1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 M-------------------NGTEGDNFYVPFS---------------------------
3 ----------NKTGLARSPY----------------------EYPQY-YLAEPWK-----
4 ----YSA----LAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVL
5 FG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMG
6 N-FRFGNTHAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNP
7 NFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTV--------------------------
8 ------------------------------------------------------------
9 ---------------------------KEAAAAQQ----------ESASTQKA-------
10 --------------------EKEVTRMVVLMVIGFLVCWVPYASVAFYIFT---HQGSD-
11 FGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITT----LCCGKNPLGDDE--SGAS
12 TSKTEVSS----------------------------------------------------
13 --------------------------------------VSTSPVSPA
14 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
15 M-------------------NGTEGPNFYVPFS---------------------------
16 ----------NITGVVRSPF----------------------EQPQY-YLAEPWQ-----
17 ----FSM----LAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVF
18 GG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMS
19 N-FRFGENHAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKP
20 EVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTV--------------------------
21 ------------------------------------------------------------
22 ---------------------------KEAAAQQQ----------ESATTQKA-------
23 --------------------EKEVTRMVIIMVIFFLICWLPYASVAMYIFT---HQGSN-
24 FGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTS----LCCGKNPLGDDE--ASAT
25 ASKTETSQ----------------------------------------------------
26 -------------------------------------------VAPA
27 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
28 M-------------------NGTEGINFYVPMS---------------------------
29 ----------NKTGVVRSPF----------------------EYPQY-YLAEPWK-----
30 ----YRL----VCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMAC
31 FG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMG
32 N-FRFSATHAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNP
33 DYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKV--------------------------
34 ------------------------------------------------------------
35 ---------------------------REAAAQQQ----------ESATTQKA-------
36 --------------------EKEVTRMVILMVLGFMLAWTPYAVVAFWIFT---NKGAD-
37 FTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITT----ICCGKNPFGDEDVSSTVS
38 QSKTEVSS----------------------------------------------------
39 --------------------------------------VSSSQVSPA
40 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
41 M-------------------NGTEGKNFYVPMS---------------------------
42 ----------NRTGLVRSPF----------------------EYPQY-YLAEPWQ-----
43 ----FKI----LALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVC
44 FG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMG
45 S-FKFSSSHAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNP
46 DYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTV--------------------------
47 ------------------------------------------------------------
48 ---------------------------KAAAAQQQ----------DSASTQKA-------
49 --------------------EREVTKMVILMVFGFLIAWTPYATVAAWIFF---NKGAD-
50 FSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTT----IFCGKNPLGDDE-SSTVS
51 TSKTEVSS----------------------------------------------------
52 -------------------------------------------VSPA
53 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
54 M-------------------NGTEGNNFYVPLS---------------------------
55 ----------NRTGLVRSPF----------------------EYPQY-YLAEPWQ-----
56 ----FKL----LAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVC
57 FG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMG
58 S-FKFSSTHASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNP
59 EYNNESYVLYMFICHFILPVTIIFFTYGRLVCTV--------------------------
60 ------------------------------------------------------------
61 ---------------------------KAAAAQQQ----------DSASTQKA-------
62 --------------------EREVTKMVILMVLGFLVAWTPYATVAAWIFF---NKGAA-
63 FSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTT----LFCGKNPLGDEE-SSTVS
64 TSKTEVSS----------------------------------------------------
65 -------------------------------------------VSPA
66 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
67 M-----------------KQVPEFHEDFYIPIPLD-------------------------
68 ----------INNLSAYSPF----------------------LVPQD-HLGNQGI-----
69 ----FMA----MSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAI
70 FG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLG
71 N-FTFKTPHAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNN
72 KYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITL--------------------------
73 ------------------------------------------------------------
74 ---------------------------KLAAKAQA----------DSASTQKA-------
75 --------------------EREVTKMVVVMVLGFLVCWAPYASFSLWIVS---HRGEE-
76 FDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMMK-----MVCGKNIEEDEASTSSQV
77 TQVSSVAP----------------------------------------------------
78 ---------------------------------------------EK
79 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
