1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 M-----------------------------------------------------------
3 ------------------------------NGTE--GDNFYV----PF------------
4 --------------------------SNKTGLARSPYEYPQY-YLA-----EPWK-----
5 ----YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-F
6 TVTMYTS-MN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-F
7 RFGNTHAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFN
8 NESYVVYMFVVHFLVPFVIIFFCYGRLLCTV----KEAAAAQQE----------------
9 ------------------------------------------------------------
10 ------------------------------------------------------------
11 ---------------------------------------------SASTQKAEKEVTRMV
12 VLMVIGFLVCWVPYASVAFYIFT-HQG-S--DFGATFMTLPAFFAKSSALYNPVIYILMN
13 KQFRNCMITTLC-C---GKNP------------------------------LGDDE--SG
14 ASTSKT-E--VSSVS-TSPV----------------------------------------
15 ---------------------------------------------SP-A---
16 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
17 M-----------------------------------------------------------
18 ------------------------------NGTE--GPNFYV----PF------------
19 --------------------------SNITGVVRSPFEQPQY-YLA-----EPWQ-----
20 ----FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-F
21 TTTLYTS-LH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-F
22 RFGENHAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVN
23 NESFVIYMFVVHFTIPMIVIFFCYGQLVFTV----KEAAAQQQE----------------
24 ------------------------------------------------------------
25 ------------------------------------------------------------
26 ---------------------------------------------SATTQKAEKEVTRMV
27 IIMVIFFLICWLPYASVAMYIFT-HQG-S--NFGPIFMTLPAFFAKTASIYNPIIYIMMN
28 KQFRNCMLTSLC-C---GKNP------------------------------LGDDE--AS
29 ATASKT-E--------TSQV----------------------------------------
30 ---------------------------------------------AP-A---
31 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
32 M-----------------------------------------------------------
33 ------------------------------NGTE--GINFYV----PM------------
34 --------------------------SNKTGVVRSPFEYPQY-YLA-----EPWK-----
35 ----YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-F
36 TVTFYTA-WN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-F
37 RFSATHAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYH
38 NESYVLYMFVIHFIIPVVVIFFSYGRLICKV----REAAAQQQE----------------
39 ------------------------------------------------------------
40 ------------------------------------------------------------
41 ---------------------------------------------SATTQKAEKEVTRMV
42 ILMVLGFMLAWTPYAVVAFWIFT-NKG-A--DFTATLMAVPAFFSKSSSLYNPIIYVLMN
43 KQFRNCMITTIC-C---GKNP------------------------------FGDEDVSST
44 VSQSKT-E--VSSVS-SSQV----------------------------------------
45 ---------------------------------------------SP-A---
46 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
47 M-----------------------------------------------------------
48 ------------------------------NGTE--GKNFYV----PM------------
49 --------------------------SNRTGLVRSPFEYPQY-YLA-----EPWQ-----
50 ----FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-F
51 TVTFYTA-IN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-F
52 KFSSSHAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYN
53 NESYVIYMFVCHFILPVAVIFFTYGRLVCTV----KAAAAQQQD----------------
54 ------------------------------------------------------------
55 ------------------------------------------------------------
56 ---------------------------------------------SASTQKAEREVTKMV
57 ILMVFGFLIAWTPYATVAAWIFF-NKG-A--DFSAKFMAIPAFFSKSSALYNPVIYVLLN
58 KQFRNCMLTTIF-C---GKNP------------------------------LGDDE-SST
59 VSTSKT-E--VSS------V----------------------------------------
60 ---------------------------------------------SP-A---
61 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
62 M-----------------------------------------------------------
63 ------------------------------NGTE--GNNFYV----PL------------
64 --------------------------SNRTGLVRSPFEYPQY-YLA-----EPWQ-----
65 ----FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-F
66 TVTFYTA-IN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-F
67 KFSSTHASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYN
68 NESYVLYMFICHFILPVTIIFFTYGRLVCTV----KAAAAQQQD----------------
69 ------------------------------------------------------------
