1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 --------------------MN-------------------------GTE-------GDN
3 FYVP-----------------------------------------FSNKTG---------
4 --LARSPYEYPQY-YLAEPW----------------------KYSALAAYMFFLILVGFP
5 VNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYFV--FGPTM
6 CSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNTHAIMGVAFTWIMALAC-
7 AAPPLVG-WS-----RYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVIIFF
8 CYGRLLCTVKEAAAAQQESA----------------------------------------
9 ------------------------------------------------------------
10 -----------------------------------------STQKAEKEVTRMVVLMVIG
11 FLVCWVPYASVAFYIFT-HQGS-D-FGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCM
12 ITTL-----CCGKNPLGDDE-SG-ASTSKTEVSSVST-----------------------
13 ------------------------------------------------------------
14 ------------SPV-------SP-A
15 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
16 --------------------MN-------------------------GTE-------GPN
17 FYVP-----------------------------------------FSNITG---------
18 --VVRSPFEQPQY-YLAEPW----------------------QFSMLAAYMFLLIVLGFP
19 INFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYFV--FGPTG
20 CNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGENHAIMGVAFTWVMALAC-
21 AAPPLVG-WS-----RYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFF
22 CYGQLVFTVKEAAAQQQESA----------------------------------------
23 ------------------------------------------------------------
24 -----------------------------------------TTQKAEKEVTRMVIIMVIF
25 FLICWLPYASVAMYIFT-HQGS-N-FGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCM
26 LTSL-----CCGKNPLGDDE-AS-ATASKTE-----T-----------------------
27 ------------------------------------------------------------
28 ------------SQV-------AP-A
29 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
30 --------------------MN-------------------------GTE-------GIN
31 FYVP-----------------------------------------MSNKTG---------
32 --VVRSPFEYPQY-YLAEPW----------------------KYRLVCCYIFFLISTGLP
33 INLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYFV--FGPVG
34 CAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSATHAMMGIAFTWVMAFSC-
35 AAPPLFG-WS-----RYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVVIFF
36 SYGRLICKVREAAAQQQESA----------------------------------------
37 ------------------------------------------------------------
38 -----------------------------------------TTQKAEKEVTRMVILMVLG
39 FMLAWTPYAVVAFWIFT-NKGA-D-FTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCM
40 ITTI-----CCGKNPFGDEDVSSTVSQSKTEVSSVSS-----------------------
41 ------------------------------------------------------------
42 ------------SQV-------SP-A
43 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
44 --------------------MN-------------------------GTE-------GKN
45 FYVP-----------------------------------------MSNRTG---------
46 --LVRSPFEYPQY-YLAEPW----------------------QFKILALYLFFLMSMGLP
47 INGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYFV--LGPTG
48 CAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSSHAFAGIAFTWVMALAC-
49 AAPPLFG-WS-----RYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVAVIFF
50 TYGRLVCTVKAAAAQQQDSA----------------------------------------
51 ------------------------------------------------------------
52 -----------------------------------------STQKAEREVTKMVILMVFG
53 FLIAWTPYATVAAWIFF-NKGA-D-FSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCM
54 LTTI-----FCGKNPLGDDE-SSTVSTSKTEVSS--------------------------
55 ------------------------------------------------------------
56 --------------V-------SP-A
57 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
58 --------------------MN-------------------------GTE-------GNN
59 FYVP-----------------------------------------LSNRTG---------
60 --LVRSPFEYPQY-YLAEPW----------------------QFKLLAVYMFFLICLGLP
61 INGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYFA--LGPTG
62 CAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSTHASAGIAFTWVMAMAC-
63 AAPPLVG-WS-----RYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVTIIFF
64 TYGRLVCTVKAAAAQQQDSA----------------------------------------
65 ------------------------------------------------------------
66 -----------------------------------------STQKAEREVTKMVILMVLG
67 FLVAWTPYATVAAWIFF-NKGA-A-FSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCM
68 LTTL-----FCGKNPLGDEE-SSTVSTSKTEVSS--------------------------
69 ------------------------------------------------------------
70 --------------V-------SP-A
71 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