80 M-------------------RKMSEEEFYL------------------------------
81 ----------FKNISSVGPW----------------------DGPQY-HIAPVWA-----
82 ----FYL----QAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCI
83 FSVFPVFVASCN--GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFG
84 N-FRFSSKHALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGT
85 KYRSESYTWFLFIFCFIVPLSLICFSYTQLLRAL--------------------------
86 ------------------------------------------------------------
87 ---------------------------KAVAAQQQ----------ESATTQKA-------
88 --------------------EREVSRMVVVMVGSFCVCYVPYAAFAMYMVN---NRNHG-
89 LDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMK-----MVCGKAMTDESDTCSSQK
90 TEVSTVSS----------------------------------------------------
91 -----------------------------------------TQVGPN
92 > 8=opsin, greensensitive human (fragment) S07060
93 ------------------------------------------------------------
94 ------------------------------------------------------------
95 ------------------------------------------------------DLAETV
96 IA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFG
97 N-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSS
98 YPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAI--------------------------
99 ------------------------------------------------------------
100 ---------------------------RAVAKQQK----------ESESTQKA-------
101 --------------------EKEVTRMVVVMVLAFC------------------------
102 ------------------------------------------------------------
103 ------------------------------------------------------------
104 -----------------------------------------------
105 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
106 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTY------------------------------
107 ----------TNSNSTRGPF----------------------EGPNY-HIAPRWV-----
108 ----YHL----TSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETV
109 IA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFG
110 N-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSS
111 YPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAI--------------------------
112 ------------------------------------------------------------
113 ---------------------------RAVAKQQK----------ESESTQKA-------
114 --------------------EKEVTRMVVVMVLAFCFCWGPYAFFACFAAA---NPGYP-
115 FHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQL------FGKKVDDGSELSSASK
116 TEVSSV------------------------------------------------------
117 -----------------------------------------SSVSPA
118 > 10== Z68193 1 human Red Opsin <>[]
119 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTY------------------------------
120 ----------TNSNSTRGPF----------------------EGPNY-HIAPRWV-----
121 ----YHL----TSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETV
122 IA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFG
123 N-VRFDAKLAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSS
124 YPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAI--------------------------
125 ------------------------------------------------------------
126 ---------------------------RAVAKQQK----------ESESTQKA-------
127 --------------------EKEVTRMVVVMIFAYCVCWGPYTFFACFAAA---NPGYA-
128 FHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQL------FGKKVDDGSELSSASK
129 TEVSSV------------------------------------------------------
130 -----------------------------------------SSVSPA
131 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
132 MTEAWNVAVFAARRSRDD-DDTTRGSVFTY------------------------------
133 ----------TNTNNTRGPF----------------------EGPNY-HIAPRWV-----
134 ----YNL----VSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETL
135 VA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFG
136 N-IKFDSKLAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSV
137 ELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAI--------------------------
138 ------------------------------------------------------------
139 ---------------------------RAVAAQQK----------ESESTQKA-------
140 --------------------EREVSRMVVVMIVAFCICWGPYASFVSFAAA---NPGYA-
141 FHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQL------FGKKVDDGSEASTTSR
142 TEVSSVSN----------------------------------------------------
143 -----------------------------------------SSVAPA
144 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
145 MA-AWEAAFAARRRHEE--EDTTRDSVFTY------------------------------
146 ----------TNSNNTRGPF----------------------EGPNY-HIAPRWV-----
147 ----YNL----TSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETV
148 IA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFG
149 N-IKFDGKLAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSS
150 DPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAI--------------------------
151 ------------------------------------------------------------
152 ---------------------------RAVAAQQK----------ESESTQKA-------
153 --------------------EKEVSRMVVVMIVAYCFCWGPYTFFACFAAA---NPGYA-
154 FHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQL------FGKKVDDGSEVST-SR
155 TEVSSVSN----------------------------------------------------
156 -----------------------------------------SSVSPA
157 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