70 ------------------------------------------------------------
71 ---------------------------------------------SASTQKAEREVTKMV
72 ILMVLGFLVAWTPYATVAAWIFF-NKG-A--AFSAQFMAIPAFFSKTSALYNPVIYVLLN
73 KQFRSCMLTTLF-C---GKNP------------------------------LGDEE-SST
74 VSTSKT-E--VSS------V----------------------------------------
75 ---------------------------------------------SP-A---
76 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
77 M-----------------------------------------------------------
78 ------------------------------KQVPEFHEDFYI----PIPL----------
79 ------------------------DINNLS--AYSPFLVPQD-HLG-----NQGI-----
80 ----FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-S
81 PLSFYSF-FN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-F
82 TFKTPHAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYN
83 NESYVMFLFCFCFAVPFGTIVFCYGQLLITL----KLAAKAQAD----------------
84 ------------------------------------------------------------
85 ------------------------------------------------------------
86 ---------------------------------------------SASTQKAEREVTKMV
87 VVMVLGFLVCWAPYASFSLWIVS-HRG-E--EFDLRMATIPSCLSKASTVYNPVIYVLMN
88 KQFRSCMM-KMV-C---GKN-------------------------------IEEDE--AS
89 TSSQVT-Q--VSS------V----------------------------------------
90 ---------------------------------------------APEK---
91 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
92 M-----------------------------------------------------------
93 ------------------------------RKMS--EEEFYL-------F----------
94 --------------------------KNISSV--GPWDGPQY-HIA-----PVWA-----
95 ----FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-V
96 FPVFVAS-CN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-F
97 RFSSKHALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYR
98 SESYTWFLFIFCFIVPLSLICFSYTQLLRAL----KAVAAQQQE----------------
99 ------------------------------------------------------------
100 ------------------------------------------------------------
101 ---------------------------------------------SATTQKAEREVSRMV
102 VVMVGSFCVCYVPYAAFAMYMVN-NRN-H--GLDLRLVTIPSFFSKSACIYNPIIYCFMN
103 KQFQACIM-KMV-C---GKA-------------------------------MTDES--DT
104 CSSQKT-E--VSTVS-STQV----------------------------------------
105 ---------------------------------------------GP-N---
106 > 8=opsin, greensensitive human (fragment) S07060
107 ------------------------------------------------------------
108 ------------------------------------------------------------
109 ------------------------------------------------------------
110 --------------------------------------------------DLAETVIA-S
111 TISIVNQ-VS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-V
112 RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPG
113 VQSYMIVLMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQKE----------------
114 ------------------------------------------------------------
115 ------------------------------------------------------------
116 ---------------------------------------------SESTQKAEKEVTRMV
117 VVMVLAFC----------------------------------------------------
118 ------------------------------------------------------------
119 ------------------------------------------------------------
120 ----------------------------------------------------
121 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
122 M-------------AQQWSLQRLA--GRHPQDSYE-------------------------
123 ------------------------------DSTQ--SSIFTY----TN------------
124 --------------------------SNST---RGPFEGPNY-HIA-----PRWV-----
125 ----YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-S
126 TISVVNQ-VY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-V
127 RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPG
128 VQSYMIVLMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQKE----------------
129 ------------------------------------------------------------
130 ------------------------------------------------------------
131 ---------------------------------------------SESTQKAEKEVTRMV
132 VVMVLAFCFCWGPYAFFACFAAA-NPG-Y--PFHPLMAALPAFFAKSATIYNPVIYVFMN
133 RQFRNCIL-QLF-----GKK-------------------------------VDDGS--EL
134 SSASKT-E--VSSV---SSV----------------------------------------
135 ---------------------------------------------SP-A---
136 > 10== Z68193 1 human Red Opsin <>[]
137 M-------------AQQWSLQRLA--GRHPQDSYE-------------------------
138 ------------------------------DSTQ--SSIFTY----TN------------
