1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 MN-----------------GTE--GDNFYVP----FS---------------------NK
3 TGLARSPY----------------------EYPQY-YLAEPWK---------YSALAAYM
4 FFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GY
5 FV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIMGVAF
6 TWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHF
7 LVPFVIIFFCYGRLLCTV------------------------------------------
8 ------------------------------------------------------------
9 ---------------------KEAAAAQQ----------ESASTQKA-------------
10 ----------------EKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQGSD---FGATF
11 MTLPAFFAKSSALYNPVIYILMNKQFRNCMITT----LCCGKNPLGDDE--SGASTSKTE
12 VSS---------------------------------------------------------
13 --------------------------------VS-TSPVSP-A---
14 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
15 MN-----------------GTE--GPNFYVP----FS---------------------NI
16 TGVVRSPF----------------------EQPQY-YLAEPWQ---------FSMLAAYM
17 FLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GY
18 FV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGVAF
19 TWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHF
20 TIPMIVIFFCYGQLVFTV------------------------------------------
21 ------------------------------------------------------------
22 ---------------------KEAAAQQQ----------ESATTQKA-------------
23 ----------------EKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQGSN---FGPIF
24 MTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTS----LCCGKNPLGDDE--ASATASKTE
25 ------------------------------------------------------------
26 -----------------------------------TSQVAP-A---
27 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
28 MN-----------------GTE--GINFYVP----MS---------------------NK
29 TGVVRSPF----------------------EYPQY-YLAEPWK---------YRLVCCYI
30 FFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GY
31 FV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMMGIAF
32 TWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHF
33 IIPVVVIFFSYGRLICKV------------------------------------------
34 ------------------------------------------------------------
35 ---------------------REAAAQQQ----------ESATTQKA-------------
36 ----------------EKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKGAD---FTATL
37 MAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITT----ICCGKNPFGDEDVSSTVSQSKTE
38 VSS---------------------------------------------------------
39 --------------------------------VS-SSQVSP-A---
40 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
41 MN-----------------GTE--GKNFYVP----MS---------------------NR
42 TGLVRSPF----------------------EYPQY-YLAEPWQ---------FKILALYL
43 FFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GY
44 FV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFAGIAF
45 TWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHF
46 ILPVAVIFFTYGRLVCTV------------------------------------------
47 ------------------------------------------------------------
48 ---------------------KAAAAQQQ----------DSASTQKA-------------
49 ----------------EREVTKMVILMVFGFLIAWTPYATVAAWIFFNKGAD---FSAKF
50 MAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTT----IFCGKNPLGDDE-SSTVSTSKTE
51 VSS---------------------------------------------------------
52 --------------------------------------VSP-A---
53 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
54 MN-----------------GTE--GNNFYVP----LS---------------------NR
55 TGLVRSPF----------------------EYPQY-YLAEPWQ---------FKLLAVYM
56 FFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GY
57 FA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASAGIAF
58 TWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHF
59 ILPVTIIFFTYGRLVCTV------------------------------------------
60 ------------------------------------------------------------
61 ---------------------KAAAAQQQ----------DSASTQKA-------------
62 ----------------EREVTKMVILMVLGFLVAWTPYATVAAWIFFNKGAA---FSAQF
63 MAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTT----LFCGKNPLGDEE-SSTVSTSKTE
64 VSS---------------------------------------------------------
65 --------------------------------------VSP-A---
66 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
67 MK-----------------QVPEFHEDFYIPIPLDIN---------------------NL
68 S--AYSPF----------------------LVPQD-HLGNQGI---------FMAMSVFM
69 FFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RY
70 FI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIAGCIL
71 PWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCF
72 AVPFGTIVFCYGQLLITL------------------------------------------
73 ------------------------------------------------------------
74 ---------------------KLAAKAQA----------DSASTQKA-------------
75 ----------------EREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRGEE---FDLRM
76 ATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-K----MVCGKN-IEEDE--ASTSSQVTQ
77 VSS---------------------------------------------------------
78 --------------------------------------VAPEK---
79 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
