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{
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{
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{
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{
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+ "experimental_method":["Solution NMR"],
+ "pdb_id":"6x4x",
+ "title":"B24Y DKP insulin"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"6jr3",
+ "resolution":14.5,
+ "title":"Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"6jr3",
+ "resolution":14.5,
+ "title":"Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"1os4",
"resolution":2.25,
- "title":"Crystal structure of MN human arg-insulin"},
+ "title":"Dehydrated T6 human insulin at 295 K"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1kmf",
- "title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
+ "pdb_id":"2kju",
+ "title":"NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2ws4",
+ "resolution":1.9,
+ "title":"Semi-synthetic analogue of human insulin ProB26-DTI in monomer form"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2qiu",
+ "resolution":2.0,
+ "title":"Structure of Human Arg-Insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1kmf",
- "title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
+ "pdb_id":"2kjj",
+ "title":"Dynamics of insulin probed by 1H-NMR amide proton exchange anomalous flexibility of the receptor-binding surface"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2kjj",
+ "title":"Dynamics of insulin probed by 1H-NMR amide proton exchange anomalous flexibility of the receptor-binding surface"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3zi3",
+ "resolution":1.7,
+ "title":"Crystal structure of the B24His-insulin - human analogue"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3zi3",
+ "resolution":1.7,
+ "title":"Crystal structure of the B24His-insulin - human analogue"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2jv1",
+ "title":"NMR structure of human insulin monomer in 35% CD3CN zinc free, 50 structures"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1jco",
+ "title":"Solution structure of the monomeric [Thr(B27)->Pro,Pro(B28)->Thr] insulin mutant (PT insulin)"},
{
"experimental_method":["Solution NMR"],
"pdb_id":"1ioh",
"title":"INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
+ "pdb_id":"1iog",
+ "title":"INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES"},
+ {
+ "experimental_method":["Solution NMR"],
"pdb_id":"1hui",
"title":"INSULIN MUTANT (B1, B10, B16, B27)GLU, DES-B30, NMR, 25 STRUCTURES"},
{
"pdb_id":"1hui",
"title":"INSULIN MUTANT (B1, B10, B16, B27)GLU, DES-B30, NMR, 25 STRUCTURES"},
{
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1a7f",
+ "title":"INSULIN MUTANT B16 GLU, B24 GLY, DES-B30, NMR, 20 STRUCTURES"},
+ {
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1os4",
+ "pdb_id":"3i40",
+ "resolution":1.85,
+ "title":"Human insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2r35",
+ "resolution":2.08,
+ "title":"Crystal structure of RB human arg-insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2r34",
"resolution":2.25,
- "title":"Dehydrated T6 human insulin at 295 K"},
+ "title":"Crystal structure of MN human arg-insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1a7f",
- "title":"INSULIN MUTANT B16 GLU, B24 GLY, DES-B30, NMR, 20 STRUCTURES"},
+ "pdb_id":"2juu",
+ "title":"allo-ThrA3 DKP-insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2kju",
- "title":"NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures"},
+ "pdb_id":"2jum",
+ "title":"ThrA3-DKP-insulin"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3ilg",
- "resolution":1.9,
- "title":"Crystal structure of humnan insulin Sr+2 complex"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2jum",
+ "title":"ThrA3-DKP-insulin"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1xgl",
+ "title":"HUMAN INSULIN DISULFIDE ISOMER, NMR, 10 STRUCTURES"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1xgl",
+ "title":"HUMAN INSULIN DISULFIDE ISOMER, NMR, 10 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
"pdb_id":"1t1k",
"pdb_id":"1t1k",
"title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-ALA, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
{
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1kmf",
+ "title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1kmf",
+ "title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3ilg",
+ "resolution":1.9,
+ "title":"Crystal structure of humnan insulin Sr+2 complex"},
+ {
"experimental_method":["X-ray diffraction"],
"pdb_id":"5t7r",
"resolution":1.55,
"resolution":1.55,
"title":"A6-A11 trans-dicarba human insulin"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"5mwq",
- "title":"Biosynthetic engineered A21K-B31K-B32R human insulin monomer structure in water/acetonitrile solution"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"7jp3",
+ "resolution":1.95,
+ "title":"Des-B29,B30-insulin"},
{
- "experimental_method":["Electron Microscopy"],
- "pdb_id":"6jr3",
- "resolution":14.5,
- "title":"Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4ak0",
+ "resolution":2.28,
+ "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
{
- "experimental_method":["Electron Microscopy"],
- "pdb_id":"6jr3",
- "resolution":14.5,
- "title":"Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4ak0",
+ "resolution":2.28,
+ "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"6x4x",
- "title":"B24Y DKP insulin"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4unh",
+ "resolution":2.75,
+ "title":"Human insulin B26Gly mutant crystal structure"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"6x4x",
- "title":"B24Y DKP insulin"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4unh",
+ "resolution":2.75,
+ "title":"Human insulin B26Gly mutant crystal structure"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5ena",
- "resolution":1.35,
- "title":"Xray crystal structure of isotope-labeled human insulin"},
+ "pdb_id":"5uoz",
+ "resolution":1.1746387,
+ "title":"Insulin with proline analog FyP at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3u4n",
- "resolution":1.98,
- "title":"A novel covalently linked insulin dimer"},
+ "pdb_id":"5uoz",
+ "resolution":1.1746387,
+ "title":"Insulin with proline analog FyP at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3u4n",
- "resolution":1.98,
- "title":"A novel covalently linked insulin dimer"},
+ "pdb_id":"4ung",
+ "resolution":1.81,
+ "title":"Human insulin B26Asn mutant crystal structure"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3zi3",
- "resolution":1.7,
- "title":"Crystal structure of the B24His-insulin - human analogue"},
+ "pdb_id":"4iyd",
+ "resolution":1.66,
+ "title":"Insulin glargine crystal structure 1"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3zi3",
- "resolution":1.7,
- "title":"Crystal structure of the B24His-insulin - human analogue"},
+ "pdb_id":"4iyd",
+ "resolution":1.66,
+ "title":"Insulin glargine crystal structure 1"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2h67",
+ "title":"NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2h67",
+ "title":"NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5en9",
- "resolution":1.5,
- "title":"High resolution x-ray crystal structure of isotope-labeled ester-insulin"},
+ "pdb_id":"6s34",
+ "resolution":1.35,
+ "title":"Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"7jp3",
- "resolution":1.95,
- "title":"Des-B29,B30-insulin"},
+ "pdb_id":"6s34",
+ "resolution":1.35,
+ "title":"Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3i40",
+ "pdb_id":"6ves",
"resolution":1.85,
- "title":"Human insulin"},
+ "title":"Human insulin analog: [GluB10,HisA8,ArgA9]-DOI"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"2hho",
- "title":"NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"6ves",
+ "resolution":1.85,
+ "title":"Human insulin analog: [GluB10,HisA8,ArgA9]-DOI"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2juu",
- "title":"allo-ThrA3 DKP-insulin"},
+ "pdb_id":"2mpg",
+ "title":"Solution structure of the [AibB8,LysB28,ProB29]-insulin analogue"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"2h67",
- "title":"NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"1os4",
+ "resolution":2.25,
+ "title":"Dehydrated T6 human insulin at 295 K"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2h67",
- "title":"NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
+ "pdb_id":"2kju",
+ "title":"NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2qiu",
+ "resolution":2.0,
+ "title":"Structure of Human Arg-Insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2jv1",
- "title":"NMR structure of human insulin monomer in 35% CD3CN zinc free, 50 structures"},
+ "pdb_id":"2aiy",
+ "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 20 STRUCTURES"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2ws0",
+ "resolution":2.1,
+ "title":"Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5"},
{
"experimental_method":["Solution NMR"],
"pdb_id":"2juv",
"pdb_id":"2juv",
"title":"AbaA3-DKP-insulin"},
{
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2hho",
+ "title":"NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
+ {
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2ws0",
- "resolution":2.1,
- "title":"Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5"},
+ "pdb_id":"3w7y",
+ "resolution":0.92,
+ "title":"0.92A structure of 2Zn human insulin at 100K"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3w7y",
+ "resolution":0.92,
+ "title":"0.92A structure of 2Zn human insulin at 100K"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1iog",
- "title":"INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES"},
+ "pdb_id":"2jv1",
+ "title":"NMR structure of human insulin monomer in 35% CD3CN zinc free, 50 structures"},
{
"experimental_method":["Solution NMR"],
"pdb_id":"1jco",
"title":"Solution structure of the monomeric [Thr(B27)->Pro,Pro(B28)->Thr] insulin mutant (PT insulin)"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1t1p",
- "title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-THR, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
+ "pdb_id":"1ioh",
+ "title":"INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1t1p",
- "title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-THR, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
+ "pdb_id":"1hls",
+ "title":"NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16)"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1hls",
+ "title":"NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16)"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1iog",