139 --------------------------SNST---RGPFEGPNY-HIA-----PRWV-----
140 ----YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-S
141 TISIVNQ-VS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-V
142 RFDAKLAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPG
143 VQSYMIVLMVTCCIIPLAIIMLCYLQVWLAI----RAVAKQQKE----------------
144 ------------------------------------------------------------
145 ------------------------------------------------------------
146 ---------------------------------------------SESTQKAEKEVTRMV
147 VVMIFAYCVCWGPYTFFACFAAA-NPG-Y--AFHPLMAALPAYFAKSATIYNPVIYVFMN
148 RQFRNCIL-QLF-----GKK-------------------------------VDDGS--EL
149 SSASKT-E--VSSV---SSV----------------------------------------
150 ---------------------------------------------SP-A---
151 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
152 M-------------TEAWNVAVFA--ARRSRDD-D-------------------------
153 ------------------------------DTTR--GSVFTY----TN------------
154 --------------------------TNNT---RGPFEGPNY-HIA-----PRWV-----
155 ----YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-S
156 TISVFNQ-IF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-I
157 KFDSKLAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELG
158 CQSFMLTLMITCCFLPLFIIIVCYLQVWMAI----RAVAAQQKE----------------
159 ------------------------------------------------------------
160 ------------------------------------------------------------
161 ---------------------------------------------SESTQKAEREVSRMV
162 VVMIVAFCICWGPYASFVSFAAA-NPG-Y--AFHPLAAALPAYFAKSATIYNPVIYVFMN
163 RQFRNCIM-QLF-----GKK-------------------------------VDDGS--EA
164 STTSRT-E--VSSVS-NSSV----------------------------------------
165 ---------------------------------------------AP-A---
166 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
167 M-------------AA-WEAAFAA--RRRHEE--E-------------------------
168 ------------------------------DTTR--DSVFTY----TN------------
169 --------------------------SNNT---RGPFEGPNY-HIA-----PRWV-----
170 ----YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-S
171 TISVINQ-IS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-I
172 KFDGKLAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPG
173 VQSYMVVLMVTCCFFPLAIIILCYLQVWLAI----RAVAAQQKE----------------
174 ------------------------------------------------------------
175 ------------------------------------------------------------
176 ---------------------------------------------SESTQKAEKEVSRMV
177 VVMIVAYCFCWGPYTFFACFAAA-NPG-Y--AFHPLAAALPAYFAKSATIYNPIIYVFMN
178 RQFRNCIL-QLF-----GKK-------------------------------VDDGS--EV
179 ST-SRT-E--VSSVS-NSSV----------------------------------------
180 ---------------------------------------------SP-A---
181 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
182 M-------------S-------------------S-------------------------
183 ------------------------------NSSQ--AP----------------------
184 --------------------------PNGT---PGPFDGPQWPYQA-----PQST-----
185 ----YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-S
186 SVSLSNN-IN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-F
187 QFQRRHAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGSNN-
188 -NSYILSLFVTCFVLPLSLILFSYTNLLLTL----RAAAAQQKE----------------
189 ------------------------------------------------------------
190 ------------------------------------------------------------
191 ---------------------------------------------ADTTQRAEREVTRMV
192 IVMVMAFLLCWLPYSTFALVVAT-HKG-I--IIQPVLASLPSYFSKTATVYNPIIYVFMN
193 KQFQSCLL-EMLCCGYQPQR-------------------------------TGKAS--PG
194 TPGPHA-D--VTAAGLRNKV----------------------------------------
195 ---------------------------------------------MP-AHPV
196 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
197 M---------------------------------ES-G----------------------
198 ------------------------------NVSS---------------SLFGNVSTALR
199 PEARLSA---ETRLLGWNVPPEELR------------------HIP-----EHWLTYPEP
200 PESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--T
201 PIFIYNS-FH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--
202 KMTHGKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFD
203 TRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK----------------
204 ------------------------------------------------------------
205 ------------------------------------------------------------
206 -------------MNVESL---------------------RS-NVDKNKETAEIRIAKAA