80 MR-----------------KMS--EEEFYL-----FK---------------------NI
81 SSV--GPW----------------------DGPQY-HIAPVWA---------FYLQAAFM
82 GTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GY
83 FV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALTVVLA
84 TWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCF
85 IVPLSLICFSYTQLLRAL------------------------------------------
86 ------------------------------------------------------------
87 ---------------------KAVAAQQQ----------ESATTQKA-------------
88 ----------------EREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHG---LDLRL
89 VTIPSFFSKSACIYNPIIYCFMNKQFQACIM-K----MVCGKA-MTDES--DTCSSQKTE
90 VST---------------------------------------------------------
91 --------------------------------VS-STQVGP-N---
92 > 8=opsin, greensensitive human (fragment) S07060
93 ------------------------------------------------------------
94 ------------------------------------------------------------
95 --------------------------------------DLAETVIA-STISIVNQVS-GY
96 FV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAF
97 SWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCC
98 ITPLSIIVLCYLQVWLAI------------------------------------------
99 ------------------------------------------------------------
100 ---------------------RAVAKQQK----------ESESTQKA-------------
101 ----------------EKEVTRMVVVMVLAFC----------------------------
102 ------------------------------------------------------------
103 ------------------------------------------------------------
104 ----------------------------------------------
105 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
106 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYT----NS---------------------NS
107 T---RGPF----------------------EGPNY-HIAPRWV---------YHLTSVWM
108 IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GY
109 FV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIVGIAF
110 SWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCC
111 ITPLSIIVLCYLQVWLAI------------------------------------------
112 ------------------------------------------------------------
113 ---------------------RAVAKQQK----------ESESTQKA-------------
114 ----------------EKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYP---FHPLM
115 AALPAFFAKSATIYNPVIYVFMNRQFRNCILQL----F-----GKKVDDGSELSSASKTE
116 VSS---------------------------------------------------------
117 --------------------------------V---SSVSP-A---
118 > 10== Z68193 1 human Red Opsin <>[]
119 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYT----NS---------------------NS
120 T---RGPF----------------------EGPNY-HIAPRWV---------YHLTSVWM
121 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GY
122 FV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAF
123 SWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCC
124 IIPLAIIMLCYLQVWLAI------------------------------------------
125 ------------------------------------------------------------
126 ---------------------RAVAKQQK----------ESESTQKA-------------
127 ----------------EKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYA---FHPLM
128 AALPAYFAKSATIYNPVIYVFMNRQFRNCILQL----F-----GKKVDDGSELSSASKTE
129 VSS---------------------------------------------------------
130 --------------------------------V---SSVSP-A---
131 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
132 MTEAWNVAVFAARRSRDD-DDTTRGSVFTYT----NT---------------------NN
133 T---RGPF----------------------EGPNY-HIAPRWV---------YNLVSFFM
134 IIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GY
135 FI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAIIGIVF
136 SWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCC
137 FLPLFIIIVCYLQVWMAI------------------------------------------
138 ------------------------------------------------------------
139 ---------------------RAVAAQQK----------ESESTQKA-------------
140 ----------------EREVSRMVVVMIVAFCICWGPYASFVSFAAANPGYA---FHPLA
141 AALPAYFAKSATIYNPVIYVFMNRQFRNCIMQL----F-----GKKVDDGSEASTTSRTE
142 VSS---------------------------------------------------------
143 --------------------------------VS-NSSVAP-A---
144 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
145 MAA-WEAAFAARRRHEE--EDTTRDSVFTYT----NS---------------------NN
146 T---RGPF----------------------EGPNY-HIAPRWV---------YNLTSVWM
147 IFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GY
148 FI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVAGILF
149 SWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCC
150 FFPLAIIILCYLQVWLAI------------------------------------------
151 ------------------------------------------------------------
152 ---------------------RAVAAQQK----------ESESTQKA-------------
153 ----------------EKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPGYA---FHPLA
154 AALPAYFAKSATIYNPIIYVFMNRQFRNCILQL----F-----GKKVDDGSEVST-SRTE
155 VSS---------------------------------------------------------
156 --------------------------------VS-NSSVSP-A---
157 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
158 MS-----------------SNSSQAP----------P---------------------NG
