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    33.086    0.153    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000642272?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000642272
+Platform: timer mark    33.48    0.394    ESP. getdataseq
+Platform: timer mark    33.481    0.001    ESP. getxref
+Platform: timer mark    33.883    0.402    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000643790?content-type=application/json&all_levels=1
+Platform: timer mark    33.884    0.001    ESP. seqprox done
+Adding protein product for ENST00000643790
+Platform: timer mark    33.885    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    33.885    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    34.069    0.183    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000643790?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000643790
+Platform: timer mark    34.476    0.407    ESP. getdataseq
+Platform: timer mark    34.478    0.002    ESP. getxref
+Platform: timer mark    34.866    0.388    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000646427?content-type=application/json&all_levels=1
+Platform: timer mark    34.867    0.001    ESP. seqprox done
+Adding protein product for ENST00000646427
+Platform: timer mark    34.869    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    34.869    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    35.056    0.186    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000646427?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000646427
+Platform: timer mark    35.448    0.392    ESP. getdataseq
+Platform: timer mark    35.449    0.001    ESP. getxref
+Platform: timer mark    35.836    0.386    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000642808?content-type=application/json&all_levels=1
+Platform: timer mark    35.836    0.0    ESP. seqprox done
+Adding protein product for ENST00000642808
+Platform: timer mark    35.838    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    35.838    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    35.986    0.147    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000642808?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000642808
+Platform: timer mark    36.376    0.39    ESP. getdataseq
+Platform: timer mark    36.377    0.001    ESP. getxref
+Platform: timer mark    36.76    0.383    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000643356?content-type=application/json&all_levels=1
+Platform: timer mark    36.761    0.001    ESP. seqprox done
+Adding protein product for ENST00000643356
+Platform: timer mark    36.762    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    36.763    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    36.931    0.167    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000643356?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000643356
+Platform: timer mark    37.389    0.458    ESP. getdataseq
+Platform: timer mark    37.39    0.001    ESP. getxref
+Platform: timer mark    37.783    0.393    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000497784?content-type=application/json&all_levels=1
+Platform: timer mark    37.785    0.002    ESP. seqprox done
+Adding protein product for ENST00000497784
+Platform: timer mark    37.786    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    37.787    0.001    ENS seqproxy
+Platform: timer mark    37.963    0.175    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000497784?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    37.965    0.002    ENS seqproxy2
+Platform: timer mark    37.966    0.001    ESP. getdataseq
+Platform: timer mark    37.966    0.0    ESP. getxref
+Platform: timer mark    38.133    0.166    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000420119?content-type=application/json&all_levels=1
+Platform: timer mark    38.134    0.001    ESP. seqprox done
+Platform: timer mark    38.548    0.414    ESP. getdataseq
+Platform: timer mark    38.549    0.001    ESP. getxref
+Platform: timer mark    38.688    0.138    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000646334?content-type=application/json&all_levels=1
+Platform: timer mark    38.689    0.001    ESP. seqprox done
+Adding protein product for ENST00000646334
+Platform: timer mark    38.829    0.139    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    38.83    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    38.831    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    39.007    0.175    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000646334?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000646334
+Platform: timer mark    39.468    0.461    ESP. getdataseq
+Platform: timer mark    39.469    0.001    ESP. getxref
+Platform: timer mark    39.876    0.406    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000646730?content-type=application/json&all_levels=1
+Platform: timer mark    39.877    0.001    ESP. seqprox done
+Adding protein product for ENST00000646730
+Platform: timer mark    39.878    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    39.879    0.001    ENS seqproxy
+Platform: timer mark    40.062    0.182    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000646730?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    40.063    0.001    ENS seqproxy2
+Platform: timer mark    40.064    0.001    ESP. getdataseq
+Platform: timer mark    40.065    0.001    ESP. getxref
+Platform: timer mark    40.233    0.167    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000494784?content-type=application/json&all_levels=1
+Platform: timer mark    40.234    0.001    ESP. seqprox done
+Platform: timer mark    40.685    0.451    ESP. getdataseq
+Platform: timer mark    40.686    0.001    ESP. getxref
+Platform: timer mark    40.861    0.174    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000644650?content-type=application/json&all_levels=1
+Platform: timer mark    40.862    0.001    ESP. seqprox done
+Adding protein product for ENST00000644650
+Platform: timer mark    40.864    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    40.865    0.001    ENS seqproxy
+Platform: timer mark    41.022    0.156    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000644650?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    41.024    0.002    ENS seqproxy2
+Platform: timer mark    41.025    0.001    ESP. getdataseq
+Platform: timer mark    41.025    0.0    ESP. getxref
+Platform: timer mark    41.288    0.262    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000493783?content-type=application/json&all_levels=1
+Platform: timer mark    41.29    0.002    ESP. seqprox done
+Error retrieving protein for ENST00000644650: Index: -1, Size: 1
+Platform: timer mark    41.854    0.564    ESP. getdataseq
+Platform: timer mark    41.855    0.001    ESP. getxref
+Platform: timer mark    42.028    0.172    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000647434?content-type=application/json&all_levels=1
+Platform: timer mark    42.03    0.002    ESP. seqprox done
+Adding protein product for ENST00000647434
+Platform: timer mark    42.032    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    42.033    0.001    ENS seqproxy
+Platform: timer mark    42.214    0.18    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000647434?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    42.215    0.001    ENS seqproxy2
+Platform: timer mark    42.216    0.001    ESP. getdataseq
+Platform: timer mark    42.218    0.002    ESP. getxref
+Platform: timer mark    42.386    0.168    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000495132?content-type=application/json&all_levels=1
+Platform: timer mark    42.387    0.001    ESP. seqprox done
+Platform: timer mark    43.127    0.74    ESP. getdataseq
+Platform: timer mark    43.128    0.001    ESP. getxref
+Platform: timer mark    43.301    0.172    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000479537?content-type=application/json&all_levels=1
+Platform: timer mark    43.302    0.001    ESP. seqprox done
+Adding protein product for ENST00000479537
+Platform: timer mark    43.305    0.003    EnsemblSeqProx.fetchSeq
+Platform: timer mark    43.305    0.0    ENS seqproxy
+Platform: timer mark    43.517    0.211    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000479537?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    43.518    0.001    ENS seqproxy2
+Platform: timer mark    43.52    0.002    ESP. getdataseq
+Platform: timer mark    43.521    0.001    ESP. getxref
+Platform: timer mark    43.682    0.161    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000418033?content-type=application/json&all_levels=1
+Platform: timer mark    43.683    0.001    ESP. seqprox done
+Error retrieving protein for ENST00000479537: Index: -1, Size: 1
+Platform: timer mark    44.125    0.442    ESP. getdataseq
+Platform: timer mark    44.126    0.001    ESP. getxref
+Platform: timer mark    44.274    0.147    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000645443?content-type=application/json&all_levels=1
+Platform: timer mark    44.276    0.002    ESP. seqprox done
+Adding protein product for ENST00000645443
+Platform: timer mark    44.277    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    44.278    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    44.425    0.146    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000645443?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000645443
+Platform: timer mark    44.955    0.53    ESP. getdataseq
+Platform: timer mark    44.955    0.0    ESP. getxref
+Platform: timer mark    45.389    0.432    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000644905?content-type=application/json&all_levels=1
+Platform: timer mark    45.39    0.001    ESP. seqprox done
+Adding protein product for ENST00000644905
+Platform: timer mark    45.393    0.003    EnsemblSeqProx.fetchSeq
+Platform: timer mark    45.393    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    45.541    0.146    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000644905?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000644905
+Platform: timer mark    46.111    0.57    ESP. getdataseq
+Platform: timer mark    46.112    0.001    ESP. getxref
+Platform: timer mark    46.535    0.422    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000642228?content-type=application/json&all_levels=1
+Platform: timer mark    46.537    0.002    ESP. seqprox done
+Adding protein product for ENST00000642228
+Platform: timer mark    46.539    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    46.54    0.001    ENS seqproxy
+Platform: timer mark    46.708    0.168    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000642228?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    46.71    0.002    ENS seqproxy2
+Platform: timer mark    46.711    0.001    ESP. getdataseq
+Platform: timer mark    46.712    0.001    ESP. getxref
+Platform: timer mark    46.883    0.171    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000493678?content-type=application/json&all_levels=1
+Platform: timer mark    46.884    0.001    ESP. seqprox done
+Platform: timer mark    47.421    0.537    ESP. getdataseq
+Platform: timer mark    47.421    0.0    ESP. getxref
+Platform: timer mark    47.599    0.176    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000644969?content-type=application/json&all_levels=1
+Platform: timer mark    47.6    0.001    ESP. seqprox done
+Adding protein product for ENST00000644969
+Platform: timer mark    47.602    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    47.603    0.001    ENS seqproxy
+Platform: timer mark    47.781    0.176    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000644969?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    47.782    0.001    ENS seqproxy2
+Platform: timer mark    47.785    0.003    ESP. getdataseq
+Platform: timer mark    47.786    0.001    ESP. getxref
+Platform: timer mark    47.94    0.154    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000496776?content-type=application/json&all_levels=1
+Platform: timer mark    47.941    0.001    ESP. seqprox done
+Platform: timer mark    48.435    0.494    ESP. getdataseq
+Platform: timer mark    48.436    0.001    ESP. getxref
+Platform: timer mark    48.577    0.14    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000644120?content-type=application/json&all_levels=1
+Platform: timer mark    48.579    0.002    ESP. seqprox done
+Adding protein product for ENST00000644120
+Platform: timer mark    48.58    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    48.581    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    48.755    0.173    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000644120?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000644120
+Platform: timer mark    49.205    0.45    ESP. getdataseq
+Platform: timer mark    49.206    0.001    ESP. getxref
+Platform: timer mark    49.588    0.38    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000642875?content-type=application/json&all_levels=1
+Platform: timer mark    49.589    0.001    ESP. seqprox done
+Adding protein product for ENST00000642875
+Platform: timer mark    49.74    0.149    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    49.741    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    49.742    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    49.894    0.15    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000642875?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000642875
+Platform: timer mark    50.194    0.3    Desktop Finished querying
+Platform: timer mark    50.199    0.005    Desktop Parsing results.
+JSDesktopIconUI SURRAGATE -- NOT IMPLEMENTED YET!
+JSWIndowUI ????
+Platform: timer mark    63.835    13.636    Desktop null
+JSFrameViewer creating new canvas testApplet_canvas4: 700 465
+JSWindowUI windowOpened true
+JSFrameUI windowActivated true
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+JSWIndowUI ????
+JSFrameViewer creating new canvas testApplet_canvas5: 173 18
+JSWIndowUI ????
+JSFrameViewer creating new canvas testApplet_canvas6: 138 18
+This is System.out. clear it 
+Add ?j2snocore to URL to see full class list; ?j2sdebug to use uncompressed j2s/core files 
+get _j2sClassList.txt Jalview TestX
+New Sequence FetcherX
+ExampleClearOKCancel
+
+ENSG00000157764
+Example query: ENSG00000157764
+Enter one or more accession IDs separated by a semi-colon ";"
+Replace commas with semi-colons
+Retrieved from ENSEMBLX
+Sequence 1 ID: ENSG00000157764 Nucleotide: Cytosine (32)
+File
+Edit
+Select
+View
+Annotations
+Format
+Colour
+Calculate
+File
+Tools
+Help
+Window
\ No newline at end of file
diff --git a/optimization/timing-js-firefox-bh-3.txt b/optimization/timing-js-firefox-bh-3.txt
new file mode 100644 (file)
index 0000000..5bb13b6
--- /dev/null
@@ -0,0 +1,442 @@
+firefox back to Java's StringBuilder - 100 sec
+J2SApplet exec testApplet start applet null
+swingjs.api.Interface creating instance of javajs.util.AjaxURLStreamHandlerFactory
+get parameter: language = null
+get parameter: name = testApplet
+get parameter: syncId = 30614127558744375
+JSApp initialized
+JSAppletViewer initializing2
+JSToolkit initialized
+JSGraphicsConfiguration initialized
+swingjs.api.Interface creating instance of swingjs.JSGraphicsEnvironment
+JSGraphicsEnvironment initialized
+swingjs.api.Interface creating instance of swingjs.JSScreenDevice
+JSScreenDevice initialized
+JSAppletViewer thread run1 mode=0 status=0
+JSAppletViewer thread run1 mode=1 status=1
+JSAppletViewer runloader
+get parameter: main = jalview.bin.Jalview
+swingjs.api.Interface creating instance of swingjs.JSApplet
+swingjs.api.Interface creating instance of swingjs.plaf.HTML5LookAndFeel
+testApplet loaded
+JSAppletViewer thread run1 mode=1 status=76
+testApplet running jalview.bin.Jalview
+Running main(args) in class jalview.bin.Jalview
+Java version: 1.6-1.8
+null Mozilla/5.0 (Windows NT 10.0; Win64; x64; rv:64.0) Gecko/20100101 Firefox/64.0 Mozilla/5.0 (Windows NT 10.0; Win64; x64; rv:64.0) Gecko/20100101 Firefox/64.0
+JSUtil getting Java resource sun/util/resources/CalendarData.properties
+Processing swingjs/j2s/sun/util/resources/CalendarData.properties [1780]
+swingjs.api.Interface creating instance of java.util.PropertyResourceBundle
+JSUtil getting Java resource sun/util/resources/CalendarData_en.properties
+Processing swingjs/j2s/sun/util/resources/CalendarData_en.properties [1937]
+swingjs.api.Interface creating instance of sun.util.calendar.Gregorian
+swingjs.api.Interface creating instance of sun.text.resources.FormatData
+swingjs.api.Interface creating instance of sun.text.resources.FormatData_en
+Loading jalview properties from : https://./.jalview_properties
+Disabling Jalview writing to user's local properties file.
+Jalview Version: Test
+Jalview Debugging Output Follows.
+Getting messages for lang: en_US
+JSUtil getting Java resource lang/Messages.properties
+Processing swingjs/j2s/lang/Messages.properties [82729]
+JSUtil getting Java resource lang/Messages_en.properties
+Processing swingjs/j2s/lang/Messages_en.properties [39]
+JSUtil getting Java resource lang/Messages_en_US.properties
+Processing swingjs/j2s/lang/Messages_en_US.properties [39]
+JSUtil getting Java resource swingjs/jquery/j2sMenu.js
+Processing swingjs/j2s/swingjs/jquery/j2sMenu.js [27197]
+JSWIndowUI ????
+JSFrameViewer creating new canvas testApplet_canvas2: 900 613
+JSWindowUI windowOpened true
+JSFrameUI windowActivated true
+swingjs.api.Interface creating instance of swingjs.JSGraphicsConfiguration
+JSGraphicsConfiguration initialized
+JSPopupMenuUI processing 0 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 1 _hide for testApplet_PopupMenuUI_46_46
+noclickout 0 1548730538973
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+click added 0
+JSPopupMenuUI processing 2 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 3 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 4 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 5 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 6 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 7 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 8 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 9 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 10 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 11 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 12 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 13 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 14 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 15 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 16 onover3 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 17 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 18 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 19 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 20 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 21 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 22 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 23 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 24 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 25 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 26 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 27 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 28 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 29 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 30 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 31 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 32 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 33 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 34 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 35 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 36 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 37 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 38 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 39 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 40 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 41 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 42 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 43 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 44 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 45 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 46 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 47 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 48 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 49 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 50 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 51 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 52 _hide for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 53 _closeSubmenus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 54 blur for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 55 focus for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 56 onover1 for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 57 onpress for testApplet_PopupMenuUI_46_46
+JSUtil getting Java resource swingjs/jquery/jquery-ui-j2sslider.css
+Processing swingjs/j2s/swingjs/jquery/jquery-ui-j2sslider.css [24188]
+JSUtil getting Java resource swingjs/jquery/jquery-ui-j2sslider.js
+Processing swingjs/j2s/swingjs/jquery/jquery-ui-j2sslider.js [22356]
+JSDesktopIconUI SURRAGATE -- NOT IMPLEMENTED YET!
+JSWIndowUI ????
+collapseAll 0
+JSPopupMenuUI processing 58 collapseAll for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 59 select for testApplet_PopupMenuUI_46_46
+collapseAll 0
+JSPopupMenuUI processing 60 collapseAll for testApplet_PopupMenuUI_46_46
+JSPopupMenuUI processing 61 onclick for testApplet_PopupMenuUI_46_46
+click removed 0
+JSFrameViewer creating new canvas testApplet_canvas3: 400 230
+JSWindowUI windowOpened true
+click removed 0
+JSFrameUI windowActivated true
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+PostEventQueue posting tempEvent java.awt.SentEvent[] on [swingjs.JSToolkit object]
+Platform: timer mark    0.0    0.0    Desktop Fetching 1 sequence queries from ENSEMBL
+Platform: timer mark    0.491    0.432    EnsembleRestClient.getJSON https://rest.ensembl.org/lookup/id/ENSG00000157764?content-type=application/json
+Platform: timer mark    0.655    0.157    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    0.816    0.159    EnsembleRestClient.getJSON https://rest.ensembl.org/info/rest?content-type=application/json
+EnsemblRestClient expected ENSEMBL REST version 7.0 but found 9.0, see https://github.com/Ensembl/ensembl-rest/wiki/Change-log
+Platform: timer mark    0.967    0.134    EnsembleRestClient.getJSON https://rest.ensembl.org/info/data?content-type=application/json
+Platform: timer mark    0.968    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    0.969    0.001    ENS seqproxy
+Platform: timer mark    1.946    0.975    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENSG00000157764?type=genomic&Accept=application/json&content-type=application/json&object_type=Gene
+Platform: timer mark    1.994    0.048    ENS seqproxy2
+Platform: timer mark    2.173    0.179    ESP.getsequencerec1
+Platform: timer mark    13.687    11.512    EnsembleRestClient.getJSON https://rest.ensembl.org/overlap/id/ENSG00000157764?content-type=application/json&object_type=Gene&feature=gene&feature=transcript&feature=exon&feature=cds&feature=variation
+Platform: timer mark    26.028    12.341    ESP.getsequencerec2
+Platform: timer mark    26.069    0.041    ESP. xfer 46594
+Platform: timer mark    43.878    17.809    ESP.transferFeatures
+Platform: timer mark    43.878    0.0    ESP.addfeat done
+Platform: timer mark    43.879    0.001    ESP. getdataseq
+Platform: timer mark    43.88    0.001    ESP. getxref
+Platform: timer mark    45.354    1.467    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSG00000157764?content-type=application/json&all_levels=1
+Platform: timer mark    45.388    0.034    ESP. seqprox done
+Platform: timer mark    45.556    0.166    EnsembleRestClient.getJSON https://rest.ensembl.org/lookup/id/ENSG00000157764?content-type=application/json&object_type=Gene
+Platform: timer mark    47.029    1.473    ESP. getdataseq
+Platform: timer mark    47.029    0.0    ESP. getxref
+Platform: timer mark    47.63    0.599    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000646891?content-type=application/json&all_levels=1
+Platform: timer mark    47.642    0.012    ESP. seqprox done
+Adding protein product for ENST00000646891
+Platform: timer mark    47.822    0.171    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    47.823    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    47.823    0.0    ENS seqproxy
+Platform: timer mark    47.998    0.174    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000646891?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    48.0    0.002    ENS seqproxy2
+Platform: timer mark    48.002    0.002    ESP. getdataseq
+Platform: timer mark    48.002    0.0    ESP. getxref
+Platform: timer mark    48.383    0.38    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000493543?content-type=application/json&all_levels=1
+Platform: timer mark    48.39    0.007    ESP. seqprox done
+Platform: timer mark    50.109    1.719    ESP. getdataseq
+Platform: timer mark    50.11    0.001    ESP. getxref
+Platform: timer mark    50.324    0.213    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000496384?content-type=application/json&all_levels=1
+Platform: timer mark    50.326    0.002    ESP. seqprox done
+Adding protein product for ENST00000496384
+Platform: timer mark    50.328    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    50.328    0.0    ENS seqproxy
+Platform: timer mark    50.599    0.271    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000496384?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    50.6    0.001    ENS seqproxy2
+Platform: timer mark    50.603    0.003    ESP. getdataseq
+Platform: timer mark    50.603    0.0    ESP. getxref
+Platform: timer mark    50.779    0.174    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000419060?content-type=application/json&all_levels=1
+Platform: timer mark    50.78    0.001    ESP. seqprox done
+Platform: timer mark    51.955    1.175    ESP. getdataseq
+Platform: timer mark    51.956    0.001    ESP. getxref
+Platform: timer mark    52.112    0.156    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000469930?content-type=application/json&all_levels=1
+Platform: timer mark    52.114    0.002    ESP. seqprox done
+Adding protein product for ENST00000469930
+Platform: timer mark    52.114    0.0    EnsemblSeqProx.fetchSeq
+Platform: timer mark    52.115    0.001    ENS seqproxy
+Platform: timer mark    52.286    0.17    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000469930?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    52.287    0.001    ENS seqproxy2
+Platform: timer mark    52.288    0.001    ESP. getdataseq
+Platform: timer mark    52.29    0.002    ESP. getxref
+Platform: timer mark    52.443    0.153    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000495858?content-type=application/json&all_levels=1
+Platform: timer mark    52.444    0.001    ESP. seqprox done
+Platform: timer mark    53.65    1.206    ESP. getdataseq
+Platform: timer mark    53.651    0.001    ESP. getxref
+Platform: timer mark    53.827    0.175    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000288602?content-type=application/json&all_levels=1
+Platform: timer mark    53.828    0.001    ESP. seqprox done
+Adding protein product for ENST00000288602
+Platform: timer mark    53.829    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    53.829    0.0    ENS seqproxy
+Platform: timer mark    54.0    0.17    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000288602?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    54.001    0.001    ENS seqproxy2
+Platform: timer mark    54.003    0.002    ESP. getdataseq
+Platform: timer mark    54.003    0.0    ESP. getxref
+Platform: timer mark    54.163    0.159    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000288602?content-type=application/json&all_levels=1
+Platform: timer mark    54.165    0.002    ESP. seqprox done
+Platform: timer mark    55.476    1.311    ESP. getdataseq
+Platform: timer mark    55.476    0.0    ESP. getxref
+Platform: timer mark    55.624    0.146    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000642272?content-type=application/json&all_levels=1
+Platform: timer mark    55.625    0.001    ESP. seqprox done
+Adding protein product for ENST00000642272
+Platform: timer mark    55.626    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    55.627    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    55.783    0.156    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000642272?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000642272
+Platform: timer mark    56.888    1.105    ESP. getdataseq
+Platform: timer mark    56.888    0.0    ESP. getxref
+Platform: timer mark    57.272    0.383    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000643790?content-type=application/json&all_levels=1
+Platform: timer mark    57.273    0.001    ESP. seqprox done
+Adding protein product for ENST00000643790
+Platform: timer mark    57.274    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    57.275    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    57.492    0.217    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000643790?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000643790
+Platform: timer mark    58.611    1.119    ESP. getdataseq
+Platform: timer mark    58.611    0.0    ESP. getxref
+Platform: timer mark    59.016    0.404    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000646427?content-type=application/json&all_levels=1
+Platform: timer mark    59.017    0.001    ESP. seqprox done
+Adding protein product for ENST00000646427
+Platform: timer mark    59.163    0.145    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    59.164    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    59.164    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    59.313    0.149    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000646427?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000646427
+Platform: timer mark    60.364    1.051    ESP. getdataseq
+Platform: timer mark    60.364    0.0    ESP. getxref
+Platform: timer mark    60.773    0.408    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000642808?content-type=application/json&all_levels=1
+Platform: timer mark    60.774    0.001    ESP. seqprox done
+Adding protein product for ENST00000642808
+Platform: timer mark    60.775    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    60.775    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    60.925    0.149    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000642808?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000642808
+Platform: timer mark    61.993    1.068    ESP. getdataseq
+Platform: timer mark    61.993    0.0    ESP. getxref
+Platform: timer mark    62.389    0.394    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000643356?content-type=application/json&all_levels=1
+Platform: timer mark    62.39    0.001    ESP. seqprox done
+Adding protein product for ENST00000643356
+Platform: timer mark    62.392    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    62.392    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    62.569    0.176    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000643356?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000643356
+Platform: timer mark    63.782    1.213    ESP. getdataseq
+Platform: timer mark    63.782    0.0    ESP. getxref
+Platform: timer mark    64.172    0.389    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000497784?content-type=application/json&all_levels=1
+Platform: timer mark    64.173    0.001    ESP. seqprox done
+Adding protein product for ENST00000497784
+Platform: timer mark    64.175    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    64.176    0.001    ENS seqproxy
+Platform: timer mark    64.375    0.199    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000497784?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    64.376    0.001    ENS seqproxy2
+Platform: timer mark    64.378    0.002    ESP. getdataseq
+Platform: timer mark    64.379    0.001    ESP. getxref
+Platform: timer mark    64.606    0.227    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000420119?content-type=application/json&all_levels=1
+Platform: timer mark    64.607    0.001    ESP. seqprox done
+Platform: timer mark    65.783    1.176    ESP. getdataseq
+Platform: timer mark    65.784    0.001    ESP. getxref
+Platform: timer mark    65.932    0.147    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000646334?content-type=application/json&all_levels=1
+Platform: timer mark    65.933    0.001    ESP. seqprox done
+Adding protein product for ENST00000646334
+Platform: timer mark    65.934    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    65.935    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    66.087    0.152    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000646334?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000646334
+Platform: timer mark    67.322    1.235    ESP. getdataseq
+Platform: timer mark    67.323    0.001    ESP. getxref
+Platform: timer mark    67.738    0.415    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000646730?content-type=application/json&all_levels=1
+Platform: timer mark    67.74    0.002    ESP. seqprox done
+Adding protein product for ENST00000646730
+Platform: timer mark    67.741    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    67.741    0.0    ENS seqproxy
+Platform: timer mark    67.915    0.173    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000646730?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    67.915    0.0    ENS seqproxy2
+Platform: timer mark    67.917    0.002    ESP. getdataseq
+Platform: timer mark    67.917    0.0    ESP. getxref
+Platform: timer mark    68.073    0.155    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000494784?content-type=application/json&all_levels=1
+Platform: timer mark    68.074    0.001    ESP. seqprox done
+Platform: timer mark    69.304    1.23    ESP. getdataseq
+Platform: timer mark    69.305    0.001    ESP. getxref
+Platform: timer mark    69.478    0.173    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000644650?content-type=application/json&all_levels=1
+Platform: timer mark    69.479    0.001    ESP. seqprox done
+Adding protein product for ENST00000644650
+Platform: timer mark    69.628    0.148    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    69.628    0.0    EnsemblSeqProx.fetchSeq
+Platform: timer mark    69.629    0.001    ENS seqproxy
+Platform: timer mark    69.825    0.196    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000644650?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    69.826    0.001    ENS seqproxy2
+Platform: timer mark    69.827    0.001    ESP. getdataseq
+Platform: timer mark    69.828    0.001    ESP. getxref
+Platform: timer mark    69.974    0.145    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000493783?content-type=application/json&all_levels=1
+Platform: timer mark    69.976    0.002    ESP. seqprox done
+Error retrieving protein for ENST00000644650: Index: -1, Size: 1
+Platform: timer mark    71.231    1.255    ESP. getdataseq
+Platform: timer mark    71.233    0.002    ESP. getxref
+Platform: timer mark    71.398    0.165    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000647434?content-type=application/json&all_levels=1
+Platform: timer mark    71.4    0.002    ESP. seqprox done
+Adding protein product for ENST00000647434
+Platform: timer mark    71.4    0.0    EnsemblSeqProx.fetchSeq
+Platform: timer mark    71.402    0.002    ENS seqproxy
+Platform: timer mark    71.581    0.179    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000647434?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    71.582    0.001    ENS seqproxy2
+Platform: timer mark    71.584    0.002    ESP. getdataseq
+Platform: timer mark    71.585    0.001    ESP. getxref
+Platform: timer mark    71.745    0.159    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000495132?content-type=application/json&all_levels=1
+Platform: timer mark    71.747    0.002    ESP. seqprox done
+Platform: timer mark    73.744    1.997    ESP. getdataseq
+Platform: timer mark    73.744    0.0    ESP. getxref
+Platform: timer mark    73.91    0.164    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000479537?content-type=application/json&all_levels=1
+Platform: timer mark    73.911    0.001    ESP. seqprox done
+Adding protein product for ENST00000479537
+Platform: timer mark    73.912    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    73.912    0.0    ENS seqproxy
+Platform: timer mark    74.088    0.175    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000479537?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    74.09    0.002    ENS seqproxy2
+Platform: timer mark    74.091    0.001    ESP. getdataseq
+Platform: timer mark    74.092    0.001    ESP. getxref
+Platform: timer mark    74.24    0.148    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000418033?content-type=application/json&all_levels=1
+Platform: timer mark    74.241    0.001    ESP. seqprox done
+Error retrieving protein for ENST00000479537: Index: -1, Size: 1
+Platform: timer mark    75.433    1.192    ESP. getdataseq
+Platform: timer mark    75.433    0.0    ESP. getxref
+Platform: timer mark    75.603    0.169    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000645443?content-type=application/json&all_levels=1
+Platform: timer mark    75.604    0.001    ESP. seqprox done
+Adding protein product for ENST00000645443
+Platform: timer mark    75.606    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    75.606    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    75.753    0.147    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000645443?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000645443
+Platform: timer mark    77.126    1.373    ESP. getdataseq
+Platform: timer mark    77.126    0.0    ESP. getxref
+Platform: timer mark    77.538    0.412    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000644905?content-type=application/json&all_levels=1
+Platform: timer mark    77.54    0.002    ESP. seqprox done
+Adding protein product for ENST00000644905
+Platform: timer mark    77.54    0.0    EnsemblSeqProx.fetchSeq
+Platform: timer mark    77.541    0.001    ENS seqproxy
+Response code 400
+Platform: timer mark    77.708    0.166    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000644905?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000644905
+Platform: timer mark    78.958    1.25    ESP. getdataseq
+Platform: timer mark    78.958    0.0    ESP. getxref
+Platform: timer mark    79.409    0.45    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000642228?content-type=application/json&all_levels=1
+Platform: timer mark    79.411    0.002    ESP. seqprox done
+Adding protein product for ENST00000642228
+Platform: timer mark    79.412    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    79.412    0.0    ENS seqproxy
+Platform: timer mark    79.571    0.159    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000642228?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    79.573    0.002    ENS seqproxy2
+Platform: timer mark    79.574    0.001    ESP. getdataseq
+Platform: timer mark    79.574    0.0    ESP. getxref
+Platform: timer mark    79.736    0.161    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000493678?content-type=application/json&all_levels=1
+Platform: timer mark    79.737    0.001    ESP. seqprox done
+Platform: timer mark    81.189    1.452    ESP. getdataseq
+Platform: timer mark    81.19    0.001    ESP. getxref
+Platform: timer mark    81.389    0.198    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000644969?content-type=application/json&all_levels=1
+Platform: timer mark    81.391    0.002    ESP. seqprox done
+Adding protein product for ENST00000644969
+Platform: timer mark    81.563    0.171    EnsembleRestClient.getJSON https://rest.ensembl.org/info/ping?content-type=application/json
+Platform: timer mark    81.564    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    81.565    0.001    ENS seqproxy
+Platform: timer mark    81.739    0.174    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000644969?type=protein&Accept=application/json&content-type=application/json
+Platform: timer mark    81.739    0.0    ENS seqproxy2
+Platform: timer mark    81.741    0.002    ESP. getdataseq
+Platform: timer mark    81.741    0.0    ESP. getxref
+Platform: timer mark    81.905    0.162    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENSP00000496776?content-type=application/json&all_levels=1
+Platform: timer mark    81.907    0.002    ESP. seqprox done
+Platform: timer mark    83.297    1.39    ESP. getdataseq
+Platform: timer mark    83.297    0.0    ESP. getxref
+Platform: timer mark    83.441    0.143    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000644120?content-type=application/json&all_levels=1
+Platform: timer mark    83.442    0.001    ESP. seqprox done
+Adding protein product for ENST00000644120
+Platform: timer mark    83.444    0.002    EnsemblSeqProx.fetchSeq
+Platform: timer mark    83.444    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    83.601    0.156    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000644120?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000644120
+Platform: timer mark    84.848    1.247    ESP. getdataseq
+Platform: timer mark    84.849    0.001    ESP. getxref
+Platform: timer mark    85.248    0.398    EnsembleRestClient.getJSON https://rest.ensembl.org/xrefs/id/ENST00000642875?content-type=application/json&all_levels=1
+Platform: timer mark    85.249    0.001    ESP. seqprox done
+Adding protein product for ENST00000642875
+Platform: timer mark    85.25    0.001    EnsemblSeqProx.fetchSeq
+Platform: timer mark    85.25    0.0    ENS seqproxy
+Response code 400
+Platform: timer mark    85.401    0.15    EnsembleRestClient.getJSON https://rest.ensembl.org/sequence/id/ENST00000642875?type=protein&Accept=application/json&content-type=application/json
+No protein product found for ENST00000642875
+Platform: timer mark    86.467    1.066    Desktop Finished querying
+Platform: timer mark    86.479    0.012    Desktop Parsing results.
+JSDesktopIconUI SURRAGATE -- NOT IMPLEMENTED YET!
+JSWIndowUI ????
+Platform: timer mark    100.466    13.987    Desktop null
+JSFrameViewer creating new canvas testApplet_canvas4: 700 465
+JSWindowUI windowOpened true
+swingjs.api.Interface creating instance of java.awt.datatransfer.Clipboard
+This is System.out. clear it
+Add ?j2snocore to URL to see full class list; ?j2sdebug to use uncompressed j2s/core files
+get _j2sClassList.txt
+Jalview Test
+X
+Retrieved from ENSEMBL
+X
+Copied 22 sequences to clipboard.
+File
+Edit
+Select
+View
+Annotations
+Format
+Colour
+Calculate
+New Sequence Fetcher
+X
+ENSG00000157764
+Example query: ENSG00000157764
+Enter one or more accession IDs separated by a semi-colon ";"
+Replace commas with semi-colons
+File
+Tools
+Help
+Window
\ No newline at end of file
index 93ad332..300c950 100755 (executable)
@@ -195,6 +195,7 @@ public class Alignment implements AlignmentI
   {
     synchronized (sequences)
     {
+    
       if (i > -1 && i < sequences.size())
       {
         return sequences.get(i);
@@ -589,11 +590,12 @@ public class Alignment implements AlignmentI
     int i = 0;
     SequenceI sq = null;
     String sqname = null;
+    int nseq = sequences.size();
     if (startAfter != null)
     {
       // try to find the sequence in the alignment
       boolean matched = false;
-      while (i < sequences.size())
+      while (i < nseq)
       {
         if (getSequenceAt(i++) == startAfter)
         {
@@ -606,7 +608,7 @@ public class Alignment implements AlignmentI
         i = 0;
       }
     }
-    while (i < sequences.size())
+    while (i < nseq)
     {
       sq = getSequenceAt(i);
       sqname = sq.getName();
index da9d2e5..bef1db0 100644 (file)
@@ -501,17 +501,17 @@ boolean checkEnsembl()
        if (url == null)
           url = getUrl(ids);
        