72 --------------------MK-------------------------QVPE-----FHED
73 FYIP-----------------------------------------IPLDINN--------
74 -LSAYSPFLVPQD-HLGNQG----------------------IFMAMSVFMFFIFIGGAS
75 INILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYFI--FGATA
76 CKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTPHAIAGCILPWISALAA-
77 SLPPLFG-WS-----RYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTIVF
78 CYGQLLITLKLAAKAQADSA----------------------------------------
79 ------------------------------------------------------------
80 -----------------------------------------STQKAEREVTKMVVVMVLG
81 FLVCWAPYASFSLWIVS-HRGE-E-FDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCM
82 M-KM-----VCGKN-IEEDE-AS-TSSQVTQVSS--------------------------
83 ------------------------------------------------------------
84 --------------V-------APEK
85 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
86 --------------------MR-------------------------KMS-------EEE
87 FYL------------------------------------------FKNISS---------
88 --V--GPWDGPQY-HIAPVW----------------------AFYLQAAFMGTVFLIGFP
89 LNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYFV--FGRHV
90 CALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSKHALTVVLATWTIGIGV-
91 SIPPFFG-WS-----RFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICF
92 SYTQLLRALKAVAAQQQESA----------------------------------------
93 ------------------------------------------------------------
94 -----------------------------------------TTQKAEREVSRMVVVMVGS
95 FCVCYVPYAAFAMYMVN-NRNH-G-LDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACI
96 M-KM-----VCGKA-MTDES-DT-CSSQKTEVSTVSS-----------------------
97 ------------------------------------------------------------
98 ------------TQV-------GP-N
99 > 8=opsin, greensensitive human (fragment) S07060
100 ------------------------------------------------------------
101 ------------------------------------------------------------
102 ------------------------------------------------------------
103 -----------------------------DLAETVIA-STISIVNQVS-GYFV--LGHPM
104 CVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVW-
105 TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVL
106 CYLQVWLAIRAVAKQQKESE----------------------------------------
107 ------------------------------------------------------------
108 -----------------------------------------STQKAEKEVTRMVVVMVLA
109 FC----------------------------------------------------------
110 ------------------------------------------------------------
111 ------------------------------------------------------------
112 --------------------------
113 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
114 MAQQWS-LQRLAGRHPQDSYED-------------------------STQ-------SSI
115 FTYT-----------------------------------------NSNSTR---------
116 -----GPFEGPNY-HIAPRW----------------------VYHLTSVWMIFVVIASVF
117 TNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYFV--LGHPM
118 CVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVW-
119 TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVL
120 CYLQVWLAIRAVAKQQKESE----------------------------------------
121 ------------------------------------------------------------
122 -----------------------------------------STQKAEKEVTRMVVVMVLA
123 FCFCWGPYAFFACFAAA-NPGY-P-FHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCI
124 LQLF-------GKKVDDGSE-LS--SASKTEVSSV-------------------------
125 ------------------------------------------------------------
126 ------------SSV-------SP-A
127 > 10== Z68193 1 human Red Opsin <>[]
128 MAQQWS-LQRLAGRHPQDSYED-------------------------STQ-------SSI
129 FTYT-----------------------------------------NSNSTR---------
130 -----GPFEGPNY-HIAPRW----------------------VYHLTSVWMIFVVTASVF
131 TNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYFV--LGHPM
132 CVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWSAVW-
133 TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIML
134 CYLQVWLAIRAVAKQQKESE----------------------------------------
135 ------------------------------------------------------------
136 -----------------------------------------STQKAEKEVTRMVVVMIFA
137 YCVCWGPYTFFACFAAA-NPGY-A-FHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCI
138 LQLF-------GKKVDDGSE-LS--SASKTEVSSV-------------------------
139 ------------------------------------------------------------
140 ------------SSV-------SP-A
141 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
142 MTEAWNVAVFAARRSRDD--DD-------------------------TTR-------GSV
143 FTYT-----------------------------------------NTNNTR---------
144 -----GPFEGPNY-HIAPRW----------------------VYNLVSFFMIIVVIASCF