159 T---PGPF----------------------DGPQWPYQAPQST---------YVGVAVLM
160 GTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GF
161 FV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVSGCAF
162 TWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGSNN--NSYILSLFVTCF
163 VLPLSLILFSYTNLLLTL------------------------------------------
164 ------------------------------------------------------------
165 ---------------------RAAAAQQK----------EADTTQRA-------------
166 ----------------EREVTRMVIVMVMAFLLCWLPYSTFALVVATHKGII---IQPVL
167 ASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEM----LCCGYQPQRTGKASPGTPGPHAD
168 VTA---------------------------------------------------------
169 --------------------------------AGLRNKVMP-AHPV
170 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
171 MESGNVSSSLFGNVSTALRPEA----RLSA---E------------------------TR
172 LLGWNVPP----------------------EELR--HIPEHWLTYPEPPESMNYLLGTLY
173 IFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSFH-QG
174 YA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIF
175 IYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFVACIFFFSF
176 VCPTTMITYYYSQIVGHVFSH---------------------------------------
177 ------------------------------------------------------------
178 --------------------EKALRDQAKKMNVESLRSNVDKNKETA-------------
179 ----------------EIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKTL---LTPGA
180 TMIPACACKMVACIDPFVYAISHPRYRMELQKRCPW-LALNEKAPES----SAVASTSTT
181 QEP---------------------------------------------------------
182 ------------------------------------QQTTA-A---
183 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
184 MEYHNVSSVL-GNVSSVLRPDA----RLSA---E------------------------SR
185 LLGWNVPP----------------------DELR--HIPEHWLIYPEPPESMNYLLGTLY
186 IFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSFH-QG
187 YA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIF
188 IYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFVACIFFFSF
189 VCPTTMITYYYSQIVGHVFSH---------------------------------------
190 ------------------------------------------------------------
191 --------------------EKALRDQAKKMNVDSLRSNVDKSKEAA-------------
192 ----------------EIRIAKAAITICFLFFASWTPYGVMSLIGAFGDKTL---LTPGA
193 TMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPW-LAISEKAPES----RAAISTSTT
194 QEQ---------------------------------------------------------
195 ------------------------------------QQTTA-A---
196 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
197 ME------PLCNASEPPLRPEA----R-SSGNGD------------------------LQ
198 FLGWNVPP----------------------DQIQ--YIPEHWLTQLEPPASMHYMLGVFY
199 IFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSFH-RG
200 FAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNII
201 IWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFVGTIFFFSF
202 VCPTLMILYYYSQIVGHVFSH---------------------------------------
203 ------------------------------------------------------------
204 --------------------EKALREQAKKMNVESLRSNVDKSKETA-------------
205 ----------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSL---LTQGA
206 TMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPW-LGVNEKSGEI----SSAQSTTTQ
207 EQ----------------------------------------------------------
208 ------------------------------------QQTTA-A---
209 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
210 MD------ALCNASEPPLRPEA----RMSSGSDE------------------------LQ
211 FLGWNVPP----------------------DQIQ--YIPEHWLTQLEPPASMHYMLGVFY
212 IFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSFH-RG
213 FA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNII
214 IWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFVGTIFLFSF
215 VVPTLMILYYYSQIVGHVFNH---------------------------------------
216 ------------------------------------------------------------
217 --------------------EKALREQAKKMNVESLRSNVDKSKETA-------------
218 ----------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSL---LTPGA
219 TMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPW-LGVNEKSGEA----SSAQSTTTQ
220 EQT---------------------------------------------------------
221 ------------------------------------QQTSA-A---
222 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
223 MT-----------NATGPQMAYYGAASMDFGYPE------------------------GV
224 SIVDFVRP----------------------EIKP--YVHQHWYNYPPVNPMWHYLLGVIY
225 LFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGV
226 WM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVVFALI
227 SWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNTFSYNIFIFVFDY
228 FLPAAIIVFSYVFIVKAIFAH---------------------------------------
229 ------------------------------------------------------------
230 --------------------EAAMRAQAKKMNVSTLRS-NEADAQRA-------------
231 ----------------EIRIAKTALVNVSLWFICWTPYALISLKGVMGDTSG---ITPLV
232 STLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPW-FCVHETETKS-NDDSQSNSTVAQ
233 ------------------------------------------------------------
234 ---------------------------------------DK-A---
235 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