158 M-------------------SSNSSQ----------------------------------
159 ----------APPNGTPGPF----------------------DGPQWPYQAPQST-----
160 ----YVG----VAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTL
161 CG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLG
162 D-FQFQRRHAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGS
163 --NNNSYILSLFVTCFVLPLSLILFSYTNLLLTL--------------------------
164 ------------------------------------------------------------
165 ---------------------------RAAAAQQK----------EADTTQRA-------
166 --------------------EREVTRMVIVMVMAFLLCWLPYSTFALVVAT---HKGII-
167 IQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEM----LCCGYQPQRTGKASPGTP
168 GPHADVTA----------------------------------------------------
169 ----------------------------------AGLRNKVMPAHPV
170 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
171 M-------------------ESGNVSSSLFGNVSTALRPEA----R-----------LSA
172 ---E------TRLLGWNVPP----------------------EELR--HIPEHWLTYPEP
173 PESMNYL----LGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMV
174 K--TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPME
175 G--KMTHGKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--D
176 NFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSH-----------------------
177 ------------------------------------------------------------
178 --------------------------EKALRDQAKKMNVESLRSNVDKNKETA-------
179 --------------------EIRIAKAAITICFLFFCSWTPYGVMSLIGAF---GDKTL-
180 LTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPW-LALNEKAPES----SAVA
181 STSTTQEP----------------------------------------------------
182 -----------------------------------------QQTTAA
183 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
184 M-------------------EYHNVS-SVLGNVSSVLRPDA----R-----------LSA
185 ---E------SRLLGWNVPP----------------------DELR--HIPEHWLIYPEP
186 PESMNYL----LGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMI
187 K--TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPME
188 G--KMTHGKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--D
189 NFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSH-----------------------
190 ------------------------------------------------------------
191 --------------------------EKALRDQAKKMNVDSLRSNVDKSKEAA-------
192 --------------------EIRIAKAAITICFLFFASWTPYGVMSLIGAF---GDKTL-
193 LTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPW-LAISEKAPES----RAAI
194 STSTTQEQ----------------------------------------------------
195 -----------------------------------------QQTTAA
196 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
197 M-------------------E------PLCNASEPPLRPEA----R------------SS
198 GNGD------LQFLGWNVPP----------------------DQIQ--YIPEHWLTQLEP
199 PASMHYM----LGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCL
200 K--APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMN
201 R--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--D
202 NFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSH-----------------------
203 ------------------------------------------------------------
204 --------------------------EKALREQAKKMNVESLRSNVDKSKETA-------
205 --------------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAF---GDKSL-
206 LTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPW-LGVNEKSGEI----SSAQ
207 STTTQEQ-----------------------------------------------------
208 -----------------------------------------QQTTAA
209 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
210 M-------------------D------ALCNASEPPLRPEA----R-----------MSS
211 GSDE------LQFLGWNVPP----------------------DQIQ--YIPEHWLTQLEP
212 PASMHYM----LGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCL
213 K--APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMN
214 R--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--D
215 NFDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNH-----------------------
216 ------------------------------------------------------------
217 --------------------------EKALREQAKKMNVESLRSNVDKSKETA-------
218 --------------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAF---GDKSL-
219 LTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPW-LGVNEKSGEA----SSAQ
220 STTTQEQT----------------------------------------------------
221 -----------------------------------------QQTSAA
222 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
223 M-------------------T-----------NATGPQMAYYGAAS-----------MDF
224 GYPE------GVSIVDFVRP----------------------EIKP--YVHQHWYNYPPV
225 NPMWHYL----LGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLT
226 TN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFN
227 G-PKLTTGKAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--Q
228 DFNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAH-----------------------
229 ------------------------------------------------------------
230 --------------------------EAAMRAQAKKMNVSTLRS-NEADAQRA-------
231 --------------------EIRIAKTALVNVSLWFICWTPYALISLKGVM---GDTSG-
232 ITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPW-FCVHETETKSNDDSQSNS
233 TVAQDKA-----------------------------------------------------
234 -----------------------------------------------