-//     Platform.timeCheck("EnsembleRestClient.getJSON0 " + url, Platform.TIME_MARK);
-       
        Reader br = null;
        try {
+
+         Platform.timeCheck(null, Platform.TIME_MARK);
+               
       br = (url == null ? null : getHttpResponse(url, ids, msDelay));
 
-//      Platform.timeCheck("EnsembleRestClient.getJSON1 parsing... ", Platform.TIME_MARK);
-       
       Object ret = (br == null ? null : JSONUtils.parse(br));
 
-//      Platform.timeCheck("EnsembleRestClient.getJSON2 ...done ", Platform.TIME_MARK);
+         Platform.timeCheck("EnsembleRestClient.getJSON " + url, Platform.TIME_MARK);
+       
 
       if (ret != null && mapKey != null)
            ret = ((Map<String, Object>) ret).get(mapKey);
index a558ad2..2e20665 100644 (file)
@@ -171,14 +171,15 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
      * fetch and transfer genomic sequence features,
      * fetch protein product and add as cross-reference
      */
-    for (String accId : allIds)
+    for (int i = 0, n = allIds.size(); i < n; i++) 
     {
-      addFeaturesAndProduct(accId, alignment);
+      addFeaturesAndProduct(allIds.get(i), alignment);
     }
 
-    for (SequenceI seq : alignment.getSequences())
+    List<SequenceI> seqs = alignment.getSequences();
+    for (int i = 0, n = seqs.size(); i < n; i++)
     {
-      getCrossReferences(seq);
+      getCrossReferences(seqs.get(i));
     }
 
     return alignment;
@@ -209,12 +210,19 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
       SequenceI genomicSequence = null;
       EnsemblFeatures gffFetcher = new EnsemblFeatures(getDomain());
       EnsemblFeatureType[] features = getFeaturesToFetch();      
+      
+      Platform.timeCheck("ESP.getsequencerec1", Platform.TIME_MARK);     
+
+      
       AlignmentI geneFeatures = gffFetcher.getSequenceRecords(accId,
               features);
       if (geneFeatures != null && geneFeatures.getHeight() > 0)
       {
         genomicSequence = geneFeatures.getSequenceAt(0);
       }
+      
+      Platform.timeCheck("ESP.getsequencerec2", Platform.TIME_MARK);     
+      
       if (genomicSequence != null)
       {
         /*
@@ -228,6 +236,7 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
            * fetch and map protein product, and add it as a cross-reference
            * of the retrieved sequence
            */
+            Platform.timeCheck("ESP.transferFeatures", Platform.TIME_MARK);      
           addProteinProduct(querySeq);
         }
       }
@@ -236,6 +245,7 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
       System.err.println(
               "Error transferring Ensembl features: " + e.getMessage());
     }
+    Platform.timeCheck("ESP.addfeat done", Platform.TIME_MARK);          
   }
 