+ "title":"INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"1a7f",
+ "title":"INSULIN MUTANT B16 GLU, B24 GLY, DES-B30, NMR, 20 STRUCTURES"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"1mso",
+ "resolution":1.0,
+ "title":"T6 Human Insulin at 1.0 A Resolution"},
{
"experimental_method":["Solution NMR"],
"pdb_id":"1t1q",
"title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-ABA, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1sf1",
- "title":"NMR STRUCTURE OF HUMAN INSULIN under Amyloidogenic Condition, 15 STRUCTURES"},
+ "pdb_id":"1t1p",
+ "title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-THR, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1sf1",
- "title":"NMR STRUCTURE OF HUMAN INSULIN under Amyloidogenic Condition, 15 STRUCTURES"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"2r35",
- "resolution":2.08,
- "title":"Crystal structure of RB human arg-insulin"},
+ "pdb_id":"1t1p",
+ "title":"NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-THR, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2qiu",
- "resolution":2.0,
- "title":"Structure of Human Arg-Insulin"},
+ "pdb_id":"3i40",
+ "resolution":1.85,
+ "title":"Human insulin"},
{
"experimental_method":["Solution NMR"],
"pdb_id":"2rn5",
"pdb_id":"2rn5",
"title":"Humal Insulin Mutant B31Lys-B32Arg"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"2lgb",
- "title":"Modified A22Gly-B31Arg Human Insulin"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3i3z",
+ "resolution":1.6,
+ "title":"Human insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3i3z",
+ "resolution":1.6,
+ "title":"Human insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2r35",
+ "resolution":2.08,
+ "title":"Crystal structure of RB human arg-insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2lgb",
- "title":"Modified A22Gly-B31Arg Human Insulin"},
+ "pdb_id":"2juu",
+ "title":"allo-ThrA3 DKP-insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1ioh",
- "title":"INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES"},
+ "pdb_id":"1sf1",
+ "title":"NMR STRUCTURE OF HUMAN INSULIN under Amyloidogenic Condition, 15 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1a7f",
- "title":"INSULIN MUTANT B16 GLU, B24 GLY, DES-B30, NMR, 20 STRUCTURES"},
+ "pdb_id":"1sf1",
+ "title":"NMR STRUCTURE OF HUMAN INSULIN under Amyloidogenic Condition, 15 STRUCTURES"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1mso",
- "resolution":1.0,
- "title":"T6 Human Insulin at 1.0 A Resolution"},
+ "pdb_id":"3w7z",
+ "resolution":1.15,
+ "title":"1.15A structure of human 2Zn insulin at 293K"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1os4",
- "resolution":2.25,
- "title":"Dehydrated T6 human insulin at 295 K"},
+ "pdb_id":"3w7z",
+ "resolution":1.15,
+ "title":"1.15A structure of human 2Zn insulin at 293K"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1hls",
- "title":"NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16)"},
+ "pdb_id":"2lgb",
+ "title":"Modified A22Gly-B31Arg Human Insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1hls",
- "title":"NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16)"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3i3z",
- "resolution":1.6,
- "title":"Human insulin"},
+ "pdb_id":"2lgb",
+ "title":"Modified A22Gly-B31Arg Human Insulin"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3i3z",
- "resolution":1.6,
- "title":"Human insulin"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2hiu",
+ "title":"NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2kju",
- "title":"NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures"},
+ "pdb_id":"2hiu",
+ "title":"NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2aiy",
- "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 20 STRUCTURES"},
+ "pdb_id":"2m2m",
+ "title":"Structure of [L-HisB24] insulin analogue at pH 1.9"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6ves",
- "resolution":1.85,
- "title":"Human insulin analog: [GluB10,HisA8,ArgA9]-DOI"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2m2m",
+ "title":"Structure of [L-HisB24] insulin analogue at pH 1.9"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6ves",
- "resolution":1.85,
- "title":"Human insulin analog: [GluB10,HisA8,ArgA9]-DOI"},
+ "pdb_id":"3tt8",
+ "resolution":1.12,
+ "title":"Crystal Structure Analysis of Cu Human Insulin Derivative"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6s34",
- "resolution":1.35,
- "title":"Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution"},
+ "pdb_id":"3tt8",
+ "resolution":1.12,
+ "title":"Crystal Structure Analysis of Cu Human Insulin Derivative"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6s34",
- "resolution":1.35,
- "title":"Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution"},
+ "pdb_id":"4iyf",
+ "resolution":1.8,
+ "title":"Insulin glargine crystal structure 2"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ung",
- "resolution":1.81,
- "title":"Human insulin B26Asn mutant crystal structure"},
+ "pdb_id":"4iyf",
+ "resolution":1.8,
+ "title":"Insulin glargine crystal structure 2"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4unh",
- "resolution":2.75,
- "title":"Human insulin B26Gly mutant crystal structure"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2kqq",
+ "title":"NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4unh",
- "resolution":2.75,
- "title":"Human insulin B26Gly mutant crystal structure"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2kxk",
+ "title":"Human Insulin Mutant A22Gly-B31Lys-B32Arg"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2mpg",
- "title":"Solution structure of the [AibB8,LysB28,ProB29]-insulin analogue"},
+ "pdb_id":"2kxk",
+ "title":"Human Insulin Mutant A22Gly-B31Lys-B32Arg"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4iyd",
- "resolution":1.66,
- "title":"Insulin glargine crystal structure 1"},
+ "pdb_id":"4cxn",
+ "resolution":1.7,
+ "title":"Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4iyd",
- "resolution":1.66,
- "title":"Insulin glargine crystal structure 1"},
+ "pdb_id":"4cxn",
+ "resolution":1.7,
+ "title":"Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3w7z",
- "resolution":1.15,
- "title":"1.15A structure of human 2Zn insulin at 293K"},
+ "pdb_id":"5hqi",
+ "resolution":0.97,
+ "title":"Insulin with proline analog HzP at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3w7z",
- "resolution":1.15,
- "title":"1.15A structure of human 2Zn insulin at 293K"},
+ "pdb_id":"5hqi",
+ "resolution":0.97,
+ "title":"Insulin with proline analog HzP at position B28 in the T2 state"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3w7y",
- "resolution":0.92,
- "title":"0.92A structure of 2Zn human insulin at 100K"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"5mhd",
+ "title":"Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions."},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3w7y",
- "resolution":0.92,
- "title":"0.92A structure of 2Zn human insulin at 100K"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"5mhd",
+ "title":"Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions."},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4ak0",
- "resolution":2.28,
- "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"4aiy",
+ "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'GREEN' SUBSTATE, AVERAGE STRUCTURE"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4ak0",
- "resolution":2.28,
- "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"4aiy",
+ "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'GREEN' SUBSTATE, AVERAGE STRUCTURE"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5uoz",
- "resolution":1.1746387,
- "title":"Insulin with proline analog FyP at position B28 in the T2 state"},
+ "pdb_id":"4une",
+ "resolution":1.59,
+ "title":"Human insulin B26Phe mutant crystal structure"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5uoz",
- "resolution":1.1746387,
- "title":"Insulin with proline analog FyP at position B28 in the T2 state"},
+ "pdb_id":"4une",
+ "resolution":1.59,
+ "title":"Human insulin B26Phe mutant crystal structure"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"2hiu",
- "title":"NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4ung",
+ "resolution":1.81,
+ "title":"Human insulin B26Asn mutant crystal structure"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2hiu",
- "title":"NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES"},
+ "pdb_id":"2n2w",
+ "title":"Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2m2m",
- "title":"Structure of [L-HisB24] insulin analogue at pH 1.9"},
+ "pdb_id":"2mpi",
+ "title":"Solution structure of B24G insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2m2m",
- "title":"Structure of [L-HisB24] insulin analogue at pH 1.9"},
+ "pdb_id":"2mpi",
+ "title":"Solution structure of B24G insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2hho",
- "title":"NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
+ "pdb_id":"2n2v",
+ "title":"Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 1.9"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2k91",
- "title":"Enhancing the activity of insulin by stereospecific unfolding"},
+ "pdb_id":"2mpg",
+ "title":"Solution structure of the [AibB8,LysB28,ProB29]-insulin analogue"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2k91",
- "title":"Enhancing the activity of insulin by stereospecific unfolding"},
+ "pdb_id":"2l1y",
+ "title":"NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2hh4",
- "title":"NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
+ "pdb_id":"5aiy",
+ "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2hh4",
- "title":"NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"2ws0",
- "resolution":2.1,
- "title":"Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5"},
+ "pdb_id":"5aiy",
+ "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"1os3",
- "resolution":1.95,
- "title":"Dehydrated T6 human insulin at 100 K"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2mli",
+ "title":"NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"1os3",
- "resolution":1.95,
- "title":"Dehydrated T6 human insulin at 100 K"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2n2x",
+ "title":"Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9"},
{
"experimental_method":["Solution NMR"],
"pdb_id":"3aiy",
"pdb_id":"3aiy",
"title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, REFINED AVERAGE STRUCTURE"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3inc",
- "resolution":1.85,
- "title":"Crystal structure of human insulin with Ni+2 complex"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2aiy",