235 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
236 M-------------------A-----------NVTGPQMAFYGSGA-----------ATF
237 GYPE------GMTVADFVPD----------------------RVKH--MVLDHWYNYPPV
238 NPMWHYL----LGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLT
239 TN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFN
240 G-PKLTQGKATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--R
241 DMNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAH-----------------------
242 ------------------------------------------------------------
243 --------------------------EAAMRAQAKKMNVTNLRS-NEAETQRA-------
244 --------------------EIRIAKTALVNVSLWFICWTPYAAITIQGLL---GNAEG-
245 ITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPW-FCVHEKDPNDVEENQSSN
246 TQTQEKS-----------------------------------------------------
247 -----------------------------------------------
248 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
249 M-------------------E-----SFAVAAAQLGPHFA-----P-----------LS-
250 ----------NGSVVDKVTP----------------------DMAH--LISPYWNQFPAM
251 DPIWAKI----LTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMI
252 TN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMA
253 G-RPMTIPLALGKM---------------------------YVPEGNLTSCGIDYLE--R
254 DWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAH-----------------------
255 ------------------------------------------------------------
256 --------------------------EKAMREQAKKMNVKSLRS-SEDAEKSA-------
257 --------------------EGKLAKVALVTITLWFMAWTPYLVINCMGLF---KF-EG-
258 LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSDAQSQ
259 ATASEAE-----------------------------------------------------
260 --------------------------------------------SKA
261 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
262 M-------------------E-----SFAVAAAQLGPHFA-----P-----------LS-
263 ----------NGSVVDKVTP----------------------DMAH--LISPYWNQFPAM
264 DPIWAKI----LTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMI
265 TN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMA
266 G-RPMTIPLALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--R
267 DWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAH-----------------------
268 ------------------------------------------------------------
269 --------------------------EKAMREQAKKMNVKSLRS-SEDAEKSA-------
270 --------------------EGKLAKVALVTITLWFMAWTPYLVINCMGLF---KF-EG-
271 LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSDAQSQ
272 ATASEAE-----------------------------------------------------
273 --------------------------------------------SKA
274 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
275 M-------------------D-----SFAAVATQLGPQFA-----A-----------PS-
276 ----------NGSVVDKVTP----------------------DMAH--LISPYWDQFPAM
277 DPIWAKI----LTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMI
278 TN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMA
279 G-RPMTIPLALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--R
280 DWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAH-----------------------
281 ------------------------------------------------------------
282 --------------------------EKAMREQAKKMNVKSLRS-SEDADKSA-------
283 --------------------EGKLAKVALVTISLWFMAWTPYLVINCMGLF---KF-EG-
284 LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSEAQSQ
285 ATTSEAE-----------------------------------------------------
286 --------------------------------------------SKA
287 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
288 M-------------------ERSHLPETPFDLAHSGPRFQ-----A-----------QSS
289 G---------NGSVLDNVLP----------------------DMAH--LVNPYWSRFAPM
290 DPMMSKI----LGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMA
291 SQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGIN
292 G-TPMTIKTSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--R
293 MWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAH-----------------------
294 ------------------------------------------------------------
295 --------------------------EKAMREQAKKMNVKSLRS-SEDCDKSA-------
296 --------------------EGKLAKVALTTISLWFMAWTPYLVICYFGLF---KI-DG-
297 LTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPM-CVFGNTDEPKPDAPASDT
298 ETTSEAD-----------------------------------------------------
299 --------------------------------------------SKA
300 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
301 M-------------------ERSLLPEPPLAMALLGPRFE-----A-----------QTG
302 G---------NRSVLDNVLP----------------------DMAP--LVNPHWSRFAPM
303 DPTMSKI----LGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMA
304 SQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGIN
305 G-TPMTIKTSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--R
306 QWNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAH-----------------------
307 ------------------------------------------------------------
308 --------------------------EKAMRDQAKKMNVKSLRS-SEDCDKSA-------
309 --------------------ENKLAKVALTTISLWFMAWTPYLIICYFGLF---KI-DG-
310 LTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPM-CVCGTTDEPKPDAPPSDT
311 ETTSEAE-----------------------------------------------------
312 --------------------------------------------SKD
313 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