145 TNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYFI--LGHPL
146 CVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSKLAIIGIVFSWVWAWGW-
147 SAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFIIIV
148 CYLQVWMAIRAVAAQQKESE----------------------------------------
149 ------------------------------------------------------------
150 -----------------------------------------STQKAEREVSRMVVVMIVA
151 FCICWGPYASFVSFAAA-NPGY-A-FHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCI
152 MQLF-------GKKVDDGSE-AS--TTSRTEVSSVSN-----------------------
153 ------------------------------------------------------------
154 ------------SSV-------AP-A
155 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
156 MA-AWE-AAFAARRRHEE--ED-------------------------TTR-------DSV
157 FTYT-----------------------------------------NSNNTR---------
158 -----GPFEGPNY-HIAPRW----------------------VYNLTSVWMIFVVAASVF
159 TNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYFI--LGHPM
160 CVVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGKLAVAGILFSWLWSCAW-
161 TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAIIIL
162 CYLQVWLAIRAVAAQQKESE----------------------------------------
163 ------------------------------------------------------------
164 -----------------------------------------STQKAEKEVSRMVVVMIVA
165 YCFCWGPYTFFACFAAA-NPGY-A-FHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCI
166 LQLF-------GKKVDDGSE-VS--T-SRTEVSSVSN-----------------------
167 ------------------------------------------------------------
168 ------------SSV-------SP-A
169 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
170 -------------------------------------------------M-------SSN
171 SSQA-----------------------------------------PPNGTP---------
172 -----GPFDGPQWPYQAPQS----------------------TYVGVAVLMGTVVACASV
173 VNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFFV--FGRRM
174 CELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRRHAVSGCAFTWGWALLW-
175 SAPPLLG-WS-----SYVPEGLRTSCGPNWYTGGSN--NNSYILSLFVTCFVLPLSLILF
176 SYTNLLLTLRAAAAQQKEAD----------------------------------------
177 ------------------------------------------------------------
178 -----------------------------------------TTQRAEREVTRMVIVMVMA
179 FLLCWLPYSTFALVVAT-HKGI-I-IQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCL
180 LEML-----CCGYQPQRTGK-AS--PGTPGPHADVTA-----------------------
181 ------------------------------------------------------------
182 ------------AGLRNKVMPAHP-V
183 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
184 --------------------MESGNVS------------SSLFGNVSTAL-------RPE
185 -----------------------ARLSA---E---------------TRLL---------
186 --GWNVPPEELR--HIPEHWLTYPE-------------PPESMNYLLGTLYIFFTLMSML
187 GNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMM-VK-TPIFIYNSFH-QGYA--LGHLG
188 CQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPW-
189 VVACYTETWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTTMITY
190 YYSQIVGHVFSHEKALRDQAKKM------------------NVESLRS------------
191 ------------------------------------------------------------
192 -------------------------------------NVDKNKETAEIRIAKAAITICFL
193 FFCSWTPYGVMSLIGAF-GDKT-L-LTPGATMIPACACKMVACIDPFVYAISHPRYRMEL
194 QKRCPWL--ALNEKAPESSA----VASTST---TQEP-----------------------
195 ------------------------------------------------------------
196 ------------QQT-------TA-A
197 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
198 --------------------MEYHNVS------------SVL-GNVSSVL-------RPD
199 -----------------------ARLSA---E---------------SRLL---------
200 --GWNVPPDELR--HIPEHWLIYPE-------------PPESMNYLLGTLYIFFTVISMI
201 GNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMM-IK-TPIFIYNSFH-QGYA--LGHLG
202 CQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPW-
203 VVACYTESWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTTMITY
204 YYSQIVGHVFSHEKALRDQAKKM------------------NVDSLRS------------
205 ------------------------------------------------------------
206 -------------------------------------NVDKSKEAAEIRIAKAAITICFL
207 FFASWTPYGVMSLIGAF-GDKT-L-LTPGATMIPACTCKMVACIDPFVYAISHPRYRMEL
208 QKRCPWL--AISEKAPESRA----AISTST---TQEQ-----------------------
209 ------------------------------------------------------------
210 ------------QQT-------TA-A
211 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
212 --------------------ME------------------PLCNASEPPL-------RPE
213 -----------------------AR-SSGNGD---------------LQFL---------
214 --GWNVPPDQIQ--YIPEHWLTQLE-------------PPASMHYMLGVFYIFLFCASTV
215 GNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMC-LK-APIF--NSFH-RGFAIYLGNTW