+ "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 20 STRUCTURES"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3inc",
- "resolution":1.85,
- "title":"Crystal structure of human insulin with Ni+2 complex"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2kxk",
- "title":"Human Insulin Mutant A22Gly-B31Lys-B32Arg"},
+ "pdb_id":"2wrx",
+ "resolution":1.5,
+ "title":"Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4cxn",
- "resolution":1.7,
- "title":"Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I"},
+ "pdb_id":"2wrx",
+ "resolution":1.5,
+ "title":"Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4cxn",
- "resolution":1.7,
- "title":"Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I"},
+ "pdb_id":"2ws0",
+ "resolution":2.1,
+ "title":"Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2r34",
- "resolution":2.25,
- "title":"Crystal structure of MN human arg-insulin"},
+ "pdb_id":"2g56",
+ "resolution":2.2,
+ "title":"crystal structure of human insulin-degrading enzyme in complex with insulin B chain"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"2kxk",
- "title":"Human Insulin Mutant A22Gly-B31Lys-B32Arg"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4eww",
+ "resolution":2.3,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2wrx",
- "resolution":1.5,
- "title":"Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0"},
+ "pdb_id":"3w80",
+ "resolution":1.4,
+ "title":"Crystal structure of dodecamer human insulin with double C-axis length of the hexamer 2 Zn insulin cell"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2wrx",
- "resolution":1.5,
- "title":"Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0"},
+ "pdb_id":"3w80",
+ "resolution":1.4,
+ "title":"Crystal structure of dodecamer human insulin with double C-axis length of the hexamer 2 Zn insulin cell"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1mhi",
- "title":"THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN INSULIN DIMER. A STUDY OF THE B9(ASP) MUTANT OF HUMAN INSULIN USING NUCLEAR MAGNETIC RESONANCE DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS"},
+ "pdb_id":"2hh4",
+ "title":"NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1mhi",
- "title":"THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN INSULIN DIMER. A STUDY OF THE B9(ASP) MUTANT OF HUMAN INSULIN USING NUCLEAR MAGNETIC RESONANCE DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS"},
+ "pdb_id":"2hh4",
+ "title":"NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1mhj",
- "title":"SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN"},
+ "pdb_id":"2hho",
+ "title":"NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4ewx",
+ "resolution":2.201,
+ "title":"Human Insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1mhj",
- "title":"SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN"},
+ "pdb_id":"2k91",
+ "title":"Enhancing the activity of insulin by stereospecific unfolding"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1aiy",
- "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES"},
+ "pdb_id":"2k91",
+ "title":"Enhancing the activity of insulin by stereospecific unfolding"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"1mso",
"title":"T6 Human Insulin at 1.0 A Resolution"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2g56",
- "resolution":2.2,
- "title":"crystal structure of human insulin-degrading enzyme in complex with insulin B chain"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2aiy",
- "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 20 STRUCTURES"},
+ "pdb_id":"1os3",
+ "resolution":1.95,
+ "title":"Dehydrated T6 human insulin at 100 K"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2kqq",
- "title":"NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures"},
+ "pdb_id":"1mhj",
+ "title":"SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2l1y",
- "title":"NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures"},
+ "pdb_id":"1mhj",
+ "title":"SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2n2v",
- "title":"Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 1.9"},
+ "pdb_id":"1mhi",
+ "title":"THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN INSULIN DIMER. A STUDY OF THE B9(ASP) MUTANT OF HUMAN INSULIN USING NUCLEAR MAGNETIC RESONANCE DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2n2w",
- "title":"Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0"},
+ "pdb_id":"1mhi",
+ "title":"THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN INSULIN DIMER. A STUDY OF THE B9(ASP) MUTANT OF HUMAN INSULIN USING NUCLEAR MAGNETIC RESONANCE DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4une",
- "resolution":1.59,
- "title":"Human insulin B26Phe mutant crystal structure"},
+ "pdb_id":"1os3",
+ "resolution":1.95,
+ "title":"Dehydrated T6 human insulin at 100 K"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4une",
- "resolution":1.59,
- "title":"Human insulin B26Phe mutant crystal structure"},
+ "pdb_id":"2r34",
+ "resolution":2.25,
+ "title":"Crystal structure of MN human arg-insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ung",
- "resolution":1.81,
- "title":"Human insulin B26Asn mutant crystal structure"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2mpi",
- "title":"Solution structure of B24G insulin"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2mpi",
- "title":"Solution structure of B24G insulin"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2mpg",
- "title":"Solution structure of the [AibB8,LysB28,ProB29]-insulin analogue"},
+ "pdb_id":"3inc",
+ "resolution":1.85,
+ "title":"Crystal structure of human insulin with Ni+2 complex"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"2mli",
- "title":"NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3inc",
+ "resolution":1.85,
+ "title":"Crystal structure of human insulin with Ni+2 complex"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3w80",
- "resolution":1.4,
- "title":"Crystal structure of dodecamer human insulin with double C-axis length of the hexamer 2 Zn insulin cell"},
+ "pdb_id":"3q6e",
+ "resolution":2.05,
+ "title":"Human insulin in complex with cucurbit[7]uril"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3w80",
- "resolution":1.4,
- "title":"Crystal structure of dodecamer human insulin with double C-axis length of the hexamer 2 Zn insulin cell"},
+ "pdb_id":"3q6e",
+ "resolution":2.05,
+ "title":"Human insulin in complex with cucurbit[7]uril"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"4aiy",
- "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'GREEN' SUBSTATE, AVERAGE STRUCTURE"},
+ "pdb_id":"2kqq",
+ "title":"NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"4aiy",
- "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'GREEN' SUBSTATE, AVERAGE STRUCTURE"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"5urt",
+ "resolution":1.18,
+ "title":"Insulin with proline analog DhP at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ewx",
- "resolution":2.201,
- "title":"Human Insulin"},
+ "pdb_id":"5usv",
+ "resolution":1.3,
+ "title":"Insulin with proline analog AzeP at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3tt8",
- "resolution":1.12,
- "title":"Crystal Structure Analysis of Cu Human Insulin Derivative"},
+ "pdb_id":"5usv",
+ "resolution":1.3,
+ "title":"Insulin with proline analog AzeP at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3tt8",
- "resolution":1.12,
- "title":"Crystal Structure Analysis of Cu Human Insulin Derivative"},
+ "pdb_id":"5uu2",
+ "resolution":1.223,
+ "title":"Insulin with proline analog ThioP at position B28 in the T2 state"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2n2w",
+ "title":"Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0"},
+ {
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2n2v",
+ "title":"Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 1.9"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4iyf",
- "resolution":1.8,
- "title":"Insulin glargine crystal structure 2"},
+ "pdb_id":"5usp",
+ "resolution":1.174,
+ "title":"Insulin with proline analog Pip at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4iyf",
- "resolution":1.8,
- "title":"Insulin glargine crystal structure 2"},
+ "pdb_id":"5usp",
+ "resolution":1.174,
+ "title":"Insulin with proline analog Pip at position B28 in the T2 state"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"5aiy",
- "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE"},
+ "pdb_id":"2l1y",
+ "title":"NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"5aiy",
- "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"5bpo",
+ "resolution":1.9,
+ "title":"Human insulin with intra-chain chemical crosslink between modified B27 and B29"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"5mhd",
- "title":"Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions."},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"6ver",
+ "resolution":1.047,
+ "title":"Human insulin analog: [GluB10,TyrB20]-DOI"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"5mhd",
- "title":"Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions."},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"6ver",
+ "resolution":1.047,
+ "title":"Human insulin analog: [GluB10,TyrB20]-DOI"},
{
"experimental_method":["Solution NMR"],
"pdb_id":"2n2x",
"title":"Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5hqi",
- "resolution":0.97,
- "title":"Insulin with proline analog HzP at position B28 in the T2 state"},
+ "pdb_id":"4rxw",
+ "resolution":1.73,
+ "title":"Crystal Structure of the cobalt human insulin derivative"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5hqi",
- "resolution":0.97,
- "title":"Insulin with proline analog HzP at position B28 in the T2 state"},
+ "pdb_id":"4rxw",
+ "resolution":1.73,
+ "title":"Crystal Structure of the cobalt human insulin derivative"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4eww",
- "resolution":2.3,
- "title":"Human Insulin"},
+ "pdb_id":"5bts",
+ "resolution":1.77,
+ "title":"Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"5bts",
+ "resolution":1.77,
+ "title":"Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2ws1",
+ "resolution":1.6,
+ "title":"Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2ws1",
+ "resolution":1.6,
+ "title":"Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"2wru",
"title":"Semi-synthetic highly active analogue of human insulin NMeAlaB26-DTI- NH2"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1a",
- "resolution":1.8,
+ "pdb_id":"4f1f",
+ "resolution":1.684,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1a",
- "resolution":1.8,
- "title":"Human Insulin"},
+ "pdb_id":"4f1g",
+ "resolution":1.637,