314 M-------------------I-----------AVSGPSYE-----A-----------FSY
315 GGQARFN---NQTVVDKVPP----------------------DMLH--LIDANWYQYPPL
316 NPMWHGI----LGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMF
317 CM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLS
318 G-KPLSINGALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--R
319 GLLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAH-----------------------
320 ------------------------------------------------------------
321 --------------------------EKNMREQAKKMNVASLRS-SENQNTSA-------
322 --------------------ECKLAKVALMTISLWFMAWTPYLVINFSGIF---NLVK--
323 ISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPS-LACAAEPSSDAVSTTSGT
324 TTVTDNEK----------------------------------------------------
325 --------------------------------------------SNA
326 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
327 M--------------------------------ANQLSYS-----S-----------LGW
328 PYQP------NASVVDTMPK----------------------EMLY--MIHEHWYAFPPM
329 NPLWYSI----LGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMA
330 FM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMA
331 A-APLTHKKATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--K
332 DWSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEH-----------------------
333 ------------------------------------------------------------
334 --------------------------EKQLREQAKKMNVASLRANADQQKQSA-------
335 --------------------ECRLAKVAMMTVGLWFMAWTPYLIISWAGVF---SSGTR-
336 LTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPS-LACGSGESGS-DVKSEAS
337 ATTTMEEK----------------------------------------------------
338 -----------------------------------------PKIPEA
339 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
340 M-------------------VE-----------------------S-----------TTL
341 VNQTWWY---NPTVD----------------------------------IHPHWAKFDPI
342 PDAVYYS----VGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSA
343 INGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMA
344 ASKKMSHRRAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--T
345 DPSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNH-----------------------
346 ------------------------------------------------------------
347 --------------------------EKEMAAMAKRLNAKELR--KAQAGASA-------
348 --------------------EMKLAKISMVIITQFMLSWSPYAIIALLAQF---GPAEW-
349 VTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECEDANDAE
350 EEVVASER--GGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQGAYP
351 PPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
352 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
353 M-------------------GR-----------------------D-----------LR-
354 DNETWWY---NPSIV----------------------------------VHPHWREFDQV
355 PDAVYYS----LGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSL
356 VNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMA
357 ASKKMSHRRAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--R
358 DSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNH-----------------------
359 ------------------------------------------------------------
360 --------------------------EKEMAAMAKRLNAKELR--KAQAGANA-------
361 --------------------EMRLAKISIVIVSQFLLSWSPYAVVALLAQF---GPLEW-
362 VTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAE
363 TEIPAGESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQGY--
364 PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
365 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
366 MM-----------------DVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGS
367 WAPHLLS---EVTASPAPTW----------------------------DAPPDNASGCGE
368 QINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAV
369 AV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLT
370 YPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF-----
371 -----GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIAL---
372 ------------------------------------------------------------
373 --------------------------NGIVKLQKEVEECANLSRLLKHERKNI-------
374 ---------------SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-
375 IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSL----LQCQYRNINRKLSAAGMH
376 EALKLAERPERPEFVLQNADYCRKKGHDS-------------------------------
377 -----------------------------------------------
378 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
379 M-----------------------------------------------------------
380 --PHLLSGFLEVTASPAPTW----------------------------DAPPDNVSGCGE
381 QINYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAV
382 AV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLT
383 YPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF-----
384 -----GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISL---
385 ------------------------------------------------------------
386 --------------------------NGVVKLQKEVEECANLSRLLKHERKNI-------
387 ---------------SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-
388 IPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSL----LQCQYRNINRKLSAAGMH
389 EALKLAERPERSEFVLQNSDHCGKKGHDT-------------------------------
390 -----------------------------------------------
391 > 31=p A47425 serotonin receptor 5HT-7 - rat