   /**
@@ -348,28 +358,47 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
    */
   protected void getCrossReferences(SequenceI seq)
   {
+         
+      Platform.timeCheck("ESP. getdataseq ", Platform.TIME_MARK);        
+
+         
     while (seq.getDatasetSequence() != null)
     {
       seq = seq.getDatasetSequence();
     }
+
+    Platform.timeCheck("ESP. getxref ", Platform.TIME_MARK);     
+
     EnsemblXref xrefFetcher = new EnsemblXref(getDomain(), getDbSource(),
             getEnsemblDataVersion());
     List<DBRefEntry> xrefs = xrefFetcher.getCrossReferences(seq.getName());
     
     for (int i = 0, n = xrefs.size(); i < n; i++)
     {
+//        Platform.timeCheck("ESP. getxref + " + (i) + "/" + n, Platform.TIME_MARK);     
         // BH 2019.01.25 this next method was taking 174 ms PER addition for a 266-reference example.
         //    DBRefUtils.ensurePrimaries(seq) 
         //        was at the end of seq.addDBRef, so executed after ever addition!
         //        This method was moved to     seq.getPrimaryDBRefs()
       seq.addDBRef(xrefs.get(i));
     }
+
+//    System.out.println("primaries are " + seq.getPrimaryDBRefs().toString());
     /*
      * and add a reference to itself
      */
+    
+//    Platform.timeCheck("ESP. getxref self ", Platform.TIME_MARK);      
+
     DBRefEntry self = new DBRefEntry(getDbSource(), getEnsemblDataVersion(),
     seq.getName());
+
+//    Platform.timeCheck("ESP. getxref self add ", Platform.TIME_MARK);          
+
     seq.addDBRef(self);
+    
+    Platform.timeCheck("ESP. seqprox done ", Platform.TIME_MARK);        
+
   }
 
   /**
@@ -390,6 +419,8 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
       inProgress = false;
       throw new JalviewException("ENSEMBL Rest API not available.");
     }
+       Platform.timeCheck("EnsemblSeqProx.fetchSeq ", Platform.TIME_MARK);
+
     List<SequenceI> seqs = parseSequenceJson(ids);
     if (seqs == null)
        return alignment;
@@ -455,6 +486,8 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
        * for now, assumes only one sequence returned; refactor if needed
        * in future to handle a JSONArray with more than one
        */
+       
+       Platform.timeCheck("ENS seqproxy", Platform.TIME_MARK);
       Map<String, Object> val = (Map<String, Object>) getJSON(null, ids, -1, MODE_MAP, null);
       if (val == null)
          return null;
@@ -480,6 +513,7 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
       System.err.println("Error processing JSON response: " + e.toString());
       // ignore
     }
+       Platform.timeCheck("ENS seqproxy2", Platform.TIME_MARK);
     return result;
   }
 
@@ -659,7 +693,9 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
    */
   protected abstract List<SequenceFeature> getIdentifyingFeatures(
           SequenceI seq, String accId);
-
+  
+  int bhtest = 0;
+  
   /**
    * Transfers the sequence feature to the target sequence, locating its start
    * and end range based on the mapping. Features which do not overlap the
@@ -681,6 +717,7 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
 
     if (mappedRange != null)
     {
+//      Platform.timeCheck(null, Platform.TIME_SET);
       String group = sf.getFeatureGroup();
       if (".".equals(group))
       {
@@ -688,8 +725,11 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
       }
       int newBegin = Math.min(mappedRange[0], mappedRange[1]);
       int newEnd = Math.max(mappedRange[0], mappedRange[1]);
-      SequenceFeature copy = new SequenceFeature(sf, newBegin, newEnd,
-              group, sf.getScore());
+//      Platform.timeCheck(null, Platform.TIME_MARK);
+      bhtest++;
+      // 280 ms/1000 here:
+      SequenceFeature copy = new SequenceFeature(sf, newBegin, newEnd, group, sf.getScore());
+      // 0.175 ms here:
       targetSequence.addSequenceFeature(copy);
 
       /*
@@ -794,10 +834,14 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
     MapList mapping = getGenomicRangesFromFeatures(sourceSequence,
             accessionId, targetSequence.getStart());
     if (mapping == null)
-    {
+    { 
       return false;
     }
 
+
+    Platform.timeCheck("ESP. xfer " + sfs.size(), Platform.TIME_MARK);   
+
+
     boolean result = transferFeatures(sfs, targetSequence, mapping,
             accessionId);
 //    System.out.println("transferFeatures (" + (sfs.size()) + " --> "
@@ -831,14 +875,23 @@ public abstract class EnsemblSeqProxy extends EnsemblRestClient
     SequenceFeatures.sortFeatures(sfs, forwardStrand);
 
     boolean transferred = false;
-    for (SequenceFeature sf : sfs)
+    
+    for (int i = 0, n = sfs.size(); i < n; i++)
     {
+
+//     if ((i%1000) == 0) {
+////               Platform.timeCheck("Feature " + bhtest, Platform.TIME_GET);
+//     Platform.timeCheck("ESP. xferFeature + " + (i) + "/" + n, Platform.TIME_MARK);    
+//     }
+
+      SequenceFeature sf = sfs.get(i);
       if (retainFeature(sf, parentId))
       {
         transferFeature(sf, targetSequence, mapping, forwardStrand);
         transferred = true;
       }
     }
+
     return transferred;
   }
 
index a50a2e6..30c37de 100644 (file)
@@ -2801,6 +2801,8 @@ public class Desktop extends jalview.jbgui.GDesktop
   @Override
   public void setProgressBar(String message, long id)
   {
+           Platform.timeCheck("Desktop " + message, Platform.TIME_MARK);     
+
     if (progressBars == null)
     {
       progressBars = new Hashtable<>();
index 6cb7cb5..1c3ac98 100644 (file)
@@ -28,95 +28,6 @@ import java.util.List;
 public class JSON {
 
        /**
-        * A privately initialized class that allows us to do the object
-        * conversion from JavaScript to "Java" on the fly. 
-        * 
-        * @author hansonr
-        *
-        */
-       @SuppressWarnings("serial")
-       public static class JSONList extends ArrayList<Object>  {
-
-
-               static ListIterator iter;
-               
-               JSONList(Object[] a) {
-                       super();
-                       /**
-                        * @j2sNative
-                        * 
-                        * this.elementData = a;
-                        * this.size = a.length;
-                        */
-               }
-               
-               public Object get(int i) {
-                       Object o = null;
-                       /**
-                        * @j2sNative
-                        * 
-                        *  o = this.elementData[i]; 
-                        *  
-                        */
-                       return JSON.toObject(o);
-               }
-
-
-               @Override
-               public Iterator<Object> iterator() {
-                       if (iter == null)
-                               iter = new ListIterator();
-                       iter.pt = 0;
-                       iter.list = this;
-                       return iter;
-               }
-
-               
-               /**
-                * 
-                * @author hansonr
-                *
-                */
-               public static class ListIterator implements Iterator<Object> {
-
-                       ListIterator() {/* restricted */}
-                       
-                       public JSONList list;
-                       int pt = -1;
-
-                       @Override
-                       public boolean hasNext() {
-                               @SuppressWarnings("unused")
-                               boolean more;
-                               /**
-                                * @j2sNative
-                                * 
-                                * more = this.list && (this.pt < this.list.size);
-                                * if (!more) {
-                                *   this.list = null;
-                                *   this.pt = -1;
-                                * }
-                                * return more; 
-                                */
-                               {
-                               return pt < list.size();
-                               }
-                       }
-
-                       @Override
-                       public Object next() {
-                               Object o = null;
-                               /**
-                                * @j2sNative o = this.list.elementData[this.pt++];
-                                * 
-                                */
-                               
-                               return toObject(o);                             
-                       }
-               }
-       }
-
-       /**
         * A simple encoding of sequential key/value pairs for a jQuery.ajax call. If
         * the first key is "url" and the second is an object, then the ajax object is
         * attached to that url as well, just for transport purposes within the system.
@@ -124,132 +35,26 @@ public class JSON {
         * @param keyValues assumed to be simple String,Object pairs. String objects
         *                  will be surrounded by double quotes.
         */
+       @SuppressWarnings("static-access")
        public static Object setAjax(Object... keyValues) {
-               Object ajax = null;
-               /**
-                * @j2sNative ajax = {}; if (keyValues[0] == "url" && typeof keyValues[1] ==
-                *            "object") { ajax = keyValues[1].ajax || (keyValues[1].ajax = ajax); }
-                * 
-                *            for (var i = 0; i < keyValues.length;) { var key = keyValues[i++];
-                *            var val = keyValues[i++]; ajax[key] = val; }
-                */
-               return ajax;
+               return /** @j2sNative swingjs.JSUtil.setAjax$OA(keyValues) || */null;
        }
 
        public static void setAjax(URL url) {
-               setAjax("url", url, "dataType", "json", "async", Boolean.FALSE);        
+               /** @j2sNative swingjs.JSUtil.setAjax$O(url) */;
        }
 
        public static BufferedReader getJSONReader(InputStream is) {
-               return new JSONReader(is);
-       }
-
-       public static class JSONReader extends BufferedReader {
-               Object data;
-
-               public JSONReader(InputStream in) {
-                       super((Reader) (Object) in);
-                       // could be buffered
-                       data = toObject(/** @j2sNative $in._ajaxData || $in.$in && $in.$in._ajaxData || */ null);
-                       
-               }
-
-               public JSONReader(Reader in) {
-                       super(in);
-                       // could be buffered
-                       data = toObject(/** @j2sNative $in._ajaxData || $in.$in && $in.$in._ajaxData || */ null);
-               }
-
-               public JSONReader(String json) {
-                       super((Reader) (Object) "");
-                       data = toObject(/** @j2sNative  swingjs.JSUtil.parseJSON$S(json)|| */null); 
-               }
-
-               @Override
-               public void close() {
-                       data = null;
-                       try {
-                               super.close();
-                       } catch (IOException e) {
-                               // ignore, especially if we set $in to a string!
-                       }
-               }
+               return /** @j2sNative swingjs.JSUtil.getJSONReader$O(is) || */null;
        }
 
        @SuppressWarnings("resource")
-       public static Object parse(String json) {
-               return new JSONReader(json).data;
+       public static Object parse(String json) {  
+               return /** @j2sNative swingjs.JSUtil.parseJSON$O(json) || */null;
        }
 
        public static Object parse(Reader br) {
-               return ((JSONReader) br).data;
-       }
-
-       /**
-        * Get an object in the JSON associative array.
-        * @param br
-        * @param key
-        * @return
-        */
-       @SuppressWarnings("unused")
-       public static Object toObject(Object o) {
-               if (o == null)
-                       return null;
-               String type = /** @j2sNative (typeof o) + */"";
-               switch (type) {
-               case "string":
-                       return o;
-               case "number":
-                       double n = 0;
-                       if (/** @j2sNative (n = o) == (n|0) || */false)
-                               return Long.valueOf((long) n);
-                       return Double.valueOf(n);
-               case "boolean":
-                       return Boolean.valueOf(/** @j2sNative !!o || */false);
-               case "object":
-                       boolean isArray =  /** @j2sNative o instanceof Array || */false;
-                       if (isArray) {
-                               return toList((Object[]) o);
-                       }
-                       return toMap(o);
-               default:
-                       return o;
-               }
-       }
-       
-       Object get(String key) {
-               /**
-                * @j2sNative
-                * 
-                *  return C$.toObject$O(this[key]);
-                */
-               {
-                       return null;
-               }
-       }
-       boolean contains(String key) {
-               /**
-                * @j2sNative
-                * 
-                *  return typeof this[key] != "undefined"
-                */
-               {
-                       return false;
-               }
-       }
-       
-       @SuppressWarnings("unchecked")
-       private static Hashtable<String, Object> toMap(Object map) {
-               /**
-                * @j2sNative
-                * map.get$O = C$.prototype.get$S;
-                * map.contains$O = C$.prototype.contains$S;
-                */                     
-               return (Hashtable<String, Object>) map;
-       }
-
-       private static List<Object> toList(Object[] a) {
-               return new JSONList(a);
+               return /** @j2sNative swingjs.JSUtil.parseJSON$O(br) || */null;
        }
 
 }
index 286ded1..0b9185c 100644 (file)
@@ -201,21 +201,37 @@ public class Platform
   
   public final static int TIME_RESET = 0;
   public final static int TIME_MARK  = 1;
+  public static final int TIME_SET   = 2;
+  public static final int TIME_GET   = 3;
   
-  public static long time, mark;
+  public static long time, mark, set, duration;
   