236 MA-----------NVTGPQMAFYGSGAATFGYPE------------------------GM
237 TVADFVPD----------------------RVKH--MVLDHWYNYPPVNPMWHYLLGVVY
238 LFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGR
239 WM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATFMCGL
240 AWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNTITYNICIFIFDF
241 FLPASVIVFSYVFIVKAIFAH---------------------------------------
242 ------------------------------------------------------------
243 --------------------EAAMRAQAKKMNVTNLRS-NEAETQRA-------------
244 ----------------EIRIAKTALVNVSLWFICWTPYAAITIQGLLGNAEG---ITPLL
245 TTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPW-FCVHEKDPND-VEENQSSNTQTQ
246 ------------------------------------------------------------
247 ---------------------------------------EK-S---
248 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
249 ME-----SFAVAAAQLGPHFA-----PLS-----------------------------NG
250 SVVDKVTP----------------------DMAH--LISPYWNQFPAMDPIWAKILTAYM
251 IMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ET
252 WV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKM--
253 -------------------------YVPEGNLTSCGIDYLE--RDWNPRSYLIFYSIFVY
254 YIPLFLICYSYWFIIAAVSAH---------------------------------------
255 ------------------------------------------------------------
256 --------------------EKAMREQAKKMNVKSLRS-SEDAEKSA-------------
257 ----------------EGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-EG---LTPLN
258 TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSDAQSQATASE
259 AE----------------------------------------------------------
260 ---------------------------------------SK-A---
261 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
262 ME-----SFAVAAAQLGPHFA-----PLS-----------------------------NG
263 SVVDKVTP----------------------DMAH--LISPYWNQFPAMDPIWAKILTAYM
264 IMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ET
265 WV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAY
266 IWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYLIFYSIFVY
267 YIPLFLICYSYWFIIAAVSAH---------------------------------------
268 ------------------------------------------------------------
269 --------------------EKAMREQAKKMNVKSLRS-SEDAEKSA-------------
270 ----------------EGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-EG---LTPLN
271 TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSDAQSQATASE
272 AE----------------------------------------------------------
273 ---------------------------------------SK-A---
274 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
275 MD-----SFAAVATQLGPQFA-----APS-----------------------------NG
276 SVVDKVTP----------------------DMAH--LISPYWDQFPAMDPIWAKILTAYM
277 IIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ET
278 WV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAY
279 IWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYLIFYSIFVY
280 YIPLFLICYSYWFIIAAVSAH---------------------------------------
281 ------------------------------------------------------------
282 --------------------EKAMREQAKKMNVKSLRS-SEDADKSA-------------
283 ----------------EGKLAKVALVTISLWFMAWTPYLVINCMGLFKF-EG---LTPLN
284 TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSEAQSQATTSE
285 AE----------------------------------------------------------
286 ---------------------------------------SK-A---
287 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
288 MERSHLPETPFDLAHSGPRFQ-----AQSSG---------------------------NG
289 SVLDNVLP----------------------DMAH--LVNPYWSRFAPMDPMMSKILGLFT
290 LAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ET
291 WV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKILF
292 IWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNPRSYLITYSLFVY
293 YTPLFLICYSYWFIIAAVAAH---------------------------------------
294 ------------------------------------------------------------
295 --------------------EKAMREQAKKMNVKSLRS-SEDCDKSA-------------
296 ----------------EGKLAKVALTTISLWFMAWTPYLVICYFGLFKI-DG---LTPLT
297 TIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPM-CVFGNTDEPKPDAPASDTETTSE
298 AD----------------------------------------------------------
299 ---------------------------------------SK-A---
300 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
301 MERSLLPEPPLAMALLGPRFE-----AQTGG---------------------------NR
302 SVLDNVLP----------------------DMAP--LVNPHWSRFAPMDPTMSKILGLFT
303 LVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ET
304 WV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKIAF
305 IWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNPRSYLITYSLFVY
306 YTPLFMICYSYWFIIATVAAH---------------------------------------
307 ------------------------------------------------------------
308 --------------------EKAMRDQAKKMNVKSLRS-SEDCDKSA-------------
309 ----------------ENKLAKVALTTISLWFMAWTPYLIICYFGLFKI-DG---LTPLT
310 TIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPM-CVCGTTDEPKPDAPPSDTETTSE
311 AE----------------------------------------------------------
312 ---------------------------------------SK-D---
313 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