207 ITICFLFFCSWTPYGVMSLIGAF-GDK-T--LLTPGATMIPACACKMVACIDPFVYAISH
208 PRYRMELQ---------KRCP------------------WLALNEKAPE--SSAVA--ST
209 STTQEP-Q-------------------------QT-------------------------
210 ---------------------------------------------TA-A---
211 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
212 M---------------------------------EY-H----------------------
213 ------------------------------NVSS---------------VL-GNVSSVLR
214 PDARLSA---ESRLLGWNVPPDELR------------------HIP-----EHWLIYPEP
215 PESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--T
216 PIFIYNS-FH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--
217 KMTHGKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFD
218 TRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK----------------
219 ------------------------------------------------------------
220 ------------------------------------------------------------
221 -------------MNVDSL---------------------RS-NVDKSKEAAEIRIAKAA
222 ITICFLFFASWTPYGVMSLIGAF-GDK-T--LLTPGATMIPACTCKMVACIDPFVYAISH
223 PRYRMELQ---------KRCP------------------WLAISEKAPE--SRAAI--ST
224 STTQEQ-Q-------------------------QT-------------------------
225 ---------------------------------------------TA-A---
226 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
227 M---------------------------------EPLC----------------------
228 ------------------------------NASE---------------PP-------LR
229 PEAR-SSGNGDLQFLGWNVPPDQIQ------------------YIP-----EHWLTQLEP
230 PASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--A
231 PIF--NS-FH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--
232 NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFD
233 TRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKK----------------
234 ------------------------------------------------------------
235 ------------------------------------------------------------
236 -------------MNVESL---------------------RS-NVDKSKETAEIRIAKAA
237 ITICFLFFVSWTPYGVMSLIGAF-GDK-S--LLTQGATMIPACTCKLVACIDPFVYAISH
238 PRYRLELQ---------KRCP------------------WLGVNEKSGE--ISSAQ--ST
239 -TTQEQ-Q-------------------------QT-------------------------
240 ---------------------------------------------TA-A---
241 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
242 M---------------------------------DALC----------------------
243 ------------------------------NASE---------------PP-------LR
244 PEARMSSGSDELQFLGWNVPPDQIQ------------------YIP-----EHWLTQLEP
245 PASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--A
246 PIFIYNS-FH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--
247 NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFD
248 TRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKK----------------
249 ------------------------------------------------------------
250 ------------------------------------------------------------
251 -------------MNVESL---------------------RS-NVDKSKETAEIRIAKAA
252 ITICFLFFVSWTPYGVMSLIGAF-GDK-S--LLTPGATMIPACTCKLVACIEPFVYAISH
253 PRYRMELQ---------KRCP------------------WLGVNEKSGE--ASSAQ--ST
254 -TTQEQTQ-------------------------QT-------------------------
255 ---------------------------------------------SA-A---
256 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
257 M---------------------------------------------TNATGPQMAYYG--
258 ---AASMDFGYPE-----------------GVSI---------------VD---------
259 -----------------FVRPEIKP------------------YVH-----QHWYNYPPV
260 NPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-V
261 PFFTYNC-FSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-P
262 KLTTGKAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFN
263 TFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKK----------------
264 ------------------------------------------------------------
265 ------------------------------------------------------------
266 -------------MNVSTL---------------------RS-N-EADAQRAEIRIAKTA
267 LVNVSLWFICWTPYALISLKGVM-GDT-S--GITPLVSTLPALLAKSCSCYNPFVYAISH
268 PKYRLAIT---------QHLP------------------WFCVHETETKS-NDDSQ--SN
269 STVAQ-------------------------------------------------------
270 ---------------------------------------------DK-A---
271 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
272 M---------------------------------------------ANVTGPQMAFYG--
273 ---SGAATFGYPE-----------------GMTV---------------AD---------