   public static void timeCheck(String msg, int mode) {
+         long t = System.currentTimeMillis();
          switch (mode) {
          case TIME_RESET:
-                 time = mark = System.currentTimeMillis();
-                 System.err.println("Platform: timer reset\t\t\t" + msg);
+                 time = mark = t;
+                 if (msg != null)
+                         System.err.println("Platform: timer reset\t\t\t" + msg);
                  break;
          case TIME_MARK:
-                 long t = System.currentTimeMillis();
-                 if (time == 0)
-                         time = mark = t;
-                 System.err.println("Platform: timer mark\t" + ((t - time)/1000f) + "\t" + ((t - mark)/1000f) + "\t" + msg);
-                 mark = t;
+                 if (set > 0) {
+                         duration += (t - set);
+                 } else {
+                         if (time == 0)
+                                 time = mark = t;
+                         if (msg != null)
+                                 System.err.println("Platform: timer mark\t" + ((t - time)/1000f) + "\t" + ((t - mark)/1000f) + "\t" + msg);
+                         mark = t;
+                 }
+                 break;
+         case TIME_SET:
+                 set = t;
+                 break;
+         case TIME_GET:
+                 if (msg != null)
+                         System.err.println("Platform: timer dur\t" + ((t - time)/1000f) + "\t" + ((duration)/1000f) + "\t" + msg);
+                 set = 0;
                  break;
          }
   }
index 9189041..7079c67 100644 (file)
Binary files a/swingjs/SwingJS-site.zip and b/swingjs/SwingJS-site.zip differ
index 2250555..4f24039 100644 (file)
@@ -1 +1 @@
-20190125104925 
+20190129013326 
index 9189041..7079c67 100644 (file)
Binary files a/swingjs/ver/3.2.4/SwingJS-site.zip and b/swingjs/ver/3.2.4/SwingJS-site.zip differ
index c5dae25..4f24039 100644 (file)
@@ -1 +1 @@
-20190125031511 
+20190129013326 
diff --git a/unused/AlignmentAnnotation.java b/unused/AlignmentAnnotation.java
new file mode 100644 (file)
index 0000000..e9ca0c4
--- /dev/null
@@ -0,0 +1,1718 @@
+/*
+ * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
+ * Copyright (C) $$Year-Rel$$ The Jalview Authors
+ * 
+ * This file is part of Jalview.
+ * 
+ * Jalview is free software: you can redistribute it and/or
+ * modify it under the terms of the GNU General Public License 
+ * as published by the Free Software Foundation, either version 3
+ * of the License, or (at your option) any later version.
+ *  
+ * Jalview is distributed in the hope that it will be useful, but 
+ * WITHOUT ANY WARRANTY; without even the implied warranty 
+ * of MERCHANTABILITY or FITNESS FOR A PARTICULAR 
+ * PURPOSE.  See the GNU General Public License for more details.
+ * 
+ * You should have received a copy of the GNU General Public License
+ * along with Jalview.  If not, see <http://www.gnu.org/licenses/>.
+ * The Jalview Authors are detailed in the 'AUTHORS' file.
+ */
+package jalview.datamodel;
+
+import jalview.analysis.Rna;
+import jalview.analysis.SecStrConsensus.SimpleBP;
+import jalview.analysis.WUSSParseException;
+import jalview.util.MapList;
+
+import java.util.ArrayList;
+import java.util.Arrays;
+import java.util.Collection;
+import java.util.Collections;
+import java.util.HashMap;
+import java.util.Iterator;
+import java.util.List;
+import java.util.Map;
+import java.util.Map.Entry;
+
+/**
+ * DOCUMENT ME!
+ * 
+ * @author $author$
+ * @version $Revision$
+ */
+public class AlignmentAnnotation
+{
+  private static final String ANNOTATION_ID_PREFIX = "ann";
+
+  /*
+   * Identifers for different types of profile data
+   */
+  public static final int SEQUENCE_PROFILE = 0;
+
+  public static final int STRUCTURE_PROFILE = 1;
+
+  public static final int CDNA_PROFILE = 2;
+
+  private static long counter = 0;
+
+  /**
+   * If true, this annotations is calculated every edit, eg consensus, quality
+   * or conservation graphs
+   */
+  public boolean autoCalculated = false;
+
+  /**
+   * unique ID for this annotation, used to match up the same annotation row
+   * shown in multiple views and alignments
+   */
+  public String annotationId;
+
+  /**
+   * the sequence this annotation is associated with (or null)
+   */
+  public SequenceI sequenceRef;
+
+  /** label shown in dropdown menus and in the annotation label area */
+  public String label;
+
+  /** longer description text shown as a tooltip */
+  public String description;
+
+  /** Array of annotations placed in the current coordinate system */
+  public Annotation[] annotations;
+
+  public List<SimpleBP> bps = null;
+
+  /**
+   * RNA secondary structure contact positions
+   */
+  public SequenceFeature[] _rnasecstr = null;
+
+  /**
+   * position of annotation resulting in invalid WUSS parsing or -1. -2 means
+   * there was no RNA structure in this annotation
+   */
+  private long invalidrnastruc = -2;
+
+  /**
+   * Updates the _rnasecstr field Determines the positions that base pair and
+   * the positions of helices based on secondary structure from a Stockholm file
+   * 
+   * @param rnaAnnotation
+   */
+  private void _updateRnaSecStr(CharSequence rnaAnnotation)
+  {
+    try
+    {
+      _rnasecstr = Rna.getHelixMap(rnaAnnotation);
+      invalidrnastruc = -1;
+    } catch (WUSSParseException px)
+    {
+      // DEBUG System.out.println(px);
+      invalidrnastruc = px.getProblemPos();
+    }
+    if (invalidrnastruc > -1)
+    {
+      return;
+    }
+
+    if (_rnasecstr != null && _rnasecstr.length > 0)
+    {
+      // show all the RNA secondary structure annotation symbols.
+      isrna = true;
+      showAllColLabels = true;
+      scaleColLabel = true;
+      _markRnaHelices();
+    }
+    // System.out.println("featuregroup " + _rnasecstr[0].getFeatureGroup());
+
+  }
+
+  private void _markRnaHelices()
+  {
+    int mxval = 0;
+    // Figure out number of helices
+    // Length of rnasecstr is the number of pairs of positions that base pair
+    // with each other in the secondary structure
+    for (int x = 0; x < _rnasecstr.length; x++)
+    {
+
+      /*
+       * System.out.println(this.annotation._rnasecstr[x] + " Begin" +
+       * this.annotation._rnasecstr[x].getBegin());
+       */
+      // System.out.println(this.annotation._rnasecstr[x].getFeatureGroup());
+      int val = 0;
+      try
+      {
+        val = Integer.valueOf(_rnasecstr[x].getFeatureGroup());
+        if (mxval < val)
+        {
+          mxval = val;
+        }
+      } catch (NumberFormatException q)
+      {
+      }
+      ;
+
+      annotations[_rnasecstr[x].getBegin()].value = val;
+      annotations[_rnasecstr[x].getEnd()].value = val;
+
+      // annotations[_rnasecstr[x].getBegin()].displayCharacter = "" + val;
+      // annotations[_rnasecstr[x].getEnd()].displayCharacter = "" + val;
+    }
+    setScore(mxval);
+  }
+
+  /**
+   * Get the RNA Secondary Structure SequenceFeature Array if present
+   */
+  public SequenceFeature[] getRnaSecondaryStructure()
+  {
+    return this._rnasecstr;
+  }
+
+  /**
+   * Check the RNA Secondary Structure is equivalent to one in given
+   * AlignmentAnnotation param
+   */
+  public boolean rnaSecondaryStructureEquivalent(AlignmentAnnotation that)
+  {
+    return rnaSecondaryStructureEquivalent(that, true);
+  }
+
+  public boolean rnaSecondaryStructureEquivalent(AlignmentAnnotation that, boolean compareType)
+  {
+    SequenceFeature[] thisSfArray = this.getRnaSecondaryStructure();
+    SequenceFeature[] thatSfArray = that.getRnaSecondaryStructure();
+    if (thisSfArray == null || thatSfArray == null)
+    {
+      return thisSfArray == null && thatSfArray == null;
+    }
+    if (thisSfArray.length != thatSfArray.length)
+    {
+      return false;
+    }
+    Arrays.sort(thisSfArray, new SFSortByEnd()); // probably already sorted
+                                                   // like this
+    Arrays.sort(thatSfArray, new SFSortByEnd()); // probably already sorted
+                                                   // like this
+    for (int i=0; i < thisSfArray.length; i++) {
+      SequenceFeature thisSf = thisSfArray[i];
+      SequenceFeature thatSf = thatSfArray[i];
+      if (compareType) {
+        if (thisSf.getType() == null || thatSf.getType() == null) {
+          if (thisSf.getType() == null && thatSf.getType() == null) {
+            continue;
+          } else {
+            return false;
+          }
+        }
+        if (! thisSf.getType().equals(thatSf.getType())) {
+          return false;
+        }
+      }
+      if (!(thisSf.getBegin() == thatSf.getBegin()
+              && thisSf.getEnd() == thatSf.getEnd()))
+      {
+        return false;
+      }
+    }
+    return true;
+
+  }
+
+  /**
+   * map of positions in the associated annotation
+   */
+  private Map<Integer, Annotation> sequenceMapping;
+
+  /**
+   * lower range for quantitative data
+   */
+  public float graphMin;
+
+  /**
+   * Upper range for quantitative data
+   */
+  public float graphMax;
+
+  /**
+   * Score associated with label and description.
+   */
+  public double score = Double.NaN;
+
+  /**
+   * flag indicating if annotation has a score.
+   */
+  public boolean hasScore = false;
+
+  public GraphLine threshold;
+
+  // Graphical hints and tips
+
+  /** Can this row be edited by the user ? */
+  public boolean editable = false;
+
+  /** Indicates if annotation has a graphical symbol track */
+  public boolean hasIcons; //
+
+  /** Indicates if annotation has a text character label */
+  public boolean hasText;
+
+  /** is the row visible */
+  public boolean visible = true;
+
+  public int graphGroup = -1;
+
+  /** Displayed height of row in pixels */
+  public int height = 0;
+
+  public int graph = 0;
+
+  public int graphHeight = 40;
+
+  public boolean padGaps = false;
+
+  public static final int NO_GRAPH = 0;
+
+  public static final int BAR_GRAPH = 1;
+
+  public static final int LINE_GRAPH = 2;
+
+  public boolean belowAlignment = true;
+
+  public SequenceGroup groupRef = null;
+
+  /**
+   * display every column label, even if there is a row of identical labels
+   */
+  public boolean showAllColLabels = false;
+
+  /**
+   * scale the column label to fit within the alignment column.
+   */
+  public boolean scaleColLabel = false;
+
+  /**
+   * centre the column labels relative to the alignment column
+   */
+  public boolean centreColLabels = false;
+
+  private boolean isrna;
+
+  public static int getGraphValueFromString(String string)
+  {
+    if (string.equalsIgnoreCase("BAR_GRAPH"))
+    {
+      return BAR_GRAPH;
+    }
+    else if (string.equalsIgnoreCase("LINE_GRAPH"))
+    {
+      return LINE_GRAPH;
+    }
+    else
+    {
+      return NO_GRAPH;
+    }
+  }
+
+  /**
+   * Creates a new AlignmentAnnotation object.
+   * 
+   * @param label
+   *          short label shown under sequence labels
+   * @param description
+   *          text displayed on mouseover
+   * @param annotations
+   *          set of positional annotation elements
+   */
+  public AlignmentAnnotation(String label, String description,
+          Annotation[] annotations)
+  {
+    setAnnotationId();
+    // always editable?
+    editable = true;
+    this.label = label;
+    this.description = description;
+    this.annotations = annotations;
+
+    validateRangeAndDisplay();
+  }
+
+  /**
+   * Checks if annotation labels represent secondary structures
+   * 
+   */
+  void areLabelsSecondaryStructure()
+  {
+    boolean nonSSLabel = false;
+    isrna = false;
+    StringBuffer rnastring = new StringBuffer();
+
+    char firstChar = 0;
+    for (int i = 0; i < annotations.length; i++)
+    {
+      // DEBUG System.out.println(i + ": " + annotations[i]);
+      if (annotations[i] == null)
+      {
+        continue;
+      }
+      if (annotations[i].secondaryStructure == 'H'
+              || annotations[i].secondaryStructure == 'E')
+      {
+        // DEBUG System.out.println( "/H|E/ '" +
+        // annotations[i].secondaryStructure + "'");
+        hasIcons |= true;
+      }
+      else
+      // Check for RNA secondary structure
+      {
+        // DEBUG System.out.println( "/else/ '" +
+        // annotations[i].secondaryStructure + "'");
+        // TODO: 2.8.2 should this ss symbol validation check be a function in
+        // RNA/ResidueProperties ?
+        if (annotations[i].secondaryStructure == '('
+                || annotations[i].secondaryStructure == '['
+                || annotations[i].secondaryStructure == '<'
+                || annotations[i].secondaryStructure == '{'
+                || annotations[i].secondaryStructure == 'A'
+                || annotations[i].secondaryStructure == 'B'
+                || annotations[i].secondaryStructure == 'C'
+                || annotations[i].secondaryStructure == 'D'
+                // || annotations[i].secondaryStructure == 'E' // ambiguous on
+                // its own -- already checked above
+                || annotations[i].secondaryStructure == 'F'
+                || annotations[i].secondaryStructure == 'G'
+                // || annotations[i].secondaryStructure == 'H' // ambiguous on
+                // its own -- already checked above
+                || annotations[i].secondaryStructure == 'I'
+                || annotations[i].secondaryStructure == 'J'
+                || annotations[i].secondaryStructure == 'K'
+                || annotations[i].secondaryStructure == 'L'
+                || annotations[i].secondaryStructure == 'M'
+                || annotations[i].secondaryStructure == 'N'
+                || annotations[i].secondaryStructure == 'O'
+                || annotations[i].secondaryStructure == 'P'
+                || annotations[i].secondaryStructure == 'Q'
+                || annotations[i].secondaryStructure == 'R'
+                || annotations[i].secondaryStructure == 'S'
+                || annotations[i].secondaryStructure == 'T'
+                || annotations[i].secondaryStructure == 'U'
+                || annotations[i].secondaryStructure == 'V'
+                || annotations[i].secondaryStructure == 'W'
+                || annotations[i].secondaryStructure == 'X'
+                || annotations[i].secondaryStructure == 'Y'
+                || annotations[i].secondaryStructure == 'Z')
+        {
+          hasIcons |= true;
+          isrna |= true;
+        }
+      }
+
+      // System.out.println("displaychar " + annotations[i].displayCharacter);
+
+      if (annotations[i].displayCharacter == null
+              || annotations[i].displayCharacter.length() == 0)
+      {
+        rnastring.append('.');
+        continue;
+      }
+      if (annotations[i].displayCharacter.length() == 1)
+      {
+        firstChar = annotations[i].displayCharacter.charAt(0);
+        // check to see if it looks like a sequence or is secondary structure
+        // labelling.
+        if (annotations[i].secondaryStructure != ' ' && !hasIcons &&
+        // Uncomment to only catch case where
+        // displayCharacter==secondary
+        // Structure
+        // to correctly redisplay SS annotation imported from Stockholm,
+        // exported to JalviewXML and read back in again.
+        // &&
+        // annotations[i].displayCharacter.charAt(0)==annotations[i].secondaryStructure
+                firstChar != ' ' && firstChar != '$' && firstChar != 0xCE
+                && firstChar != '(' && firstChar != '[' && firstChar != '<'
+                && firstChar != '{' && firstChar != 'A' && firstChar != 'B'
+                && firstChar != 'C' && firstChar != 'D' && firstChar != 'E'
+                && firstChar != 'F' && firstChar != 'G' && firstChar != 'H'
+                && firstChar != 'I' && firstChar != 'J' && firstChar != 'K'
+                && firstChar != 'L' && firstChar != 'M' && firstChar != 'N'
+                && firstChar != 'O' && firstChar != 'P' && firstChar != 'Q'
+                && firstChar != 'R' && firstChar != 'S' && firstChar != 'T'
+                && firstChar != 'U' && firstChar != 'V' && firstChar != 'W'
+                && firstChar != 'X' && firstChar != 'Y' && firstChar != 'Z'
+                && firstChar != '-'
+                && firstChar < jalview.schemes.ResidueProperties.aaIndex.length)
+        {
+          if (jalview.schemes.ResidueProperties.aaIndex[firstChar] < 23) // TODO:
+                                                                         // parameterise
+                                                                         // to
+                                                                         // gap
+                                                                         // symbol
+                                                                         // number
+          {
+            nonSSLabel = true;
+          }
+        }
+      }
+      else
+      {
+        rnastring.append(annotations[i].displayCharacter.charAt(1));
+      }
+
+      if (annotations[i].displayCharacter.length() > 0)
+      {
+        hasText = true;
+      }
+    }
+
+    if (nonSSLabel)
+    {
+      hasIcons = false;
+      for (int j = 0; j < annotations.length; j++)
+      {
+        if (annotations[j] != null
+                && annotations[j].secondaryStructure != ' ')
+        {
+          annotations[j].displayCharacter = String
+                  .valueOf(annotations[j].secondaryStructure);
+          annotations[j].secondaryStructure = ' ';
+        }
+
+      }
+    }
+    else
+    {
+      if (isrna)
+      {
+        _updateRnaSecStr(new AnnotCharSequence());
+      }
+    }
+  }
+
+  /**
+   * flyweight access to positions in the alignment annotation row for RNA
+   * processing
+   * 
+   * @author jimp
+   * 
+   */
+  private class AnnotCharSequence implements CharSequence
+  {
+    int offset = 0;
+
+    int max = 0;
+
+    public AnnotCharSequence()
+    {
+      this(0, annotations.length);
+    }
+
+    AnnotCharSequence(int start, int end)
+    {
+      offset = start;
+      max = end;
+    }
+
+    @Override
+    public CharSequence subSequence(int start, int end)
+    {
+      return new AnnotCharSequence(offset + start, offset + end);
+    }
+
+    @Override
+    public int length()
+    {
+      return max - offset;
+    }
+
+    @Override
+    public char charAt(int index)
+    {
+      return ((index + offset < 0) || (index + offset) >= max
+              || annotations[index + offset] == null
+              || (annotations[index + offset].secondaryStructure <= ' ')
+                      ? ' '
+                      : annotations[index + offset].displayCharacter == null
+                              || annotations[index
+                                      + offset].displayCharacter
+                                              .length() == 0
+                                                      ? annotations[index
+                                                              + offset].secondaryStructure
+                                                      : annotations[index
+                                                              + offset].displayCharacter
+                                                                      .charAt(0));
+    }
+
+    @Override
+    public String toString()
+    {
+      char[] string = new char[max - offset];
+      int mx = annotations.length;
+
+      for (int i = offset; i < mx; i++)
+      {
+        string[i] = (annotations[i] == null
+                || (annotations[i].secondaryStructure <= 32))
+                        ? ' '
+                        : (annotations[i].displayCharacter == null
+                                || annotations[i].displayCharacter
+                                        .length() == 0
+                                                ? annotations[i].secondaryStructure
+                                                : annotations[i].displayCharacter
+                                                        .charAt(0));
+      }
+      return new String(string);
+    }
+  };
+
+  private long _lastrnaannot = -1;
+
+  public String getRNAStruc()
+  {
+    if (isrna)
+    {
+      String rnastruc = new AnnotCharSequence().toString();
+      if (_lastrnaannot != rnastruc.hashCode())
+      {
+        // ensure rna structure contacts are up to date
+        _lastrnaannot = rnastruc.hashCode();
+        _updateRnaSecStr(rnastruc);
+      }
+      return rnastruc;
+    }
+    return null;