+ "title":"Human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f51",
- "resolution":1.637,
+ "pdb_id":"4f0o",
+ "resolution":1.672,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f4t",
- "resolution":1.637,
+ "pdb_id":"4f1c",
+ "resolution":1.7,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f0o",
- "resolution":1.672,
+ "pdb_id":"4f1b",
+ "resolution":1.591,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2ws1",
- "resolution":1.6,
- "title":"Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form"},
+ "pdb_id":"4ex0",
+ "resolution":1.86,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2ws1",
- "resolution":1.6,
- "title":"Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form"},
+ "pdb_id":"4ex0",
+ "resolution":1.86,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4fka",
- "resolution":1.08,
- "title":"High resolution structure of the manganese derivative of insulin"},
+ "pdb_id":"4eww",
+ "resolution":2.3,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1g",
+ "pdb_id":"4f4v",
"resolution":1.637,
- "title":"Human insulin"},
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f8f",
- "resolution":1.676,
+ "pdb_id":"4eyd",
+ "resolution":1.471,
+ "title":"Human Insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4eyd",
+ "resolution":1.471,
+ "title":"Human Insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4eyp",
+ "resolution":1.591,
+ "title":"Human Insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4eyn",
+ "resolution":1.532,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f0n",
- "resolution":1.679,
+ "pdb_id":"4eyn",
+ "resolution":1.532,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f0n",
- "resolution":1.679,
+ "pdb_id":"4ex1",
+ "resolution":1.657,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1b",
- "resolution":1.591,
+ "pdb_id":"4ey1",
+ "resolution":1.471,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1c",
- "resolution":1.7,
+ "pdb_id":"4f51",
+ "resolution":1.637,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1f",
- "resolution":1.684,
+ "pdb_id":"4f4t",
+ "resolution":1.637,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f4v",
- "resolution":1.637,
+ "pdb_id":"4ewz",
+ "resolution":1.791,
"title":"Human Insulin"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"1aiy",
- "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4ewx",
+ "resolution":2.201,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1htv",
- "resolution":1.9,
- "title":"CRYSTAL STRUCTURE OF DESTRIPEPTIDE (B28-B30) INSULIN"},
+ "pdb_id":"4ey9",
+ "resolution":1.471,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1htv",
- "resolution":1.9,
- "title":"CRYSTAL STRUCTURE OF DESTRIPEPTIDE (B28-B30) INSULIN"},
+ "pdb_id":"4ey9",
+ "resolution":1.471,
+ "title":"Human Insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4exx",
+ "resolution":1.55,
+ "title":"Human Insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4exx",
+ "resolution":1.55,
+ "title":"Human Insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4ewz",
+ "resolution":1.791,
+ "title":"Human Insulin"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1ai0",
- "title":"R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES"},
+ "pdb_id":"1aiy",
+ "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"1ai0",
- "title":"R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES"},
+ "pdb_id":"1aiy",
+ "title":"R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"3bxq",
"title":"Non-standard Design of Unstable Insulin Analogues with Enhanced Activity"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2kqq",
- "title":"NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures"},
+ "pdb_id":"1ai0",
+ "title":"R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES"},
{
"experimental_method":["Solution NMR"],
- "pdb_id":"2l1y",
- "title":"NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6ver",
- "resolution":1.047,
- "title":"Human insulin analog: [GluB10,TyrB20]-DOI"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6ver",
- "resolution":1.047,
- "title":"Human insulin analog: [GluB10,TyrB20]-DOI"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5bts",
- "resolution":1.77,
- "title":"Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5bts",
- "resolution":1.77,
- "title":"Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin"},
+ "pdb_id":"1ai0",
+ "title":"R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5bpo",
+ "pdb_id":"1htv",
"resolution":1.9,
- "title":"Human insulin with intra-chain chemical crosslink between modified B27 and B29"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5urt",
- "resolution":1.18,
- "title":"Insulin with proline analog DhP at position B28 in the T2 state"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5usp",
- "resolution":1.174,
- "title":"Insulin with proline analog Pip at position B28 in the T2 state"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5usp",
- "resolution":1.174,
- "title":"Insulin with proline analog Pip at position B28 in the T2 state"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6h3m",
- "resolution":1.821,
- "title":"The crystal structure of a human seleno-insulin analog"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6h3m",
- "resolution":1.821,
- "title":"The crystal structure of a human seleno-insulin analog"},
+ "title":"CRYSTAL STRUCTURE OF DESTRIPEPTIDE (B28-B30) INSULIN"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4rxw",
- "resolution":1.73,
- "title":"Crystal Structure of the cobalt human insulin derivative"},
+ "pdb_id":"1htv",
+ "resolution":1.9,
+ "title":"CRYSTAL STRUCTURE OF DESTRIPEPTIDE (B28-B30) INSULIN"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4rxw",
- "resolution":1.73,
- "title":"Crystal Structure of the cobalt human insulin derivative"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2n2v",
- "title":"Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 1.9"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2n2w",
- "title":"Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0"},
+ "pdb_id":"4f8f",
+ "resolution":1.676,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4eyd",
- "resolution":1.471,
+ "pdb_id":"4f0n",
+ "resolution":1.679,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4eyd",
- "resolution":1.471,
+ "pdb_id":"4f0n",
+ "resolution":1.679,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4eyn",
- "resolution":1.532,
- "title":"Human Insulin"},
+ "pdb_id":"4fka",
+ "resolution":1.08,
+ "title":"High resolution structure of the manganese derivative of insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4eyn",
- "resolution":1.532,
+ "pdb_id":"4f1a",
+ "resolution":1.8,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ey1",
- "resolution":1.471,
+ "pdb_id":"4f1a",
+ "resolution":1.8,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ewx",
- "resolution":2.201,
- "title":"Human Insulin"},
+ "pdb_id":"6h3m",
+ "resolution":1.821,
+ "title":"The crystal structure of a human seleno-insulin analog"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4eyp",
- "resolution":1.591,
- "title":"Human Insulin"},
+ "pdb_id":"6h3m",
+ "resolution":1.821,
+ "title":"The crystal structure of a human seleno-insulin analog"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4exx",
- "resolution":1.55,
- "title":"Human Insulin"},
+ "pdb_id":"5c0d",
+ "resolution":1.68,
+ "title":"HLA-A02 carrying AQWGPDPAAA"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4exx",
- "resolution":1.55,
- "title":"Human Insulin"},
+ "pdb_id":"4iuz",
+ "resolution":1.6,
+ "title":"High resolution crystal structure of racemic ester insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5usv",
- "resolution":1.3,
- "title":"Insulin with proline analog AzeP at position B28 in the T2 state"},
+ "pdb_id":"5urt",
+ "resolution":1.18,
+ "title":"Insulin with proline analog DhP at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5usv",
- "resolution":1.3,
- "title":"Insulin with proline analog AzeP at position B28 in the T2 state"},
+ "pdb_id":"5cny",
+ "resolution":1.7,
+ "title":"Crystal Structure of human zinc insulin at pH 5.5"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"5uu2",
"title":"Insulin with proline analog ThioP at position B28 in the T2 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ex1",
- "resolution":1.657,
- "title":"Human Insulin"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2n2x",
- "title":"Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9"},
+ "pdb_id":"3exx",
+ "resolution":1.35,
+ "title":"Structure of the T6 human insulin derivative with nickel at 1.35 A resolution"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ey9",
- "resolution":1.471,
- "title":"Human Insulin"},
+ "pdb_id":"2vjz",
+ "resolution":1.8,
+ "title":"Crystal structure form ultalente insulin microcrystals"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ey9",
- "resolution":1.471,
- "title":"Human Insulin"},
+ "pdb_id":"4cxl",
+ "resolution":1.5,
+ "title":"Human insulin analogue (D-ProB8)-insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3q6e",
- "resolution":2.05,
- "title":"Human insulin in complex with cucurbit[7]uril"},
+ "pdb_id":"4cxl",
+ "resolution":1.5,
+ "title":"Human insulin analogue (D-ProB8)-insulin"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3q6e",
- "resolution":2.05,
- "title":"Human insulin in complex with cucurbit[7]uril"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2mli",
+ "title":"NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ex0",
- "resolution":1.86,
- "title":"Human Insulin"},
+ "pdb_id":"5bpo",
+ "resolution":1.9,
+ "title":"Human insulin with intra-chain chemical crosslink between modified B27 and B29"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ex0",
- "resolution":1.86,
- "title":"Human Insulin"},
+ "pdb_id":"2wrv",
+ "resolution":2.15,
+ "title":"Semi-synthetic highly active analogue of human insulin NMeHisB26-DTI- NH2"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4eww",
- "resolution":2.3,
- "title":"Human Insulin"},
+ "pdb_id":"2wrv",
+ "resolution":2.15,
+ "title":"Semi-synthetic highly active analogue of human insulin NMeHisB26-DTI- NH2"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ewz",
- "resolution":1.791,
- "title":"Human Insulin"},
+ "pdb_id":"3exx",
+ "resolution":1.35,
+ "title":"Structure of the T6 human insulin derivative with nickel at 1.35 A resolution"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ewz",
- "resolution":1.791,
+ "pdb_id":"4f1f",
+ "resolution":1.684,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5c0d",
- "resolution":1.68,
- "title":"HLA-A02 carrying AQWGPDPAAA"},
+ "pdb_id":"4f1g",
+ "resolution":1.637,
+ "title":"Human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3ir0",