274 -----------------FVPDRVKH------------------MVL-----DHWYNYPPV
275 NPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-F
276 PPFCYNC-FSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-P
277 KLTQGKATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMN
278 TITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKK----------------
279 ------------------------------------------------------------
280 ------------------------------------------------------------
281 -------------MNVTNL---------------------RS-N-EAETQRAEIRIAKTA
282 LVNVSLWFICWTPYAAITIQGLL-GNA-E--GITPLLTTLPALLAKSCSCYNPFVYAISH
283 PKFRLAIT---------QHLP------------------WFCVHEKDPND-VEENQ--SS
284 NTQTQ-------------------------------------------------------
285 ---------------------------------------------EK-S---
286 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
287 M---------------------------------E------SFAVAAAQLGPHFAPLS--
288 ------------------------------NGSV---------------VD---------
289 -----------------KVTPDMAH------------------LIS-----PYWNQFPAM
290 DPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-T
291 PMMGINL-YF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-R
292 PMTIPLALGKM---------------------------YVPEGNLTSCGIDYLE--RDWN
293 PRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK----------------
294 ------------------------------------------------------------
295 ------------------------------------------------------------
296 -------------MNVKSL---------------------RS-S-EDAEKSAEGKLAKVA
297 LVTITLWFMAWTPYLVINCMGLF--KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISH
298 PKYRLALK---------EKCP------------------CCVFGKVDDGK-SSDAQ--SQ
299 ATASEA-E----------------------------------------------------
300 ---------------------------------------------SK-A---
301 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
302 M---------------------------------E------SFAVAAAQLGPHFAPLS--
303 ------------------------------NGSV---------------VD---------
304 -----------------KVTPDMAH------------------LIS-----PYWNQFPAM
305 DPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-T
306 PMMGINL-YF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-R
307 PMTIPLALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWN
308 PRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK----------------
309 ------------------------------------------------------------
310 ------------------------------------------------------------
311 -------------MNVKSL---------------------RS-S-EDAEKSAEGKLAKVA
312 LVTITLWFMAWTPYLVINCMGLF--KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISH
313 PKYRLALK---------EKCP------------------CCVFGKVDDGK-SSDAQ--SQ
314 ATASEA-E----------------------------------------------------
315 ---------------------------------------------SK-A---
316 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
317 M---------------------------------D------SFAAVATQLGPQFAAPS--
318 ------------------------------NGSV---------------VD---------
319 -----------------KVTPDMAH------------------LIS-----PYWDQFPAM
320 DPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-T
321 PMMGINL-YF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-R
322 PMTIPLALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWN
323 PRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK----------------
324 ------------------------------------------------------------
325 ------------------------------------------------------------
326 -------------MNVKSL---------------------RS-S-EDADKSAEGKLAKVA
327 LVTISLWFMAWTPYLVINCMGLF--KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISH
328 PKYRLALK---------EKCP------------------CCVFGKVDDGK-SSEAQ--SQ
329 ATTSEA-E----------------------------------------------------
330 ---------------------------------------------SK-A---
331 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
332 M---------------------------------ER-SHLPETPFDLAHSGPRFQAQS--
333 ---SG-------------------------NGSV---------------LD---------
334 -----------------NVLPDMAH------------------LVN-----PYWSRFAPM
335 DPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-S
336 PVMIINF-YY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-T
337 PMTIKTSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWN
338 PRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKK----------------
339 ------------------------------------------------------------
340 ------------------------------------------------------------