+  }
+
+  /**
+   * Creates a new AlignmentAnnotation object.
+   * 
+   * @param label
+   *          DOCUMENT ME!
+   * @param description
+   *          DOCUMENT ME!
+   * @param annotations
+   *          DOCUMENT ME!
+   * @param min
+   *          DOCUMENT ME!
+   * @param max
+   *          DOCUMENT ME!
+   * @param winLength
+   *          DOCUMENT ME!
+   */
+  public AlignmentAnnotation(String label, String description,
+          Annotation[] annotations, float min, float max, int graphType)
+  {
+    setAnnotationId();
+    // graphs are not editable
+    editable = graphType == 0;
+
+    this.label = label;
+    this.description = description;
+    this.annotations = annotations;
+    graph = graphType;
+    graphMin = min;
+    graphMax = max;
+    validateRangeAndDisplay();
+  }
+
+  /**
+   * checks graphMin and graphMax, secondary structure symbols, sets graphType
+   * appropriately, sets null labels to the empty string if appropriate.
+   */
+  public void validateRangeAndDisplay()
+  {
+
+    if (annotations == null)
+    {
+      visible = false; // try to prevent renderer from displaying.
+      invalidrnastruc = -1;
+      return; // this is a non-annotation row annotation - ie a sequence score.
+    }
+
+    int graphType = graph;
+    float min = graphMin;
+    float max = graphMax;
+    boolean drawValues = true;
+    _linecolour = null;
+    if (min == max)
+    {
+      min = 999999999;
+      for (int i = 0; i < annotations.length; i++)
+      {
+        if (annotations[i] == null)
+        {
+          continue;
+        }
+
+        if (drawValues && annotations[i].displayCharacter != null
+                && annotations[i].displayCharacter.length() > 1)
+        {
+          drawValues = false;
+        }
+
+        if (annotations[i].value > max)
+        {
+          max = annotations[i].value;
+        }
+
+        if (annotations[i].value < min)
+        {
+          min = annotations[i].value;
+        }
+        if (_linecolour == null && annotations[i].colour != null)
+        {
+          _linecolour = annotations[i].colour;
+        }
+      }
+      // ensure zero is origin for min/max ranges on only one side of zero
+      if (min > 0)
+      {
+        min = 0;
+      }
+      else
+      {
+        if (max < 0)
+        {
+          max = 0;
+        }
+      }
+    }
+
+    graphMin = min;
+    graphMax = max;
+
+    areLabelsSecondaryStructure();
+
+    if (!drawValues && graphType != NO_GRAPH)
+    {
+      for (int i = 0; i < annotations.length; i++)
+      {
+        if (annotations[i] != null)
+        {
+          annotations[i].displayCharacter = "";
+        }
+      }
+    }
+  }
+
+  /**
+   * Copy constructor creates a new independent annotation row with the same
+   * associated sequenceRef
+   * 
+   * @param annotation
+   */
+  public AlignmentAnnotation(AlignmentAnnotation annotation)
+  {
+    setAnnotationId();
+    this.label = new String(annotation.label);
+    if (annotation.description != null)
+    {
+      this.description = new String(annotation.description);
+    }
+    this.graphMin = annotation.graphMin;
+    this.graphMax = annotation.graphMax;
+    this.graph = annotation.graph;
+    this.graphHeight = annotation.graphHeight;
+    this.graphGroup = annotation.graphGroup;
+    this.groupRef = annotation.groupRef;
+    this.editable = annotation.editable;
+    this.autoCalculated = annotation.autoCalculated;
+    this.hasIcons = annotation.hasIcons;
+    this.hasText = annotation.hasText;
+    this.height = annotation.height;
+    this.label = annotation.label;
+    this.padGaps = annotation.padGaps;
+    this.visible = annotation.visible;
+    this.centreColLabels = annotation.centreColLabels;
+    this.scaleColLabel = annotation.scaleColLabel;
+    this.showAllColLabels = annotation.showAllColLabels;
+    this.calcId = annotation.calcId;
+    if (annotation.properties != null)
+    {
+      properties = new HashMap<>();
+      for (Map.Entry<String, String> val : annotation.properties.entrySet())
+      {
+        properties.put(val.getKey(), val.getValue());
+      }
+    }
+    if (this.hasScore = annotation.hasScore)
+    {
+      this.score = annotation.score;
+    }
+    if (annotation.threshold != null)
+    {
+      threshold = new GraphLine(annotation.threshold);
+    }
+    Annotation[] ann = annotation.annotations;
+    if (annotation.annotations != null)
+    {
+      this.annotations = new Annotation[ann.length];
+      for (int i = 0; i < ann.length; i++)
+      {
+        if (ann[i] != null)
+        {
+          annotations[i] = new Annotation(ann[i]);
+          if (_linecolour != null)
+          {
+            _linecolour = annotations[i].colour;
+          }
+        }
+      }
+    }
+    if (annotation.sequenceRef != null)
+    {
+      this.sequenceRef = annotation.sequenceRef;
+      if (annotation.sequenceMapping != null)
+      {
+        Integer p = null;
+        sequenceMapping = new HashMap<>();
+        Iterator<Integer> pos = annotation.sequenceMapping.keySet()
+                .iterator();
+        while (pos.hasNext())
+        {
+          // could optimise this!
+          p = pos.next();
+          Annotation a = annotation.sequenceMapping.get(p);
+          if (a == null)
+          {
+            continue;
+          }
+          if (ann != null)
+          {
+            for (int i = 0; i < ann.length; i++)
+            {
+              if (ann[i] == a)
+              {
+                sequenceMapping.put(p, annotations[i]);
+              }
+            }
+          }
+        }
+      }
+      else
+      {
+        this.sequenceMapping = null;
+      }
+    }
+    // TODO: check if we need to do this: JAL-952
+    // if (this.isrna=annotation.isrna)
+    {
+      // _rnasecstr=new SequenceFeature[annotation._rnasecstr];
+    }
+    validateRangeAndDisplay(); // construct hashcodes, etc.
+  }
+
+  /**
+   * clip the annotation to the columns given by startRes and endRes (inclusive)
+   * and prune any existing sequenceMapping to just those columns.
+   * 
+   * @param startRes
+   * @param endRes
+   */
+  public void restrict(int startRes, int endRes)
+  {
+    if (annotations == null)
+    {
+      // non-positional
+      return;
+    }
+    if (startRes < 0)
+    {
+      startRes = 0;
+    }
+    if (startRes >= annotations.length)
+    {
+      startRes = annotations.length - 1;
+    }
+    if (endRes >= annotations.length)
+    {
+      endRes = annotations.length - 1;
+    }
+    if (annotations == null)
+    {
+      return;
+    }
+    Annotation[] temp = new Annotation[endRes - startRes + 1];
+    if (startRes < annotations.length)
+    {
+      System.arraycopy(annotations, startRes, temp, 0,
+              endRes - startRes + 1);
+    }
+    if (sequenceRef != null)
+    {
+      // Clip the mapping, if it exists.
+      int spos = sequenceRef.findPosition(startRes);
+      int epos = sequenceRef.findPosition(endRes);
+      if (sequenceMapping != null)
+      {
+        Map<Integer, Annotation> newmapping = new HashMap<>();
+        Iterator<Integer> e = sequenceMapping.keySet().iterator();
+        while (e.hasNext())
+        {
+          Integer pos = e.next();
+          if (pos.intValue() >= spos && pos.intValue() <= epos)
+          {
+            newmapping.put(pos, sequenceMapping.get(pos));
+          }
+        }
+        sequenceMapping.clear();
+        sequenceMapping = newmapping;
+      }
+    }
+    annotations = temp;
+  }
+
+  /**
+   * set the annotation row to be at least length Annotations
+   * 
+   * @param length
+   *          minimum number of columns required in the annotation row
+   * @return false if the annotation row is greater than length
+   */
+  public boolean padAnnotation(int length)
+  {
+    if (annotations == null)
+    {
+      return true; // annotation row is correct - null == not visible and
+      // undefined length
+    }
+    if (annotations.length < length)
+    {
+      Annotation[] na = new Annotation[length];
+      System.arraycopy(annotations, 0, na, 0, annotations.length);
+      annotations = na;
+      return true;
+    }
+    return annotations.length > length;
+
+  }
+
+  /**
+   * DOCUMENT ME!
+   * 
+   * @return DOCUMENT ME!
+   */
+  @Override
+  public String toString()
+  {
+    if (annotations == null)
+    {
+      return "";
+    }
+    StringBuilder buffer = new StringBuilder(256);
+
+    for (int i = 0; i < annotations.length; i++)
+    {
+      if (annotations[i] != null)
+      {
+        if (graph != 0)
+        {
+          buffer.append(annotations[i].value);
+        }
+        else if (hasIcons)
+        {
+          buffer.append(annotations[i].secondaryStructure);
+        }
+        else
+        {
+          buffer.append(annotations[i].displayCharacter);
+        }
+      }
+
+      buffer.append(", ");
+    }
+    // TODO: remove disgusting hack for 'special' treatment of consensus line.
+    if (label.indexOf("Consensus") == 0)
+    {
+      buffer.append("\n");
+
+      for (int i = 0; i < annotations.length; i++)
+      {
+        if (annotations[i] != null)
+        {
+          buffer.append(annotations[i].description);
+        }
+
+        buffer.append(", ");
+      }
+    }
+
+    return buffer.toString();
+  }
+
+  public void setThreshold(GraphLine line)
+  {
+    threshold = line;
+  }
+
+  public GraphLine getThreshold()
+  {
+    return threshold;
+  }
+
+  /**
+   * Attach the annotation to seqRef, starting from startRes position. If
+   * alreadyMapped is true then the indices of the annotation[] array are
+   * sequence positions rather than alignment column positions.
+   * 
+   * @param seqRef
+   * @param startRes
+   * @param alreadyMapped
+   */
+  public void createSequenceMapping(SequenceI seqRef, int startRes,
+          boolean alreadyMapped)
+  {
+
+    if (seqRef == null)
+    {
+      return;
+    }
+    sequenceRef = seqRef;
+    if (annotations == null)
+    {
+      return;
+    }
+    sequenceMapping = new HashMap<>();
+
+    int seqPos;
+
+    for (int i = 0; i < annotations.length; i++)
+    {
+      if (annotations[i] != null)
+      {
+        if (alreadyMapped)
+        {
+          seqPos = seqRef.findPosition(i);
+        }
+        else
+        {
+          seqPos = i + startRes;
+        }
+
+        sequenceMapping.put(new Integer(seqPos), annotations[i]);
+      }
+    }
+
+  }
+
+  /**
+   * When positional annotation and a sequence reference is present, clears and
+   * resizes the annotations array to the current alignment width, and adds
+   * annotation according to aligned positions of the sequenceRef given by
+   * sequenceMapping.
+   */
+  public void adjustForAlignment()
+  {
+    if (sequenceRef == null)
+    {
+      return;
+    }
+
+    if (annotations == null)
+    {
+      return;
+    }
+
+    int a = 0, aSize = sequenceRef.getLength();
+
+    if (aSize == 0)
+    {
+      // Its been deleted
+      return;
+    }
+
+    int position;
+    Annotation[] temp = new Annotation[aSize];
+    Integer index;
+    if (sequenceMapping != null)
+    {
+      for (a = sequenceRef.getStart(); a <= sequenceRef.getEnd(); a++)
+      {
+        index = new Integer(a);
+        Annotation annot = sequenceMapping.get(index);
+        if (annot != null)
+        {
+          position = sequenceRef.findIndex(a) - 1;
+
+          temp[position] = annot;
+        }
+      }
+    }
+    annotations = temp;
+  }
+
+  /**
+   * remove any null entries in annotation row and return the number of non-null
+   * annotation elements.
+   * 
+   * @return
+   */
+  public int compactAnnotationArray()
+  {
+    int i = 0, iSize = annotations.length;
+    while (i < iSize)
+    {
+      if (annotations[i] == null)
+      {
+        if (i + 1 < iSize)
+        {
+          System.arraycopy(annotations, i + 1, annotations, i,
+                  iSize - i - 1);
+        }
+        iSize--;
+      }
+      else
+      {
+        i++;
+      }
+    }
+    Annotation[] ann = annotations;
+    annotations = new Annotation[i];
+    System.arraycopy(ann, 0, annotations, 0, i);
+    ann = null;
+    return iSize;
+  }
+
+  /**
+   * Associate this annotation with the aligned residues of a particular
+   * sequence. sequenceMapping will be updated in the following way: null
+   * sequenceI - existing mapping will be discarded but annotations left in
+   * mapped positions. valid sequenceI not equal to current sequenceRef: mapping
+   * is discarded and rebuilt assuming 1:1 correspondence TODO: overload with
+   * parameter to specify correspondence between current and new sequenceRef
+   * 
+   * @param sequenceI
+   */
+  public void setSequenceRef(SequenceI sequenceI)
+  {
+    if (sequenceI != null)
+    {
+      if (sequenceRef != null)
+      {
+        boolean rIsDs = sequenceRef.getDatasetSequence() == null,
+                tIsDs = sequenceI.getDatasetSequence() == null;
+        if (sequenceRef != sequenceI
+                && (rIsDs && !tIsDs
+                        && sequenceRef != sequenceI.getDatasetSequence())
+                && (!rIsDs && tIsDs
+                        && sequenceRef.getDatasetSequence() != sequenceI)
+                && (!rIsDs && !tIsDs
+                        && sequenceRef.getDatasetSequence() != sequenceI
+                                .getDatasetSequence())
+                && !sequenceRef.equals(sequenceI))
+        {
+          // if sequenceRef isn't intersecting with sequenceI
+          // throw away old mapping and reconstruct.
+          sequenceRef = null;
+          if (sequenceMapping != null)
+          {
+            sequenceMapping = null;
+            // compactAnnotationArray();
+          }
+          createSequenceMapping(sequenceI, 1, true);
+          adjustForAlignment();
+        }
+        else
+        {
+          // Mapping carried over
+          sequenceRef = sequenceI;
+        }
+      }
+      else
+      {
+        // No mapping exists
+        createSequenceMapping(sequenceI, 1, true);
+        adjustForAlignment();
+      }
+    }
+    else
+    {
+      // throw away the mapping without compacting.
+      sequenceMapping = null;
+      sequenceRef = null;
+    }
+  }
+
+  /**
+   * @return the score
+   */
+  public double getScore()
+  {
+    return score;
+  }
+
+  /**
+   * @param score
+   *          the score to set
+   */
+  public void setScore(double score)
+  {
+    hasScore = true;
+    this.score = score;
+  }
+
+  /**
+   * 
+   * @return true if annotation has an associated score
+   */
+  public boolean hasScore()
+  {
+    return hasScore || !Double.isNaN(score);
+  }
+
+  /**
+   * Score only annotation
+   * 
+   * @param label
+   * @param description
+   * @param score
+   */
+  public AlignmentAnnotation(String label, String description, double score)
+  {
+    this(label, description, null);
+    setScore(score);
+  }
+
+  /**
+   * copy constructor with edit based on the hidden columns marked in colSel
+   * 
+   * @param alignmentAnnotation
+   * @param colSel
+   */
+  public AlignmentAnnotation(AlignmentAnnotation alignmentAnnotation,
+          HiddenColumns hidden)
+  {
+    this(alignmentAnnotation);
+    if (annotations == null)
+    {
+      return;
+    }
+    makeVisibleAnnotation(hidden);
+  }
+
+  public void setPadGaps(boolean padgaps, char gapchar)
+  {
+    this.padGaps = padgaps;
+    if (padgaps)
+    {
+      hasText = true;
+      for (int i = 0; i < annotations.length; i++)
+      {
+        if (annotations[i] == null)
+        {
+          annotations[i] = new Annotation(String.valueOf(gapchar), null,
+                  ' ', 0f, null);
+        }
+        else if (annotations[i].displayCharacter == null
+                || annotations[i].displayCharacter.equals(" "))
+        {
+          annotations[i].displayCharacter = String.valueOf(gapchar);
+        }
+      }
+    }
+  }
+
+  /**
+   * format description string for display
+   * 
+   * @param seqname
+   * @return Get the annotation description string optionally prefixed by
+   *         associated sequence name (if any)
+   */
+  public String getDescription(boolean seqname)
+  {
+    if (seqname && this.sequenceRef != null)
+    {
+      int i = description.toLowerCase().indexOf("<html>");
+      if (i > -1)
+      {
+        // move the html tag to before the sequence reference.
+        return "<html>" + sequenceRef.getName() + " : "
+                + description.substring(i + 6);
+      }
+      return sequenceRef.getName() + " : " + description;
+    }
+    return description;
+  }
+
+  public boolean isValidStruc()
+  {
+    return invalidrnastruc == -1;
+  }
+
+  public long getInvalidStrucPos()
+  {
+    return invalidrnastruc;
+  }
+
+  /**
+   * machine readable ID string indicating what generated this annotation
+   */
+  protected String calcId = "";
+
+  /**
+   * properties associated with the calcId
+   */
+  protected Map<String, String> properties = new HashMap<>();
+
+  /**
+   * base colour for line graphs. If null, will be set automatically by
+   * searching the alignment annotation
+   */
+  public java.awt.Color _linecolour;
+
+  public String getCalcId()
+  {
+    return calcId;
+  }
+
+  public void setCalcId(String calcId)
+  {
+    this.calcId = calcId;
+  }
+
+  public boolean isRNA()
+  {
+    return isrna;
+  }
+
+  /**
+   * transfer annotation to the given sequence using the given mapping from the
+   * current positions or an existing sequence mapping
+   * 
+   * @param sq
+   * @param sp2sq
+   *          map involving sq as To or From
+   */
+  public void liftOver(SequenceI sq, Mapping sp2sq)
+  {
+    if (sp2sq.getMappedWidth() != sp2sq.getWidth())
+    {
+      // TODO: employ getWord/MappedWord to transfer annotation between cDNA and
+      // Protein reference frames
+      throw new Error(
+              "liftOver currently not implemented for transfer of annotation between different types of seqeunce");
+    }
+    boolean mapIsTo = (sp2sq != null)
+            ? (sp2sq.getTo() == sq
+                    || sp2sq.getTo() == sq.getDatasetSequence())
+            : false;
+
+    // TODO build a better annotation element map and get rid of annotations[]
+    Map<Integer, Annotation> mapForsq = new HashMap<>();
+    if (sequenceMapping != null)
+    {
+      if (sp2sq != null)
+      {
+       int[] reg = new int[MapList.LEN]; 
+        for (Entry<Integer, Annotation> ie : sequenceMapping.entrySet())
+        {
+          reg[MapList.POS] = ie.getKey();
+          int mpos = sp2sq.getPosition(reg, mapIsTo);
+          if (mpos >= sq.getStart() && mpos <= sq.getEnd())
+          {
+            mapForsq.put(mpos, ie.getValue());
+          }
+        }
+        sequenceMapping = mapForsq;
+        sequenceRef = sq;
+        adjustForAlignment();
+      }
+      else
+      {
+        // trim positions
+      }
+    }
+  }
+
+  /**
+   * like liftOver but more general.
+   * 
+   * Takes an array of int pairs that will be used to update the internal
+   * sequenceMapping and so shuffle the annotated positions
+   * 
+   * @param newref
+   *          - new sequence reference for the annotation row - if null,
+   *          sequenceRef is left unchanged
+   * @param mapping
+   *          array of ints containing corresponding positions
+   * @param from
+   *          - column for current coordinate system (-1 for index+1)
+   * @param to
+   *          - column for destination coordinate system (-1 for index+1)
+   * @param idxoffset
+   *          - offset added to index when referencing either coordinate system
+   * @note no checks are made as to whether from and/or to are sensible
+   * @note caller should add the remapped annotation to newref if they have not
+   *       already
+   */
+  public void remap(SequenceI newref, HashMap<Integer, int[]> mapping,
+          int from, int to, int idxoffset)
+  {
+    if (mapping != null)
+    {
+      Map<Integer, Annotation> old = sequenceMapping;
+      Map<Integer, Annotation> remap = new HashMap<>();
+      int index = -1;
+      for (int mp[] : mapping.values())
+      {
+        if (index++ < 0)
+        {
+          continue;
+        }
+        Annotation ann = null;
+        if (from == -1)
+        {
+          ann = sequenceMapping.get(Integer.valueOf(idxoffset + index));
+        }
+        else
+        {
+          if (mp != null && mp.length > from)
+          {
+            ann = sequenceMapping.get(Integer.valueOf(mp[from]));
+          }
+        }