- "resolution":2.2,
- "title":"Crystal Structure of Human Insulin complexed with Cu+2 metal ion"},
+ "pdb_id":"4f0o",
+ "resolution":1.672,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3ir0",
- "resolution":2.2,
- "title":"Crystal Structure of Human Insulin complexed with Cu+2 metal ion"},
+ "pdb_id":"4f1c",
+ "resolution":1.7,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3exx",
- "resolution":1.35,
- "title":"Structure of the T6 human insulin derivative with nickel at 1.35 A resolution"},
+ "pdb_id":"4f1b",
+ "resolution":1.591,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3exx",
- "resolution":1.35,
- "title":"Structure of the T6 human insulin derivative with nickel at 1.35 A resolution"},
+ "pdb_id":"4f4v",
+ "resolution":1.637,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2wrv",
- "resolution":2.15,
- "title":"Semi-synthetic highly active analogue of human insulin NMeHisB26-DTI- NH2"},
+ "pdb_id":"2vk0",
+ "resolution":2.2,
+ "title":"Crystal structure form ultalente insulin microcrystals"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2wrv",
- "resolution":2.15,
- "title":"Semi-synthetic highly active analogue of human insulin NMeHisB26-DTI- NH2"},
+ "pdb_id":"4eyp",
+ "resolution":1.591,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2vk0",
- "resolution":2.2,
- "title":"Crystal structure form ultalente insulin microcrystals"},
+ "pdb_id":"4f1d",
+ "resolution":1.637,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1b9e",
- "resolution":2.5,
- "title":"HUMAN INSULIN MUTANT SERB9GLU"},
+ "pdb_id":"4gbc",
+ "resolution":1.778,
+ "title":"Crystal structure of aspart insulin at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1b9e",
- "resolution":2.5,
- "title":"HUMAN INSULIN MUTANT SERB9GLU"},
+ "pdb_id":"4ex1",
+ "resolution":1.657,
+ "title":"Human Insulin"},
{
- "experimental_method":["X-ray powder diffraction"],
- "pdb_id":"1fub",
- "title":"FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4ey1",
+ "resolution":1.471,
+ "title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"4f51",
"resolution":1.637,
"title":"Human Insulin"},
{
+ "experimental_method":["X-ray powder diffraction"],
+ "pdb_id":"1fub",
+ "title":"FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA"},
+ {
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f0o",
- "resolution":1.672,
- "title":"Human Insulin"},
+ "pdb_id":"3bxq",
+ "resolution":1.3,
+ "title":"The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2vjz",
- "resolution":1.8,
- "title":"Crystal structure form ultalente insulin microcrystals"},
+ "pdb_id":"1jca",
+ "resolution":2.5,
+ "title":"Non-standard Design of Unstable Insulin Analogues with Enhanced Activity"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4fka",
- "resolution":1.08,
- "title":"High resolution structure of the manganese derivative of insulin"},
+ "pdb_id":"1b9e",
+ "resolution":2.5,
+ "title":"HUMAN INSULIN MUTANT SERB9GLU"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1g",
- "resolution":1.637,
- "title":"Human insulin"},
+ "pdb_id":"1b9e",
+ "resolution":2.5,
+ "title":"HUMAN INSULIN MUTANT SERB9GLU"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"2r36",
"title":"Crystal structure of ni human ARG-insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4gbi",
- "resolution":2.502,
- "title":"Crystal structure of aspart insulin at pH 6.5"},
+ "pdb_id":"2ceu",
+ "resolution":1.8,
+ "title":"Despentapeptide insulin in acetic acid (pH 2)"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f8f",
- "resolution":1.676,
- "title":"Human Insulin"},
+ "pdb_id":"2ceu",
+ "resolution":1.8,
+ "title":"Despentapeptide insulin in acetic acid (pH 2)"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1d",
- "resolution":1.637,
- "title":"Human Insulin"},
+ "pdb_id":"3ir0",
+ "resolution":2.2,
+ "title":"Crystal Structure of Human Insulin complexed with Cu+2 metal ion"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4gbc",
- "resolution":1.778,
- "title":"Crystal structure of aspart insulin at pH 6.5"},
+ "pdb_id":"3ir0",
+ "resolution":2.2,
+ "title":"Crystal Structure of Human Insulin complexed with Cu+2 metal ion"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4gbn",
- "resolution":1.872,
+ "pdb_id":"4gbi",
+ "resolution":2.502,
"title":"Crystal structure of aspart insulin at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4cxl",
- "resolution":1.5,
- "title":"Human insulin analogue (D-ProB8)-insulin"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4cxl",
- "resolution":1.5,
- "title":"Human insulin analogue (D-ProB8)-insulin"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1b",
- "resolution":1.591,
+ "pdb_id":"4f8f",
+ "resolution":1.676,
"title":"Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1c",
- "resolution":1.7,
- "title":"Human Insulin"},
+ "pdb_id":"4gbn",
+ "resolution":1.872,
+ "title":"Crystal structure of aspart insulin at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4f1f",
- "resolution":1.684,
- "title":"Human Insulin"},
+ "pdb_id":"4fka",
+ "resolution":1.08,
+ "title":"High resolution structure of the manganese derivative of insulin"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4f4v",
- "resolution":1.637,
- "title":"Human Insulin"},
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7pg3",
+ "resolution":7.3,
+ "title":"Low resolution Cryo-EM structure of the full-length insulin receptor bound to 3 insulin, conf 2"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7pg3",
+ "resolution":7.3,
+ "title":"Low resolution Cryo-EM structure of the full-length insulin receptor bound to 3 insulin, conf 2"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7pg0",
+ "resolution":7.6,
+ "title":"Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin with visible ddm micelle, conf 1"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7pg0",
+ "resolution":7.6,
+ "title":"Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin with visible ddm micelle, conf 1"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7pg2",
+ "resolution":6.7,
+ "title":"Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin, conf 1"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7pg2",
+ "resolution":6.7,
+ "title":"Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin, conf 1"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7pg4",
+ "resolution":9.1,
+ "title":"Low resolution Cryo-EM structure of the full-length insulin receptor bound to 2 insulin, conf 3"},
+ {
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7pg4",
+ "resolution":9.1,
+ "title":"Low resolution Cryo-EM structure of the full-length insulin receptor bound to 2 insulin, conf 3"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2ceu",
- "resolution":1.8,
- "title":"Despentapeptide insulin in acetic acid (pH 2)"},
+ "pdb_id":"5co9",
+ "resolution":1.92,
+ "title":"Crystal structure of human zinc insulin at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2ceu",
- "resolution":1.8,
- "title":"Despentapeptide insulin in acetic acid (pH 2)"},
+ "pdb_id":"5co2",
+ "resolution":1.7,
+ "title":"Crystalization of human zinc insulin at pH 5.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3bxq",
- "resolution":1.3,
- "title":"The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition"},
+ "pdb_id":"5co2",
+ "resolution":1.7,
+ "title":"Crystalization of human zinc insulin at pH 5.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1jca",
- "resolution":2.5,
- "title":"Non-standard Design of Unstable Insulin Analogues with Enhanced Activity"},
+ "pdb_id":"4iuz",
+ "resolution":1.6,
+ "title":"High resolution crystal structure of racemic ester insulin"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"5cny",
"title":"Crystal Structure of human zinc insulin at pH 5.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5bpo",
- "resolution":1.9,
- "title":"Human insulin with intra-chain chemical crosslink between modified B27 and B29"},
+ "pdb_id":"4cy7",
+ "resolution":1.4,
+ "title":"Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form II"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5urt",
- "resolution":1.18,
- "title":"Insulin with proline analog DhP at position B28 in the T2 state"},
+ "pdb_id":"2vjz",
+ "resolution":1.8,
+ "title":"Crystal structure form ultalente insulin microcrystals"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"2mli",
- "title":"NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"6s4i",
+ "resolution":1.511,
+ "title":"Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4iuz",
- "resolution":1.6,
- "title":"High resolution crystal structure of racemic ester insulin"},
+ "pdb_id":"6s4i",
+ "resolution":1.511,
+ "title":"Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ey1",
- "resolution":1.471,
- "title":"Human Insulin"},
+ "pdb_id":"6p4z",
+ "resolution":1.8,
+ "title":"Structure of gadolinium-caged cobalt (III) insulin hexamer"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4eyp",
- "resolution":1.591,
- "title":"Human Insulin"},
+ "pdb_id":"5boq",
+ "resolution":1.7,
+ "title":"Human insulin with intra-chain chemical crosslink between modified B24 and B29"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5uu2",
- "resolution":1.223,
- "title":"Insulin with proline analog ThioP at position B28 in the T2 state"},
+ "pdb_id":"5boq",
+ "resolution":1.7,
+ "title":"Human insulin with intra-chain chemical crosslink between modified B24 and B29"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ex1",
- "resolution":1.657,
- "title":"Human Insulin"},
+ "pdb_id":"6vet",
+ "resolution":1.46,
+ "title":"Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"6vet",
+ "resolution":1.46,
+ "title":"Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"6gv0",
+ "resolution":1.26,
+ "title":"Insulin glulisine"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"2omi",
"title":"Enhancing the activity of insulin by stereospecific unfolding"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2g54",
- "resolution":2.25,
- "title":"Crystal structure of Zn-bound human insulin-degrading enzyme in complex with insulin B chain"},
+ "pdb_id":"4efx",
+ "resolution":1.98,
+ "title":"Highly biologically active insulin with additional disulfide bond"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4efx",
+ "resolution":1.98,
+ "title":"Highly biologically active insulin with additional disulfide bond"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"2vk0",
"resolution":2.2,
"title":"Crystal structure form ultalente insulin microcrystals"},
{
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"4gbc",
+ "resolution":1.778,
+ "title":"Crystal structure of aspart insulin at pH 6.5"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2g54",