216 CQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-
217 VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFFFSFVCPTLMILY
218 YYSQIVGHVFSHEKALREQAKKM------------------NVESLRS------------
219 ------------------------------------------------------------
220 -------------------------------------NVDKSKETAEIRIAKAAITICFL
221 FFVSWTPYGVMSLIGAF-GDKS-L-LTQGATMIPACTCKLVACIDPFVYAISHPRYRLEL
222 QKRCPWL--GVNEKSGEISS----AQSTTT---QEQ------------------------
223 ------------------------------------------------------------
224 ------------QQT-------TA-A
225 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
226 --------------------MD------------------ALCNASEPPL-------RPE
227 -----------------------ARMSSGSDE---------------LQFL---------
228 --GWNVPPDQIQ--YIPEHWLTQLE-------------PPASMHYMLGVFYIFLFFASTL
229 GNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMC-LK-APIFIYNSFH-RGFA--LGNTW
230 CQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-
231 VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFLFSFVVPTLMILY
232 YYSQIVGHVFNHEKALREQAKKM------------------NVESLRS------------
233 ------------------------------------------------------------
234 -------------------------------------NVDKSKETAEIRIAKAAITICFL
235 FFVSWTPYGVMSLIGAF-GDKS-L-LTPGATMIPACTCKLVACIEPFVYAISHPRYRMEL
236 QKRCPWL--GVNEKSGEASS----AQSTTT---QEQT-----------------------
237 ------------------------------------------------------------
238 ------------QQT-------SA-A
239 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
240 --------------------MT-------------------------NAT-------GPQ
241 MAYYG-----------------AASMDFGYPE---------------GVSI---------
242 --VDFVRPEIKP--YVHQHWYNYPP-------------VNPMWHYLLGVIYLFLGTVSIF
243 GNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVWM--FSPQY
244 CEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTGKAVVFALISWVIAIGC-
245 ALPPFFG-WG-----NYILEGILDSCSYDYLTQD--FNTFSYNIFIFVFDYFLPAAIIVF
246 SYVFIVKAIFAHEAAMRAQAKKM------------------NVSTLRS------------
247 ------------------------------------------------------------
248 --------------------------------------NEADAQRAEIRIAKTALVNVSL
249 WFICWTPYALISLKGVM-GDTS-G-ITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAI
250 TQHLPWF--CVHETETKSND----DSQSNS---TVAQ-----------------------
251 ------------------------------------------------------------
252 ----------------------DK-A
253 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
254 --------------------MA-------------------------NVT-------GPQ
255 MAFYG-----------------SGAATFGYPE---------------GMTV---------
256 --ADFVPDRVKH--MVLDHWYNYPP-------------VNPMWHYLLGVVYLFLGVISIA
257 GNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRWM--FSGTY
258 CEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQGKATFMCGLAWVISVGW-
259 SLPPFFG-WG-----SYTLEGILDSCSYDYFTRD--MNTITYNICIFIFDFFLPASVIVF
260 SYVFIVKAIFAHEAAMRAQAKKM------------------NVTNLRS------------
261 ------------------------------------------------------------
262 --------------------------------------NEAETQRAEIRIAKTALVNVSL
263 WFICWTPYAAITIQGLL-GNAE-G-ITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAI
264 TQHLPWF--CVHEKDPNDVE----ENQSSN---TQTQ-----------------------
265 ------------------------------------------------------------
266 ----------------------EK-S
267 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
268 --------------------ME-------------------SFAVAAAQL-------GPH
269 FA----------------------PLS--------------------NGSV---------
270 --VDKVTPDMAH--LISPYWNQFPA-------------MDPIWAKILTAYMIMIGMISWC
271 GNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMM
272 CDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKM-----------
273 ----------------YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICY
274 SYWFIIAAVSAHEKAMREQAKKM------------------NVKSLRS------------
275 ------------------------------------------------------------
276 --------------------------------------SEDAEKSAEGKLAKVALVTITL
277 WFMAWTPYLVINCMGLF-KF-E-G-LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLAL
278 KEKCPCC--VFGKVDDGKSS----DAQSQA-TASEAE-----------------------
279 ------------------------------------------------------------
280 ----------------------SK-A
281 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
282 --------------------ME-------------------SFAVAAAQL-------GPH
283 FA----------------------PLS--------------------NGSV---------
284 --VDKVTPDMAH--LISPYWNQFPA-------------MDPIWAKILTAYMIMIGMISWC
285 GNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMM
286 CDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSSIW-
287 CLAPAFG-WS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICY
288 SYWFIIAAVSAHEKAMREQAKKM------------------NVKSLRS------------
289 ------------------------------------------------------------
290 --------------------------------------SEDAEKSAEGKLAKVALVTITL
291 WFMAWTPYLVINCMGLF-KF-E-G-LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLAL
292 KEKCPCC--VFGKVDDGKSS----DAQSQA-TASEAE-----------------------
293 ------------------------------------------------------------
294 ----------------------SK-A
295 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
296 --------------------MD-------------------SFAAVATQL-------GPQ
297 FA----------------------APS--------------------NGSV---------
298 --VDKVTPDMAH--LISPYWDQFPA-------------MDPIWAKILTAYMIIIGMISWC
299 GNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMM
300 CDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSTIWC
301 CLAPVFG-WS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICY
302 SYWFIIAAVSAHEKAMREQAKKM------------------NVKSLRS------------
303 ------------------------------------------------------------
304 --------------------------------------SEDADKSAEGKLAKVALVTISL
305 WFMAWTPYLVINCMGLF-KF-E-G-LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLAL
306 KEKCPCC--VFGKVDDGKSS----EAQSQA-TTSEAE-----------------------
307 ------------------------------------------------------------
308 ----------------------SK-A
309 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
310 --------------------MERSHL--------------PETPFDLAHS-------GPR
311 FQ----------------------AQSSG------------------NGSV---------
312 --LDNVLPDMAH--LVNPYWSRFAP-------------MDPMMSKILGLFTLAIMIISCC
313 GNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLW
314 CDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKILFIWMMAVFW-
315 TVMPLIG-WS-----AYVPEGNLTACSIDYMTRM--WNPRSYLITYSLFVYYTPLFLICY
316 SYWFIIAAVAAHEKAMREQAKKM------------------NVKSLRS------------
317 ------------------------------------------------------------
318 --------------------------------------SEDCDKSAEGKLAKVALTTISL
319 WFMAWTPYLVICYFGLF-KI-D-G-LTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVL
320 KEKCPMC--VFGNTDEPKPD----APASDTETTSEAD-----------------------
321 ------------------------------------------------------------
322 ----------------------SK-A
323 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
324 --------------------MERSLL--------------PEPPLAMALL-------GPR
325 FE----------------------AQTGG------------------NRSV---------
326 --LDNVLPDMAP--LVNPHWSRFAP-------------MDPTMSKILGLFTLVILIISCC
327 GNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLW
328 CDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKIAFIWMMAVFW-
329 TIMPLIG-WS-----SYVPEGNLTACSIDYMTRQ--WNPRSYLITYSLFVYYTPLFMICY
330 SYWFIIATVAAHEKAMRDQAKKM------------------NVKSLRS------------
331 ------------------------------------------------------------
332 --------------------------------------SEDCDKSAENKLAKVALTTISL
333 WFMAWTPYLIICYFGLF-KI-D-G-LTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVL
334 KEKCPMC--VCGTTDEPKPD----APPSDTETTSEAE-----------------------
335 ------------------------------------------------------------
336 ----------------------SK-D
337 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
338 --------------------MI-------------------------AVS-------GPS
339 YE----------------------AFSYGGQA------------RFNNQTV---------
340 --VDKVPPDMLH--LIDANWYQYPP-------------LNPMWHGILGFVIGMLGFVSAM
341 GNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETWV--LGPLF
342 CQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSINGALIRIIAIWLFSLGW-
343 TIAPMFG-WN-----RYVPEGNMTACGTDYFNRG--LLSASYLVCYGIWVYFVPLFLIIY
344 SYWFIIQAVAAHEKNMREQAKKM------------------NVASLRS------------
345 ------------------------------------------------------------
346 --------------------------------------SENQNTSAECKLAKVALMTISL
347 WFMAWTPYLVINFSGIF-NL-V-K-ISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAAL
348 FAKFPSL--AC-AAEPSSDA----VSTTSG-TTTVTDN----------------------
349 ------------------------------------------------------------
350 ------------EK--------SN-A
351 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
352 --------------------M---------------------------AN-------QLS
353 YS----------------------SLGWPYQP---------------NASV---------
354 --VDTMPKEMLY--MIHEHWYAFPP-------------MNPLWYSILGVAMIILGIICVL
355 GNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETWI--LGPFM
356 CEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHKKATLLLLFVWIWSGGW-
357 TILPFFG-WS-----RYVPEGNLTSCTVDYLTKD--WSSASYVVIYGLAVYFLPLITMIY
358 CYFFIVHAVAEHEKQLREQAKKM------------------NVASLRA------------
359 ------------------------------------------------------------