341 -------------MNVKSL---------------------RS-S-EDCDKSAEGKLAKVA
342 LTTISLWFMAWTPYLVICYFGLF--KI-D--GLTPLTTIWGATFAKTSAVYNPIVYGISH
343 PKYRIVLK---------EKCP------------------MCVFGNTDEPKPDAPAS--DT
344 ETTSEA-D----------------------------------------------------
345 ---------------------------------------------SK-A---
346 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
347 M---------------------------------ER-SLLPEPPLAMALLGPRFEAQT--
348 ---GG-------------------------NRSV---------------LD---------
349 -----------------NVLPDMAP------------------LVN-----PHWSRFAPM
350 DPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-S
351 PVMIINF-YY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-T
352 PMTIKTSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWN
353 PRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKK----------------
354 ------------------------------------------------------------
355 ------------------------------------------------------------
356 -------------MNVKSL---------------------RS-S-EDCDKSAENKLAKVA
357 LTTISLWFMAWTPYLIICYFGLF--KI-D--GLTPLTTIWGATFAKTSAVYNPIVYGISH
358 PNDRLVLK---------EKCP------------------MCVCGTTDEPKPDAPPS--DT
359 ETTSEA-E----------------------------------------------------
360 ---------------------------------------------SK-D---
361 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
362 M---------------------------------------------IAVSGPSYEAFS--
363 ---YG----GQAR---------------FNNQTV---------------VD---------
364 -----------------KVPPDMLH------------------LID-----ANWYQYPPL
365 NPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-S
366 PPMVINC-YY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-K
367 PLSINGALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLL
368 SASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKK----------------
369 ------------------------------------------------------------
370 ------------------------------------------------------------
371 -------------MNVASL---------------------RS-S-ENQNTSAECKLAKVA
372 LMTISLWFMAWTPYLVINFSGIF--NL-V--KISPLFTIWGSLFAKANAVYNPIVYGISH
373 PKYRAALF---------AKFP------------------SLAC-AAEPSS-DAVST--TS
374 GTTTVT-D----------------------------------------------------
375 -----------------------------------------NEK-SN-A---
376 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
377 M-----------------------------------------------ANQLSYSSLG--
378 ---WP----YQP------------------NASV---------------VD---------
379 -----------------TMPKEMLY------------------MIH-----EHWYAFPPM
380 NPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-M
381 PTMTSNC-FA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-A
382 PLTHKKATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWS
383 SASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKK----------------
384 ------------------------------------------------------------
385 ------------------------------------------------------------
386 -------------MNVASL---------------------RANA-DQQKQSAECRLAKVA
387 MMTVGLWFMAWTPYLIISWAGVF--SSGT--RLTPLATIWGSVFAKANSCYNPIVYGISH
388 PRYKAALY---------QRFP------------------SLACGSGESGS-DVKSE--AS
389 ATTTME-E----------------------------------------------------
390 -----------------------------------------KPKIPE-A---
391 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
392 M-----------------------------------------------------------
393 ---------VESTTLVNQTW-------WY-NPTV---------------D----------
394 --------------------------------------------IH-----PHWAKFDPI
395 PDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGF
396 PLKTISA-FM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASK
397 KMSHRRAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPS
398 TRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKR----------------
399 ------------------------------------------------------------
400 ------------------------------------------------------------
401 -------------LNAKEL---------------------RK---AQAGASAEMKLAKIS
402 MVIITQFMLSWSPYAIIALLAQF-GPA-E--WVTPYAAELPVLFAKASAIHNPIVYSVSH
403 PKFREAIQ---------TTFPWL--------------LTCCQFDEKECED-ANDAE--EE
404 VVASER---GGESRD-AAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQGAYP
405 PPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQA-YQ-A---
406 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
407 M-----------------------------------------------------------