+        if (ann != null)
+        {
+          if (to == -1)
+          {
+            remap.put(Integer.valueOf(idxoffset + index), ann);
+          }
+          else
+          {
+            if (to > -1 && to < mp.length)
+            {
+              remap.put(Integer.valueOf(mp[to]), ann);
+            }
+          }
+        }
+      }
+      sequenceMapping = remap;
+      old.clear();
+      if (newref != null)
+      {
+        sequenceRef = newref;
+      }
+      adjustForAlignment();
+    }
+  }
+
+  public String getProperty(String property)
+  {
+    if (properties == null)
+    {
+      return null;
+    }
+    return properties.get(property);
+  }
+
+  public void setProperty(String property, String value)
+  {
+    if (properties == null)
+    {
+      properties = new HashMap<>();
+    }
+    properties.put(property, value);
+  }
+
+  public boolean hasProperties()
+  {
+    return properties != null && properties.size() > 0;
+  }
+
+  public Collection<String> getProperties()
+  {
+    if (properties == null)
+    {
+      return Collections.emptyList();
+    }
+    return properties.keySet();
+  }
+
+  /**
+   * Returns the Annotation for the given sequence position (base 1) if any,
+   * else null
+   * 
+   * @param position
+   * @return
+   */
+  public Annotation getAnnotationForPosition(int position)
+  {
+    return sequenceMapping == null ? null : sequenceMapping.get(position);
+
+  }
+
+  /**
+   * Set the id to "ann" followed by a counter that increments so as to be
+   * unique for the lifetime of the JVM
+   */
+  protected final void setAnnotationId()
+  {
+    this.annotationId = ANNOTATION_ID_PREFIX + Long.toString(nextId());
+  }
+
+  /**
+   * Returns the match for the last unmatched opening RNA helix pair symbol
+   * preceding the given column, or '(' if nothing found to match.
+   * 
+   * @param column
+   * @return
+   */
+  public String getDefaultRnaHelixSymbol(int column)
+  {
+    String result = "(";
+    if (annotations == null)
+    {
+      return result;
+    }
+
+    /*
+     * for each preceding column, if it contains an open bracket, 
+     * count whether it is still unmatched at column, if so return its pair
+     * (likely faster than the fancy alternative using stacks)
+     */
+    for (int col = column - 1; col >= 0; col--)
+    {
+      Annotation annotation = annotations[col];
+      if (annotation == null)
+      {
+        continue;
+      }
+      String displayed = annotation.displayCharacter;
+      if (displayed == null || displayed.length() != 1)
+      {
+        continue;
+      }
+      char symbol = displayed.charAt(0);
+      if (!Rna.isOpeningParenthesis(symbol))
+      {
+        continue;
+      }
+
+      /*
+       * found an opening bracket symbol
+       * count (closing-opening) symbols of this type that follow it,
+       * up to and excluding the target column; if the count is less
+       * than 1, the opening bracket is unmatched, so return its match
+       */
+      String closer = String
+              .valueOf(Rna.getMatchingClosingParenthesis(symbol));
+      String opener = String.valueOf(symbol);
+      int count = 0;
+      for (int j = col + 1; j < column; j++)
+      {
+        if (annotations[j] != null)
+        {
+          String s = annotations[j].displayCharacter;
+          if (closer.equals(s))
+          {
+            count++;
+          }
+          else if (opener.equals(s))
+          {
+            count--;
+          }
+        }
+      }
+      if (count < 1)
+      {
+        return closer;
+      }
+    }
+    return result;
+  }
+
+  protected static synchronized long nextId()
+  {
+    return counter++;
+  }
+
+  /**
+   * 
+   * @return true for rows that have a range of values in their annotation set
+   */
+  public boolean isQuantitative()
+  {
+    return graphMin < graphMax;
+  }
+
+  /**
+   * delete any columns in alignmentAnnotation that are hidden (including
+   * sequence associated annotation).
+   * 
+   * @param hiddenColumns
+   *          the set of hidden columns
+   */
+  public void makeVisibleAnnotation(HiddenColumns hiddenColumns)
+  {
+    if (annotations != null)
+    {
+      makeVisibleAnnotation(0, annotations.length, hiddenColumns);
+    }
+  }
+
+  /**
+   * delete any columns in alignmentAnnotation that are hidden (including
+   * sequence associated annotation).
+   * 
+   * @param start
+   *          remove any annotation to the right of this column
+   * @param end
+   *          remove any annotation to the left of this column
+   * @param hiddenColumns
+   *          the set of hidden columns
+   */
+  public void makeVisibleAnnotation(int start, int end,
+          HiddenColumns hiddenColumns)
+  {
+    if (annotations != null)
+    {
+      if (hiddenColumns.hasHiddenColumns())
+      {
+        removeHiddenAnnotation(start, end, hiddenColumns);
+      }
+      else
+      {
+        restrict(start, end);
+      }
+    }
+  }
+
+  /**
+   * The actual implementation of deleting hidden annotation columns
+   * 
+   * @param start
+   *          remove any annotation to the right of this column
+   * @param end
+   *          remove any annotation to the left of this column
+   * @param hiddenColumns
+   *          the set of hidden columns
+   */
+  private void removeHiddenAnnotation(int start, int end,
+          HiddenColumns hiddenColumns)
+  {
+    // mangle the alignmentAnnotation annotation array
+    ArrayList<Annotation[]> annels = new ArrayList<>();
+    Annotation[] els = null;
+
+    int w = 0;
+
+    Iterator<int[]> blocks = hiddenColumns.getVisContigsIterator(start,
+            end + 1, false);
+
+    int copylength;
+    int annotationLength;
+    while (blocks.hasNext())
+    {
+      int[] block = blocks.next();
+      annotationLength = block[1] - block[0] + 1;
+
+      if (blocks.hasNext())
+      {
+        // copy just the visible segment of the annotation row
+        copylength = annotationLength;
+      }
+      else
+      {
+        if (annotationLength + block[0] <= annotations.length)
+        {
+          // copy just the visible segment of the annotation row
+          copylength = annotationLength;
+        }
+        else
+        {
+          // copy to the end of the annotation row
+          copylength = annotations.length - block[0];
+        }
+      }
+
+      els = new Annotation[annotationLength];
+      annels.add(els);
+      System.arraycopy(annotations, block[0], els, 0, copylength);
+      w += annotationLength;
+    }
+
+    if (w != 0)
+    {
+      annotations = new Annotation[w];
+
+      w = 0;
+      for (Annotation[] chnk : annels)
+      {
+        System.arraycopy(chnk, 0, annotations, w, chnk.length);
+        w += chnk.length;
+      }
+    }
+  }
+
+  public static Iterable<AlignmentAnnotation> findAnnotations(
+          Iterable<AlignmentAnnotation> list, SequenceI seq, String calcId,
+          String label)
+  {
+
+    ArrayList<AlignmentAnnotation> aa = new ArrayList<>();
+    for (AlignmentAnnotation ann : list)
+    {
+      if ((calcId == null || (ann.getCalcId() != null
+              && ann.getCalcId().equals(calcId)))
+              && (seq == null || (ann.sequenceRef != null
+                      && ann.sequenceRef == seq))
+              && (label == null
+                      || (ann.label != null && ann.label.equals(label))))
+      {
+        aa.add(ann);
+      }
+    }
+    return aa;
+  }
+
+  /**
+   * Answer true if any annotation matches the calcId passed in (if not null).
+   * 
+   * @param list
+   *          annotation to search
+   * @param calcId
+   * @return
+   */
+  public static boolean hasAnnotation(List<AlignmentAnnotation> list,
+          String calcId)
+  {
+
+    if (calcId != null && !"".equals(calcId))
+    {
+      for (AlignmentAnnotation a : list)
+      {
+        if (a.getCalcId() == calcId)
+        {
+          return true;
+        }
+      }
+    }
+    return false;
+  }
+
+  public static Iterable<AlignmentAnnotation> findAnnotation(
+          List<AlignmentAnnotation> list, String calcId)
+  {
+
+    List<AlignmentAnnotation> aa = new ArrayList<>();
+    if (calcId == null)
+    {
+      return aa;
+    }
+    for (AlignmentAnnotation a : list)
+    {
+
+      if (a.getCalcId() == calcId || (a.getCalcId() != null
+              && calcId != null && a.getCalcId().equals(calcId)))
+      {
+        aa.add(a);
+      }
+    }
+    return aa;
+  }
+
+}
diff --git a/unused/MapList.java b/unused/MapList.java
new file mode 100644 (file)
index 0000000..a5aa8fd
--- /dev/null
@@ -0,0 +1,1286 @@
+/*
+ * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
+ * Copyright (C) $$Year-Rel$$ The Jalview Authors
+ * 
+ * This file is part of Jalview.
+ * 
+ * Jalview is free software: you can redistribute it and/or
+ * modify it under the terms of the GNU General Public License 
+ * as published by the Free Software Foundation, either version 3
+ * of the License, or (at your option) any later version.
+ *  
+ * Jalview is distributed in the hope that it will be useful, but 
+ * WITHOUT ANY WARRANTY; without even the implied warranty 
+ * of MERCHANTABILITY or FITNESS FOR A PARTICULAR 
+ * PURPOSE.  See the GNU General Public License for more details.
+ * 
+ * You should have received a copy of the GNU General Public License
+ * along with Jalview.  If not, see <http://www.gnu.org/licenses/>.
+ * The Jalview Authors are detailed in the 'AUTHORS' file.
+ */
+package jalview.util;
+
+import java.util.ArrayList;
+import java.util.Arrays;
+import java.util.List;
+
+/**
+ * A simple way of bijectively mapping a non-contiguous linear range to another
+ * non-contiguous linear range.
+ * 
+ * Use at your own risk!
+ * 
+ * TODO: efficient implementation of private posMap method
+ * 
+ * TODO: test/ensure that sense of from and to ratio start position is conserved
+ * (codon start position recovery)
+ */
+public class MapList
+{
+       
+  public static final int POS             = 0;
+  public static final int POS_FROM        = 1; // for countPos
+  public static final int DIR_FROM        = 2; // for countPos
+  public static final int POS_TO          = 3; // for countToPos
+  public static final int DIR_TO          = 4; // for countToPos
+  private static final int FROM_REMAINDER = 5;
+  public static final int LEN             = 6;
+/*
+   * Subregions (base 1) described as { [start1, end1], [start2, end2], ...}
+   */
+  private List<int[]> fromShifts;
+
+  /*
+   * Same format as fromShifts, for the 'mapped to' sequence
+   */
+  private List<int[]> toShifts;
+
+  /*
+   * number of steps in fromShifts to one toRatio unit
+   */
+  private int fromRatio;
+
+  /*
+   * number of steps in toShifts to one fromRatio
+   */
+  private int toRatio;
+
+  /*
+   * lowest and highest value in the from Map
+   */
+  private int fromLowest;
+
+  private int fromHighest;
+
+  /*
+   * lowest and highest value in the to Map
+   */
+  private int toLowest;
+
+  private int toHighest;
+
+  /**
+   * Constructor
+   */
+  public MapList()
+  {
+    fromShifts = new ArrayList<>();
+    toShifts = new ArrayList<>();
+  }
+
+  /**
+   * Two MapList objects are equal if they are the same object, or they both
+   * have populated shift ranges and all values are the same.
+   */
+  @Override
+  public boolean equals(Object o)
+  {
+    if (o == null || !(o instanceof MapList))
+    {
+      return false;
+    }
+
+    MapList obj = (MapList) o;
+    if (obj == this)
+    {
+      return true;
+    }
+    if (obj.fromRatio != fromRatio || obj.toRatio != toRatio
+            || obj.fromShifts == null || obj.toShifts == null)
+    {
+      return false;
+    }
+    return Arrays.deepEquals(fromShifts.toArray(), obj.fromShifts.toArray())
+            && Arrays.deepEquals(toShifts.toArray(),
+                    obj.toShifts.toArray());
+  }
+
+  /**
+   * Returns a hashcode made from the fromRatio, toRatio, and from/to ranges
+   */
+  @Override
+  public int hashCode()
+  {
+    int hashCode = 31 * fromRatio;
+    hashCode = 31 * hashCode + toRatio;
+    for (int[] shift : fromShifts)
+    {
+      hashCode = 31 * hashCode + shift[0];
+      hashCode = 31 * hashCode + shift[1];
+    }
+    for (int[] shift : toShifts)
+    {
+      hashCode = 31 * hashCode + shift[0];
+      hashCode = 31 * hashCode + shift[1];
+    }
+
+    return hashCode;
+  }
+
+  /**
+   * Returns the 'from' ranges as {[start1, end1], [start2, end2], ...}
+   * 
+   * @return
+   */
+  public List<int[]> getFromRanges()
+  {
+    return fromShifts;
+  }
+
+  /**
+   * Returns the 'to' ranges as {[start1, end1], [start2, end2], ...}
+   * 
+   * @return
+   */
+  public List<int[]> getToRanges()
+  {
+    return toShifts;
+  }
+
+  /**
+   * Flattens a list of [start, end] into a single [start1, end1, start2,
+   * end2,...] array.
+   * 
+   * @param shifts
+   * @return
+   */
+  protected static int[] getRanges(List<int[]> shifts)
+  {
+    int[] rnges = new int[2 * shifts.size()];
+    int i = 0;
+    for (int[] r : shifts)
+    {
+      rnges[i++] = r[0];
+      rnges[i++] = r[1];
+    }
+    return rnges;
+  }
+
+  /**
+   * 
+   * @return length of mapped phrase in from
+   */
+  public int getFromRatio()
+  {
+    return fromRatio;
+  }
+
+  /**
+   * 
+   * @return length of mapped phrase in to
+   */
+  public int getToRatio()
+  {
+    return toRatio;
+  }
+
+  public int getFromLowest()
+  {
+    return fromLowest;
+  }
+
+  public int getFromHighest()
+  {
+    return fromHighest;
+  }
+
+  public int getToLowest()
+  {
+    return toLowest;
+  }
+
+  public int getToHighest()
+  {
+    return toHighest;
+  }
+
+  /**
+   * Constructor given from and to ranges as [start1, end1, start2, end2,...].
+   * If any end is equal to the next start, the ranges will be merged. There is
+   * no validation check that the ranges do not overlap each other.
+   * 
+   * @param from
+   *          contiguous regions as [start1, end1, start2, end2, ...]
+   * @param to
+   *          same format as 'from'
+   * @param fromRatio
+   *          phrase length in 'from' (e.g. 3 for dna)
+   * @param toRatio
+   *          phrase length in 'to' (e.g. 1 for protein)
+   */
+  public MapList(int from[], int to[], int fromRatio, int toRatio)
+  {
+    this();
+    this.fromRatio = fromRatio;
+    this.toRatio = toRatio;
+    fromLowest = Integer.MAX_VALUE;
+    fromHighest = Integer.MIN_VALUE;
+    int added = 0;
+
+    for (int i = 0; i < from.length; i += 2)
+    {
+      /*
+       * note lowest and highest values - bearing in mind the
+       * direction may be reversed
+       */
+      fromLowest = Math.min(fromLowest, Math.min(from[i], from[i + 1]));
+      fromHighest = Math.max(fromHighest, Math.max(from[i], from[i + 1]));
+      if (added > 0 && from[i] == fromShifts.get(added - 1)[1])
+      {
+        /*
+         * this range starts where the last ended - just extend it
+         */
+        fromShifts.get(added - 1)[1] = from[i + 1];
+      }
+      else
+      {
+        fromShifts.add(new int[] { from[i], from[i + 1] });
+        added++;
+      }
+    }
+
+    toLowest = Integer.MAX_VALUE;
+    toHighest = Integer.MIN_VALUE;
+    added = 0;
+    for (int i = 0; i < to.length; i += 2)
+    {
+      toLowest = Math.min(toLowest, Math.min(to[i], to[i + 1]));
+      toHighest = Math.max(toHighest, Math.max(to[i], to[i + 1]));
+      if (added > 0 && to[i] == toShifts.get(added - 1)[1])
+      {
+        toShifts.get(added - 1)[1] = to[i + 1];
+      }
+      else
+      {
+        toShifts.add(new int[] { to[i], to[i + 1] });
+        added++;
+      }
+    }
+  }
+
+  /**
+   * Copy constructor. Creates an identical mapping.
+   * 
+   * @param map
+   */
+  public MapList(MapList map)
+  {
+    this();
+    // TODO not used - remove?
+    this.fromLowest = map.fromLowest;
+    this.fromHighest = map.fromHighest;
+    this.toLowest = map.toLowest;
+    this.toHighest = map.toHighest;
+
+    this.fromRatio = map.fromRatio;
+    this.toRatio = map.toRatio;
+    if (map.fromShifts != null)
+    {
+      for (int[] r : map.fromShifts)
+      {
+        fromShifts.add(new int[] { r[0], r[1] });
+      }
+    }
+    if (map.toShifts != null)
+    {
+      for (int[] r : map.toShifts)
+      {
+        toShifts.add(new int[] { r[0], r[1] });
+      }
+    }
+  }
+
+  /**
+   * Constructor given ranges as lists of [start, end] positions. There is no
+   * validation check that the ranges do not overlap each other.
+   * 
+   * @param fromRange
+   * @param toRange
+   * @param fromRatio
+   * @param toRatio
+   */
+  public MapList(List<int[]> fromRange, List<int[]> toRange, int fromRatio,
+          int toRatio)
+  {
+    this();
+    fromRange = coalesceRanges(fromRange);
+    toRange = coalesceRanges(toRange);
+    this.fromShifts = fromRange;
+    this.toShifts = toRange;
+    this.fromRatio = fromRatio;
+    this.toRatio = toRatio;
+
+    fromLowest = Integer.MAX_VALUE;
+    fromHighest = Integer.MIN_VALUE;
+    for (int[] range : fromRange)
+    {
+      if (range.length != 2)
+      {
+        // throw new IllegalArgumentException(range);
+        System.err.println(
+                "Invalid format for fromRange " + Arrays.toString(range)
+                + " may cause errors");
+      }
+      fromLowest = Math.min(fromLowest, Math.min(range[0], range[1]));
+      fromHighest = Math.max(fromHighest, Math.max(range[0], range[1]));
+    }
+
+    toLowest = Integer.MAX_VALUE;
+    toHighest = Integer.MIN_VALUE;
+    for (int[] range : toRange)
+    {
+      if (range.length != 2)
+      {
+        // throw new IllegalArgumentException(range);
+        System.err.println("Invalid format for toRange "
+                + Arrays.toString(range)
+                + " may cause errors");
+      }
+      toLowest = Math.min(toLowest, Math.min(range[0], range[1]));
+      toHighest = Math.max(toHighest, Math.max(range[0], range[1]));
+    }
+  }
+
+  /**
+   * Consolidates a list of ranges so that any contiguous ranges are merged.
+   * This assumes the ranges are already in start order (does not sort them).
+   * 
+   * @param ranges
+   * @return the same list (if unchanged), else a new merged list, leaving the
+   *         input list unchanged
+   */
+  public static List<int[]> coalesceRanges(final List<int[]> ranges)
+  {
+    if (ranges == null || ranges.size() < 2)
+    {
+      return ranges;
+    }
+
+    boolean changed = false;
+    List<int[]> merged = new ArrayList<>();
+    int[] lastRange = ranges.get(0);
+    int lastDirection = lastRange[1] >= lastRange[0] ? 1 : -1;
+    lastRange = new int[] { lastRange[0], lastRange[1] };
+    merged.add(lastRange);
+    boolean first = true;
+
+    for (final int[] range : ranges)
+    {
+      if (first)
+      {
+        first = false;
+        continue;
+      }
+      if (range[0] == lastRange[0] && range[1] == lastRange[1])
+      {
+        // drop duplicate range
+        changed = true;
+        continue;
+      }
+
+      /*
+       * drop this range if it lies within the last range
+       */
+      if ((lastDirection == 1 && range[0] >= lastRange[0]
+              && range[0] <= lastRange[1] && range[1] >= lastRange[0]
+              && range[1] <= lastRange[1])
+              || (lastDirection == -1 && range[0] <= lastRange[0]
+                      && range[0] >= lastRange[1]
+                      && range[1] <= lastRange[0]
+                      && range[1] >= lastRange[1]))
+      {
+        changed = true;
+        continue;
+      }
+
+      int direction = range[1] >= range[0] ? 1 : -1;
+
+      /*
+       * if next range is in the same direction as last and contiguous,
+       * just update the end position of the last range
+       */
+      boolean sameDirection = range[1] == range[0]
+              || direction == lastDirection;
+      boolean extending = range[0] == lastRange[1] + lastDirection;
+      boolean overlapping = (lastDirection == 1 && range[0] >= lastRange[0]
+              && range[0] <= lastRange[1])
+              || (lastDirection == -1 && range[0] <= lastRange[0]
+                      && range[0] >= lastRange[1]);
+      if (sameDirection && (overlapping || extending))
+      {
+        lastRange[1] = range[1];
+        changed = true;
+      }
+      else
+      {
+        lastRange = new int[] { range[0], range[1] };
+        merged.add(lastRange);
+        // careful: merging [5, 5] after [7, 6] should keep negative direction
+        lastDirection = (range[1] == range[0]) ? lastDirection : direction;