360 -------------------------------------NADQQKQSAECRLAKVAMMTVGL
361 WFMAWTPYLIISWAGVF-SSGT-R-LTPLATIWGSVFAKANSCYNPIVYGISHPRYKAAL
362 YQRFPSL--ACGSGESGSDV----KSEASA-TTTMEEK----------------------
363 ------------------------------------------------------------
364 ------------PKI-------PE-A
365 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
366 --------------------MV-------------------------EST-------TL-
367 -----------------------VNQTWWY-----------------NPTV---------
368 --------------DIHPHWAKFDP-------------IPDAVYYSVGIFIGVVGIIGIL
369 GNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI--FGKVA
370 CQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVW-
371 SVGPVFN-WG-----AYVPEGILTSCSFDYLSTD--PSTRSFILCMYFCGFMLPIIIIAF
372 CYFNIVMSVSNHEKEMAAMAKRL------------------NAKELRK------------
373 ------------------------------------------------------------
374 --------------------------------------AQ-AGASAEMKLAKISMVIITQ
375 FMLSWSPYAIIALLAQF-GPAE-W-VTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAI
376 QTTFPWLLTCCQFDEKECED----ANDAEE-EVVASER--GGESRDAAQMKEMMAMMQKM
377 QAQQAAYQP---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQV
378 EAPQGAPPQGVDNQA-------YQ-A
379 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
380 --------------------MG-------------------------RDL-------R--
381 -----------------------DNETWWY-----------------NPSI---------
382 --------------VVHPHWREFDQ-------------VPDAVYYSLGIFIGICGIIGCG
383 GNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI--FGFAA
384 CKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLW-
385 AIGPIFG-WG-----AYTLEGVLCNCSFDYISRD--STTRSNILCMFILGFFGPILIIFF
386 CYFNIVMSVSNHEKEMAAMAKRL------------------NAKELRK------------
387 ------------------------------------------------------------
388 --------------------------------------AQ-AGANAEMRLAKISIVIVSQ
389 FLLSWSPYAVVALLAQF-GPLE-W-VTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAI
390 SQTFPWVLTCCQFDDKETED----DKDAET-EIPAGESSDAAPSADAAQMKEMMAMMQKM
391 QQQQAAYPPQGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP--
392 ----AAPPQGVDNQA-------YQ-A
393 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
394 --------------------M---------MDV-NSSGRPDLYGHLRSFLLPEVGRGLPD
395 LSPDG------------GADPVAGS--------------------------WAPHLLS--
396 -EVTAS---------PAPTW---DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIA
397 GNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFF
398 CNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-
399 TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLF
400 MYYQIYKAARKSAAKHKF--------------PGFPRVEPDSVIALNG------------
401 ----------------------------------------IVKLQKE-------------
402 -----VEECAN------------------LSRLLKHERKNISIFKREQKAATTLGIIVGA
403 FTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTY
404 RSLL-----QCQYRNINRKL----SAAGMHEALKLAER---------------------P
405 ERPEFVLQNA--------------------------------------------------
406 --------DYCRKKG-------HD-S
407 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
408 ------------------------------------------------------------
409 ----------------------------------------------------MPHLLSGF
410 LEVTAS---------PAPTW---DAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIA
411 GNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFF
412 CNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-
413 TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLF
414 MYYQIYKAARKSAAKHKF--------------PGFPRVQPESVISLNG------------
415 ----------------------------------------VVKLQKE-------------
416 -----VEECAN------------------LSRLLKHERKNISIFKREQKAATTLGIIVGA
417 FTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTS
418 RSLL-----QCQYRNINRKL----SAAGMHEALKLAER---------------------P
419 ERSEFVLQNS--------------------------------------------------
420 --------DHCGKKG-------HD-T
421 > 31=p A47425 serotonin receptor 5HT-7 - rat
422 ------------------------------------------------------------
423 ----------------------------------------------------MPHLLSGF
424 LEVTAS---------PAPTW---DAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIA
425 GNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFF
426 CNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-
427 TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLF
428 MYYQIYKAARKSAAKHKF--------------PGFPRVQPESVISLNG------------
429 ----------------------------------------VVKLQKE-------------
430 -----VEECAN------------------LSRLLKHERKNISIFKREQKAATTLGIIVGA
431 FTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTY
432 RSLL-----QCQYRNINRKL----SAAGMHEALKLAER---------------------P