+ "resolution":2.25,
+ "title":"Crystal structure of Zn-bound human insulin-degrading enzyme in complex with insulin B chain"},
+ {
"experimental_method":["X-ray powder diffraction"],
"pdb_id":"1fub",
"title":"FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA"},
{
+ "experimental_method":["X-ray powder diffraction"],
+ "pdb_id":"1fu2",
+ "title":"FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA"},
+ {
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2vjz",
- "resolution":1.8,
- "title":"Crystal structure form ultalente insulin microcrystals"},
+ "pdb_id":"1ev3",
+ "resolution":1.78,
+ "title":"Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2r36",
+ "pdb_id":"1j73",
"resolution":2.0,
- "title":"Crystal structure of ni human ARG-insulin"},
+ "title":"Crystal structure of an unstable insulin analog with native activity."},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4gbk",
- "resolution":2.4,
- "title":"Crystal structure of aspart insulin at pH 8.5"},
+ "pdb_id":"1j73",
+ "resolution":2.0,
+ "title":"Crystal structure of an unstable insulin analog with native activity."},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4gbk",
- "resolution":2.4,
- "title":"Crystal structure of aspart insulin at pH 8.5"},
+ "pdb_id":"2r36",
+ "resolution":2.0,
+ "title":"Crystal structure of ni human ARG-insulin"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"4gbi",
"title":"Crystal structure of aspart insulin at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4gbc",
- "resolution":1.778,
- "title":"Crystal structure of aspart insulin at pH 6.5"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4cy7",
- "resolution":1.4,
- "title":"Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form II"},
- {
- "experimental_method":["X-ray diffraction"],
"pdb_id":"4gbn",
"resolution":1.872,
"title":"Crystal structure of aspart insulin at pH 6.5"},
"resolution":2.5,
"title":"Crystal structure of aspart insulin at pH 8.5"},
{
- "experimental_method":["X-ray powder diffraction"],
- "pdb_id":"1fu2",
- "title":"FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA"},
- {
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1ev3",
- "resolution":1.78,
- "title":"Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer"},
+ "pdb_id":"4gbk",
+ "resolution":2.4,
+ "title":"Crystal structure of aspart insulin at pH 8.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1j73",
- "resolution":2.0,
- "title":"Crystal structure of an unstable insulin analog with native activity."},
+ "pdb_id":"4gbk",
+ "resolution":2.4,
+ "title":"Crystal structure of aspart insulin at pH 8.5"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"1j73",
- "resolution":2.0,
- "title":"Crystal structure of an unstable insulin analog with native activity."},
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"6ce7",
+ "resolution":7.4,
+ "title":"Insulin Receptor ectodomain in complex with one insulin molecule"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6s4i",
- "resolution":1.511,
- "title":"Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2jmn",
+ "title":"NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6s4i",
- "resolution":1.511,
- "title":"Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin"},
+ "experimental_method":["Solution NMR"],
+ "pdb_id":"2jmn",
+ "title":"NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6p4z",
- "resolution":1.8,
- "title":"Structure of gadolinium-caged cobalt (III) insulin hexamer"},
+ "pdb_id":"3utq",
+ "resolution":1.67,
+ "title":"Human HLA-A*0201-ALWGPDPAAA"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"5co9",
"title":"Crystal structure of human zinc insulin at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5cny",
- "resolution":1.7,
- "title":"Crystal Structure of human zinc insulin at pH 5.5"},
+ "pdb_id":"5co6",
+ "resolution":1.8,
+ "title":"Crystal structure of human zinc insulin at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5co2",
- "resolution":1.7,
- "title":"Crystalization of human zinc insulin at pH 5.5"},
+ "pdb_id":"5co6",
+ "resolution":1.8,
+ "title":"Crystal structure of human zinc insulin at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5co2",
- "resolution":1.7,
- "title":"Crystalization of human zinc insulin at pH 5.5"},
+ "pdb_id":"5ems",
+ "resolution":2.3,
+ "title":"Crystal Structure of an iodinated insulin analog"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5boq",
+ "pdb_id":"3e7z",
"resolution":1.7,
- "title":"Human insulin with intra-chain chemical crosslink between modified B24 and B29"},
+ "title":"Structure of human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5boq",
+ "pdb_id":"3e7z",
"resolution":1.7,
- "title":"Human insulin with intra-chain chemical crosslink between modified B24 and B29"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6vet",
- "resolution":1.46,
- "title":"Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6vet",
- "resolution":1.46,
- "title":"Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI"},
+ "title":"Structure of human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6gv0",
- "resolution":1.26,
- "title":"Insulin glulisine"},
+ "pdb_id":"3zu1",
+ "resolution":1.6,
+ "title":"Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4iuz",
+ "pdb_id":"3zu1",
"resolution":1.6,
- "title":"High resolution crystal structure of racemic ester insulin"},
+ "title":"Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4efx",
- "resolution":1.98,
- "title":"Highly biologically active insulin with additional disulfide bond"},
+ "pdb_id":"4cy7",
+ "resolution":1.4,
+ "title":"Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form II"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4efx",
- "resolution":1.98,
- "title":"Highly biologically active insulin with additional disulfide bond"},
- {
- "experimental_method":["Electron Microscopy"],
- "pdb_id":"6ce7",
- "resolution":7.4,
- "title":"Insulin Receptor ectodomain in complex with one insulin molecule"},
- {
- "experimental_method":["Solution NMR"],
- "pdb_id":"2jmn",
- "title":"NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures"},
+ "pdb_id":"6p4z",
+ "resolution":1.8,
+ "title":"Structure of gadolinium-caged cobalt (III) insulin hexamer"},
{
- "experimental_method":["Solution NMR"],
- "pdb_id":"2jmn",
- "title":"NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"6s4j",
+ "resolution":1.5,
+ "title":"Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3utq",
- "resolution":1.67,
- "title":"Human HLA-A*0201-ALWGPDPAAA"},
+ "pdb_id":"6s4j",
+ "resolution":1.5,
+ "title":"Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2omi",
- "resolution":2.24,
- "title":"Structure of human insulin cocrystallized with protamine"},
+ "pdb_id":"6gnq",
+ "resolution":2.2,
+ "title":"Monoclinic crystalline form of human insulin, complexed with meta-cresol"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3e7y",
- "resolution":1.6,
- "title":"Structure of human insulin"},
+ "pdb_id":"6gv0",
+ "resolution":1.26,
+ "title":"Insulin glulisine"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3e7y",
+ "pdb_id":"1uz9",
"resolution":1.6,
- "title":"Structure of human insulin"},
+ "title":"Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins."},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1ev6",
- "resolution":1.9,
- "title":"Structure of the monoclinic form of the M-cresol/insulin R6 hexamer"},
+ "pdb_id":"1uz9",
+ "resolution":1.6,
+ "title":"Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins."},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1trz",
- "resolution":1.6,
- "title":"CRYSTALLOGRAPHIC EVIDENCE FOR DUAL COORDINATION AROUND ZINC IN THE T3R3 HUMAN INSULIN HEXAMER"},
+ "pdb_id":"2omi",
+ "resolution":2.24,
+ "title":"Structure of human insulin cocrystallized with protamine"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1trz",
- "resolution":1.6,
- "title":"CRYSTALLOGRAPHIC EVIDENCE FOR DUAL COORDINATION AROUND ZINC IN THE T3R3 HUMAN INSULIN HEXAMER"},
+ "pdb_id":"2w44",
+ "resolution":2.0,
+ "title":"Structure DeltaA1-A4 insulin"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"2ws7",
"resolution":2.59,
"title":"Semi-synthetic analogue of human insulin ProB26-DTI"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4nib",
- "resolution":1.4,
- "title":"Crystal structure of human insulin mutant B20 D-ala, B23 D-ala"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4nib",
- "resolution":1.4,
- "title":"Crystal structure of human insulin mutant B20 D-ala, B23 D-ala"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"4cy7",
- "resolution":1.4,
- "title":"Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form II"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"1qj0",
- "resolution":2.4,
- "title":"HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR"},
- {
"experimental_method":["X-ray powder diffraction"],
"pdb_id":"1fu2",
"title":"FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1evr",
+ "pdb_id":"1ev6",
"resolution":1.9,
- "title":"The structure of the resorcinol/insulin R6 hexamer"},
+ "title":"Structure of the monoclinic form of the M-cresol/insulin R6 hexamer"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"1ev6",
"title":"Structure of the monoclinic form of the M-cresol/insulin R6 hexamer"},
{
"experimental_method":["X-ray diffraction"],
+ "pdb_id":"1ev3",
+ "resolution":1.78,
+ "title":"Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"1evr",
+ "resolution":1.9,
+ "title":"The structure of the resorcinol/insulin R6 hexamer"},
+ {
+ "experimental_method":["X-ray diffraction"],
"pdb_id":"1guj",
"resolution":1.62,
"title":"Insulin at pH 2: structural analysis of the conditions promoting insulin fibre formation."},
"title":"Insulin at pH 2: structural analysis of the conditions promoting insulin fibre formation."},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1ev3",
- "resolution":1.78,
- "title":"Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer"},
+ "pdb_id":"1trz",
+ "resolution":1.6,
+ "title":"CRYSTALLOGRAPHIC EVIDENCE FOR DUAL COORDINATION AROUND ZINC IN THE T3R3 HUMAN INSULIN HEXAMER"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2w44",
- "resolution":2.0,
- "title":"Structure DeltaA1-A4 insulin"},
+ "pdb_id":"1trz",
+ "resolution":1.6,
+ "title":"CRYSTALLOGRAPHIC EVIDENCE FOR DUAL COORDINATION AROUND ZINC IN THE T3R3 HUMAN INSULIN HEXAMER"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1uz9",
- "resolution":1.6,
- "title":"Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins."},
+ "pdb_id":"1qj0",
+ "resolution":2.4,
+ "title":"HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1uz9",
+ "pdb_id":"3e7y",