+      }
+    }
+
+    return changed ? merged : ranges;
+  }
+
+//  /**
+//   * get all mapped positions from 'from' to 'to'
+//   * 
+//   * @return int[][] { int[] { fromStart, fromFinish, toStart, toFinish }, int
+//   *         [fromFinish-fromStart+2] { toStart..toFinish mappings}}
+//   */
+//  protected int[][] makeFromMap()
+//  {
+//    // TODO not used - remove??
+//    return posMap(fromShifts, fromRatio, toShifts, toRatio);
+//  }
+//
+//  /**
+//   * get all mapped positions from 'to' to 'from'
+//   * 
+//   * @return int[to position]=position mapped in from
+//   */
+//  protected int[][] makeToMap()
+//  {
+//    // TODO not used - remove??
+//    return posMap(toShifts, toRatio, fromShifts, fromRatio);
+//  }
+
+//  /**
+//   * construct an int map for intervals in intVals
+//   * 
+//   * @param shiftTo
+//   * @return int[] { from, to pos in range }, int[range.to-range.from+1]
+//   *         returning mapped position
+//   */
+//  private int[][] posMap(List<int[]> shiftTo, int ratio,
+//          List<int[]> shiftFrom, int toRatio)
+//  {
+//    // TODO not used - remove??
+//       
+//     int[] reg = new int[LEN];  
+//       
+//    int iv = 0, ivSize = shiftTo.size();
+//    if (iv >= ivSize)
+//    {
+//      return null;
+//    }
+//    int[] intv = shiftTo.get(iv++);
+//    int from = intv[0], to = intv[1];
+//    if (from > to)
+//    {
+//      from = intv[1];
+//      to = intv[0];
+//    }
+//    while (iv < ivSize)
+//    {
+//      intv = shiftTo.get(iv++);
+//      if (intv[0] < from)
+//      {
+//        from = intv[0];
+//      }
+//      if (intv[1] < from)
+//      {
+//        from = intv[1];
+//      }
+//      if (intv[0] > to)
+//      {
+//        to = intv[0];
+//      }
+//      if (intv[1] > to)
+//      {
+//        to = intv[1];
+//      }
+//    }
+//    int tF = 0, tT = 0;
+//    int mp[][] = new int[to - from + 2][];
+//    for (int i = 0; i < mp.length; i++)
+//    {
+//     reg[POS] = i + from;
+//      int[] m = shift(reg, shiftTo, ratio, shiftFrom, toRatio);
+//      if (m != null)
+//      {
+//        if (i == 0)
+//        {
+//          tF = tT = m[0];
+//        }
+//        else
+//        {
+//          if (m[0] < tF)
+//          {
+//            tF = m[0];
+//          }
+//          if (m[0] > tT)
+//          {
+//            tT = m[0];
+//          }
+//        }
+//      }
+//      mp[i] = m;
+//    }
+//    int[][] map = new int[][] { new int[] { from, to, tF, tT },
+//        new int[to - from + 2] };
+//
+//    map[0][2] = tF;
+//    map[0][3] = tT;
+//
+//    for (int i = 0; i < mp.length; i++)
+//    {
+//      if (mp[i] != null)
+//      {
+//        map[1][i] = mp[i][0] - tF;
+//      }
+//      else
+//      {
+//        map[1][i] = -1; // indicates an out of range mapping
+//      }
+//    }
+//    return map;
+//  }
+
+  /**
+   * addShift
+   * 
+   * @param pos
+   *          start position for shift (in original reference frame)
+   * @param shift
+   *          length of shift
+   * 
+   *          public void addShift(int pos, int shift) { int sidx = 0; int[]
+   *          rshift=null; while (sidx<shifts.size() && (rshift=(int[])
+   *          shifts.elementAt(sidx))[0]<pos) sidx++; if (sidx==shifts.size())
+   *          shifts.insertElementAt(new int[] { pos, shift}, sidx); else
+   *          rshift[1]+=shift; }
+   */
+
+  /**
+   * shift from pos to To(pos)
+   * 
+   * @param reg[POS]
+   *         
+   * @return int[] reg[POS_TO:shifted position in To, 
+   *                   FROM_REMAINDER: frameshift in From, 
+   *                   DIR_TO: direction of mapped symbol in To]
+   */
+  public int[] shiftFrom(int[] reg)
+  {
+    return shift(reg, fromShifts, fromRatio, toShifts, toRatio);
+  }
+
+  /**
+   * inverse of shiftFrom - maps pos in To to a position in From
+   * 
+   * @param pos
+   *          (in To)
+   * @return shifted position in From, frameshift in To, direction of mapped
+   *         symbol in From
+   */
+  public int[] shiftTo(int[] reg)
+  {
+    return shift(reg, toShifts, toRatio, fromShifts, fromRatio);
+  }
+
+  /**
+   * 
+   * @param reg[POS]
+   * @param shiftTo
+   * @param fromRatio
+   * @param shiftFrom
+   * @param toRatio
+   * @return  reg[COUNT_TO, FROM_REMAINDER, DIR_TO]
+   */
+  protected static int[] shift(int[] reg, List<int[]> shiftTo, int fromRatio,
+          List<int[]> shiftFrom, int toRatio)
+  {
+    // TODO: javadoc; tests
+    reg = countPos(shiftTo, reg);
+    if (reg == null)
+    {
+      return null;
+    }
+    reg[FROM_REMAINDER] = (reg[POS_FROM] - 1) % fromRatio;
+    reg[POS] = 1 + (((reg[POS_FROM] - 1) / fromRatio) * toRatio); // toCount
+    reg = countToPos(shiftFrom, reg);
+    if (reg == null)
+    {
+      return null; // throw new Error("Bad Mapping!");
+    }
+    // reg is now filled
+    // System.out.println(fromCount[0]+" "+fromCount[1]+" "+toCount);
+//    ret3[0] = toPos[0];
+//    ret3[1] = fromRemainder;
+//    ret3[2] = toPos[1];
+    return reg;
+  }
+
+  /**
+   * count how many positions pos is along the series of intervals.
+   * 
+   * @param shiftTo
+   * @param pos
+   * @return number of positions or null if pos is not within intervals
+   */
+  protected static int[] countPos(List<int[]> shiftTo, int[] reg)
+  {
+       int pos = reg[POS];
+    int count = 0, iv = 0, ivSize = shiftTo.size();
+    while (iv < ivSize)
+    {
+      int[] intv = shiftTo.get(iv++);
+      if (intv[0] <= intv[1])
+      {
+        if (pos >= intv[0] && pos <= intv[1])
+        {
+               reg[POS_FROM] = count + pos - intv[0] + 1;
+               reg[DIR_FROM] = 1;
+               return reg;
+        }
+        else
+        {
+          count += intv[1] - intv[0] + 1;
+        }
+      }
+      else
+      {
+        if (pos >= intv[1] && pos <= intv[0])
+        {
+               reg[POS_FROM] = count - pos + intv[0] + 1;
+               reg[DIR_FROM] = -1;
+               return reg;
+        }
+        else
+        {
+          count += intv[0] - intv[1] + 1;
+        }
+      }
+    }
+    return null;
+  }
+
+  /**
+   * count out pos positions into a series of intervals and return the position
+   * 
+   * @param shiftFrom
+   * @param pos
+   * @return position pos in interval set
+   */
+  protected static int[] countToPos(List<int[]> shiftFrom, int[] reg)
+  {
+    int count = 0, diff = 0, iv = 0, ivSize = shiftFrom.size();
+    int pos = reg[POS];
+    while (iv < ivSize)
+    {
+      int[] intv = shiftFrom.get(iv++);
+      diff = intv[1] - intv[0];
+      if (diff >= 0)
+      {
+        if (pos <= count + 1 + diff)
+        {
+          reg[POS_TO] = intv[0] + pos - count - 1;
+          reg[DIR_TO] = 1;
+          return reg;
+        }
+        else
+        {
+          count += 1 + diff;
+        }
+      }
+      else
+      {
+        if (pos <= count + 1 - diff)
+        {
+            reg[POS_TO] = intv[0] - (pos - count - 1);
+            reg[DIR_TO] = -1;
+            return reg;
+        }
+        else
+        {
+          count += 1 - diff;
+        }
+      }
+    }
+    return null;// (diff<0) ? (intv[1]-1) : (intv[0]+1);
+  }
+
+  /**
+   * find series of intervals mapping from start-end in the From map.
+   * 
+   * @param start
+   *          position mapped 'to'
+   * @param end
+   *          position mapped 'to'
+   * @return series of [start, end] ranges in sequence mapped 'from'
+   */
+  public int[] locateInFrom(int start, int end)
+  {
+       int[] reg = new int[LEN];
+    // inefficient implementation
+       reg[POS] = start;
+    reg = shiftTo(reg);
+    if (reg == null)
+       return null;
+    // needs to be inclusive of end of symbol position
+    start = reg[POS_TO];
+    reg[POS] = end;
+    reg = shiftTo(reg);
+    if (reg == null)
+       return null;
+    end = reg[POS_TO];    
+    return getIntervals(fromShifts, start, end, fromRatio);
+  }
+
+  /**
+   * find series of intervals mapping from start-end in the to map.
+   * 
+   * @param start
+   *          position mapped 'from'
+   * @param end
+   *          position mapped 'from'
+   * @return series of [start, end] ranges in sequence mapped 'to'
+   */
+  public int[] locateInTo(int start, int end)
+  {
+       int[] reg = new int[LEN];
+       reg[POS] = start;
+    reg = shiftFrom(reg);
+    if (reg == null)
+       return null;
+    start = reg[POS_FROM];
+       reg[POS] = end;
+       reg = shiftFrom(reg);
+    if (reg == null)
+       return null;
+    end = reg[POS_FROM];
+    return getIntervals(toShifts, start, end, toRatio);
+  }
+
+  /**
+   * like shift - except returns the intervals in the given vector of shifts
+   * which were spanned in traversing fromStart to fromEnd
+   * 
+   * @param shiftFrom
+   * @param fromStart
+   * @param fromEnd
+   * @param fromRatio2
+   * @return series of from,to intervals from from first position of starting
+   *         region to final position of ending region inclusive
+   */
+  protected static int[] getIntervals(List<int[]> shiftFrom,
+          int startpos, int endpos, int fromRatio2)
+  {
+//    if (fromStart == null || fromEnd == null)
+//    {
+//      return null;
+//    }
+//    int startpos, endpos;
+//    startpos = fromStart[0]; // first position in fromStart
+//    endpos = fromEnd[0]; // last position in fromEnd
+    int endindx = (fromRatio2 - 1); // additional positions to get to last
+    // position from endpos
+    int intv = 0, intvSize = shiftFrom.size();
+    int iv[], i = 0, fs = -1, fe_s = -1, fe = -1; // containing intervals
+    // search intervals to locate ones containing startpos and count endindx
+    // positions on from endpos
+    while (intv < intvSize && (fs == -1 || fe == -1))
+    {
+      iv = shiftFrom.get(intv++);
+      if (fe_s > -1)
+      {
+        endpos = iv[0]; // start counting from beginning of interval
+        endindx--; // inclusive of endpos
+      }
+      if (iv[0] <= iv[1])
+      {
+        if (fs == -1 && startpos >= iv[0] && startpos <= iv[1])
+        {
+          fs = i;
+        }
+        if (endpos >= iv[0] && endpos <= iv[1])
+        {
+          if (fe_s == -1)
+          {
+            fe_s = i;
+          }
+          if (fe_s != -1)
+          {
+            if (endpos + endindx <= iv[1])
+            {
+              fe = i;
+              endpos = endpos + endindx; // end of end token is within this
+              // interval
+            }
+            else
+            {
+              endindx -= iv[1] - endpos; // skip all this interval too
+            }
+          }
+        }
+      }
+      else
+      {
+        if (fs == -1 && startpos <= iv[0] && startpos >= iv[1])
+        {
+          fs = i;
+        }
+        if (endpos <= iv[0] && endpos >= iv[1])
+        {
+          if (fe_s == -1)
+          {
+            fe_s = i;
+          }
+          if (fe_s != -1)
+          {
+            if (endpos - endindx >= iv[1])
+            {
+              fe = i;
+              endpos = endpos - endindx; // end of end token is within this
+              // interval
+            }
+            else
+            {
+              endindx -= endpos - iv[1]; // skip all this interval too
+            }
+          }
+        }
+      }
+      i++;
+    }
+    if (fs == fe && fe == -1)
+    {
+      return null;
+    }
+    List<int[]> ranges = new ArrayList<>();
+    if (fs <= fe)
+    {
+      intv = fs;
+      i = fs;
+      // truncate initial interval
+      iv = shiftFrom.get(intv++);
+      iv = new int[] { iv[0], iv[1] };// clone
+      if (i == fs)
+      {
+        iv[0] = startpos;
+      }
+      while (i != fe)
+      {
+        ranges.add(iv); // add initial range
+        iv = shiftFrom.get(intv++); // get next interval
+        iv = new int[] { iv[0], iv[1] };// clone
+        i++;
+      }
+      if (i == fe)
+      {
+        iv[1] = endpos;
+      }
+      ranges.add(iv); // add only - or final range
+    }
+    else
+    {
+      // walk from end of interval.
+      i = shiftFrom.size() - 1;
+      while (i > fs)
+      {
+        i--;
+      }
+      iv = shiftFrom.get(i);
+      iv = new int[] { iv[1], iv[0] };// reverse and clone
+      // truncate initial interval
+      if (i == fs)
+      {
+        iv[0] = startpos;
+      }
+      while (--i != fe)
+      { // fix apparent logic bug when fe==-1
+        ranges.add(iv); // add (truncated) reversed interval
+        iv = shiftFrom.get(i);
+        iv = new int[] { iv[1], iv[0] }; // reverse and clone
+      }
+      if (i == fe)
+      {
+        // interval is already reversed
+        iv[1] = endpos;
+      }
+      ranges.add(iv); // add only - or final range
+    }
+    // create array of start end intervals.
+    int[] range = null;
+    if (ranges != null && ranges.size() > 0)
+    {
+      range = new int[ranges.size() * 2];
+      intv = 0;
+      intvSize = ranges.size();
+      i = 0;
+      while (intv < intvSize)
+      {
+        iv = ranges.get(intv);
+        range[i++] = iv[0];
+        range[i++] = iv[1];
+        ranges.set(intv++, null); // remove
+      }
+    }
+    return range;
+  }
+
+//  /**
+//   * get the 'initial' position of mpos in To
+//   * 
+//   * @param mpos
+//   *          position in from
+//   * @return position of first word in to reference frame
+//   */
+//  public int getToPosition(int[])
+//  {
+//    // TODO not used - remove??
+//    int[] mp = shiftTo(mpos);
+//    if (mp != null)
+//    {
+//      return mp[0];
+//    }
+//    return mpos;
+//  }
+//
+//  /**
+//   * get range of positions in To frame for the mpos word in From
+//   * 
+//   * @param mpos
+//   *          position in From
+//   * @return null or int[] first position in To for mpos, last position in to
+//   *         for Mpos
+//   */
+//  public int[] getToWord(int mpos)
+//  {
+//       // never called
+//    int[] mp = shiftTo(mpos);
+//    if (mp != null)
+//    {
+//      return new int[] { mp[0], mp[0] + mp[2] * (getFromRatio() - 1) };
+//    }
+//    return null;
+//  }
+
+  /**
+   * get From position in the associated reference frame for position pos in the
+   * associated sequence.
+   * 
+   * @param pos
+   * @return
+   */
+  public int getMappedPosition(int[] reg)
+  {
+    // TODO not used - remove??
+       int pos = reg[POS];
+    reg = shiftFrom(reg);
+    if (reg != null)
+    {
+      return reg[POS_TO];
+    }
+    return pos;
+  }
+
+//  public int[] getMappedWord(int[] reg)
+//  {
+//    // TODO not used - remove??
+//    reg = shiftFrom(reg);
+//    if (reg != null)
+//    {
+//      return new int[] { mp[0], mp[0] + mp[2] * (getToRatio() - 1) };
+//    }
+//    return null;
+//  }
+
+  /**
+   * 
+   * @return a MapList whose From range is this maplist's To Range, and vice
+   *         versa
+   */
+  public MapList getInverse()
+  {
+    return new MapList(getToRanges(), getFromRanges(), getToRatio(),
+            getFromRatio());
+  }
+
+  /**
+   * test for containment rather than equivalence to another mapping
+   * 
+   * @param map
+   *          to be tested for containment
+   * @return true if local or mapped range map contains or is contained by this
+   *         mapping
+   */
+  public boolean containsEither(boolean local, MapList map)
+  {
+    // TODO not used - remove?
+    if (local)
+    {
+      return ((getFromLowest() >= map.getFromLowest()
+              && getFromHighest() <= map.getFromHighest())
+              || (getFromLowest() <= map.getFromLowest()
+                      && getFromHighest() >= map.getFromHighest()));
+    }
+    else
+    {
+      return ((getToLowest() >= map.getToLowest()
+              && getToHighest() <= map.getToHighest())
+              || (getToLowest() <= map.getToLowest()
+                      && getToHighest() >= map.getToHighest()));
+    }
+  }
+
+  /**
+   * String representation - for debugging, not guaranteed not to change
+   */
+  @Override
+  public String toString()
+  {
+    StringBuilder sb = new StringBuilder(64);
+    sb.append("[");
+    for (int[] shift : fromShifts)
+    {
+      sb.append(" ").append(Arrays.toString(shift));
+    }
+    sb.append(" ] ");
+    sb.append(fromRatio).append(":").append(toRatio);
+    sb.append(" to [");
+    for (int[] shift : toShifts)
+    {
+      sb.append(" ").append(Arrays.toString(shift));
+    }
+    sb.append(" ]");
+    return sb.toString();
+  }
+
+  /**
+   * Extend this map list by adding the given map's ranges. There is no
+   * validation check that the ranges do not overlap existing ranges (or each
+   * other), but contiguous ranges are merged.
+   * 
+   * @param map
+   */
+  public void addMapList(MapList map)
+  {
+    if (this.equals(map))
+    {
+      return;
+    }
+    this.fromLowest = Math.min(fromLowest, map.fromLowest);
+    this.toLowest = Math.min(toLowest, map.toLowest);
+    this.fromHighest = Math.max(fromHighest, map.fromHighest);
+    this.toHighest = Math.max(toHighest, map.toHighest);
+
+    for (int[] range : map.getFromRanges())
+    {
+      addRange(range, fromShifts);
+    }
+    for (int[] range : map.getToRanges())
+    {
+      addRange(range, toShifts);
+    }
+  }
+
+  /**
+   * Adds the given range to a list of ranges. If the new range just extends
+   * existing ranges, the current endpoint is updated instead.
+   * 
+   * @param range
+   * @param addTo
+   */
+  static void addRange(int[] range, List<int[]> addTo)
+  {
+    /*
+     * list is empty - add to it!
+     */
+    if (addTo.size() == 0)
+    {
+      addTo.add(range);
+      return;
+    }
+
+    int[] last = addTo.get(addTo.size() - 1);
+    boolean lastForward = last[1] >= last[0];
+    boolean newForward = range[1] >= range[0];
+
+    /*
+     * contiguous range in the same direction - just update endpoint
+     */
+    if (lastForward == newForward && last[1] == range[0])
+    {
+      last[1] = range[1];
+      return;
+    }
+
+    /*
+     * next range starts at +1 in forward sense - update endpoint
+     */
+    if (lastForward && newForward && range[0] == last[1] + 1)
+    {
+      last[1] = range[1];
+      return;
+    }
+
+    /*
+     * next range starts at -1 in reverse sense - update endpoint
+     */
+    if (!lastForward && !newForward && range[0] == last[1] - 1)
+    {
+      last[1] = range[1];
+      return;
+    }
+
+    /*
+     * just add the new range
+     */
+    addTo.add(range);
+  }
+
+  /**
+   * Returns true if mapping is from forward strand, false if from reverse
+   * strand. Result is just based on the first 'from' range that is not a single
+   * position. Default is true unless proven to be false. Behaviour is not well
+   * defined if the mapping has a mixture of forward and reverse ranges.
+   * 
+   * @return
+   */
+  public boolean isFromForwardStrand()
+  {
+    return isForwardStrand(getFromRanges());
+  }
+
+  /**
+   * Returns true if mapping is to forward strand, false if to reverse strand.
+   * Result is just based on the first 'to' range that is not a single position.
+   * Default is true unless proven to be false. Behaviour is not well defined if
+   * the mapping has a mixture of forward and reverse ranges.
+   * 
+   * @return
+   */
+  public boolean isToForwardStrand()
+  {
+    return isForwardStrand(getToRanges());
+  }
+
+  /**
+   * A helper method that returns true unless at least one range has start > end.
+   * Behaviour is undefined for a mixture of forward and reverse ranges.
+   * 
+   * @param ranges
+   * @return
+   */
+  private boolean isForwardStrand(List<int[]> ranges)
+  {
+    boolean forwardStrand = true;
+    for (int[] range : ranges)
+    {
+      if (range[1] > range[0])
+      {
+        break; // forward strand confirmed
+      }
+      else if (range[1] < range[0])
+      {
+        forwardStrand = false;
+        break; // reverse strand confirmed
+      }
+    }
+    return forwardStrand;
+  }
+
+  /**
+   * 
+   * @return true if from, or to is a three to 1 mapping
+   */
+  public boolean isTripletMap()
+  {
+    return (toRatio == 3 && fromRatio == 1)
+            || (fromRatio == 3 && toRatio == 1);
+  }
+
+  /**
+   * Returns a map which is the composite of this one and the input map. That
+   * is, the output map has the fromRanges of this map, and its toRanges are the
+   * toRanges of this map as transformed by the input map.
+   * <p>
+   * Returns null if the mappings cannot be traversed (not all toRanges of this
+   * map correspond to fromRanges of the input), or if this.toRatio does not
+   * match map.fromRatio.
+   * 
+   * <pre>
+   * Example 1:
+   *    this:   from [1-100] to [501-600]
+   *    input:  from [10-40] to [60-90]
+   *    output: from [10-40] to [560-590]
+   * Example 2 ('reverse strand exons'):
+   *    this:   from [1-100] to [2000-1951], [1000-951] // transcript to loci
+   *    input:  from [1-50]  to [41-90] // CDS to transcript
+   *    output: from [10-40] to [1960-1951], [1000-971] // CDS to gene loci
+   * </pre>
+   * 
+   * @param map
+   * @return
+   */
+  public MapList traverse(MapList map)
+  {
+    if (map == null)
+    {
+      return null;
+    }
+
+    /*
+     * compound the ratios by this rule:
+     * A:B with M:N gives A*M:B*N
+     * reduced by greatest common divisor
+     * so 1:3 with 3:3 is 3:9 or 1:3
+     * 1:3 with 3:1 is 3:3 or 1:1
+     * 1:3 with 1:3 is 1:9
+     * 2:5 with 3:7 is 6:35
+     */
+    int outFromRatio = getFromRatio() * map.getFromRatio();
+    int outToRatio = getToRatio() * map.getToRatio();
+    int gcd = MathUtils.gcd(outFromRatio, outToRatio);
+    outFromRatio /= gcd;
+    outToRatio /= gcd;
+
+    List<int[]> toRanges = new ArrayList<>();
+    List<int[]> ranges = getToRanges();
+    
+    for (int ir = 0, nr = ranges.size(); ir < nr; ir++)
+    {
+      int[] range = ranges.get(ir);
+      int[] transferred = map.locateInTo(range[0], range[1]);
+      if (transferred == null || transferred.length % 2 != 0)
+      {
+        return null;
+      }
+
+      /*
+       *  convert [start1, end1, start2, end2, ...] 
+       *  to [[start1, end1], [start2, end2], ...]
+       */
+      for (int i = 0, n = transferred.length; i < n; i += 2)
+      {
+        toRanges.add(new int[] { transferred[i], transferred[i + 1] });
+      }
+    }
+
+    return new MapList(getFromRanges(), toRanges, outFromRatio, outToRatio);
+  }
+
+}
diff --git a/unused/Mapping.java b/unused/Mapping.java
new file mode 100644 (file)
index 0000000..85f4356
--- /dev/null
@@ -0,0 +1,752 @@
+/*
+ * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
+ * Copyright (C) $$Year-Rel$$ The Jalview Authors
+ * 
+ * This file is part of Jalview.
+ * 
+ * Jalview is free software: you can redistribute it and/or
+ * modify it under the terms of the GNU General Public License 
+ * as published by the Free Software Foundation, either version 3
+ * of the License, or (at your option) any later version.
+ *  
+ * Jalview is distributed in the hope that it will be useful, but 
+ * WITHOUT ANY WARRANTY; without even the implied warranty 
+ * of MERCHANTABILITY or FITNESS FOR A PARTICULAR 
+ * PURPOSE.  See the GNU General Public License for more details.
+ * 
+ * You should have received a copy of the GNU General Public License
+ * along with Jalview.  If not, see <http://www.gnu.org/licenses/>.
+ * The Jalview Authors are detailed in the 'AUTHORS' file.
+ */
+package jalview.datamodel;
+
+import jalview.util.Comparison;
+import jalview.util.MapList;
+
+import java.util.ArrayList;
+import java.util.Iterator;
+import java.util.List;
+import java.util.NoSuchElementException;
+import java.util.Vector;
+
+public class Mapping
+{
+  /**
+   * An iterator that serves the aligned codon positions (with their protein
+   * products).
+   * 
+   * @author gmcarstairs
+   *
+   */
+  public class AlignedCodonIterator implements Iterator<AlignedCodon>
+  {
+    /*
+     * The gap character used in the aligned sequence
+     */
+    private final char gap;
+
+    /*
+     * The characters of the aligned sequence e.g. "-cGT-ACgTG-"
+     */
+    private final SequenceI alignedSeq;
+
+    /*
+     * the sequence start residue
+     */
+    private int start;
+
+    /*
+     * Next position (base 0) in the aligned sequence
+     */
+    private int alignedColumn = 0;
+
+    /*
+     * Count of bases up to and including alignedColumn position
+     */
+    private int alignedBases = 0;
+
+    /*
+     * [start, end] from ranges (base 1)
+     */
+    private Iterator<int[]> fromRanges;
+
+    /*
+     * [start, end] to ranges (base 1)
+     */
+    private Iterator<int[]> toRanges;
+
+    /*
+     * The current [start, end] (base 1) from range
+     */
+    private int[] currentFromRange = null;
+
+    /*
+     * The current [start, end] (base 1) to range
+     */
+    private int[] currentToRange = null;
+
+    /*
+     * The next 'from' position (base 1) to process
+     */
+    private int fromPosition = 0;
+
+    /*
+     * The next 'to' position (base 1) to process
+     */
+    private int toPosition = 0;
+
+    /**
+     * Constructor
+     * 
+     * @param seq
+     *          the aligned sequence
+     * @param gapChar
+     */
+    public AlignedCodonIterator(SequenceI seq, char gapChar)
+    {
+      this.alignedSeq = seq;
+      this.start = seq.getStart();
+      this.gap = gapChar;
+      fromRanges = map.getFromRanges().iterator();
+      toRanges = map.getToRanges().iterator();
+      if (fromRanges.hasNext())
+      {
+        currentFromRange = fromRanges.next();
+        fromPosition = currentFromRange[0];
+      }
+      if (toRanges.hasNext())
+      {
+        currentToRange = toRanges.next();
+        toPosition = currentToRange[0];
+      }
+    }
+
+    /**
+     * Returns true unless we have already traversed the whole mapping.
+     */
+    @Override
+    public boolean hasNext()
+    {
+      if (fromRanges.hasNext())
+      {
+        return true;
+      }
+      if (currentFromRange == null || fromPosition >= currentFromRange[1])
+      {
+        return false;
+      }
+      return true;
+    }
+
+    /**
+     * Returns the next codon's aligned positions, and translated value.
+     * 
+     * @throws NoSuchElementException
+     *           if hasNext() would have returned false
+     * @throws IncompleteCodonException
+     *           if not enough mapped bases are left to make up a codon
+     */
+    @Override
+    public AlignedCodon next() throws IncompleteCodonException
+    {
+      if (!hasNext())
+      {
+        throw new NoSuchElementException();
+      }
+
+      int[] codon = getNextCodon();
+      int[] alignedCodon = getAlignedCodon(codon);
+
+      String peptide = getPeptide();
+      int peptideCol = toPosition - 1 - Mapping.this.to.getStart();
+      return new AlignedCodon(alignedCodon[0], alignedCodon[1],
+              alignedCodon[2], peptide, peptideCol);
+    }
+
+    /**
+     * Retrieve the translation as the 'mapped to' position in the mapped to
+     * sequence.
+     * 
+     * @return
+     * @throws NoSuchElementException
+     *           if the 'toRange' is exhausted (nothing to map to)
+     */
+    private String getPeptide()
+    {
+      // TODO should ideally handle toRatio other than 1 as well...
+      // i.e. code like getNextCodon()
+      if (toPosition <= currentToRange[1])
+      {
+        SequenceI seq = Mapping.this.to;
+        char pep = seq.getCharAt(toPosition - seq.getStart());
+        toPosition++;
+        return String.valueOf(pep);
+      }
+      if (!toRanges.hasNext())
+      {
+        throw new NoSuchElementException(
+                "Ran out of peptide at position " + toPosition);
+      }
+      currentToRange = toRanges.next();
+      toPosition = currentToRange[0];
+      return getPeptide();
+    }
+
+    /**
+     * Get the (base 1) dataset positions for the next codon in the mapping.
+     * 
+     * @throws IncompleteCodonException
+     *           if less than 3 remaining bases are mapped
+     */
+    private int[] getNextCodon()
+    {
+      int[] codon = new int[3];
+      int codonbase = 0;
+
+      while (codonbase < 3)
+      {
+        if (fromPosition <= currentFromRange[1])
+        {
+          /*
+           * Add next position from the current start-end range
+           */
+          codon[codonbase++] = fromPosition++;
+        }
+        else
+        {
+          /*
+           * Move to the next range - if there is one
+           */
+          if (!fromRanges.hasNext())
+          {
+            throw new IncompleteCodonException();
+          }
+          currentFromRange = fromRanges.next();
+          fromPosition = currentFromRange[0];
+        }
+      }
+      return codon;
+    }
+
+    /**
+     * Get the aligned column positions (base 0) for the given sequence
+     * positions (base 1), by counting ungapped characters in the aligned
+     * sequence.
+     * 
+     * @param codon
+     * @return
+     */
+    private int[] getAlignedCodon(int[] codon)
+    {
+      int[] aligned = new int[codon.length];
+      for (int i = 0; i < codon.length; i++)
+      {
+        aligned[i] = getAlignedColumn(codon[i]);
+      }
+      return aligned;
+    }
+
+    /**
+     * Get the aligned column position (base 0) for the given sequence position
+     * (base 1).
+     * 
+     * @param sequencePos
+     * @return
+     */
+    private int getAlignedColumn(int sequencePos)
+    {
+      /*
+       * allow for offset e.g. treat pos 8 as 2 if sequence starts at 7
+       */
+      int truePos = sequencePos - (start - 1);
+      int length = alignedSeq.getLength();
+      while (alignedBases < truePos && alignedColumn < length)
+      {
+        char c = alignedSeq.getCharAt(alignedColumn++);
+        if (c != gap && !Comparison.isGap(c))
+        {
+          alignedBases++;
+        }
+      }
+      return alignedColumn - 1;
+    }
+
+    @Override
+    public void remove()
+    {
+      // ignore
+    }
+
+  }
+
+  /*
+   * Contains the start-end pairs mapping from the associated sequence to the
+   * sequence in the database coordinate system. It also takes care of step
+   * difference between coordinate systems.
+   */
+  MapList map = null;
+
+  /*
+   * The sequence that map maps the associated sequence to (if any).
+   */
+  SequenceI to = null;
+
+  /*
+   * optional sequence id for the 'from' ranges
+   */
+  private String mappedFromId;
+
+  public Mapping(MapList map)
+  {
+    super();
+    this.map = map;
+  }
+
+  public Mapping(SequenceI to, MapList map)
+  {
+    this(map);
+    this.to = to;
+  }
+
+  /**
+   * create a new mapping from
+   * 
+   * @param to
+   *          the sequence being mapped
+   * @param exon
+   *          int[] {start,end,start,end} series on associated sequence
+   * @param is
+   *          int[] {start,end,...} ranges on the reference frame being mapped
+   *          to
+   * @param i
+   *          step size on associated sequence
+   * @param j
+   *          step size on mapped frame
+   */
+  public Mapping(SequenceI to, int[] exon, int[] is, int i, int j)
+  {
+    this(to, new MapList(exon, is, i, j));
+  }
+
+  /**
+   * create a duplicate (and independent) mapping object with the same reference
+   * to any SequenceI being mapped to.
+   * 
+   * @param map2
+   */
+  public Mapping(Mapping map2)
+  {
+    if (map2 != this && map2 != null)
+    {
+      if (map2.map != null)
+      {
+        map = new MapList(map2.map);
+      }
+      to = map2.to;
+      mappedFromId = map2.mappedFromId;
+    }
+  }
+
+  /**
+   * @return the map
+   */
+  public MapList getMap()
+  {
+    return map;
+  }
+
+  /**
+   * @param map
+   *          the map to set
+   */
+  public void setMap(MapList map)
+  {
+    this.map = map;
+  }
+
+  /**
+   * Equals that compares both the to references and MapList mappings.
+   * 
+   * @param o
+   * @return
+   * @see MapList#equals
+   */
+  @Override
+  public boolean equals(Object o)
+  {
+    if (o == null || !(o instanceof Mapping))
+    {
+      return false;
+    }
+    Mapping other = (Mapping) o;
+    if (other == this)
+    {
+      return true;
+    }
+    if (other.to != to)
+    {
+      return false;
+    }
+    if ((map != null && other.map == null)
+            || (map == null && other.map != null))
+    {
+      return false;
+    }
+    if ((map == null && other.map == null) || map.equals(other.map))
+    {
+      return true;
+    }
+    return false;
+  }
+
+  /**
+   * Returns a hashCode made from the sequence and maplist
+   */
+  @Override
+  public int hashCode()
+  {
+    int hashCode = (this.to == null ? 1 : this.to.hashCode());
+    if (this.map != null)
+    {
+      hashCode = hashCode * 31 + this.map.hashCode();
+    }
+
+    return hashCode;
+  }
+
+//  /**
+//   * gets boundary in direction of mapping
+//   * 
+//   * @param position
+//   *          in mapped reference frame
+//   * @return int{start, end} positions in associated sequence (in direction of
+//   *         mapped word)
+//   */
+//  public int[] getWord(int mpos)
+//  {
+//       // BH never called
+//    if (map != null)
+//    {
+//      return map.getToWord(mpos);
+//    }
+//    return null;
+//  }
+
+  /**
+   * width of mapped unit in associated sequence
+   * 
+   */
+  public int getWidth()
+  {
+    if (map != null)
+    {
+      return map.getFromRatio();
+    }
+    return 1;
+  }
+
+  /**
+   * width of unit in mapped reference frame
+   * 
+   * @return
+   */
+  public int getMappedWidth()
+  {
+    if (map != null)
+    {
+      return map.getToRatio();
+    }
+    return 1;
+  }
+
+       /**
+        * get the 'initial' position in the associated sequence for a position in the
+        * mapped reference frame
+        * 
+        * or the mapped position in the associated reference frame for position pos in
+        * the associated sequence.
+        * 
+        * 
+        * @param reg      reg[POS]
+        * @param isMapped
+        * 
+        * @return position or mapped position
+        */
+  public int getPosition(int[] reg, boolean isMapped)
+  {
+       int pos = reg[MapList.POS];
+    if (map != null)
+    {
+      reg = (isMapped ? map.shiftFrom(reg) : map.shiftTo(reg));
+      if (reg != null)
+      {
+          return reg[MapList.POS_TO]; // was newArray[0], but shift puts the result in COUNT_TO
+      }
+    }
+    return pos;
+  }
+
+//  /**
+//* get mapped position in the associated reference frame for position pos in
+//* the associated sequence.
+//   * 
+//   * @param pos
+//   * @return
+//   */
+//  public int getMappedPosition(int[] reg)
+//  {
+//     int mpos = reg[MapList.POS]; 
+//    if (map != null)
+//    {
+//      reg = map.shiftFrom(reg);
+//      if (reg != null)
+//      {
+//        return reg[MapList.POS_TO]; // was newArray[0], but shift puts the result in COUNT_TO
+//      }
+//    }
+//    return mpos;
+//  }
+
+//  public int[] getMappedWord(int pos)
+//  {
+//       // BH Not used? 
+//    if (map != null)
+//    {
+//      reg = map.shiftFrom(reg);
+//      if (reg != null)
+//      {
+//     reg[MP_0] = 
+//        return new int[] { mp[0], mp[0] + mp[2] * (map.getToRatio() - 1) };
+//      }
+//    }
+//    return null;
+//  }
+
+  /**
+   * locates the region of feature f in the associated sequence's reference
+   * frame
+   * 
+   * @param f
+   * @return one or more features corresponding to f
+   */
+  public SequenceFeature[] locateFeature(SequenceFeature f)
+  {
+    if (true)
+    { // f.getBegin()!=f.getEnd()) {
+      if (map != null)
+      {
+        int[] frange = map.locateInFrom(f.getBegin(), f.getEnd());
+        if (frange == null)
+        {
+          // JBPNote - this isprobably not the right thing to doJBPHack
+          return null;
+        }
+        SequenceFeature[] vf = new SequenceFeature[frange.length / 2];
+        for (int i = 0, v = 0; i < frange.length; i += 2, v++)
+        {
+          vf[v] = new SequenceFeature(f, frange[i], frange[i + 1],
+                  f.getFeatureGroup(), f.getScore());
+          if (frange.length > 2)
+          {
+            vf[v].setDescription(f.getDescription() + "\nPart " + (v + 1));
+          }
+        }
+        return vf;
+      }
+    }
+
+    // give up and just return the feature.
+    return new SequenceFeature[] { f };
+  }
+
+  /**
+   * return a series of contigs on the associated sequence corresponding to the
+   * from,to interval on the mapped reference frame
+   * 
+   * @param from
+   * @param to
+   * @return int[] { from_i, to_i for i=1 to n contiguous regions in the
+   *         associated sequence}
+   */
+  public int[] locateRange(int from, int to)
+  {
+    if (map != null)
+    {
+      if (from <= to)
+      {
+        from = (map.getToLowest() < from) ? from : map.getToLowest();
+        to = (map.getToHighest() > to) ? to : map.getToHighest();
+        if (from > to)
+        {
+          return null;
+        }
+      }
+      else
+      {
+        from = (map.getToHighest() > from) ? from : map.getToHighest();
+        to = (map.getToLowest() < to) ? to : map.getToLowest();
+        if (from < to)
+        {
+          return null;
+        }
+      }
+      return map.locateInFrom(from, to);
+    }
+    return new int[] { from, to };
+  }
+
+  /**
+   * return a series of mapped contigs mapped from a range on the associated
+   * sequence
+   * 
+   * @param from
+   * @param to
+   * @return
+   */
+  public int[] locateMappedRange(int from, int to)
+  {
+    if (map != null)
+    {
+
+      if (from <= to)
+      {
+        from = (map.getFromLowest() < from) ? from : map.getFromLowest();
+        to = (map.getFromHighest() > to) ? to : map.getFromHighest();
+        if (from > to)
+        {
+          return null;
+        }
+      }
+      else
+      {
+        from = (map.getFromHighest() > from) ? from : map.getFromHighest();
+        to = (map.getFromLowest() < to) ? to : map.getFromLowest();
+        if (from < to)
+        {
+          return null;
+        }
+      }
+      return map.locateInTo(from, to);
+    }
+    return new int[] { from, to };
+  }
+
+  /**
+   * return a new mapping object with a maplist modifed to only map the visible
+   * regions defined by viscontigs.
+   * 
+   * @param viscontigs
+   * @return
+   */
+  public Mapping intersectVisContigs(int[] viscontigs)
+  {
+    Mapping copy = new Mapping(this);
+    if (map != null)
+    {
+//      int vpos = 0;
+//      int apos = 0;
+      List<int[]> toRange = new ArrayList<int[]>();
+      List<int[]> fromRange = new ArrayList<int[]>();
+      for (int vc = 0; vc < viscontigs.length; vc += 2)
+      {
+        // find a mapped range in this visible region
+        int[] mpr = locateMappedRange(1 + viscontigs[vc],
+                viscontigs[vc + 1] - 1);
+        if (mpr != null)
+        {
+          for (int m = 0; m < mpr.length; m += 2)
+          {
+            toRange.add(new int[] { mpr[m], mpr[m + 1] });
+            int[] xpos = locateRange(mpr[m], mpr[m + 1]);
+            for (int x = 0; x < xpos.length; x += 2)
+            {
+              fromRange.add(new int[] { xpos[x], xpos[x + 1] });
+            }
+          }
+        }
+      }
+      int[] from = new int[fromRange.size() * 2];
+      int[] to = new int[toRange.size() * 2];
+      int[] r;
+      for (int f = 0, fSize = fromRange.size(); f < fSize; f++)
+      {
+        r = fromRange.get(f);
+        from[f * 2] = r[0];
+        from[f * 2 + 1] = r[1];
+      }
+      for (int f = 0, fSize = toRange.size(); f < fSize; f++)
+      {
+        r = toRange.get(f);
+        to[f * 2] = r[0];
+        to[f * 2 + 1] = r[1];
+      }
+      copy.setMap(
+              new MapList(from, to, map.getFromRatio(), map.getToRatio()));
+    }
+    return copy;
+  }
+
+  /**
+   * get the sequence being mapped to - if any
+   * 
+   * @return null or a dataset sequence
+   */
+  public SequenceI getTo()
+  {
+    return to;
+  }
+
+  /**
+   * set the dataset sequence being mapped to if any
+   * 
+   * @param tto
+   */
+  public void setTo(SequenceI tto)
+  {
+    to = tto;
+  }
+
+  /**
+   * Returns an iterator which can serve up the aligned codon column positions
+   * and their corresponding peptide products
+   * 
+   * @param seq
+   *          an aligned (i.e. possibly gapped) sequence
+   * @param gapChar
+   * @return
+   */
+  public Iterator<AlignedCodon> getCodonIterator(SequenceI seq,
+          char gapChar)
+  {
+    return new AlignedCodonIterator(seq, gapChar);
+  }
+
+  /**
+   * Readable representation for debugging only, not guaranteed not to change
+   */
+  @Override
+  public String toString()
+  {
+    return String.format("%s %s", this.map.toString(),
+            this.to == null ? "" : this.to.getName());
+  }
+
+  /**
+   * Returns the identifier for the 'from' range sequence, or null if not set
+   * 
+   * @return
+   */
+  public String getMappedFromId()
+  {
+    return mappedFromId;
+  }
+
+  /**
+   * Sets the identifier for the 'from' range sequence
+   */
+  public void setMappedFromId(String mappedFromId)
+  {
+    this.mappedFromId = mappedFromId;
+  }
+
+}