392 M-----------------------------------------------------------
393 --PHLLSGFLEVTASPAPTW----------------------------DAPPDNVSGCGE
394 QINYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAV
395 AV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLT
396 YPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF-----
397 -----GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISL---
398 ------------------------------------------------------------
399 --------------------------NGVVKLQKEVEECANLSRLLKHERKNI-------
400 ---------------SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-
401 IPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSL----LQCQYRNINRKLSAAGMH
402 EALKLAERPERSEFVLQNSDHCGKKGHDT-------------------------------
403 -----------------------------------------------
404 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
405 M-------------------DVLSPGQG--------------------------------
406 ----------NNTTSPPAPF----------------------------ETGGNTTGISDV
407 TVSYQVI----TSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSV
408 LV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPID
409 YVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH-----
410 -----GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK--------------------
411 -------------------TVKKVEKTGADTRHGASPAPQPKKSV----------NGESG
412 SRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPA
413 SFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF---CESSCH
414 MPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKI----IKCKFCRQ----------
415 ------------------------------------------------------------
416 -----------------------------------------------
417 > 33=p A35181 serotonin receptor class 1A - rat
418 M-------------------DVFSFGQG--------------------------------
419 ----------NNTTASQEPF----------------------------GTGGNVTSISDV
420 TFSYQVI----TSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSV
421 LV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPID
422 YVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH-----
423 -----GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK--------------------
424 -------------------TVRKVEKKGAGTSLGTSSAPPPKKSL----------NGQPG
425 SGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYAPA
426 CLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF---CESSCH
427 MPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKI----IKCKFCRR----------
428 ------------------------------------------------------------
429 -----------------------------------------------
430 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
431 M-------------------ANFTFGDLALDVARMGGLASTPSGLR-----------STG
432 LTTPGLSPTGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVY
433 SHEHLVL----TSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAV
434 LV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-ID
435 YIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK-----
436 -----GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVAS
437 PKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNS
438 SSSERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS-------
439 ------RT----REKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF---VDPEG-
440 IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKI----LFGKYRRGHR--------
441 ------------------------------------------------------------
442 -----------------------------------------------
443 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
444 M-------------------ANFTFGDLALDVARMGGLASTPSGLR-----------STG
445 LTTPGLSPTGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVY
446 SHEHLVL----TSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAV
447 LV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-ID
448 YIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK-----
449 -----GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVAS
450 PKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNS
451 SSSERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS-------
452 ------RT----REKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF---VDPEG-
453 IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKI----LFGKYRRGHR--------
454 ------------------------------------------------------------
455 -----------------------------------------------
456 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
457 M-------------------EGAEGQEELDWEALYLRLPLQNCSWN-----------STG
458 WEPNW-----NVTVVPNTTW---------------------------------WQASAPF
459 DTPAALVRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVAC
460 LV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-ID
461 YIHASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV-----
462 -----GYQIFATASSFYVPVLIILILYWRIYQTARKRIRR--------------------
463 -------------------------RRGATARGGVGPPPVPAGGALVA------GGGSGG
464 IAAAVVAVIGRPLPTISETTTTGFTNVSSNNTSPEKQSCANGLEADPPTTGYGAVAAAYY
465 PSLVRRKP----KEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPT---CDCE--
466 VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRL----LCGRRVRRRRAPQ-----
467 ------------------------------------------------------------
468 -----------------------------------------------
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