314 MI-----------AVSGPSYE-----AFSYGGQARFN---------------------NQ
315 TVVDKVPP----------------------DMLH--LIDANWYQYPPLNPMWHGILGFVI
316 GMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ET
317 WV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALIRIIA
318 IWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLSASYLVCYGIWVY
319 FVPLFLIIYSYWFIIQAVAAH---------------------------------------
320 ------------------------------------------------------------
321 --------------------EKNMREQAKKMNVASLRS-SENQNTSA-------------
322 ----------------ECKLAKVALMTISLWFMAWTPYLVINFSGIFNL-VK---ISPLF
323 TIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPS-LAC-AAEPSS-DAVSTTSGTTTV
324 TDN---------------------------------------------------------
325 ------------------------------------EK-SN-A---
326 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
327 M-------------ANQLSYS-----SLGWPYQP------------------------NA
328 SVVDTMPK----------------------EMLY--MIHEHWYAFPPMNPLWYSILGVAM
329 IILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ET
330 WI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKATLLLLF
331 VWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSSASYVVIYGLAVY
332 FLPLITMIYCYFFIVHAVAEH---------------------------------------
333 ------------------------------------------------------------
334 --------------------EKQLREQAKKMNVASLRANADQQKQSA-------------
335 ----------------ECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSGTR---LTPLA
336 TIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPS-LACGSGESGS-DVKSEASATTTM
337 EEK---------------------------------------------------------
338 ------------------------------------PKIPE-A---
339 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
340 MVE-----------------------STTLVNQTWWY---------------------NP
341 TVD----------------------------------IHPHWAKFDPIPDAVYYSVGIFI
342 GVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KK
343 WI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIF
344 VWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPSTRSFILCMYFCGF
345 MLPIIIIAFCYFNIVMSVSNH---------------------------------------
346 ------------------------------------------------------------
347 --------------------EKEMAAMAKRLNAKELR--KAQAGASA-------------
348 ----------------EMKLAKISMVIITQFMLSWSPYAIIALLAQFGPAEW---VTPYA
349 AELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECEDANDAEEEVVA
350 SER--GGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQGAYPPPQGY
351 PPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQ-A---
352 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
353 MGR-----------------------DLR-DNETWWY---------------------NP
354 SIV----------------------------------VHPHWREFDQVPDAVYYSLGIFI
355 GICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KK
356 WI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIF
357 VWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTTRSNILCMFILGF
358 FGPILIIFFCYFNIVMSVSNH---------------------------------------
359 ------------------------------------------------------------
360 --------------------EKEMAAMAKRLNAKELR--KAQAGANA-------------
361 ----------------EMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEW---VTPYA
362 AQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIPA
363 GESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQGY--PPQGY
364 PPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQ-A---
365 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
366 MMDVNSSGRPDLYGHLRSFL-----LPEVGRGLPDLSPDGGADPVAGSWAPHLLS---EV
367 TASPAPTW------------DAPPDNASGCGEQIN------------YGRVEKVVIGSIL
368 TLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGK
369 WI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILS
370 VWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAF
371 YIPMSVMLFMYYQIYKAAR-----------------------------------------
372 ---------KSAAKHKFPGFPRVEPDSVIAL-----------------------------
373 --------------------NGIVKLQKEVEECANLSRLL--------------------
374 ----KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
375 ERTFLWLGYANSLINPFIYAFFNRDLRTTYRSL----L---QCQYRNINRKLSAAGMHEA
376 LKLAERPERPEFVLQNADYCRKK-------------------------------------
377 ------------------------------------------GHDS
378 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
379 M-------------------------------------------------PHLLSGFLEV
380 TASPAPTW------------DAPPDNVSGCGEQIN------------YGRVEKVVIGSIL
381 TLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGK
382 WI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILS
383 VWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAF
384 YIPMSVMLFMYYQIYKAAR-----------------------------------------
385 ---------KSAAKHKFPGFPRVQPESVISL-----------------------------
386 --------------------NGVVKLQKEVEECANLSRLL--------------------
387 ----KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
388 ERTCLWLGYANSLINPFIYAFFNRDLRPTSRSL----L---QCQYRNINRKLSAAGMHEA
389 LKLAERPERSEFVLQNSDHCGKK-------------------------------------
390 ------------------------------------------GHDT
391 > 31=p A47425 serotonin receptor 5HT-7 - rat