433 ERSEFVLQNS--------------------------------------------------
434 --------DHCGKKG-------HD-T
435 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
436 --------------------MDVLSPG---------------------------------
437 ---------------------------------------------QGNNT----------
438 -TSPPAPF------ETGGNTTGISD-------------VTVSYQVITSLLLGTLIFCAVL
439 GNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVT
440 CDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-
441 SIPPMLG-WRTPEDRSDPD---ACTISKDH----------GYTIYSTFGAFYIPLLLMLV
442 LYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKK-----SVNG--ESGSRNWRLG
443 VESKAGGALCANGAVRQGDDGAAL--EVIEVHRVGNSKEHLPLPSEAGPTPCAPAS----
444 --------------FERKNERNA-------------EAKRKMALARERKTVKTLGIIMGT
445 FILCWLPFFIVALVLPF-CESSCH-MPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAF
446 KKII-----KCKF-----------------------------------------------
447 ------------------------------------------------------------
448 ----------CR-------------Q
449 > 33=p A35181 serotonin receptor class 1A - rat
450 --------------------MDVFSFG---------------------------------
451 ---------------------------------------------QGNNT----------
452 -TASQEPF------GTGGNVTSISD-------------VTFSYQVITSLLLGTLIFCAVL
453 GNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVT
454 CDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-
455 SIPPMLG-WRTPEDRSDPD---ACTISKDH----------GYTIYSTFGAFYIPLLLMLV
456 LYGRIFRAARFRIRKTVRKVEKKGAGTSLGTSSAPPPKK-----SLNG--QPGSGDWRRC
457 AENRAVGTPCTNGAVRQGDDEATL--EVIEVHRVGNSKEHLPLPSESGSNSYAPAC----
458 --------------LERKNERNA-------------EAKRKMALARERKTVKTLGIIMGT
459 FILCWLPFFIVALVLPF-CESSCH-MPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAF
460 KKII-----KCKF-----------------------------------------------
461 ------------------------------------------------------------
462 ----------CR-------------R
463 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
464 --------------------MANFTFGDLALDVARMGGLASTPSGLRS-----TGLTTPG
465 LSPTGLVTSDFNDSYGLTGQFINGSHSSRSRD-----------NASANDT----------
466 -SATNM---------TDDRYWSLTV-------------YSHEHLVLTSVILGLFVLCCII
467 GNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEV
468 CDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-
469 SIPPLFG-WRDPNN--DPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLVMMI
470 IYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKK
471 RRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCAEEA
472 SIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLAIITGA
473 FLICWLPFFIIALIGPF-VDPE-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAF
474 QKIL-----FGKY-----------------------------------------------
475 ------------------------------------------------------------
476 ----------RR----------GH-R
477 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
478 --------------------MANFTFGDLALDVARMGGLASTPSGLRS-----TGLTTPG
479 LSPTGLVTSDFNDSYGLTGQFINGSHSSRSRD-----------NASANDT----------
480 -SATNM---------TDDRYWSLTV-------------YSHEHLVLTSVILGLFVLCCII
481 GNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEV
482 CDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-
483 SIPPLFG-WRDPNN--DPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLVMMI
484 IYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKK
485 RRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCAEEA
486 SIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLAIITGA
487 FLICWLPFFIIALIGPF-VDPE-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAF
488 QKIL-----FGKY-----------------------------------------------
489 ------------------------------------------------------------
490 ----------RR----------GH-R
491 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
492 --------------------M---------------------------------------
493 ----------------------EGAEGQEELDWEALYLRLPLQNCSWNSTGWEPN-----
494 WNVTVV---------PNTTWWQASAPFDT--------PAALVRAAAKAVVLGLLILATVV
495 GNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRWT--LGPEL
496 CDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTVSFFV-
497 CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSFYVPVLIILI
498 LYWRIYQTARKRIRR------RRGATARGGVGPPPVPAG---------------------
499 ------------GALVAGGGSGGIAAAVVAV-----IGRPLPTISETTTTGFTNVSSNNT
500 SPE--KQSCANGLEADPPTTGYGAVAAAYYPSLVRRKPKEAADSKRERKAAKTLAIITGA
501 FVACWLPFFVLAILVPT-CD--CE-VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAF
502 QRLL-----CGRR-----------------------------------------------
503 ------------------------------------------------------------
504 ----------VRRRR-------AP-Q
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