"resolution":1.6,
- "title":"Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins."},
+ "title":"Structure of human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3e7z",
- "resolution":1.7,
+ "pdb_id":"3e7y",
+ "resolution":1.6,
"title":"Structure of human insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3e7z",
- "resolution":1.7,
- "title":"Structure of human insulin"},
+ "pdb_id":"4nib",
+ "resolution":1.4,
+ "title":"Crystal structure of human insulin mutant B20 D-ala, B23 D-ala"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6gnq",
- "resolution":2.2,
- "title":"Monoclinic crystalline form of human insulin, complexed with meta-cresol"},
+ "pdb_id":"4nib",
+ "resolution":1.4,
+ "title":"Crystal structure of human insulin mutant B20 D-ala, B23 D-ala"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"7s4y",
"resolution":1.71,
"title":"Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - Insulin"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5co6",
- "resolution":1.8,
- "title":"Crystal structure of human zinc insulin at pH 6.5"},
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"6ce7",
+ "resolution":7.4,
+ "title":"Insulin Receptor ectodomain in complex with one insulin molecule"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5co6",
- "resolution":1.8,
- "title":"Crystal structure of human zinc insulin at pH 6.5"},
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"6hn5",
+ "resolution":3.2,
+ "title":"Leucine-zippered human insulin receptor ectodomain with single bound insulin - \"upper\" membrane-distal part"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6p4z",
- "resolution":1.8,
- "title":"Structure of gadolinium-caged cobalt (III) insulin hexamer"},
+ "pdb_id":"1jk8",
+ "resolution":2.4,
+ "title":"Crystal structure of a human insulin peptide-HLA-DQ8 complex"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5co9",
- "resolution":1.92,
- "title":"Crystal structure of human zinc insulin at pH 6.5"},
+ "pdb_id":"2wby",
+ "resolution":2.6,
+ "title":"Crystal structure of human insulin-degrading enzyme in complex with insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6s4j",
- "resolution":1.5,
- "title":"Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin"},
+ "pdb_id":"2wby",
+ "resolution":2.6,
+ "title":"Crystal structure of human insulin-degrading enzyme in complex with insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6s4j",
- "resolution":1.5,
- "title":"Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin"},
+ "pdb_id":"4ajx",
+ "resolution":1.2,
+ "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6gv0",
- "resolution":1.26,
- "title":"Insulin glulisine"},
+ "pdb_id":"4ajx",
+ "resolution":1.2,
+ "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3zu1",
- "resolution":1.6,
- "title":"Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin"},
+ "pdb_id":"4akj",
+ "resolution":2.01,
+ "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3zu1",
- "resolution":1.6,
- "title":"Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin"},
+ "pdb_id":"4ajz",
+ "resolution":1.8,
+ "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"5ems",
"resolution":2.3,
"title":"Crystal Structure of an iodinated insulin analog"},
{
- "experimental_method":["Electron Microscopy"],
- "pdb_id":"6ce7",
- "resolution":7.4,
- "title":"Insulin Receptor ectodomain in complex with one insulin molecule"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"5uss",
+ "resolution":2.061,
+ "title":"Insulin with proline analog PiP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1jk8",
- "resolution":2.4,
- "title":"Crystal structure of a human insulin peptide-HLA-DQ8 complex"},
+ "pdb_id":"5uss",
+ "resolution":2.061,
+ "title":"Insulin with proline analog PiP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2wby",
- "resolution":2.6,
- "title":"Crystal structure of human insulin-degrading enzyme in complex with insulin"},
+ "pdb_id":"5mt3",
+ "resolution":2.02,
+ "title":"Human insulin in complex with serotonin and arginine"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2wby",
- "resolution":2.6,
- "title":"Crystal structure of human insulin-degrading enzyme in complex with insulin"},
+ "pdb_id":"5uu3",
+ "resolution":2.25,
+ "title":"Insulin with proline analog DfP at position B28 in the R6 state"},
{
- "experimental_method":["Electron Microscopy"],
- "pdb_id":"6hn5",
- "resolution":3.2,
- "title":"Leucine-zippered human insulin receptor ectodomain with single bound insulin - \"upper\" membrane-distal part"},
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"5hrq",
+ "resolution":1.28,
+ "title":"Insulin with proline analog HzP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2om1",
- "resolution":1.97,
- "title":"Structure of human insulin in presence of thiocyanate at pH 6.5"},
+ "pdb_id":"5uru",
+ "resolution":2.41,
+ "title":"Insulin with proline analog DhP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2om0",
- "resolution":2.05,
- "title":"Structure of human insulin in presence of urea at pH 6.5"},
+ "pdb_id":"5hpr",
+ "resolution":1.33,
+ "title":"Insulin with proline analog HyP at position B28 in the T2 state"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"5hpr",
+ "resolution":1.33,
+ "title":"Insulin with proline analog HyP at position B28 in the T2 state"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"5udp",
+ "resolution":1.348,
+ "title":"High resolution x-ray crystal structure of synthetic insulin lispro"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2om0",
- "resolution":2.05,
- "title":"Structure of human insulin in presence of urea at pH 6.5"},
+ "pdb_id":"5udp",
+ "resolution":1.348,
+ "title":"High resolution x-ray crystal structure of synthetic insulin lispro"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3p33",
- "resolution":2.3,
- "title":"Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity"},
+ "pdb_id":"5mt9",
+ "resolution":1.88,
+ "title":"Human insulin in complex with serotonin and arginine"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2omg",
- "resolution":1.52,
- "title":"Structure of human insulin cocrystallized with protamine and urea"},
+ "pdb_id":"3zqr",
+ "resolution":1.9,
+ "title":"NMePheB25 insulin analogue crystal structure"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2olz",
- "resolution":1.7,
- "title":"Structure of human insulin in presence of thiocyanate at pH 7.0"},
+ "pdb_id":"3zqr",
+ "resolution":1.9,
+ "title":"NMePheB25 insulin analogue crystal structure"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2olz",
- "resolution":1.7,
- "title":"Structure of human insulin in presence of thiocyanate at pH 7.0"},
+ "pdb_id":"3kq6",
+ "resolution":1.9,
+ "title":"Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1ben",
- "resolution":1.4,
- "title":"INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE"},
+ "pdb_id":"3kq6",
+ "resolution":1.9,
+ "title":"Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1g7a",
- "resolution":1.2,
- "title":"1.2 A structure of T3R3 human insulin at 100 K"},
+ "pdb_id":"6nwv",
+ "resolution":1.601,
+ "title":"Insulin Lispro Analog"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1g7a",
- "resolution":1.2,
- "title":"1.2 A structure of T3R3 human insulin at 100 K"},
+ "pdb_id":"6gnq",
+ "resolution":2.2,
+ "title":"Monoclinic crystalline form of human insulin, complexed with meta-cresol"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"1w8p",
"title":"Structural properties of the B25Tyr-NMe-B26Phe insulin mutant."},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1rwe",
- "resolution":1.8,
- "title":"Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"1rwe",
- "resolution":1.8,
- "title":"Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues"},
- {
- "experimental_method":["X-ray diffraction"],
"pdb_id":"1znj",
"resolution":2.0,
"title":"INSULIN, MONOCLINIC CRYSTAL FORM"},
"title":"INSULIN, MONOCLINIC CRYSTAL FORM"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1xw7",
+ "pdb_id":"3p33",
"resolution":2.3,
- "title":"Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama"},
+ "title":"Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1xw7",
- "resolution":2.3,
- "title":"Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama"},
+ "pdb_id":"2w44",
+ "resolution":2.0,
+ "title":"Structure DeltaA1-A4 insulin"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"2ws7",
+ "resolution":2.59,
+ "title":"Semi-synthetic analogue of human insulin ProB26-DTI"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3v1g",
+ "resolution":2.2,
+ "title":"Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3v1g",
+ "resolution":2.2,
+ "title":"Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"4fg3",
"title":"Crystal Structure Analysis of the Human Insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2ws7",
- "resolution":2.59,
- "title":"Semi-synthetic analogue of human insulin ProB26-DTI"},
+ "pdb_id":"3v19",
+ "resolution":2.0,
+ "title":"Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"3v19",
+ "resolution":2.0,
+ "title":"Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"1lph",
"title":"LYS(B28)PRO(B29)-HUMAN INSULIN"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1qj0",
- "resolution":2.4,
- "title":"HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR"},
+ "pdb_id":"1g7a",
+ "resolution":1.2,
+ "title":"1.2 A structure of T3R3 human insulin at 100 K"},
+ {
+ "experimental_method":["X-ray diffraction"],
+ "pdb_id":"1g7a",
+ "resolution":1.2,
+ "title":"1.2 A structure of T3R3 human insulin at 100 K"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"1g7b",
"title":"The structure of the resorcinol/insulin R6 hexamer"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2w44",
- "resolution":2.0,
- "title":"Structure DeltaA1-A4 insulin"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"6gnq",
- "resolution":2.2,
- "title":"Monoclinic crystalline form of human insulin, complexed with meta-cresol"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5uru",
- "resolution":2.41,
- "title":"Insulin with proline analog DhP at position B28 in the R6 state"},
- {
- "experimental_method":["Electron Microscopy"],
- "pdb_id":"7bw7",
- "resolution":4.1,
- "title":"Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin."},
+ "pdb_id":"1ben",
+ "resolution":1.4,
+ "title":"INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6ck2",
- "resolution":2.25,
- "title":"Insulin analog containing a YB26W mutation"},
+ "pdb_id":"1xw7",
+ "resolution":2.3,
+ "title":"Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6nwv",
- "resolution":1.601,
- "title":"Insulin Lispro Analog"},
+ "pdb_id":"1xw7",
+ "resolution":2.3,