392 M-------------------------------------------------PHLLSGFLEV
393 TASPAPTW------------DAPPDNVSGCGEQIN------------YGRVEKVVIGSIL
394 TLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGK
395 WI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILS
396 VWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAF
397 YIPMSVMLFMYYQIYKAAR-----------------------------------------
398 ---------KSAAKHKFPGFPRVQPESVISL-----------------------------
399 --------------------NGVVKLQKEVEECANLSRLL--------------------
400 ----KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
401 ERTCLWLGYANSLINPFIYAFFNRDLRTTYRSL----L---QCQYRNINRKLSAAGMHEA
402 LKLAERPERSEFVLQNSDHCGKK-------------------------------------
403 ------------------------------------------GHDT
404 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
405 MDVLSPGQ-----------------GNNTTSPPAPFETGG------------------NT
406 TGISDVTV------------------------------------------SYQVITSLLL
407 GTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NK
408 WT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISL
409 TWLIGFLI-SIPPMLG-WRTPEDRSDPDA---CTISKDH----------GYTIYSTFGAF
410 YIPLLLMLVLYGRIFRAARFRIRK------------------------------------
411 ---TVKKVEKTGADTRHGASPAPQPKKS-----------VNGESGSR---------NWRL
412 GVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAG--PTPCAPASFER
413 KNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPTLL
414 GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKI----I-----KCKFCRQ----------
415 ------------------------------------------------------------
416 ----------------------------------------------
417 > 33=p A35181 serotonin receptor class 1A - rat
418 MDVFSFGQ-----------------GNNTTASQEPFGTGG------------------NV
419 TSISDVTF------------------------------------------SYQVITSLLL
420 GTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NK
421 WT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISL
422 TWLIGFLI-SIPPMLG-WRTPEDRSDPDA---CTISKDH----------GYTIYSTFGAF
423 YIPLLLMLVLYGRIFRAARFRIRK------------------------------------
424 ---TVRKVEKKGAGTSLGTSSAPPPKKS-----------LNGQPGSG---------DWRR
425 CAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESG--SNSYAPACLER
426 KNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPALL
427 GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKI----I-----KCKFCRR----------
428 ------------------------------------------------------------
429 ----------------------------------------------
430 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
431 MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTG------------------LV
432 TSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLVLTSVIL
433 GLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KV
434 WF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMV
435 VWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAF
436 YLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNS
437 PDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS----------SERL
438 KQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS-------------
439 RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDPE-G-IPPFA
440 RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKI----LFG---KYRRGHR----------
441 ------------------------------------------------------------
442 ----------------------------------------------
443 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
444 MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTG------------------LV
445 TSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLVLTSVIL
446 GLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KV
447 WF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMV
448 VWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAF
449 YLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNS
450 PDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS----------SERL
451 KQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS-------------
452 RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDPE-G-IPPFA
453 RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKI----LFG---KYRRGHR----------
454 ------------------------------------------------------------
455 ----------------------------------------------
456 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
457 MEGAE-GQEELDWEAL--YLRLP--LQNCSWNSTGWEPNW------------------NV
458 TVVPNTTW---------WQASAPFDTPAALVRAAAK--------------------AVVL
459 GLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QR
460 WT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIAC
461 VWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSF
462 YVPVLIILILYWRIYQTARKRIR-------------------------------------
463 --------RRRGATARGGVGPPP---------VPAGGALVAGGGSGGIAAAVVAVIGRPL
464 PTISETTTTGFTNVSS----NNTS---PEKQSCANGLEADPPTTGYGAVAAAYYPSLVRR
465 KPKEAADSK------RERKAAKTLAIITGAFVACWLPFFVLAILVPT-CDCE---VSPVL
466 TSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRL----LCGRRVRRRRAPQ----------
467 ------------------------------------------------------------
468 ----------------------------------------------
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