408 ---------GRDLR-DNETW-------WY-NPSI---------------V----------
409 --------------------------------------------VH-----PHWREFDQV
410 PDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGF
411 PLMTISC-FL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASK
412 KMSHRRAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDST
413 TRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKR----------------
414 ------------------------------------------------------------
415 ------------------------------------------------------------
416 -------------LNAKEL---------------------RK---AQAGANAEMRLAKIS
417 IVIVSQFLLSWSPYAVVALLAQF-GPL-E--WVTPYAAQLPVMFAKASAIHNPMIYSVSH
418 PKFREAIS---------QTFPWV--------------LTCCQFDDKETED-DKDAE--TE
419 IPAGES-SDAAPSAD-AAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQGY--
420 PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQA-YQ-A---
421 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
422 MMDVNSSGRPDL----YGHLRSFL--LPE-----------------VGRGLPDLSPDGGA
423 DPVAG-------------SWAPHLLS----EVTA--SPAPTW------------------
424 -----------------DAPPDNAS-GCGE-------------QIN-------------Y
425 GRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-M
426 PFVSVTDLIG-GKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV
427 RQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF--------
428 --GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF-------------
429 ----PGF---------------------------------PRVEPDS-------------
430 --------VIALNGIVKLQKEV--------------------------------------
431 --------EE--CANLSRLLKH------------------ER-K-NISIFKREQKAATTL
432 GIIVGAFTVCWLPFFLLSTARPFICGT-SCSCIPLWVERTFLWLGYANSLINPFIYAFFN
433 RDLRTTYR-SLL----------QC---QYRNINRKLSA-------------AGMHE--AL
434 KLAERP-E--------RPEF-----VL------QN-------------------------
435 ------ADYCRKKGHD--------------------------------S---
436 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
437 M-----------------------------------------------------------
438 ---------------------PHLLSGFL-EVTA--SPAPTW------------------
439 -----------------DAPPDNVS-GCGE-------------QIN-------------Y
440 GRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-M
441 PFVSVTDLIG-GKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV
442 RQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF--------
443 --GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF-------------
444 ----PGF---------------------------------PRVQPES-------------
445 --------VISLNGVVKLQKEV--------------------------------------
446 --------EE--CANLSRLLKH------------------ER-K-NISIFKREQKAATTL
447 GIIVGAFTVCWLPFFLLSTARPFICGT-SCSCIPLWVERTCLWLGYANSLINPFIYAFFN
448 RDLRPTSR-SLL----------QC---QYRNINRKLSA-------------AGMHE--AL
449 KLAERP-E--------RSEF-----VL------QN-------------------------
450 ------SDHCGKKGHD--------------------------------T---
451 > 31=p A47425 serotonin receptor 5HT-7 - rat
452 M-----------------------------------------------------------
453 ---------------------PHLLSGFL-EVTA--SPAPTW------------------
454 -----------------DAPPDNVS-GCGE-------------QIN-------------Y
455 GRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-M
456 PFVSVTDLIG-GKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV
457 RQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF--------
458 --GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF-------------
459 ----PGF---------------------------------PRVQPES-------------
460 --------VISLNGVVKLQKEV--------------------------------------
461 --------EE--CANLSRLLKH------------------ER-K-NISIFKREQKAATTL
462 GIIVGAFTVCWLPFFLLSTARPFICGT-SCSCIPLWVERTCLWLGYANSLINPFIYAFFN
463 RDLRTTYR-SLL----------QC---QYRNINRKLSA-------------AGMHE--AL
464 KLAERP-E--------RSEF-----VL------QN-------------------------
465 ------SDHCGKKGHD--------------------------------T---
466 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
467 M-DVLSPGQ-----------------GNN-----------------TTSPPAPFETGG--
468 ------------------------------NTTG--ISDVTV------------------
469 ------------------------------------------------------------
470 --SYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-L
471 PMAALYQ-VL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVN
472 KRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH--------
473 --GYTIYSTFGAFYIPLLLMLVLYGRIF-------RAARFRIRK----------------
474 -----------------------TVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRL
475 GVESKAGGALCANGAVRQGDDG----AALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASF
476 ERKN----ERN--------------------A--------EA-K-RKMALARERKTVKTL
477 GIIMGTFILCWLPFFIVALVLPF-CES-SC-HMPTLLGAIINWLGYSNSLLNPVIYAYFN
478 KDFQNAFK-KII---------------KCKFCRQ--------------------------
479 ------------------------------------------------------------
480 ----------------------------------------------------
481 > 33=p A35181 serotonin receptor class 1A - rat
482 M-DVFSFGQ-----------------GNN-----------------TTASQEPFGTGG--
483 ------------------------------NVTS--ISDVTF------------------
484 ------------------------------------------------------------
485 --SYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-L
486 PMAALYQ-VL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVN
487 KRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH--------
488 --GYTIYSTFGAFYIPLLLMLVLYGRIF-------RAARFRIRK----------------
489 -----------------------TVRKVEKKGAGTSLGTSSAPPPKKSLNGQPGSGDWRR
490 CAENRAVGTPCTNGAVRQGDDE----ATLEVIEVHRVGNSKEHLPLPSESGSNSYAPACL
491 ERKN----ERN--------------------A--------EA-K-RKMALARERKTVKTL
492 GIIMGTFILCWLPFFIVALVLPF-CES-SC-HMPALLGAIINWLGYSNSLLNPVIYAYFN
493 KDFQNAFK-KII---------------KCKFCRR--------------------------
494 ------------------------------------------------------------
495 ----------------------------------------------------
496 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
497 M-ANFTFGDLALDVARMGGLASTPSGLRS-----------------TGLTTPGLSPTG--
498 ------------------------------LVTS--DFNDSYGLTGQF-IN-GSHS----
499 -----------------SRSRDNAS-ANDT-------------SATNMTDDRYWS-LTVY
500 SHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-M
501 PLSVVSE-IS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIR
502 RRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK--------
503 --GYTIFSTVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETT
504 LVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKK-------------
505 ---NRAKKLPENANGVNSNSSS------------------SERLKQIQIETAEAFANGCA
506 EEASIAMLERQ-CNNGKKISSNDTPYS-------------RT-R-EKLELKRERKAARTL
507 AIITGAFLICWLPFFIIALIGPF-VDP-E--GIPPFARSFVLWLGYFNSLLNPIIYTIFS
508 PEFRSAFQ-KIL----------FG---KYRRGHR--------------------------
509 ------------------------------------------------------------
510 ----------------------------------------------------
511 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
512 M-ANFTFGDLALDVARMGGLASTPSGLRS-----------------TGLTTPGLSPTG--
513 ------------------------------LVTS--DFNDSYGLTGQF-IN-GSHS----
514 -----------------SRSRDNAS-ANDT-------------SATNMTDDRYWS-LTVY
515 SHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-M
516 PLSVVSE-IS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIR
517 RRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK--------
518 --GYTIFSTVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETT
519 LVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKK-------------
520 ---NRAKKLPENANGVNSNSSS------------------SERLKQIQIETAEAFANGCA
521 EEASIAMLERQ-CNNGKKISSNDTPYS-------------RT-R-EKLELKRERKAARTL
522 AIITGAFLICWLPFFIIALIGPF-VDP-E--GIPPFARSFVLWLGYFNSLLNPIIYTIFS
523 PEFRSAFQ-KIL----------FG---KYRRGHR--------------------------
524 ------------------------------------------------------------
525 ----------------------------------------------------
526 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
527 M-EGAE-GQEELDWEAL--YLRLP--LQN-----------------CSWNSTGWEPNW--
528 ------------------------------NVTV--VPNTTW-----------WQA----
529 -----------------SAPFDTPA-ALVR-------------AAAK-------------
530 --------AVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-M
531 PLGAVYE-VV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIH
532 ASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV--------
533 --GYQIFATASSFYVPVLIILILYWRIY-------QTARKRIR-----------------
534 ----------------------------RRRGATARGGVGPPP-----------------
535 --------VPAGGALVAGGGSGGIAAAVVAVI--------GRPLPTISETTTTGFTNVSS
536 NNTS---PEKQSCANGLEADPPTTGYGAVAAAYYPSLVRRKP-K-EAADSKRERKAAKTL
537 AIITGAFVACWLPFFVLAILVPT-CDC-E---VSPVLTSLSLWLGYFNSTLNPVIYTVFS
538 PEFRHAFQ-RLL----------CGRRVRRRRAPQ--------------------------
539 ------------------------------------------------------------
540 ----------------------------------------------------
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