+ "title":"Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5hrq",
- "resolution":1.28,
- "title":"Insulin with proline analog HzP at position B28 in the R6 state"},
+ "pdb_id":"1rwe",
+ "resolution":1.8,
+ "title":"Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3zqr",
- "resolution":1.9,
- "title":"NMePheB25 insulin analogue crystal structure"},
+ "pdb_id":"1rwe",
+ "resolution":1.8,
+ "title":"Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3zqr",
- "resolution":1.9,
- "title":"NMePheB25 insulin analogue crystal structure"},
+ "pdb_id":"1qj0",
+ "resolution":2.4,
+ "title":"HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ajx",
- "resolution":1.2,
- "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
+ "pdb_id":"2om1",
+ "resolution":1.97,
+ "title":"Structure of human insulin in presence of thiocyanate at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ajx",
- "resolution":1.2,
- "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
+ "pdb_id":"2om0",
+ "resolution":2.05,
+ "title":"Structure of human insulin in presence of urea at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4akj",
- "resolution":2.01,
- "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
+ "pdb_id":"2om0",
+ "resolution":2.05,
+ "title":"Structure of human insulin in presence of urea at pH 6.5"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4ajz",
- "resolution":1.8,
- "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
+ "pdb_id":"2omg",
+ "resolution":1.52,
+ "title":"Structure of human insulin cocrystallized with protamine and urea"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3v19",
- "resolution":2.0,
- "title":"Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health"},
+ "pdb_id":"2olz",
+ "resolution":1.7,
+ "title":"Structure of human insulin in presence of thiocyanate at pH 7.0"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3v19",
- "resolution":2.0,
- "title":"Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health"},
+ "pdb_id":"2olz",
+ "resolution":1.7,
+ "title":"Structure of human insulin in presence of thiocyanate at pH 7.0"},
{
"experimental_method":["X-ray diffraction"],
"pdb_id":"3zs2",
"experimental_method":["X-ray diffraction"],
"pdb_id":"3zs2",
"resolution":1.97,
- "title":"TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3v1g",
- "resolution":2.2,
- "title":"Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3v1g",
- "resolution":2.2,
- "title":"Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5uu3",
- "resolution":2.25,
- "title":"Insulin with proline analog DfP at position B28 in the R6 state"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5uss",
- "resolution":2.061,
- "title":"Insulin with proline analog PiP at position B28 in the R6 state"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5uss",
- "resolution":2.061,
- "title":"Insulin with proline analog PiP at position B28 in the R6 state"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5udp",
- "resolution":1.348,
- "title":"High resolution x-ray crystal structure of synthetic insulin lispro"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5udp",
- "resolution":1.348,
- "title":"High resolution x-ray crystal structure of synthetic insulin lispro"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5mt9",
- "resolution":1.88,
- "title":"Human insulin in complex with serotonin and arginine"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5ems",
- "resolution":2.3,
- "title":"Crystal Structure of an iodinated insulin analog"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5hpr",
- "resolution":1.33,
- "title":"Insulin with proline analog HyP at position B28 in the T2 state"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"5hpr",
- "resolution":1.33,
- "title":"Insulin with proline analog HyP at position B28 in the T2 state"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3kq6",
- "resolution":1.9,
- "title":"Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog"},
+ "title":"TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3kq6",
- "resolution":1.9,
- "title":"Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog"},
+ "pdb_id":"6ck2",
+ "resolution":2.25,
+ "title":"Insulin analog containing a YB26W mutation"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5mt3",
- "resolution":2.02,
- "title":"Human insulin in complex with serotonin and arginine"},
+ "pdb_id":"4wdi",
+ "resolution":2.313,
+ "title":"Weak TCR binding to an unstable insulin epitope drives type 1 diabetes"},
{
"experimental_method":["Electron Microscopy"],
"pdb_id":"6hn5",
"title":"Leucine-zippered human insulin receptor ectodomain with single bound insulin - \"upper\" membrane-distal part"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4wdi",
- "resolution":2.313,
- "title":"Weak TCR binding to an unstable insulin epitope drives type 1 diabetes"},
- {
- "experimental_method":["X-ray diffraction"],
"pdb_id":"2wc0",
"resolution":2.8,
"title":"crystal structure of human insulin degrading enzyme in complex with iodinated insulin"},
"resolution":2.8,
"title":"crystal structure of human insulin degrading enzyme in complex with iodinated insulin"},
{
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"6sof",
+ "resolution":4.3,
+ "title":"human insulin receptor ectodomain bound by 4 insulin"},
+ {
"experimental_method":["X-ray diffraction"],
"pdb_id":"6z7y",
"resolution":2.2,
"title":"Human insulin in complex with the analytical antibody OXI-005 Fab"},
{
"experimental_method":["Electron Microscopy"],
- "pdb_id":"6sof",
- "resolution":4.3,
- "title":"human insulin receptor ectodomain bound by 4 insulin"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3p2x",
- "resolution":2.0,
- "title":"Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3p2x",
- "resolution":2.0,
- "title":"Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3jsd",
- "resolution":2.5,
- "title":"Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3jsd",
- "resolution":2.5,
- "title":"Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"2om1",
- "resolution":1.97,
- "title":"Structure of human insulin in presence of thiocyanate at pH 6.5"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"2omh",
- "resolution":1.36,
- "title":"Structure of human insulin cocrystallized with ARG-12 peptide in presence of urea"},
- {
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"2omh",
- "resolution":1.36,
- "title":"Structure of human insulin cocrystallized with ARG-12 peptide in presence of urea"},
+ "pdb_id":"7qid",
+ "resolution":5.0,
+ "title":"tentative model of the human insulin receptor ectodomain bound by three insulin"},
{
- "experimental_method":["X-ray diffraction"],
- "pdb_id":"3fq9",
- "resolution":1.35,
- "title":"Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications"},
+ "experimental_method":["Electron Microscopy"],
+ "pdb_id":"7qid",
+ "resolution":5.0,
+ "title":"tentative model of the human insulin receptor ectodomain bound by three insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3fq9",
- "resolution":1.35,
- "title":"Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications"},
+ "pdb_id":"4akj",
+ "resolution":2.01,
+ "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"3p33",
- "resolution":2.3,
- "title":"Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity"},
+ "pdb_id":"5mam",
+ "resolution":2.2,
+ "title":"Human insulin in complex with serotonin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2omg",
- "resolution":1.52,
- "title":"Structure of human insulin cocrystallized with protamine and urea"},
+ "pdb_id":"5mam",
+ "resolution":2.2,
+ "title":"Human insulin in complex with serotonin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1ben",
- "resolution":1.4,
- "title":"INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE"},
+ "pdb_id":"5mt3",
+ "resolution":2.02,
+ "title":"Human insulin in complex with serotonin and arginine"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1qiz",
- "resolution":2.0,
- "title":"HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH RESORCINOL"},
+ "pdb_id":"5uu3",
+ "resolution":2.25,
+ "title":"Insulin with proline analog DfP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1qiz",
- "resolution":2.0,
- "title":"HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH RESORCINOL"},
+ "pdb_id":"5uu4",
+ "resolution":1.973,
+ "title":"Insulin with proline analog ThioP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4p65",
- "resolution":1.5,
- "title":"Crystal structure of an cyclohexylalanine substituted insulin analog."},
+ "pdb_id":"5uu4",
+ "resolution":1.973,
+ "title":"Insulin with proline analog ThioP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"4p65",
- "resolution":1.5,
- "title":"Crystal structure of an cyclohexylalanine substituted insulin analog."},
+ "pdb_id":"5hrq",
+ "resolution":1.28,
+ "title":"Insulin with proline analog HzP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"1lph",
- "resolution":2.3,
- "title":"LYS(B28)PRO(B29)-HUMAN INSULIN"},
+ "pdb_id":"5uru",
+ "resolution":2.41,
+ "title":"Insulin with proline analog DhP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"2oly",
- "resolution":1.7,
- "title":"Structure of human insulin in presence of urea at pH 7.0"},
+ "pdb_id":"5mt9",
+ "resolution":1.88,
+ "title":"Human insulin in complex with serotonin and arginine"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6tyh",
- "resolution":1.600019,
- "title":"Four-Disulfide Insulin Analog A22/B22"},
+ "pdb_id":"4ajz",
+ "resolution":1.8,
+ "title":"Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6tyh",
- "resolution":1.600019,
- "title":"Four-Disulfide Insulin Analog A22/B22"},
+ "pdb_id":"5hpu",
+ "resolution":2.2,
+ "title":"Insulin with proline analog HyP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"5uru",
- "resolution":2.41,
- "title":"Insulin with proline analog DhP at position B28 in the R6 state"},
- {
- "experimental_method":["Electron Microscopy"],
- "pdb_id":"7bw8",
- "resolution":3.8,
- "title":"Cryo-EM Structure for the Insulin Binding Region in the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin"},
+ "pdb_id":"5hpu",
+ "resolution":2.2,
+ "title":"Insulin with proline analog HyP at position B28 in the R6 state"},
{
"experimental_method":["X-ray diffraction"],
- "pdb_id":"6ck2",
- "resolution":2.25,
- "title":"Insulin analog containing a YB26W mutation"},
+ "pdb_id":"6nwv",
+ "resolution":1.601,
+ "title":"Insulin Lispro Analog"},
{
"experimental_method":["Electron Microscopy"],
"pdb_id":"6bfc",
"title":"Cryo-EM structure of human insulin degrading enzyme in complex with insulin"},
{
"experimental_method":["Electron Microscopy"],
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